Clinical trials: Prophylaxis
Chemotherapy-induced Alopecia
Prevention of Alopecia in Patients With Localised Breast Cancer
The prevention of chemotherapy-induced alopecia (CIA) is still imperfectly managed in France. Strengthening the evidence base on the benefits of strategies to prevent CIA, based on robust methodologies, remains a prerequisite for…
- Trial name
- ICELAND (NCT06011525)
- Testing
- standard cold cap, scalp-cooling technique
- Where
- 3 sites in France
- Volunteers
- 196 people
- Sponsor
- Centre Francois Baclesse
HPV Infection, Vaccine-Preventable Diseases
Game-Based Intervention to Promote HPV Vaccination
This study will examine the feasibility and acceptability of an innovative game-based intervention designed for families of youth aged 11-14 to promote HPV vaccination; will explore changes in key outcomes and related measures…
- Trial name
- NCT06162676
- Testing
- HPV game
- Where
- United States
- Volunteers
- 133 people, healthy volunteers welcome
- Sponsor
- Michigan State University
Whole Cell Pertussis, Haemophilus Influenzae Type b
Response to GSK Biologicals' Tritanrix-HepB/Hib-MenAC Vacc (4th Dose) at 15-24m & Mencevax ACWY at 24-30m
The purpose of the study is to evaluate the immunogenicity, safety and reactogenicity of a booster dose of DTPw-HBV/Hib-MenAC compared to DTPw-HBV/Hib given to healthy subjects at 15 to 24 months of age primed with 3 doses of…
- Conditions
- Whole Cell Pertussis, Haemophilus Influenzae Type b, Hepatitis B, Diphtheria
- Trial name
- NCT00136604
- Testing
- Tritanrix-HepB/Hib-MenAC, Mencevax ACWY, Tritanrix-HepB/Hiberix
- Where
- 3 sites in Thailand
- Volunteers
- 617 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Mycobacterium Avium-intracellulare Infection, HIV Infections
A Study to Evaluate the Effects of Azithromycin on MAC Disease Prevention in HIV-Positive Patients
This study is designed to find out whether HIV-positive patients whose immune systems have improved after receiving anti-HIV treatment should take azithromycin to prevent Mycobacterium avium complex (MAC) disease.
- Trial name
- NCT00000947
- Testing
- Azithromycin
- Where
- 19 sites in United States
- Volunteers
- 850 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Chemotherapy Induced Nausea and Vomiting, Pediatric Cancer Patients
Comparative Study of Fosaprepitant and Aprepitant for the Prevention of Chemotherapy-induced Nausea and Vomiting in Pediatric Caner Patients
Children aged 2-12 years scheduled to receive moderately or highly emetogenic chemotherapy were randomly assigned to arm-A (fosaprepitant) or arm-B (aprepitant).
- Trial name
- NCT04873284
- Testing
- fosaprepitant, aprepitant, Granisetron plus dexamethasone
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Shanghai Children's Medical Center
Skin Diseases
Topical Therapy for Prevention of Infections in Preterm Infants
The purpose of this study is to determine how to best take care of the skin of preterm infants in order to prevent infections through the skin.
- Trial name
- NCT00162747
- Testing
- Aquaphor, Sunflower Seed Oil
- Where
- Bangladesh
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Schizophrenia, Prodrome
Indicated Prevention With Omega-3 Fatty Acids in Adolescents With 'At-Risk-Mental-State' for Psychosis
Early intervention in psychosis might be associated with better outcomes. However, intervention in the pre-psychotic phase has been questioned as, using current criteria, only 20-50% of individuals classified as prodromal develop…
- Trial name
- NCT00396643
- Testing
- Omega 3 fatty acids
- Where
- Austria
- Volunteers
- 81 people
- Sponsor
- Medical University of Vienna
Neonatal Staphylococcal Sepsis
Safety and Pharmacokinetics Study in VLBW Neonates With BSYX-A110
"Phase I/II, Randomized, Double Blind, Placebo Controlled, Dose Escalating, Safety and Pharmacokinetics Study in Very Low Birth Weight Neonates of Four Doses of BSYX-A110 for the Prevention of S.
- Trial name
- N002 (NCT00631878)
- Testing
- Pagibaximab (formerly BSYX-A110)
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- Biosynexus Incorporated
Stickler Syndrome Type 1, Stickler Syndrome Type 2
Retinal Detachment Prevention (Laser Prophylaxis) in Stickler Syndrome (SS)
The goal of this clinical trial is to prospectively document to what extent the OSC/SS prophylactic laser retinopexy procedure works to prevent retinal detachment in SS in children and adults.
