Clinical trials: Prophylaxis
Osteoporosis
Osteoporosis Prevention: Changes to Exercise and Diet in Children
The purpose of this study is to determine whether educating parents about health and behavior management techniques will increase physical activity, calcium intake, fitness, and bone density in their children.
- Trial name
- NCT00063050
- Testing
- Physical activity and nutrition intervention
- Where
- United States
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- San Diego State University
Hemophilia A
Evaluate Efficacy and Safety of ADVATE in the Standard Prophylaxis Treatment of Severe or Moderately Severe Hemophilia A
Based on the successful pioneer work of Dr Nilsson and her colleagues in Sweden that started in the late 1950's, prophylaxis is recommend as the standard of care for boys with severe haemophilia by WHO and World Federation of…
- Trial name
- NCT02282410
- Testing
- ADVATE
- Volunteers
- 15 people
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Herpes Simplex Virus Infection, Varicella Zoster Virus Infection
Pharmacokinetics of Valacyclovir Oral Solution in Children
Valacyclovir has replaced acyclovir in many clinical scenarios. Pharmacokinetic data support the use of oral valacyclovir in children, but practical problems exist in children having to take adult-dose tablets.
- Trial name
- VALID2 (NCT04081480)
- Testing
- Valacyclovir
- Where
- Netherlands
- Volunteers
- 7 people
- Sponsor
- Radboud University Medical Center
Cardiovascular Diseases, Dyslipidemias
NUTS for the Prevention of Cardiovascular Disease in Chinese Adults
This study evaluates the feasibility of walnuts supplementation among population of high CVD risks over a period of 6 months. 70 participants will be controls receiving non-edible gifts.
- Trial name
- NUTS (NCT04037943)
- Testing
- Walnuts 30 grams, Walnuts 60 grams
- Where
- China
- Volunteers
- 210 people
- Sponsor
- The George Institute for Global Health, China
Substance Use, HIV/AIDS
Trauma Informed Prevention for Substance Use and Risky Sex
The purpose of this research study is to determine the usefulness of the TIPS iPad app in the treatment of adolescent patients who qualify for Trauma Focused-Cognitive Behavioral Therapy (TF-CBT).
- Trial name
- TIPS (NCT03710720)
- Testing
- TIPS app, Trauma Focused-Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Medical University of South Carolina
Neurosensory Function of Inferior Alveolar Nerve
Assessment of Nerve Function After Mandible Surgery With a Modified Bilateral Sagittal Split Osteotomy Technique
Several technical modifications based on the anatomical position of the neurovascular bundle and its bony mandibular canal have been developed, aiming to prevent injury to the intraalveolar nerve We hypothesized that the…
- Trial name
- NCT02634840
- Testing
- bilateral sagittal split osteotomy
- Volunteers
- 57 people
- Sponsor
- Chang Gung Memorial Hospital
HIV Infections
Male Partner Involvement in the Prevention of MTCT of HIV
The study aims to invite male sexual partners to attend antenatal clinic with their pregnant partners to either acquire pregnancy information or undergo voluntary counselling and testing for HIV.
- Trial name
- NCT00405990
- Testing
- Voluntary counselling and HIV testing in ANC for PMTCT, VCT
- Where
- South Africa
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Substance-Related Disorders, Underage Drinking
Testing a Brief Substance Misuse Preventative Intervention for Parents/Guardians of 5th-7th Grade Students
The current study aims to test the efficacy of a family communication-based, novel, adaptable, and resource-efficient substance misuse preventive intervention for parents/guardians of pre/early adolescents (grades 5-7).
- Conditions
- Substance-Related Disorders, Underage Drinking, Drug Use
- Trial name
- NCT03925220
- Testing
- The SUPPER Project, Improving nutrition and physical activity among youth
- Where
- United States
- Volunteers
- 402 people, healthy volunteers welcome
- Sponsor
- Tufts University
Child Safety, Injury Prevention
Effectiveness of Internet-based Injury Prevention Program in Enhancing Mother's Knowledge on Child Safety
Background: Provision of anticipatory guidance to parents is recommended as an effective strategy to prevent injuries among young children.
- Conditions
- Child Safety, Injury Prevention, Internet-based Intervention, Anticipatory Guidance
- Trial name
- NCT02835768
- Testing
- Internet-based injury prevention program
- Volunteers
- 1,012 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Adolescent Behavior
I-ACT With Check Yourself
Adolescents have some of the highest rates of risk behaviors of all age groups and health behaviors developed in adolescence can persist into adulthood.
