Clinical trials: Prophylactic
Malaria, Pregnancy
Impact of IPT With Sulfadoxin Pyrimetamin on Pregnant Women and Their Babies Outcomes in Peri-urban Areas of Bobo-Dioulasso(Burkina Faso)
The purpose of this is to determine the impact of intermittent preventive treatment (IPT) with sulfadoxine-pyrimethamine (SP) on the morbidities associated with malaria in pregnant women and newborns in rural peri-urban areas of…
- Trial name
- NCT01255605
- Where
- Burkina Faso
- Volunteers
- 772 people
- Sponsor
- Université Polytechnique de Bobo-Dioulasso
Social Support, Screen Time
The Green Prescription Program for Increasing Physical Activity in Adolescents
This study evaluated the effectiveness of the Green Prescription, a school-based behavioral intervention that incorporated health education, designed to increase physical activity among adolescents aged 15-17 years who were…
- Conditions
- Social Support, Screen Time, Physical Inactivity, Sedentary Lifestyle
- Trial name
- NCT07770997
- Testing
- Green Prescription (Teacher-Led), Green Prescription (Interdisciplinary)
- Where
- Poland
- Volunteers
- 308 people, healthy volunteers welcome
- Sponsor
- Poznan University of Physical Education
Hematologic Neoplasms
Donor Lymphocyte Infusion After Allogeneic Hematopoietic Cell Transplantation for High-Risk Hematologic Malignancies
Background: People with blood cancers often receive blood or bone marrow transplants. But even with these treatments, the risk of relapse is high.
- Trial name
- NCT05327023
- Testing
- donor lymphocyte infusion, Cyclophosphamide, Busulfan
- Where
- United States
- Volunteers
- 430 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
HIV Infections
Screen2Prevent (S2P)
Screen2Prevent is a study intended to improve HIV prevention and detection through implementation and evaluation of three different broad-scale HIV screening approaches a) targeted, b) universally offered opt-in, and c)…
- Trial name
- S2P (NCT07728123)
- Testing
- HIV screening strategies
- Where
- 5 sites in United States
- Volunteers
- 84,000 people, healthy volunteers welcome
- Sponsor
- Westat
Traffic Accident, Chronic Disease
Risk Level of Suffering From Traffic Injury in Primary Health Care: LESIONAT Project
Main objectives: To know the distribution of risk elements of traffic injuries Secondary objectives: To study the distribution of risk elements related with the possibility of suffering from a TI in relation to medication…
- Conditions
- Traffic Accident, Chronic Disease, Prevalence of Psychoactive Substances in Road Traffic, Relative Risk Estimation of Accident for Impaired Drivers
- Trial name
- LESIONAT (NCT00778440)
- Where
- Spain
- Volunteers
- 1,540 people, healthy volunteers welcome
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Educational and Preventive Session for Dental Caries, Oral Diseases
Oral Health Promotion Program in Schools in Polígono Sur
The objective of this observational study is to evaluate oral health before and after conducting an educational session on oral hygiene in schoolchildren from 3 schools in the Polígono Sur of Seville.
- Trial name
- OHPPSPS (NCT06797778)
- Where
- Spain
- Volunteers
- 396 people, healthy volunteers welcome
- Sponsor
- University of Seville
Leukemia
Prophylactic Infusion of Donor Lymphocytes in Cord Blood Transplantation
Pilot, multicentric, open-label, single-arm, phase I-II clinical trial to evaluate the safety and efficacy of a novel Umbilical Cord Blood Transplantation (UCBT) platform, that consists of a UCBT of the 80 fraction, followed by a…
- Trial name
- NCT02328885
- Testing
- DLI of the 20 fraction of the UCBT
- Where
- 5 sites in Spain
- Volunteers
- 17 people
- Sponsor
- Banc de Sang i Teixits
Celiac Disease in Children
"Adding DNA-test for Screening of HLA-DQ2 and DQ8 to Improve Early Diagnosis of Celiac Disease"
Celiac Disease (CD) is an immune-mediated systemic disorder elicited by the ingestion of gluten containing cereals from the normal diet, among others wheat, rye and barley.
- Trial name
- GLUTEN-GEN (NCT06179121)
- Testing
- DNA test for screening HLA-DQ2 and DQ8 from dried blood spots to early detect Celiac Disease
- Where
- Netherlands
- Volunteers
- 508 people
- Sponsor
- Leiden University Medical Center
Pediatric Cancer, Cancer Survivor
LOG-I - Impact Study of LOG-AFTER Software on Long-term Monitoring of Former Patients (LOG-I - LOG-Impact Study)
Childhood cancer survivors represent a high-risk population that requires risk-based follow-up. Follow-up recommendations have been harmonized.
- Conditions
- Pediatric Cancer, Cancer Survivor, Hemato-oncologic Patients
- Trial name
- LOG-I (NCT06939322)
- Testing
- Use of the Log-AFTER software
- Where
- France
- Volunteers
- 320 people
- Sponsor
- University Hospital, Angers
HIV Positive, Herpes Simplex, Genital
Safety and Efficacy of Famciclovir in HIV1 Positive Adults With Recurrent Genital Herpes
To determine the efficacy of Famvir 500mg bd as suppressive antiviral therapy for acute genital Herpes simplex virus (HSV) outbreaks in HIV subjects.