- Trial name
- OSC/SS (NCT07146516)
- Testing
- Prophylactic (non-invasive) Laser Retinopexy
- Where
- 6 sites in United States
- Volunteers
- 500 people
- Sponsor
- Helen Keller Eye Research Foundation
Infant, Premature, Hypothermia, Newborn
Cardboard Cot in Neonatal Thermoregulation: A Randomized Cross Over Trial
This study will determine whether the efficacy of Mylar-lined cardboard cots is equivalent to traditional incubators in their ability to prevent hypothermia (axillary temperature < 36° C) in preterm neonates <36 6/7 weeks…
- Trial name
- CCot (NCT03344978)
- Testing
- Cardboard Cot Care, Incubator Care
- Sponsor
- University of Alabama at Birmingham
Malaria
Intermittent Preventative Treatment With Sulfadoxine-Pyrimethamine in Gambian Multigravidae
Malaria is particularly harmful during pregnancy causing anemia in the mother and low birth weight which, in turn, increases infant mortality.
- Trial name
- NCT00120809
- Testing
- Sulfadoxine-pyrimethamine
- Where
- The Gambia
- Volunteers
- 3,000 people
- Sponsor
- London School of Hygiene and Tropical Medicine
Anemia
Treatment and Prevention of Anemia With Ferrous Sulfate Plus Folic Acid in Children in Goiania - Goias, Brazil
Iron deficiency anemia is the most common nutritional problem in the world. The objectives of this study are: to evaluate the prevalence of anemia in children from 6 to 24 months of age and the therapeutic and prophylactic…
- Trial name
- NCT00701246
- Testing
- ferrous sulfate, folic acid
- Where
- Brazil
- Volunteers
- 196 people
- Sponsor
- Universidade Federal de Goias
HIV Infections, Pregnancy
A Study of Nevirapine to Prevent HIV Transmission From Mothers to Their Babies
The purpose of this study is to see if giving the anti-HIV drug nevirapine (NVP) to HIV-positive pregnant women and their babies can help reduce the chance that a mother will give HIV to her baby during delivery.
- Trial name
- NCT00000942
- Testing
- Nevirapine
- Where
- 5 sites in France, Italy and 2 more
- Volunteers
- 1,244 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Cerebral Palsy, Spastic
Application of 3D Scanner to Measure Physical Size in Patients With Severe Cerebral Palsy
The aim of this study is to improve the manufacturing techniques of hip brace in preventing progressive hip displacement in patients with severe cerebral palsy, through the measurement of patient's physical size using a 3D…
- Trial name
- NCT05388422
- Testing
- Application of 3D scanner to measure physical size in patients with severe cerebral palsy
- Where
- South Korea
- Volunteers
- 19 people
- Sponsor
- Seoul National University Hospital
All
Family History in a Singaporean Healthy Population
The purpose of this study is to better understand the linkages between family health history (FHH) and genomics in a Singaporean population.
- Trial name
- NCT03114553
- Testing
- MeTree
- Where
- Singapore
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Duke University
Prevention of Mother-to-child Transmission of HIV
Retention of Women in the PMTCT (Prevention of Mother-to-child Transmission of HIV)
EXECUTIVE SUMMARY RESEARCH QUESTION TO BE ADDRESSED BY THIS PROPOSAL What are the factors associated with retention-in-care of women enrolled in the eMTCT Option B+ program at eMTCT (elimination of mother-to-child transmission of…
- Trial name
- NCT03213223
- Where
- Zimbabwe
- Volunteers
- 468 people, healthy volunteers welcome
- Sponsor
- University of Zimbabwe
Toxoplasmosis, Cerebral, HIV Infections
A Randomized Prospective Study of Pyrimethamine Therapy for Prevention of Toxoplasmic Encephalitis in HIV-Infected Individuals With Serologic Evidence of Latent Toxoplasma Gondii Infection
To evaluate pyrimethamine as a prophylactic agent against toxoplasmic encephalitis in individuals who are coinfected with HIV and latent Toxoplasma gondii.
- Trial name
- NCT00000666
- Testing
- Pyrimethamine
- Where
- 16 sites in United States
- Volunteers
- 600 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Infections, Rotavirus
To Evaluate Immunogenicity, Reactogenicity & Safety of 2 Doses of GSK Bio HRV Liquid Vaccine Given to Infants (Vietnam)
To provide specific data on immunogenicity of GSK Biologicals' HRV liquid vaccine, when co-administered with the routine Expanded Program of Immunization (EPI) in Vietnam.
- Trial name
- NCT00345956
- Testing
- Human rotavirus liquid vaccine
- Where
- 2 sites in Vietnam
- Volunteers
- 375 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Depression
Effectiveness Trial of the French Blues Indicated Depression Prevention Program
The purpose of this pilot study is to test the effectiveness of French adaptation of the Blues program, a school-based indicated depression prevention intervention.
- Trial name
- French Blues (NCT02731053)
- Testing
- Blues program
- Where
- Canada
- Volunteers
- 72 people
- Sponsor
- Université de Montréal
Graft vs Host Disease, Malignancy
Abatacept as GVHD Prophylaxis Phase 2
This is a phase II multi-center, randomized, double blind, placebo-controlled trial. The investigators are doing this study to see if a new drug, abatacept, can be used together with a calcineurin inhibitor (cyclosporine or…
- Trial name
- NCT01743131
- Testing
- Abatacept
- Where
- 14 sites in United States, Canada
- Volunteers
- 186 people
- Sponsor
- Boston Children's Hospital
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.