Clinical trials: Prophylaxis
Type 1 Diabetes
Effects of Vitamin D Supplementation in Subjects With New Onset of Type 1 Diabetes
In this placebo controlled study the investigators aim to investigate the effects of vitamin D supplementation in subjects with new onset of type 1 diabetes on immunological, endocrine and metabolic parameters.
- Trial name
- NCT01390480
- Testing
- Cholecalciferol
- Where
- Austria
- Volunteers
- 31 people
- Sponsor
- Medical University of Graz
Malaria
Community Point Distribution of Insecticide Treated Bed Nets
All households in three zones in Zambia's Eastern Province were invited to attend a community point distribution of insecticide treated bed nets (ITNs).
- Trial name
- NCT02517879
- Testing
- Community point distribution, Community health worker hang-up visit
- Volunteers
- 560 people, healthy volunteers welcome
- Sponsor
- IDinsight
Substance-Related Disorders, Recidivism
Alliances to Disseminate Addiction Prevention and Treatment (ADAPT)
Youth involved in the juvenile justice system (YJJ) bear a disproportionate burden of the addiction crisis. YJJ substance use (SU) is extremely prevalent, with a third of YJJ meeting criteria for a substance use disorder (SUD).
- Conditions
- Substance-Related Disorders, Recidivism, Opioid-Related Disorders, Substance Use
- Trial name
- ADAPT (NCT04499079)
- Testing
- Learning Health System
- Where
- United States
- Volunteers
- 7,316 people
- Sponsor
- Indiana University
Human Immunodeficiency Virus
Mobile-health (mHealth) Intervention to Support HIV Self-testing and PrEP Uptake Among Young Men Who Have Sex With Men
The proposed study will involve adolescent (17-24 years old) men who have sex with men (described as YMSM hereafter) who meet eligibility criteria to participate.
- Trial name
- NCT04865341
- Testing
- IMB, Information-Only Control
- Where
- United States
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
Aneurysm, Vasospasm
Balloon Prophylaxis of Aneurysmal Vasospasm
The purpose of this study is to determine if early transluminal ballooning of the major cerebral arteries prevents severe vasospasm and improves neurological outcome in patients with Fisher Grade III aneurysmal subarachnoid…
- Trial name
- NCT00282893
- Testing
- transluminal ballooning, currently existing therapies for the treatment of vasospasm
- Where
- 5 sites in United States, Canada and 1 more
- Volunteers
- 170 people
- Sponsor
- University of California, Davis
NEC - Necrotizing Enterocolitis
Multidimensional Dynamic Early Warning System for Neonatal Necrotizing Enterocolitis: A Multicenter Clinical Study
Necrotizing enterocolitis (NEC) is one of the most severe gastrointestinal emergencies in preterm infants, characterized by insidious onset, rapid progression, and high mortality.
- Trial name
- NCT07545993
- Testing
- No Intervention: Observational Cohort
- Volunteers
- 1,050 people
- Sponsor
- Guangzhou Women and Children's Medical Center
Type 1 Diabetes
BABYDIET-Study - Primary Prevention of Type 1 Diabetes in Relatives at Increased Genetic Risk
The major goals of this project are to determine whether primary intervention through delayed introduction of dietary gluten is feasible and could reduce the incidence of islet autoimmunity in high-risk first degree relatives of…
- Trial name
- NCT01115621
- Testing
- Glutenfree diet during the first year of life
- Where
- Germany
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Institut fur Diabetesforschung, Munich, Germany
Cirrhosis
Primary Prophylaxis of Gastric Varix Bleed
In patients who have never bled from gastric varix (GOV2 and IGV1), cyanoacrylate injection will be better than both beta-blocker therapy and no treatment in prevention of gastric variceal bleed.
- Trial name
- NCT00905996
- Testing
- Endoscopic cyanoacrylate injection, Beta-blocker (propranolol)
- Where
- India
- Volunteers
- 74 people
- Sponsor
- Govind Ballabh Pant Hospital
Myopia
Effects of 650nm Low Energy Light on Human Retina and Choroid Microcirculation
This project is a single-center, prospective, self-controlled clinical study. It intends to select patients with simple medium and low degree myopia as subjects, and apply 650nm low-energy red light irradiation to the retina to…
- Trial name
- NCT04604405
- Testing
- photobiomodulation
- Where
- China
- Volunteers
- 126 people
- Sponsor
- Central South University
Tobacco Prevention
Effectiveness of Comics to Promote Tobacco-related Knowledge, Attitudes and Behaviours Among Primary School Students
The goal of this pilot RCT is to evaluate the effectiveness of comics containing tobacco-related content in improving tobacco-related knowledge and attitudes among Hong Kong primary school students.
- Trial name
- NCT07453745
- Testing
- Tobacco-related comics, Conventional health leaflet
- Where
- Hong Kong
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Academic Performance; Primary Prevention; Physical Activity
Active Smarter Kids: A Cluster-randomized Controlled Trial
The relationship between physical activity and academic performance has received widespread attention owing to the pressure on schools to graduate pupils who meet accepted academic standards.
