Clinical trials: Psychiatric Problem
Gender Dysphoria
Understanding Perceived Access and Receipt of Gender-affirming Treatments Among Transgender Veterans
Transgender Veterans (trans Vets) frequently experience gender dysphoria or distress related to discord between their gender identity and birth sex.
- Trial name
- NCT06615401
- Where
- United States
- Volunteers
- 986 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Mental Health
The Digital Wellbeing Project
This goal of this randomized control trial is to test whether a web application that provides sexual and gender minority youth ages 13-19 (N=200) with tools for affirming their identities and coping with minority stress can…
- Trial name
- NCT05061966
- Testing
- immi, Control
- Where
- United States
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Mental Well-being, Happiness
Joyful Parenting Pilot Project RCT Study
Aims: To enhance mental well-being of adolescents, adults and their families by creating a positive, happy and joyful environment in the community. Targets: Parents aged 12-59 and their family members in Hong Kong.
- Trial name
- NCT03282071
- Testing
- Joyful Parenting Intervention
- Where
- 2 sites in Hong Kong
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Mental Health
Evaluation of Implementing FLOW
Adequate access to mental health is one of the most important problems facing the VA and VISN 19. Mental health patients who are stabilized and recovered should be transitioned back to primary care to increase availability in…
- Trial name
- FLOW (NCT04193033)
- Testing
- FLOW intervention
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- VA Office of Research and Development
Gender Dysphoria, Adolescent
Counseling Among Gender Diverse Adolescents Who Use Depot Medroxyprogesterone
Recommendations regarding contraceptive counseling and reproductive health differ amongst transgender and gender diverse (TGD) youth compared to cis-gender youth.
- Trial name
- NCT05726903
- Testing
- Depo-subQ Provera Injectable Product
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Food Allergy in Children, Caregiver Burnout
The Psychosocial Outcomes in Caregivers of Children With Food Allergy
The purpose of this study is to evaluate use of a mobile application (also commonly referred to as an app) designed to support caregivers of children with newly diagnosed food allergy. This study has 2 phases.
- Conditions
- Food Allergy in Children, Caregiver Burnout, Psychosocial Problem, Family Research
- Trial name
- FASST (NCT04512924)
- Testing
- Enhanced mobile app with standard of care and education, Enhanced mobile app with standard of care, education and support resources
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Suicide, Surveillance
Southwest Hub for American Indian Youth Suicide Prevention Research
1. To use a SMART design to evaluate which of four sequences of New Hope (NH), Elders Resilience (ER) and Case Management (CM) have the greater effects on immediate and longer-term suicidal ideation (primary outcome) and…
- Conditions
- Suicide, Surveillance, Mental Health, Substance Use
- Trial name
- NCT03543865
- Testing
- New Hope (NH), Elders Resilience (ER), Case Management (CM)
- Where
- United States
- Volunteers
- 304 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Community Mental Health Services, Adolescent Well Being
Prevention and Early Identification for High Risk Youth in School-based Clinics
The proposed research project provides a novel approach to screening, early assessment, and preventive interventions for high-risk youth in racial/ethnic/linguistically (REL)-diverse communities.
- Conditions
- Community Mental Health Services, Adolescent Well Being, Resilience, Psychological, Health Equity
- Trial name
- NCT04935710
- Testing
- COPE2Thrive, Usual care
- Where
- 5 sites in United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Cambridge Health Alliance
Painful Digital Neuroma
Treatment of Painful Digital Neuroma Using A Pedicled Nerve Flap
Neuroma excision and digital nerve reconstruction remain the best option for the treatment of Painful Digital Neuroma (PDN). When the distal nerve end is preserved, conventional nonvascularized nerve grafting is the primary…
- Trial name
- NCT01684839
- Testing
- Pedicled nerve flap
- Where
- China
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- The Second Hospital of Tangshan
Covid19, Mental Health
Mental Health Among Patients, Providers, and Staff During the COVID-19 Era
The Mental Health Among Patients, Providers, and Staff (MHAPPS) Study is designed to study how the COVID-19 pandemic has affected mental health and wellbeing, and how to support mental health while minimizing the burden on the…
- Trial name
- MHAPPS (NCT04700137)
- Testing
- Caring Contacts Plus Introductory Phone Call (CC+), Caring Contacts without an introductory phone call (CC)
- Where
- United States
- Volunteers
- 666 people
- Sponsor
- St. Luke's Health System, Boise, Idaho
Sexual Dysfunctions, Psychological
Pharmacokinetics of Flibanserin in Postmenopausal Women With Hypoactive Sexual Desire Disorder (HSDD)
This trial examines the way flibanserin is metabolized in postmenopausal women with Hypoactive Sexual Desire Disorder.
