Clinical trials: Prostate Neoplasm
Prostatic Cancer
Prostate Cancer Risk in Firefighters
Firefighters have been shown to be at increased risk for various types of cancer, including prostate cancer. This study will try to explore possible reasons for this increase in risk.
- Trial name
- NCT03893123
- Testing
- Observational study, prostate cancer is outcome of interest
- Where
- Norway
- Volunteers
- 4,500 people
- Sponsor
- Oslo University Hospital
Prostate Cancer
Heterogeneity of Tertiary Lymphoid Structures Predicts Distinct Malignancy and Immune Microenvironment in Prostate Cancer: a Retrospective Cohort Study
The aim of this study was to reveal the predictive value of spatial heterogeneity and maturity difference of tertiary lymphoid structure in pathological sections of prostate cancer patients for clinical features and prognosis.
- Trial name
- NCT06484127
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Fudan University
Biochemically Recurrent Prostate Carcinoma, Prostate Adenocarcinoma
An Investigational Scan (rhPSMA-7.3 PET/CT) for Detecting Biochemically Recurrent Prostate Cancer, ENLIGHTEN Trial
This phase II trial evaluates an imaging technique (rhPSMA-7.3 positron emission tomography [PET]/computed tomography [CT]) for detecting prostate cancer in patients who have increasing prostate-specific antigen levels following…
- Trial name
- NCT06813898
- Testing
- Computed Tomography, Electronic Health Record Review, Flotufolastat F-18 Gallium
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Northwestern University
Prostate Cancer
Evaluation of the Safety and Efficacy of the BioProtect Balloon in Prostate Cancer Subjects Undergoing Radiotherapy
Primary Goal The study's primary goal is to assess the safety of the BioProtect biodegradable balloon implant and implantation procedure, in prostate cancer subjects undergoing routine XRT treatment.
- Trial name
- NCT00462124
- Testing
- Absorbable perirectal spacer
- Where
- Israel
- Volunteers
- 7 people
- Sponsor
- BioProtect
Prostate Cancer
Post-operative or Early Salvage XRT and ADT for High Risk PCa
RATIONALE: Conformal radiation therapy uses a 3-dimensional (3-D) image of the tumor to help focus thin beams of radiation directly on the tumor.
- Trial name
- NCT00949962
- Testing
- antiandrogen therapy, leuprolide acetate, 3-dimensional conformal radiation therapy
- Where
- France
- Volunteers
- 87 people
- Sponsor
- European Organisation for Research and Treatment of Cancer - EORTC
Prostate Cancer
Evaluation of a Blood Biomarker to Try and Distinguish Between the Presence or Absence of Aggressive Prostate Cancer
A Laboratory Study to Evaluate Urine and Blood Biomarkers That Can Distinguish Between the Presence or Absence of Aggressive Prostate Cancer
- Trial name
- NCT03256630
- Where
- United States
- Volunteers
- 128 people
- Sponsor
- Genomic Health®, Inc.
Prostate Cancer, Active Surveillance for Prostate Cancer
Stockholm3 Test Validation in Men on Active Surveillance in Switzerland (CHAS3 Trial)
The CHAS3 trial studies whether the Stockholm3 blood test can reliably detect if prostate cancer becomes more aggressive in men who are being carefully monitored instead of treated right away (active surveillance).
- Trial name
- CHAS3 (NCT07478536)
- Testing
- Stockholm3
- Where
- Switzerland
- Volunteers
- 350 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Prostate Cancer
Multifunctional Magnetic Resonance (MR) for Radiotherapy Planning in Prostate Cancer
To determine if functional MRI methods will aid planning of a radiation dose boost within the prostate in patients with prostate cancer potentially improving safety and efficacy.
- Trial name
- NCT01006564
- Testing
- Imaging Investigations (not radiation), Other
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Royal Marsden NHS Foundation Trust
B-cell Lymphoma, Chronic Lymphocytic Leukemia
Long-Term Follow-Up of AvenCell Sponsored CAR-T Cell Clinical Trials
The goal of this clinical study is to learn more about the long-term safety, effectiveness and prolonged action of patients who participated in an AvenCell-sponsored clinical trial and received treatment with AvenCell's UniCAR or…
- Conditions
- B-cell Lymphoma, Chronic Lymphocytic Leukemia, Hematologic Malignancy, AML (Acute Myelogenous Leukemia)
- Trial name
- PERSIST (NCT07474051)
- Testing
- UniCAR02-T (IMP) With Targeting Module TM123, UniCAR02-T-pPSMA, Allo-RevCAR01- T with Targeting Module R-TM123
- Where
- 5 sites in Germany
- Volunteers
- 178 people
- Sponsor
- AvenCell Therapeutics, Inc.
