Clinical trials: Prostate
Prostate Cancer
Safety and Efficacy of Irreversible Electroporation in Ablation of Prostate Cancer in Humans
Up to 16 patients with confirmed low- or intermediate risk prostate cancer scheduled for a radical prostatectomy will be asked to have the Irreversible Electroporation (IRE) procedure approximately 30 days prior to the…
- Trial name
- NCT01790451
- Testing
- Irreversible Electroporation
- Where
- Netherlands
- Volunteers
- 16 people
- Sponsor
- Clinical Research Office of the Endourological Society
Prostate Hyperplasia, Surgery
Comparison Between Bipolar Transurethral Resection of the Prostate and Moses Assisted Holmium Laser Enucleation of the Prostate
Introduction: Multiple studies have demonstrated the superiority of HoLEP in aspects such as transfusión rates or postoperative stay.
- Conditions
- Prostate Hyperplasia, Surgery, Endoscopic Anatomical Enucleation of the Prostate (EEAP)
- Trial name
- NCT06649357
- Testing
- MoLEP, BiTURP
- Where
- 6 sites in Spain
- Volunteers
- 130 people
- Sponsor
- Fundacio Puigvert
Breast Cancer, Insulin Resistance
Alternative Physical Activity Strategies for Breast Cancer Survivors
The primary aim of this study is to compare the acute glycemic effects of two novel, alternative physical activity (PA) strategies (dispersed post-meal PA, PA snacks) to a no PA condition and to exercise sessions representing the…
- Conditions
- Breast Cancer, Insulin Resistance, Cardiometabolic Risk Factors
- Trial name
- PACE (NCT06633380)
- Testing
- Standard Physical Activity - Fasted, Standard Physical Activity - Post-Meal, Dispersed Physical Activity
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Metastatic Castration-resistant Prostate Cancer (mCRPC)
Descriptive Analysis of Clinical Outcomes in Patients With Prostate Gland Cancer, Which Spreads to Other Parts of the Body, Who Were Treated First With Novel Anti-hormone Therapy Followed by a Second Line Treatment With Novel Anti-Hormone Therapy or RadIum-223 (Xofigo).
In this study researcher want to learn more about the overall survival in patients suffering from prostate gland cancer which spread outside the prostate to other parts of the body who received either a novel anti-hormone therapy…
- Trial name
- PHENIX (NCT03896984)
- Testing
- Radium-223 (Xofigo, BAY88-8223), Abiraterone, Enzalutamide
- Where
- United States
- Volunteers
- 346 people
- Sponsor
- Bayer
Metastatic Prostate Carcinoma, Prostate Carcinoma Metastatic in the Bone
Fluciclovine F18 PET/CT Imaging in Assessing Hormone-Naive Men With Prostate Cancer That Has Spread to the Bone
This trial studies how well fluciclovine 18F PET/CT imaging works in assessing hormone-naive men with prostate cancer that has spread to the bone. Fluciclovine 18F is a radioactive drug used to measure tumor growth.
- Conditions
- Metastatic Prostate Carcinoma, Prostate Carcinoma Metastatic in the Bone, Stage IV Prostate Cancer
- Trial name
- NCT03707184
- Testing
- Computed Tomography, Fluciclovine F18, Positron Emission Tomography
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- University of Utah
Lung Ultrasound Score, Transurethral Resection (TUR) Syndrome
Lung Ultrasound Versus Inferior Vena Cava Collapsibility Index for Early Prediction of Volume Overload During Transurethral Resection of Prostate
The aim of this study is to compare between accuracy of lung US and IVC CI for early prediction of volume overload during TURP. Primary outcome: The incidence of volume overload during transurethral resection of prostate.
- Conditions
- Lung Ultrasound Score, Transurethral Resection (TUR) Syndrome, Prostate
- Trial name
- NCT07164638
- Testing
- lung ultrasound (LUS), IVC collapsibility index
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Tanta University
Prostate Cancer
Systemic Therapy in Advancing or Metastatic Prostate Cancer: Evaluation of Drug Efficacy
The overall aim of this trial, which is called STAMPEDE, is to assess novel approaches for the treatment of men with prostate cancer who are starting long-term ADT for the first time, termed hormone-naïve prostate cancer.
- Trial name
- STAMPEDE (NCT00268476)
- Testing
- Celecoxib, Docetaxel, Prednisolone
- Where
- 120 sites in Switzerland, United Kingdom
- Volunteers
- 11,992 people
- Sponsor
- Medical Research Council
Prostate Cancer
Calcitriol and Dexamethasone in Treating Patients With Prostate Cancer That Did Not Respond to Hormone Therapy
RATIONALE: Calcitriol may help prostate cancer cells become more like normal cells, and to grow and spread more slowly. Dexamethasone may help calcitriol work better by making tumor cells more sensitive to the drug.
- Trial name
- NCT00524589
- Testing
- calcitriol, dexamethasone, protein expression analysis
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Roswell Park Cancer Institute
Prostate Cancer
Biological Imaging for Optimising Clinical Target Volume (CTV) and Gross Tumour Volume (GTV) Contouring in Prostate Cancer to Improve the Possibilities for Intensity Modulated RadioTherapy (IMRT) Dose Escalation
The clinical outcome after external beam irradiation for prostate cancer is disappointing in the advanced tumor stages. There are indications that an increase in radiation dose to the tumor will improve outcome significantly…
- Trial name
- NCT00122252
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Alberta Health services
Hematuria, Hematospermia
The Use of Finasteride to Reduce Hematuria and Hematospermia Following TRUS Prostate Biopsy
The purpose of our study is primarily to evaluate the effects of 5mg finasteride on hematuria and hematospermia commonly associated with prostate biopsies.
