Clinical trials: Prolapse
Rectal Prolapse
Pathologic Assessment of Rectal Prolapse in the Young
Patients aging less than 45 years with rectal prolapse will undergo full pathologic and functional assessment to determine the underlying etiology.
- Trial name
- NCT03012464
- Testing
- Pathologic and functional assessment
- Where
- 2 sites in Egypt
- Volunteers
- 10 people
- Sponsor
- Mansoura University
Heart Murmurs, Mitral Valve Prolapse
Automated Algorithm Based Analysis of Phonocardiograms of Newborns
The purpose of this double-blind pivotal clinical utility study is to determine on a large patient population whether heart murmurs can be reliably detected with high sensitivity and specificity using a locked, automated…
- Conditions
- Heart Murmurs, Mitral Valve Prolapse, Systolic Murmurs
- Trial name
- NCT02105480
- Testing
- Computer aided auscultation (CAA)
- Where
- Austria
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- CSD Labs GmbH
Dermatochalasis, Blepharoptosis
Vibration-Assisted Anaesthesia
Aim of study is to investigate whether a small, non-invasive vibrating device applied to the forehead during local anaesthetic administration reduces the pain of the injection.
- Trial name
- NCT00793988
- Testing
- Vibration-assisted anaesthesia, Switched-off vibrating device
- Where
- Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Pelvic Organ Prolapse
Abdominal Sacral Hysteropexy Versus Vaginal Sacrospinous Hysteropexy
The aim of the current study is to compare abdominal sacral cervicopexy with vaginal sacrospinous cervicopexy in women with apical prolapse in terms of operative time, procedures safety and efficacy.
- Trial name
- NCT04850365
- Testing
- Hysteropexy
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Ain Shams University
Ptosis, Eyelid
Comparison of Different Surgical Treatments for Severe Ptosis Correction
Main research purposes of this research is to compare the therapeutic effect and safety of the superior levator muscle shortening combined with the tarsus resection and the traditional frontal muscle flap in the correction of…
- Trial name
- NCT03916107
- Testing
- Levator muscle and tarsus resection, Frontalis flap
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
All Patients Who Have Undergone a Pessary Fitting
Characteristics Predictive of Pessary Success
Pessaries are mechanical support devices worn vaginally to treat the symptoms of pelvic organ prolapse, such as vaginal pressure or a vaginal bulge.
- Trial name
- NCT01123213
- Where
- United States
- Volunteers
- 158 people
- Sponsor
- University of California, Irvine
Pelvic Organ Prolapse
Vaginal Vault Native Tissue Suspension
Vaginal vault suspension at time of abdominal hysterectomy using Mackenrodt and uterosacral ligaments.
- Trial name
- NCT07517965
- Testing
- Mackenrodt uterosacral double ligaments suspension
- Where
- Egypt
- Volunteers
- 10 people
- Sponsor
- Assiut University
Pelvic Organ Prolapse
Laparoscopic Retrovesical Colpopectinopexia
The purpose of this study is to identify whether a new operative technic would be acceptable in female with pelvic organ prolapse.
- Trial name
- prolapse (NCT02919852)
- Testing
- laparoscopic retrovesical colpopectinopexia
- Where
- Ukraine
- Volunteers
- 70 people
- Sponsor
- Orel Regional Hospital, Russia
Amblyopia, Refractive Errors
Vision Screening for the Detection of Amblyopia
INTRODUCTION. Amblyopia is defined as the loss of visual acuity (VA) in one or both eyes, without any obvious structural or pathological anomalies.
- Conditions
- Amblyopia, Refractive Errors, Anisometropia, Strabismus
- Trial name
- NCT01430247
- Testing
- Amblyopia screening
- Where
- Croatia
- Volunteers
- 7,000 people
- Sponsor
- Mladen Busic
Heart Murmurs, Mitral Valve Prolapse
Automatic Differentiation of Innocent and Pathologic Murmurs in Pediatrics
The purpose of this preliminary clinical study is to assess the quality of a computational algorithm that automatically classifies murmurs of phonocardiograms (PCGs) as either pathologic (AHA class I) or as no- or innocent (AHA…
- Conditions
- Heart Murmurs, Mitral Valve Prolapse, Systolic Murmurs
- Trial name
- NCT02512341
- Testing
- Computer Aided Auscultation (CAA)
- Where
- Canada
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- CSD Labs GmbH
Pelvic Floor Disorders, Vaginal Atrophy
Effect of Laser Therapy on Vaginal Tissue
Pelvic floor disorders, including prolapse, incontinence, and vulvovaginal atrophy decrease the quality of life of every fourth woman.