- Trial name
- ASK (NCT02132494)
- Testing
- Physical activity
- Where
- Norway
- Volunteers
- 1,202 people
- Sponsor
- Western Norway University of Applied Sciences
Dental Caries and Streptococcus Mutans Count
Impact of Maternal Xylitol Consumption on Mutans Sterptococci
The study was designed to determine whether maternal xylitol consumption through regular chewing of xylitol gums can affect the salivary mutans streptococci (MS), dental caries, and dental plaque levels of their children.
- Trial name
- NCT02036151
- Testing
- xylitol, fluoride varnish application
- Where
- Saudi Arabia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
Tetanus, Hepatitis B
Lot-to-lot Consistency of Tritanrix™-HepB/Hib-MenAC & Its Non-inferiority vs Tritanrix™-HepB/Hiberix™ in Infants
The primary purpose of this study is to demonstrate the lot-to-lot consistency of 3 production lots of GSK Biologicals' Hib-MenAC (Haemophilus influenzae type b and meningococcal serogroups A and C) vaccine when reconstituted…
- Conditions
- Tetanus, Hepatitis B, Haemophilus Influenzae Type b, Whole Cell Pertussis
- Trial name
- NCT00197275
- Testing
- Hib-MenAC mixed with Tritanrix™-HepB
- Where
- 3 sites in Thailand
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Osteoporosis
Calcium and Bone Mass in Young Females
We originally suggested that calcium in the diet is important in determining the amount of bone (bone mass) that builds up in young adults. We are testing the effect of calcium on bone mass in 354 Caucasian (white) girls.
- Trial name
- NCT00000402
- Testing
- Calcium
- Where
- United States
- Volunteers
- 354 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Obesity, Cardiovascular Diseases
A Clinical Trial Of Two Educational Strategies In Cardiovascular Health In Child Population
AIM: To evaluate the effectiveness of two strategies in cardiovascular risk in children 2º grade in the community of Madrid. DESIGN: cluster-randomized trial with blinded evaluator SCOPE AND SUBJECTS OF STUDY: Children of both…
- Trial name
- SAVINHEARTS (NCT01418872)
- Testing
- Didactic Concerts
- Where
- Spain
- Volunteers
- 1,730 people, healthy volunteers welcome
- Sponsor
- Agencia Lain Entralgo
Bile Duct Stricture
Suspended Overlength Biliary Stents Preventing Duodenobiliary Reflux in Patients With Biliary Stricture
Endoscopic insertion of plastic or metal stents in bile duct under endoscopic retrograde cholangiopancreatography is a well established treatment of distal malignant biliary obstruction.Biliary stents are widely used to relieve…
- Trial name
- NCT03310554
- Testing
- 26cm suspended overlength biliary stents, 30cm suspended overlength biliary stents, ordinary plastic biliary stents
- Where
- China
- Volunteers
- 117 people
- Sponsor
- Peking University Third Hospital
Obesity, Type 2 Diabetes
Feel4Diabetes-study
The aim of the Feel4Diabetes-study is to develop, implement and evaluate a community-based intervention aiming to create a more supportive social and physical environment to promote lifestyle and behaviour change to prevent type…
- Trial name
- Feel4Diabetes (NCT02393872)
- Testing
- Feel4Diabetes-intervention
- Where
- Greece
- Volunteers
- 9,000 people, healthy volunteers welcome
- Sponsor
- Harokopio University
Mental Health Promotion, Emotional Intelligence
Two Tutorial Action Programs, Incidental and Structured, on the General Welfare of Elementary School Students.
The aim of this paper is twofold: on the one hand, to test the effectiveness of a structured emotional education program in second, third and fourth grade primary school students and, on the other hand, to test the differential…
- Conditions
- Mental Health Promotion, Emotional Intelligence, Self-Concept, Emotional and Behavioral Problems
- Trial name
- NCT06131229
- Testing
- Structured emotional education program (PEE), Incidental tutorial action based on the school's regular curriculum (PCO)
- Where
- Spain
- Volunteers
- 157 people, healthy volunteers welcome
- Sponsor
- OIHANA SAGASTI ARRIEN
Adverse Childhood Experiences, Family Functioning
The THRIVE Study: Teaching Healthy Regulation in Individuals & Vulnerable Environments
The goal of this 2-arm randomized control trial is to determine the impact of a community health worker delivered coaching intervention, GRIT, on preventing the early initiation of regular use of alcohol and cannabis among…
- Trial name
- NCT06821035
- Testing
- Garnering Resilience in Traumatized youth and families (GRIT), Digital Citizenship Curriculum (DCC)
- Where
- United States
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
HIV
PHAT Life: Preventing HIV/AIDS Among Teens in Juvenile Justice
PHAT Life: Preventing HIV/AIDS Among Teens, is a uniquely-tailored intervention designed for recently-arrested juvenile offenders on probation.
- Trial name
- PHAT Life (NCT02647710)
- Testing
- PHAT Life Intervention, Health Promotion Control
- Where
- United States
- Volunteers
- 349 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
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