- Trial name
- NCT02764190
- Testing
- I-ACT with Check Yourself
- Where
- United States
- Volunteers
- 302 people, healthy volunteers welcome
- Sponsor
- Seattle Children's Hospital
Substance Use, Adolescent Problem Behavior
Randomized Trial of a Data-driven Technical Assistance System for Drug Prevention Coalitions
This project is designed to test the Coalition Check-Up (CCU)-a theory-based and data-driven technical assistance (TA) system that supports community coalitions' implementation of evidence-based programs (EBPs) for drug…
- Trial name
- NCT04592120
- Testing
- Coalition Check-Up
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- The University of Texas Health Science Center, Houston
Childhood Obesity Prevention
i-MaCHeL Study is a Two-group, Cluster-RCT, Involves 460 Preschool's Child-parent Dyads, to Prevent Childhood Obesity
Background: Strategies to treat and prevent obesity are urgently required in Malaysia, and it is now considered a public health priority.
- Trial name
- i-MaCHeL (NCT04711525)
- Testing
- Experimental Group: Interactive Malaysian Childhood Healthy Lifestyle Program (i-MaCHeL), Control Group: Standard health education
- Where
- Malaysia
- Volunteers
- 460 people, healthy volunteers welcome
- Sponsor
- Universiti Sultan Zainal Abidin
Childhood Obesity Prevention
Anthropometric Outcomes of a Mobile Health Intervention for Eating Behaviour and Lifestyle in Infancy
Lifestyle, activity, and feeding behaviours during early childhood set the foundation for subsequent lifelong metabolic health as an adult.
- Trial name
- NCT06457750
- Testing
- Feeding, Lifestyle, Activity Goals (FLAGs) Digital Health Application
- Where
- Singapore
- Volunteers
- 440 people, healthy volunteers welcome
- Sponsor
- KK Women's and Children's Hospital
Primary Prevention
Prevention Program Promoting Self Resilience, Positive Self-Image and Body Image Among Adolescents
The study is a group randomized controlled trial. High school classes were allocated by randomization to the intervention or control group by a Randomization function in Excel computer program.
- Trial name
- NCT03216018
- Testing
- Prevention program: "In Favor of Resilient Self"
- Where
- Israel
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Tel Hai College
Hernia
Peristomal Mesh for Prophylaxis of Parastomal Hernia
The study aims to prove differences or equalities in outcome for patients operated with or without a peristomal mesh in the sublay position when establishing a permanent colostomy.
- Trial name
- NCT00496418
- Testing
- Mesh in permanent colostomy
- Where
- Norway
- Volunteers
- 60 people
- Sponsor
- Oslo University Hospital
Congenital Heart Disease, Health Related Physical Fitness
Web-based Motor Intervention to Increase Health Related Physical Fitness in Children With Congenital Heart Disease
Children with congenital heart diseases (CHD) often show reduced health related physical fitness as well as limitations in gross and fine motor skills/development.
- Conditions
- Congenital Heart Disease, Health Related Physical Fitness, Motor Skills, Cardiovascular Prevention
- Trial name
- NCT03488797
- Testing
- Supervised web- and home-based exercise intervention
- Where
- Germany
- Volunteers
- 70 people
- Sponsor
- Deutsches Herzzentrum Muenchen
Obesity, Activity, Motor
Healthy Juntos Pilot Study
The purpose of the study is to assess the feasibility, acceptability, and preliminary effects of a digital (web and mobile phone-based) program to improve physical activity levels and quality dietary intake among Hispanic…
- Conditions
- Obesity, Activity, Motor, Diet, Healthy, Sedentary Behavior
- Trial name
- NCT03986190
- Testing
- Healthy Juntos
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Miami
Pediatric Obesity
Healthy Eating for My Infant (HEMI)
Infants from underserved and minority backgrounds are at increased risk for obesity and poor feeding and nutrition outcomes, but obesity prevention programs tailored specifically to the needs of these infants are lacking.
- Trial name
- NCT04977947
- Testing
- Healthy Eating for My Infant
- Where
- 2 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Cincinnati
Behavior and Behavior Mechanisms
Families Talking Together Plus: An Approach to Promote Sexual Delay and Strengthen Sexual Risk Avoidance Education
Despite reductions in adolescent sexual behavior over the past decade, premature sexual activity remains prevalent among adolescents and alarming adolescent sexual and reproductive health (SRH) disparities exist.
- Trial name
- FTT+ (NCT04731649)
- Testing
- Families Talking Together Plus (FTT +)
- Where
- United States
- Volunteers
- 1,227 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Suicide Prevention
Integrating the Youth Nominated Support Team (YST) With CBT for Black Youth With Acute Suicide Risk
The investigators are modifying and testing the preliminary effectiveness and implementation of the combination of two psychosocial interventions, Cognitive Behavioral Therapy for Suicide Prevention (CBT-SP) and the…
- Trial name
- NCT06941311
- Testing
- Cognitive Behavioral Therapy for Suicide Prevention (CBT-SP), Youth-Nominated Support Team
- Where
- 2 sites in United States
- Volunteers
- 26 people
- Sponsor
- University of Michigan
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