- Trial name
- NCT01154543
- Volunteers
- 42 people
- Sponsor
- Holdsworth House Medical Practice
Wound Infection, Wound Dehiscence
Honey Dressing - A Preventive Procedure for Post-Surgical Site Infection.
The goal of this clinical trial is to compare the wound healing in the participants who underwent the clean surgical procedure, by applying honey dressing and common Iodine solution dressing, participants will have no other…
- Conditions
- Wound Infection, Wound Dehiscence, Wound Bleeding, Wound Surgical
- Trial name
- NCT06220344
- Testing
- Honey Dressing, Iodine Dressing
- Where
- Pakistan
- Volunteers
- 80 people
- Sponsor
- HITEC-Institute of Medical Sciences
Intermittent Preventive Treatment, Placental Malaria
Sulphadoxine-Pyrimethamine for Intermittent Preventive Treatment of Malaria in Pregnancy in Uganda
The effectiveness of sulfadoxine-pyrimethamine (SP) as intermittent preventive treatment in pregnancy in malaria-endemic areas the effectiveness and efficacy of SP may be compromised by increased SP resistance.
- Trial name
- SP IPTp (NCT01184911)
- Testing
- Sulfadoxine-pyrimethamine
- Where
- Uganda
- Sponsor
- University of California, San Francisco
Mechanical Complication of Peritoneal Dialysis Catheter
Prophylactic Omentopexy During Laparoscopic Insertion of Peritoneal Dialysis Catheter
The purpose of this study is to compare function of the peritoneal dialysis catheter in two groups of patients with and without prophylactic omentopexy that was performed during laparoscopic insertion of peritoneal catheters.
- Trial name
- NCT02879734
- Testing
- Prophylactic laparoscopic omentopexy
- Where
- Iran
- Volunteers
- 40 people
- Sponsor
- Tehran University of Medical Sciences
Fibrinogen, Spine Deformity
Effect of Prophylactic Fibrinogen Concentrate In Scoliosis Surgery
EFISS is a prospective, randomized, placebo-controlled trial testing the feasibility, safety and efficacy of prophylactic administration of fibrinogen in paediatric spinal surgery.
- Conditions
- Fibrinogen, Spine Deformity, Coagulopathy, Consumption, Bleeding
- Trial name
- EFISS (NCT05391412)
- Testing
- Fibrinogen Concentrate Human
- Where
- Czechia
- Volunteers
- 32 people
- Sponsor
- Brno University Hospital
HIV Infections
A Study of Zidovudine in the Prevention of HIV Infection in Individuals Exposed to the Virus
To prevent individuals who have had a massive accidental exposure to HIV from becoming infected with HIV and possibly developing AIDS, by treating them with zidovudine (AZT).
- Trial name
- NCT00000993
- Testing
- Zidovudine
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Atrial Fibrillation
Amiodarone to Prevent Post-Operative Arrhythmias
Rapid heart rhythms originating from the upper heart chambers (atrial tachyarrhythmias) are very common after open-heart surgery.
- Trial name
- NCT00251706
- Testing
- amiodarone
- Where
- Canada
- Volunteers
- 600 people
- Sponsor
- University of Calgary
Malaria
Effectiveness of Intermittent Preventive Treatment for Malaria in Children
Intermittent preventive treatment for malaria in children (IPTc) is a promising new approach to malaria control. Preliminary studies of IPTc in Senegal and Mali indicate that this approach can be very effective.
- Trial name
- NCT00119132
- Testing
- artesunate-amodiaquine, sulphadoxine-pyrimethamine
- Where
- Ghana
- Volunteers
- 2,602 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Hemophilia A
Safety, Efficacy Evaluation of Recombinant Coagulation Factor VIII Injection in Subjects With Hemophilia A.
This is a multi-center, open-label, single-arm trial to evaluate the efficacy and safety of Recombinant Coagulation Factor VIII in patients with hemophilia A .
- Trial name
- NCT04061109
- Testing
- Recombinant Human Coagulation FVIII
- Where
- 11 sites in China
- Volunteers
- 64 people
- Sponsor
- Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
Toothbrushing, Dental Plaque
BEhavioral EConomics for Oral Health iNnovation Pilot Trial
This Phase I randomized pilot trial will assess the efficacy of a fixed incentive payment program and drawing incentive payment program versus a control program to promote early childhood caries (ECC) preventive health behaviors…
- Conditions
- Toothbrushing, Dental Plaque, Parent-Child Relations, Oral Hygiene
- Trial name
- BEECON Pilot (NCT03862443)
- Testing
- Fixed Incentive, Drawing Incentive
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Head and Neck Neoplasms, Wound Infection
Role of Prophylactic Antibiotics in New Introducer PEG-Gastropexy
Peristomal infections are the commonest complications of PEG despite prophylactic antibiotics which may result in emergence of resistant micro-organisms like Methicillin resistant Staphylococcus aureus (MRSA).
- Trial name
- NCT00375414
- Testing
- PEG-Gastropexy
- Where
- Germany
- Volunteers
- 97 people
- Sponsor
- Johann Wolfgang Goethe University Hospital