Clinical trials: Prostatic Cancer
Health-Related Quality Of Life
A Pilot Study of Remote Monitoring to Improve Health Related Quality of Life of Men Following Prostate Cancer Treatment.
The purpose of this study is to determine the feasibility of using digital technology and remote monitoring to track health-related measures in men following prostate cancer treatment.
- Trial name
- NCT03434535
- Testing
- Technology Intervention
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Johns Hopkins University
Prostate Cancer
Nerve-Sparing Radical Prostatectomy With or Without Nerve Grafting Followed by Standard Therapy for Erectile Dysfunction in Treating Patients With Localized Prostate Cancer
RATIONALE: Nerve-sparing radical prostatectomy with nerve grafting followed by standard therapies for erectile dysfunction may be effective in helping patients with prostate cancer improve sexual satisfaction and quality of life.
- Trial name
- NCT00080808
- Testing
- Alprostadil (E1), Papaverine, Phentolamine mesylate
- Where
- United States
- Volunteers
- 111 people
- Sponsor
- M.D. Anderson Cancer Center
Prostate Cancer
Behavior-Based Dietary Intervention in Treating Patients With Hormone-Refractory Prostate Cancer
RATIONALE: A low-fat, high-fiber diet that includes soy protein may prevent disease progression in patients with hormone-refractory prostate cancer. Nutrition counseling may help motivate patients to follow this diet.
- Trial name
- NCT00082732
- Testing
- behavioral dietary intervention, dietary intervention, therapeutic dietary intervention
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- M.D. Anderson Cancer Center
Prostate Cancer (Adenocarcinoma), Prostate Cancer Metastatic Disease
Osteosclerotic Changes on CT Predict Survival in Prostate Cancer
The study specifically investigated PC patients with bone metastasis and conducted a comprehensive analysis of the correlation between OCs and patient survival outcomes.
- Trial name
- NCT06883474
- Testing
- Osteosclerotic Changes on Computed Tomography
- Volunteers
- 211 people
- Sponsor
- Sun Yat-sen University
Prostate Cancer
Prevalence of Neglected Side Effects to Radical Prostatectomy
The purpose of this exploratory data collection is to strengthen our knowledge of some of the rarer distresses following surgical removal of the prostate.
- Trial name
- NCT01742962
- Testing
- Radical prostatectomy for prostate cancer
- Where
- Denmark
- Volunteers
- 396 people
- Sponsor
- Copenhagen University Hospital at Herlev
Advanced Prostate Cancer
A Study of Neoadjuvant Hormone Therapy in Patient With Advanced Prostate Cancer Undergoing Radical Prostatectomy.
This is A Multi-centre, Single-arm, Prospective, Interventional Study to Assess Efficacy and Safety of Neoadjuvant Hormone Therapy using Zoladex (Goserelin) and Casodex (Bicalutamide) in Patients with Advanced Prostate Cancer…
- Trial name
- NCT03971110
- Testing
- Zoladex and Casodex
- Where
- 15 sites in China
- Volunteers
- 9 people
- Sponsor
- AstraZeneca
Prostate Cancer Detection
Zinc/PSA Ratio as a Novel Biomarker for Prostate Cancer Detection
Although Prostate Specific Antigen (PSA) is a useful marker for early detection of the prostate cancer, its specivity is not sufficient.
- Trial name
- NCT02013180
- Where
- Turkey (Türkiye)
- Volunteers
- 480 people
- Sponsor
- Bagcilar Training and Research Hospital
Prostatic Neoplasms, Quality of Life
Impact on Quality of Life 3 Years After Diagnosis of Prostate Cancer
To study the quality of life of patients with prostate cancer at a distance from their care at a time when they are supposed to have taken a "normal" life and compared to subjects without cancer prostate of the same age.
- Trial name
- EPICAP-QALY (NCT02854982)
- Testing
- therapeutic management of the prostate Cancer as usual
- Where
- France
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Prostate Biopsy, Antibiotic
Transperineal MRI-TRUS Fusion Guided Prostate Biopsy With vs Without Antibiotic Prophylaxis
Prostate biopsy is indicated in patients with suspected prostate cancer and has been traditionally performed through the rectum using antibiotic prophylaxis.
- Trial name
- NORAPP (NCT04146142)
- Testing
- Transperineal prostate biopsy with or without antibiotic prophylaxis
- Where
- 2 sites in Germany, Norway
- Volunteers
- 550 people
- Sponsor
- Oslo University Hospital
Prostate Cancer
Angelica Sinensis for the Treatment of Hot Flashes in Men Undergoing LHRH Therapy for Prostate Cancer
Men undergoing androgen deprivation therapy for prostate cancer may experience significant side effects including symptoms of intense heat, facial flushing, and sweating.
