Clinical trials: Prospective
Type 1 Diabetes
Threshold Suspend in Pediatrics at Home
The study objective is to demonstrate that home use of Threshold Suspend (TS) is not associated with glycemic deterioration in pediatric patients with type 1 diabetes, as measured by change in A1C.
- Trial name
- NCT02120794
- Testing
- 530G Insulin pump
- Where
- 16 sites in United States
- Volunteers
- 194 people
- Sponsor
- Medtronic MiniMed, Inc.
Renal Insufficiency, Acute
Determination of the "Tissue Transit Time" (TTT)
Determination of Tissue Transit Time (TTT) as a parameter with high prognostic value to predict the functional course of the differential renal function and the development of the differential renal function after pyeloplasty
- Trial name
- NCT03311256
- Testing
- Tissue Transit Time
- Where
- 9 sites in Germany, Switzerland
- Volunteers
- 119 people
- Sponsor
- University Hospital Tuebingen
Attention-Deficit, Hyperactivity Disorder
Diagnostic Accuracy and Safety of the Attention-Deficit/Hyperactivity Disorder Auxiliary Evaluation System (AHEF) in Chinese Children Aged 6 to 12
This clinical trial aims to evaluate the diagnostic efficacy and safety of the Attention Deficit Hyperactivity Disorder Assessment System (AHEF) in children aged 6 to 12 in China, while ensuring the safety of the subjects and…
- Trial name
- NCT07683156
- Testing
- AHEF
- Where
- 8 sites in China
- Volunteers
- 570 people, healthy volunteers welcome
- Sponsor
- Chongqing Jinsaixing Medical Technology Co., Ltd
COVID
COVID-19 Registry Rhineland-Palatinate (Germany)
Documentation of all patients undergoing inpatient treatment for SARS-CoV-2 infection with regard to clinical status at admission, medical history, inpatient treatment and course of disease.
- Trial name
- NCT04335188
- Testing
- Prospective oberservational registry
- Where
- Germany
- Volunteers
- 2,589 people
- Sponsor
- IHF GmbH - Institut für Herzinfarktforschung
Acne Vulgaris
A Double Blinded, Prospective, Randomized, Vehicle Controlled Multi-center Study of Photodynamic Therapy With Visonac® Cream in Patients With Acne Vulgaris
This study is intended to evaluate the efficacy and safety of Visonac Photodynamic Therapy (PDT) in patients with severe acne, score 4 on global IGA scale.
- Trial name
- NCT01347879
- Testing
- Visonac PDT, Vehicle cream with PDT
- Where
- 15 sites in United States
- Volunteers
- 153 people
- Sponsor
- Photocure
Peripherally Inserted Central Catheter, Umbilical Venous Catheter
Umbilical Venous Versus Peripherally Inserted Central Catheters in Neonates: A Prospective Cohort Study of Complications, Catheter Survival, and CLABSI"
This study aims to prospectively compare umbilical venous catheters (UVCs) and peripherally inserted central catheters (PICCs) in neonates, focusing on complications, catheter survival, and central line-associated bloodstream…
- Conditions
- Peripherally Inserted Central Catheter, Umbilical Venous Catheter, CLABSI - Central Line Associated Bloodstream Infection
- Trial name
- NCT07209670
- Testing
- peripherally inserted central catheter insertion, umbilical venous catheters insertion
- Volunteers
- 360 people
- Sponsor
- Assiut University
Multidrug Resistant Organisms, Healthcare Associated Infections
Effectiveness of Enhanced Terminal Room Disinfection to Prevent Healthcare-associated Infections (HAIs)
Enhanced terminal room disinfection is a novel, promising, but still unproven strategy for the prevention of healthcare-associated infections (HAIs) due to selected multidrug-resistant (MDR) bacterial pathogens.
- Trial name
- NCT01579370
- Testing
- Quaternary ammonium, Bleach, Quaternary ammonium and UV-C light
- Where
- 9 sites in United States
- Volunteers
- 21,395 people
- Sponsor
- Duke University
Chronic Pancreatitis
Treatment Strategy of Pancreatic Radiolucent Stone
Treatment strategy of chronic pancreatitis (CP) patients with large pancreatic radiolucent stone (≥ 5mm) has not been established.
- Trial name
- NCT04628273
- Testing
- encoscopic retrograde cholangio-pancreatography, extracorporeal shock wave lithotripsy
- Volunteers
- 52 people
- Sponsor
- Changhai Hospital
Peripheral Nerve Injuries
Prospective Comparison of Adductor Canal Block Performed With a Multiport Versus Single Bevel Needle
Early ambulation after knee replacement surgery is made possible in large part by providing safe and effective pain control. Peripheral nerve blocks are increasingly used for postoperative analgesia since they can provide…
- Trial name
- NCT02786888
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Utah
Keloid
Evaluation of the Initial Safety and Efficacy of Keloid Lesions Treated With MF-4181
The objective of the study is to evaluate the initial safety and efficacy of MF-4181, a hydrogel scaffold, in the reduction of the volume, appearance, and/or symptoms associated with keloid scarring in subjects undergoing…
- Trial name
- NCT01446770
- Testing
- Hydrogel scaffold (MF-4181)
- Where
- The Bahamas
- Volunteers
- 19 people
- Sponsor
- Halscion, Inc.