- Trial name
- NCT00600691
- Testing
- Finasteride
- Where
- 2 sites in Canada
- Volunteers
- 29 people
- Sponsor
- University of British Columbia
Stage IV Prostate Cancer, Stage IV Colon Cancer
Dibenzyl Trisulphide (GUINEAHEN WEED) for Stage IV Cancer
This study is being done to find the effect of Dibenzyl Trisulphide (active ingredient in Guinea Hen Weed in combination in patients with stage four cancer of the breast, prostate, cervix and colon.
- Conditions
- Stage IV Prostate Cancer, Stage IV Colon Cancer, Stage IV Breast Cancer, Stage IV Cancer of the Cervix
- Trial name
- NCT04113096
- Testing
- Dibenzyl trisulphide capsules
- Where
- Jamaica
- Volunteers
- 104 people
- Sponsor
- The University of The West Indies
Prostate Cancer
Immuno-molecular Approaches for Non-invasive Diagnosis of Prostate Cancer
The purpose of this study is to isolate and characterize tumor cells non-invasively from biological samples in patients with prostate cancer and demonstrate the ability to identify the presence and number of tumor cells before…
- Trial name
- PROSTA-PAP (NCT04702633)
- Testing
- Results obtained by biopsy and MRI results., Clinical data
- Where
- France
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Prostate Cancer, Gleason Score
Dual-tracer PET Radiomics for Prostate Cancer Stratification
This single-center retrospective study aims to develop an interpretable radiomics model based on dual-tracer PET/CT to preoperatively predict the postoperative pathological Gleason grade group in treatment-naïve prostate cancer…
- Conditions
- Prostate Cancer, Gleason Score, PET/CT, Radiomics
- Trial name
- NCT07655648
- Testing
- PET/CT with Gallium-68 labeled PSMA and RM26
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Xiangya Hospital of Central South University
Adenocarcinoma of Prostate, Adenocarcinoma of the Prostate Stage I
Treatment Decision Analysis Model for Prostate Cancer: A Randomized Trial
This is a psychosocial/behavioral study and does not involve administration of any treatment or diagnostic procedures. We will use a randomized trial to test the hypothesis that a decision analysis model that provides…
- Conditions
- Adenocarcinoma of Prostate, Adenocarcinoma of the Prostate Stage I, Adenocarcinoma of the Prostate Stage II, Adenocarcinoma of the Prostate Stage III
- Trial name
- NCT02024685
- Testing
- Personalized Treatment Recommendations, Standard patient-physician counseling interaction
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- Case Comprehensive Cancer Center
Prostate Cancer
CT Scans in Guiding the Treatment of Patients With Prostate Cancer Who Are Undergoing Radiation Therapy
RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Multiple CT scans may improve the accuracy of radiation therapy for prostate cancer.
- Trial name
- NCT00020891
- Testing
- computed tomography, radiation therapy
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Advanced Solid Tumor, Advanced Malignant Neoplasm
The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)
The Phase 2 monotherapy portion of this study is currently enrolling and will evaluate the efficacy and safety of PC14586 (INN rezatapopt) in participants with locally advanced or metastatic solid tumors harboring a TP53 Y220C…
- Conditions
- Advanced Solid Tumor, Advanced Malignant Neoplasm, Metastatic Cancer, Metastatic Solid Tumor
- Trial name
- NCT04585750
- Testing
- rezatapopt, pembrolizumab
- Where
- 76 sites in United States, Australia and 7 more
- Volunteers
- 300 people
- Sponsor
- PMV Pharmaceuticals, Inc
Breast Neoplasms, Ovarian Neoplasms
Ascertainment of Peripheral Blood or Saliva Samples for Genetic Epidemiology Studies of Familial Cancers
The purpose of this study is to better understand the genetic causes of cancer and the inherited tendency to develop cancer. To accomplish this, blood specimens and/or saliva samples and/or tumor and normal tissue blocks from…
- Conditions
- Breast Neoplasms, Ovarian Neoplasms, Colonic Neoplasms, Prostatic Neoplasms
- Trial name
- NCT00579163
- Where
- United States
- Volunteers
- 992 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Postoperative or Postradiation Adjuvant Androgen Deprivation Therapy in Locally Advanced Prostate Cancer (High and Very High Risk) Patients
Non-Interventional Study PREVENT
This is a multicentre, non-interventional, prospective study to be carried out in representative medical institutions in order to get the information on administration of postoperative and post-radiation adjuvant androgen…
- Trial name
- PREVENT (NCT02155998)
- Where
- 14 sites in Russia
- Volunteers
- 200 people
- Sponsor
- AstraZeneca
Prostate Cancer
Non-significant Risk (NSR) Study of [68Ga]-PSMA-11 (Illuccix) as a BgRT BioGuide on RefleXion X1
To qualitatively determine the imaging performance of PET-CT imaging subsystem of the RefleXion X1 System Device in patients undergoing standard-of-care (SOC) [68Ga]-PSMA-11 PET-CT using Illuccix on the same day.
- Trial name
- NCT06353321
- Testing
- PET-CT imaging subsystem of the RefleXion X1 System Device
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Texas Southwestern Medical Center
Prostate Cancer
Primary Prostatic Lymphoma on a 66 Year-old Male in Mexico.
A 66-year-old male known case of diabetes and hypertension presented to the urology clinic with a 2-month history of lower urinary tract symptoms (LUTS), particularly poor flow, sense of incomplete bladder emptying, dysuria and…
- Trial name
- NCT07134504
- Where
- Mexico
- Volunteers
- 1 people
- Sponsor
- Instituto Mexicano del Seguro Social