- Trial name
- NCT00199485
- Testing
- Angelica Sinensis
- Where
- Canada
- Volunteers
- 44 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Prostate Cancer
External Beam Radiation Therapy (EBRT) With or Without Hormonal Therapy in Prostate Cancer
Primary Objective: To assess the possible improvement in prostate specific antigen (PSA) outcome of short course androgen suppression therapy in conjunction with dose-escalation intensity modulated radiation therapy (IMRT), 3D…
- Trial name
- NCT00388804
- Testing
- Radiation Therapy, Bicalutamide, Leuprolide
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- M.D. Anderson Cancer Center
Metastatic Prostate Carcinoma
Value of FLT PET/CT in Radium-223 Therapy of mCRPC Patients
The aim of the study is to investigate whether positron emission tomography (PET) using the tracer 18F-Fluorothymidine (FLT) can provide information on proliferative activity in bone marrow of patients receiving Radium 223…
- Trial name
- NCT03011749
- Testing
- FLT PET/CT
- Where
- Denmark
- Volunteers
- 6 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Prostate Cancer, Active Surveillance for Prostate Cancer
Stockholm3 Test Validation in Men on Active Surveillance in Switzerland (CHAS3 Trial)
The CHAS3 trial studies whether the Stockholm3 blood test can reliably detect if prostate cancer becomes more aggressive in men who are being carefully monitored instead of treated right away (active surveillance).
- Trial name
- CHAS3 (NCT07478536)
- Testing
- Stockholm3
- Where
- Switzerland
- Volunteers
- 350 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Prostate Cancer
Surgery in Treating Patients With Prostate Cancer
RATIONALE: Prostatectomy may be an effective treatment for prostate cancer that has not responded to radiation therapy. PURPOSE: This phase II trial is studying how well prostatectomy works in treating patients with recurrent or…
- Trial name
- NCT00002938
- Testing
- conventional surgery
- Where
- 61 sites in United States
- Volunteers
- 49 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Prostate Cancer
Effects of PEEP on Intracranial and Intraocular Pressure in Robot-assisted Laparoscopic Radical Prostatectomy
To investigate the effects of positive end-expiratory pressure (PEEP) on the intracerebral pressure (ICP) and intraocular pressure (IOP) in patients undergoing robot assisted laparoscopic radical prostatectomy (RALRP)
- Trial name
- NCT03031613
- Testing
- PEEP group, ZEEP group
- Where
- South Korea
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Gangnam Severance Hospital
Hot Flashes, Prostate Carcinoma
Vitamin B6 in Reducing Hot Flashes in Participants With Prostate Cancer Undergoing Antiandrogen Therapy
This pilot phase II trial studies how well vitamin B6 works in reducing hot flashes in participants with prostate cancer undergoing antiandrogen therapy.
- Trial name
- NCT03580499
- Testing
- Vitamin B6, Questionnaire Administration
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University
Prostate Cancer
Magnetic Nanoparticle Thermoablation-Retention and Maintenance in the Prostate:A Phase 0 Study in Men
Men with early prostate cancer face a number of options which lie at the extremes of care. On one hand, active surveillance involves monitoring the disease and on the other, immediate treatment involves surgery or radiotherapy.
- Trial name
- MAGNABLATE I (NCT02033447)
- Testing
- Magnetic Nanoparticle Injection
- Where
- United Kingdom
- Volunteers
- 12 people
- Sponsor
- University College London Hospitals
Prostatic Neoplasms
Adjuvant Radiation Therapy vs. Watchful Waiting Following Radical Prostatectomy in High Risk Prostate Cancer
The purpose of this study is to determine whether adjuvant radiotherapy following radical prostatectomy in prostate cancer patients with positive margins or capsular penetration improves biochemical, overall and/or cancer…
- Trial name
- NCT02668718
- Testing
- Adjuvant radiotherapy
- Volunteers
- 250 people
- Sponsor
- Helsinki University Central Hospital
Prostate Cancer
Sandostatin for Patients With Androgen Independent Prostate Cancer
This is an open label, single center Phase II trial of Sandostatin LAR in patients with hormone refractory prostate cancer. Patients will receive Sandostatin LAR 30 mg intramuscularly every 28 days.
- Trial name
- NCT00510224
- Testing
- Sandostatin
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- University of California, San Francisco
Prostate Cancer
Mitoxantrone and G-CSF in Treating Patients With Metastatic Prostate Cancer
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining chemotherapy with G-CSF may make tumor cells more sensitive to the chemotherapy drug and may kill…
- Trial name
- NCT00003183
- Testing
- filgrastim, mitoxantrone hydrochloride
- Where
- 2 sites in United States
- Volunteers
- 64 people
- Sponsor
- Hope Cancer Institute, Inc.