- Trial name
- NCT05898191
- Testing
- vaginal laser treatment
- Where
- Czechia
- Volunteers
- 15 people
- Sponsor
- Institute for the Care of Mother and Child, Prague, Czech Republic
Pelvic Organ Prolapse
Sacrospinous Ligament Fixation With Conventional Surgical Instruments in Chinese Apical Prolapse Female Patients
SSLF is typically a suture-based attachment of the vaginal apex to the sacrospinous ligament, either unilaterally or bilaterally.
- Trial name
- SSLF-CSI (NCT03782285)
- Testing
- sacrospinous Ligament Fixation
- Where
- 9 sites in China
- Volunteers
- 100 people
- Sponsor
- Peking Union Medical College Hospital
Prolapse
Evaluation of 3D Translabial Ultrasound Imaging for Pessary Size Estimation
Symptoms of female pelvic floor dysfunction, such as incontinence and pelvic organ prolapse, can be alleviated by using pessaries, which are passive medical devices that are inserted in the vagina to support the pelvic organs.
- Trial name
- NCT04099121
- Testing
- Ultrasound Imaging
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- Western University, Canada
Pelvic Organ Prolapse
Polypropylene Mesh in Prolapse Surgery
The purpose of this study was to report the long-term objective and subjective outcome after prolapse surgery with polypropylene mesh.
- Trial name
- NCT02383199
- Volunteers
- 161 people
- Sponsor
- Turku University Hospital
Rectal Prolapse
Intra-operative Adverse Events During Laparoscopic Ventral Mesh Rectopexy
Outcomes of laparoscopic ventral mesh rectopexy are well known, but data on intra-operative adverse events is scant. A multicenter pool-analysis of prospectively collected database on 1384 patients with internal/external rectal…
- Trial name
- NCT02870192
- Testing
- Laparoscopic ventral mesh rectopexy
- Volunteers
- 200 people
- Sponsor
- University of Rome Tor Vergata
Pelvic Organ Prolapse
A Novel Approach to Posterior Mesh Fixation in Laparoscopic Sacral Colpopexy
This randomized controlled study is designed to test the non inferiority of no attachment of posterior mesh compared to fixation of posterior mesh to the vagina in laparoscopic sacral colpopexy in terms of anatomical correction…
- Trial name
- NCT04358978
- Testing
- laparoscopic sacral colpopexy with posterior mesh no attachment, laparoscopic sacral colpopexy with posterior mesh attachment
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- Catholic University of the Sacred Heart
Genital Prolapse
Modified Technique in Sacrospinous Fixation for Treatment of Apical Genital Prolapse
Pelvic organ prolapse is one of the most common benign gynecological disorders and affects approximately 40% of women over 50 years of age.
- Trial name
- NCT05691543
- Testing
- sacrospinous fixation Using Posterior Vaginal wall flap
- Volunteers
- 15 people
- Sponsor
- Assiut University
Pelvic Organ Prolapse
Comparison of 2 Lightweight Y-meshes After Laparoscopic Sacrocolpopexy
The purpose of the study is to determine the clinical cure rates of pelvic organ prolapse from subjects that had a robotic-assisted sacrocolpopexy using Alyte Y mesh and Restorelle Y smartmesh lightweight mesh.
- Trial name
- NCT02248935
- Where
- United States
- Volunteers
- 316 people
- Sponsor
- Atlantic Health System
Degree of Uterine Prolapse and Its Effect on Quality of Life
Quality of Life Assessment in Patients With Different Degrees of Pelvic Organ Prolapse
Study design: The study building by two design a descriptive exploratory research design and quasi experimental research design were utilized in the present study Setting of the study: This study was conducted at the Outpatient…
- Trial name
- NCT07080203
- Where
- Egypt
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Sohag University
Rectal Prolapse
Comparative Study Between Delorme Operation With or Without Postanal Repair in Treatment of Complete Rectal Prolapse
The aim of the study is to compare Delorme operation alone or with post anal repair and levatorplasty for treating complete rectal prolapse.consecutive patients who were treated for complete rectal prolapse at the Colorectal…
- Trial name
- NCT01656369
- Testing
- Group I: delorme operation only., delorme operation with post anal repair
- Where
- Egypt
- Volunteers
- 82 people
- Sponsor
- Mansoura University