- Trial name
- NCT01188603
- Testing
- flibanserin 100 mg dose every evening
- Where
- 4 sites in United States
- Volunteers
- 24 people
- Sponsor
- Sprout Pharmaceuticals, Inc
Peripheral Nerve Sheath Tumor
Tazemetostat in Malignant Peripheral Nerve Sheath Tumors
This phase 2, open label, single arm study will investigate the use of tazemetostat in patients with recurrent/refractory and/or metastatic malignant peripheral nerve sheath tumors.
- Trial name
- NCT04917042
- Testing
- Tazemetostat
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Florida
Care, Postoperative, Pain, Postoperative
Psychological Influences on Postoperative Recovery
The primary hypothesis tested in this project is that the preoperative behavioral stress response predicts postoperative behavioral and clinical recovery of children undergoing surgery.
- Conditions
- Care, Postoperative, Pain, Postoperative, Surgical Procedures, Operative, Otorhinolaryngologic Surgical Procedures
- Trial name
- NIH (NCT00581139)
- Testing
- Preoperative Preparation Program (Child Life Specialist), Midazolam, Parental Presence during Induction of Anesthesia
- Where
- United States
- Volunteers
- 241 people
- Sponsor
- University of California, Irvine
Childhood Traumatic Grief, Post Traumatic Stress
Randomized Controlled Trial of Trauma-focused CBT in Tanzania and Kenya
The primary goal is to study the effectiveness of Trauma-focused Cognitive Behavioral Therapy (TF-CBT) in treating traumatic grief and traumatic stress for orphaned children and young adolescents in two East African sites with…
- Conditions
- Childhood Traumatic Grief, Post Traumatic Stress, Post Traumatic Stress Disorder, Depressive Symptoms
- Trial name
- NCT01822366
- Testing
- Trauma-focused Cognitive Behavioral Therapy
- Where
- 3 sites in United States, Kenya and 1 more
- Volunteers
- 1,280 people
- Sponsor
- Duke University
Psychological Trauma, Depression
PCORI-1306-02918 Evaluation of Parent-based Programs to Support Children After Traumatic Injury
Children presenting to the University of Iowa Health Care System (UIHC), Blank Children's Hospital (Blank), Children's Hospital of Minneapolis, and Kansas City Mercy Children's Hospital with an injury resulting in admission will…
- Conditions
- Psychological Trauma, Depression, Coping
- Trial name
- NCT02323204
- Testing
- Link for Injured Kids, So you've been in an accident
- Where
- 4 sites in United States
- Volunteers
- 628 people
- Sponsor
- Marizen Ramirez
Anxiety Symptoms, Depressive Symptoms
Effects of a Single-session Implicit Theories of Personality Intervention on Early Adolescent Psychopathology
The goal of the project is to test whether a single-session intervention teaching incremental theories of personality, or the belief that one's personality is malleable, can strengthen recovery from social stress and reduce the…
- Trial name
- NCT03132298
- Testing
- Implicit Theories of Personality Program, Control Program
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Harvard University
Depression, Anxiety
Feasibility and Acceptability of W-GenZD vs CBT-light Teletherapy for Adolescents Seeking Mental Health Services
The primary aim of this study is to determine the feasibility and acceptability of the W-GenZD mobile application among a group of adolescents and who have screened and triaged into low-intensity treatment within the Children's…
- Trial name
- NCT05372913
- Testing
- Woebot for Adolescents (W-GenZD) Mobile Application, CBT-Lite Teletherapy Group
- Where
- United States
- Volunteers
- 141 people
- Sponsor
- Woebot Health
Klinefelter Syndrome, XXY Syndrome
Study of Psychological and Motor Effects of Testosterone in Adolescents With XXY/Klinefelter Syndrome
The purpose of this study is to determine if testosterone replacement therapy leads to changes in psychological factors and/or motor skills in adolescent males with 47,XXY (also called Klinefelter syndrome).
- Trial name
- TestoXXY/KS (NCT01585831)
- Testing
- Testosterone gel 1%
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- University of Colorado, Denver
Family Mindfulness-based Intervention in War-affected Families, Intergenerational Trauma
FMBI With War-affected Families
This study has two central research questions: 1) Is implementing a family mindfulness-based intervention with war-affected immigrant families through community based participatory research methods feasible?; and 2) Does the…
- Conditions
- Family Mindfulness-based Intervention in War-affected Families, Intergenerational Trauma, War-Related Trauma
- Trial name
- NCT05241314
- Testing
- Learning to BREATHE, After Deployment Adaptive Parenting Tools (ADAPT)
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Opioid-Related Disorders, NAS
MOms in REcovery (MORE) Study: Defining Optimal Care
Northern New England has among the highest rates of opioid dependence in the U.S. This region also has among the highest rates of opioid-related deaths in the U.S., with a disproportionate high rate among pregnant women with…
- Conditions
- Opioid-Related Disorders, NAS, Substance Use Disorders, Mental Health
- Trial name
- MORE (NCT04251208)
- Testing
- Observational Study
- Where
- 10 sites in United States
- Volunteers
- 2,510 people
- Sponsor
- Trustees of Dartmouth College