Myelofibrosis (MF), Polycythemia Vera
MPNdpoint. Single-center, Retrospective, Prospective Study of the Outcome of Patients With Philadelphia-negative Chronic Myeloproliferative Neoplasms
Chronic myeloproliferative neoplasms (MPNs) are hematologic disorders of the myeloid lineage characterized by clonal proliferation of hematopoietic stem cells, high risk of thrombotic-hemorrhagic complications, and transformation…
- Conditions
- Myelofibrosis (MF), Polycythemia Vera, Essential Thrombocythaemia
- Trial name
- NCT07863466
- Where
- Italy
- Volunteers
- 1,190 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Gastric Ultrasonography, Supraglottic Airways
Comparison of Gastric Volume Changes After Ventilation With Endotracheal Tube, First-Generation Supraglottic Airway, and Second-Generation Supraglottic Airway in Pediatric Patients
This study aims to compare the gastric volumes of pediatric patients undergoing positive-pressure ventilation with different airway management techniques.
- Conditions
- Gastric Ultrasonography, Supraglottic Airways, Supraglottic Airway Use in Children, Gastric Volume
- Trial name
- NCT07555080
- Where
- Turkey (Türkiye)
- Volunteers
- 250 people
- Sponsor
- Istanbul University
Spine Deformity
Perioperative Nutritional Status and Nutritional Support in Patients With Spinal Deformity
To investigate the nutritional status, nutritional support and postoperative complications of patients undergoing spinal orthopedic surgery during the perioperative period.
- Trial name
- NCT04968483
- Testing
- Data collection
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Peking University Third Hospital
Pediatric Anesthesia
Variation of Cerebral Blood Flow in Anterior Cerebral and Basilar Artery in Neonates and Infants in Genreal Anesthesia With Caudal Block
With this study we want to see how the blood flow in the anterior cerebral artery (ACA) and the basilar artery (BA) after the caudal block changes.
- Trial name
- NCT02761954
- Volunteers
- 50 people
- Sponsor
- Bürgerhospital Frankfurt
Acute Lymphoblastic Leukemia
GIMEMA LAL 0496: High-dose Anthracycline in the Induction Regimen for the Treatment of Adult ALL.
The present study aims at verifying the state of the art in what this illness concerns and at organizing a centralized samples analysis.
- Trial name
- NCT00439920
- Testing
- High-dose anthracycline
- Sponsor
- Gruppo Italiano Malattie EMatologiche dell'Adulto
COVID-19 Pandemic
COVID-19 Molecular OTC At Home Test
The objective of this study is to evaluate the a molecular, OTC/At-Home COVID-19 Test in individuals presenting at a medical facility.
- Trial name
- NCT05704803
- Testing
- Diagnostic Test: IN Vitro
- Where
- 4 sites in United States
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- 3EO Health
Chronic Graft-Versus-Host Disease, Graft vs Host Disease
A Prospective Study of Madecassoside Tablets in Sclerotic Chronic Graft-versus-Host Disease After Allo-HSCT
Sclerotic chronic graft-versus-host disease (scl-cGVHD) is a severe subtype of chronic GVHD after allogeneic hematopoietic stem cell transplantation (allo-HSCT), characterized by skin sclerosis, fascial involvement, and…
- Trial name
- NCT07606703
- Testing
- Madecassoside Tablets, Standard Therapy
- Where
- China
- Volunteers
- 30 people
- Sponsor
- WeiShi
Congenital Hydronephrosis, UTD Grading System
Natural Course of Congenital Hydronephrosis in Infants Aged 0-6 Months
This project aims to systematically delineate the natural progression of congenital hydronephrosis diagnosed within the critical window of 0-6 months through a prospective, multicenter, observational cohort study.
- Conditions
- Congenital Hydronephrosis, UTD Grading System, Natural Progression, Pediatric
- Trial name
- NCT07382570
- Testing
- No Intervention: Observational Cohort
- Where
- China
- Volunteers
- 330 people
- Sponsor
- The Children's Hospital of Zhejiang University School of Medicine
Crohn Disease
Pre-stenotic Inflammation Following Endoscopic Balloon Dilatation in Crohn's Disease: A Prospective Study
As a consequence of chronic relapsing inflammation in Crohn's disease (CD), progressive bowel damage and scarring occurs in affected regions of intestine.
- Trial name
- NCT04803916
- Where
- Israel
- Volunteers
- 24 people
- Sponsor
- Shaare Zedek Medical Center
Foreign Bodies, Tumor
The Effects of High-flow Nasal Oxygen on Oxygenation During Rigid Bronchoscopy Under General Anesthesia in Pediatric Patients
The aim of this study is to evaluate the effect of high-flow nasal cannula oxygen administration on maintenance of oxygenation and removal of carbon dioxide during apnoeic period in pediatric patients undergoing general…
- Conditions
- Foreign Bodies, Tumor, Stenosis of Trachea, Bronchus
- Trial name
- NCT03905733
- Testing
- Optiflow
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Yonsei University
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