Prostate Cancer (Adenocarcinoma), Prostate Cancer Metastatic Disease
Osteosclerotic Changes on CT Predict Survival in Prostate Cancer
The study specifically investigated PC patients with bone metastasis and conducted a comprehensive analysis of the correlation between OCs and patient survival outcomes.
- Trial name
- NCT06883474
- Testing
- Osteosclerotic Changes on Computed Tomography
- Volunteers
- 211 people
- Sponsor
- Sun Yat-sen University
Prostate Cancer (Adenocarcinoma), Prostatic Neoplams
ProsBiT: Turkish Prostate Biopsy Study
ProsBiT is a prospective multicenter observational cohort study that collects standardized data on men undergoing prostate biopsy for suspected prostate cancer at 24 urology centers in Turkey.
- Conditions
- Prostate Cancer (Adenocarcinoma), Prostatic Neoplams, Prostate Specific Antigen
- Trial name
- ProsBiT (NCT07919379)
- Where
- Turkey (Türkiye)
- Volunteers
- 8,310 people
- Sponsor
- Istanbul Medeniyet University
Prostate Cancer
ClariCore System Used in Transperineal Prostate Biopsy
The overall objective of this study is to acquire ultrasound images, spectral data and prostate tissue biopsy cores using the ClariCore System via a transperineal approach.
- Trial name
- NCT03734575
- Testing
- ClariCore System
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- Precision Biopsy, Inc.
Ovarian Cancer, Prostate Cancer
Drug Intensive Monitoring Study of Olaparib in Clinical Practice Among Chinese Patients
This is a multi-centre, prospective, non-interventional study. The study will enrol about 860 Chinese cancer patients from around 56 sites.
- Trial name
- NCT04560452
- Where
- 37 sites in China
- Volunteers
- 1,018 people
- Sponsor
- AstraZeneca
Prostate Cancer
Magnetic Nanoparticle Thermoablation-Retention and Maintenance in the Prostate:A Phase 0 Study in Men
Men with early prostate cancer face a number of options which lie at the extremes of care. On one hand, active surveillance involves monitoring the disease and on the other, immediate treatment involves surgery or radiotherapy.
- Trial name
- MAGNABLATE I (NCT02033447)
- Testing
- Magnetic Nanoparticle Injection
- Where
- United Kingdom
- Volunteers
- 12 people
- Sponsor
- University College London Hospitals
Prostate Cancer Screening
Evaluation of An Online Intervention In Improving General Practitioners' Practice In Prostate Cancer Screening
The incidence of prostate cancer has been rising steadily both globally and in Malaysia. Besides an ageing population, another reason cited to explain the increase, is the corresponding increase in the prostate cancer screening…
- Trial name
- ProCaSS (NCT03633214)
- Testing
- Online training module
- Where
- Malaysia
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Carcinomas, Amyloidosis
B-Receptor Signaling in Cardiomyopathy
We hope to determine the importance of different genes (including B receptors) in anthracycline-induced cardiomyopathy. This has important benefits to patients exposed to anthracyclines, as this could help determine whether…
- Conditions
- Carcinomas, Amyloidosis, Anal Cancer, Anemia
- Trial name
- NCT01135849
- Where
- United States
- Volunteers
- 99 people
- Sponsor
- Daniel Bernstein
Radiation-induced Diarrhoea in Prostate and Rectal Cancer
Radiation-induced Diarrhoea During Curative EBRT of Prostate and Rectal Cancer
Approx. 80% of patients with prostate and rectal cancer who receive radiation therapy (RT) experience acute radiation-induced diarrhea (RID).
- Trial name
- PRECANU (NCT05684432)
- Testing
- No intervention
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- Aalborg University Hospital
Neoplastic Syndromes, Hereditary, Prostatic Neoplasms
Familial Prostate Cancer
The purpose of this study is to identify affected individuals in families with prostate cancer and to use this information to identify genetic markers closely-linked to the disease gene.
- Trial name
- NCT00001377
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- National Cancer Institute (NCI)
Prostate Cancer
Biopsy Study Comparing MRI and Ultrasound Soft Image Fusion Guided Biopsies and Gold Standard Prostate Biopsies.
Background: Prostate biopsies are usually performed due to accidentally discovered elevated prostate specific antigen (PSA) and/or abnormal digital rectal examination.
- Trial name
- NCT01455792
- Testing
- Biopsies using image fusion, Gold standard biopsy
- Where
- Norway
- Volunteers
- 200 people
- Sponsor
- Oslo University Hospital
Prostate Cancer
Trial of IV Injection of CV787 in Hormone Refractory Metastatic Prostate Cancer
This is a multi-center, open-label, dose finding study of CV787 adenovirus in patients with hormone refractory metastatic prostate cancer.
- Trial name
- NCT00116155
- Testing
- CV787 (CG7870)
- Sponsor
- Cell Genesys