Clinical trials: Psychotic Disorder
Schizophrenia
A Study to Test if TV-46000 is Safe for Maintenance Treatment of Schizophrenia
The primary objective of the study is to evaluate the long-term safety and tolerability of TV-46000. The primary safety and tolerability endpoint is the frequency of all adverse events, including serious adverse events.
- Trial name
- SHINE (NCT03893825)
- Testing
- TV-46000
- Where
- 90 sites in United States, Bulgaria and 3 more
- Volunteers
- 336 people
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
Bipolar Disorder, Depression
Pediatric Bipolar Registry
The goal of the Pediatric Bipolar Registry (PBR) is to provide a comprehensive assessment regarding the diagnosis and treatment of pediatric bipolar disorder to children and adolescents with any current mood state and/or…
- Conditions
- Bipolar Disorder, Depression, Mania, Psychosis
- Trial name
- PBR (NCT02360267)
- Where
- United States
- Volunteers
- 334 people
- Sponsor
- The University of Texas Health Science Center, Houston
Hallucinations, Psychoses
Treatment of Hallucinosis/Psychosis in Parkinson's Disease by an Investigational Drug
The primary objective is to demonstrate that the investigational new drug, ACP-103, is well tolerated by, and will not worsen parkinsonism in, patients with Parkinson's disease and psychosis.
- Conditions
- Hallucinations, Psychoses, Parkinson's Disease
- Trial name
- NCT00087542
- Testing
- ACP-103
- Where
- 13 sites in United States
- Volunteers
- 60 people
- Sponsor
- ACADIA Pharmaceuticals Inc.
Mental Disorder
Effects of an Internet Use Disorder and Internet Gaming Disorder Early Intervention Program
Background. In the last two decades Internet usage has grown vastly. Pathological Internet usage (IUD; Internet Use Disorder) is associated with severe mental health problems affecting social, academic and daily life functioning.
- Trial name
- PROTECT+ (NCT03582839)
- Testing
- PROTECT+
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Pädagogische Hochschule Heidelberg
Dissociative Disorders, Schizophrenia
Prevalence of Dissociative Disorders in Children
Schizophrenia beginning before 18 years is a clinical entity not well known because of its low incidence and difficulties in the clinical diagnosis.
- Trial name
- NCT01512641
- Testing
- Primary stage, Secondary stage
- Where
- 4 sites in France
- Volunteers
- 301 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Acute Psychotic Symptoms
Quality Project to Evaluate and Validate the FAST-O Rating Scale
The purpose of this project is to test the reliability of the FAST-O Rating Scale in patients at acute wards or psychiatric intensive care units.
- Trial name
- FAST-O (NCT00913731)
- Where
- 5 sites in Sweden
- Volunteers
- 111 people
- Sponsor
- AstraZeneca
Schizophrenia Patients, Psychoeducation
The Effect of Psychosocial Skills Focused Group Psychoeducation in Schizophrenia Patients
The aim of this study was to evaluate the effect of psychosocial skills-oriented group psychoeducation on functional recovery, treatment adherence and mental well-being in patients with schizophrenia.
- Conditions
- Schizophrenia Patients, Psychoeducation, Functional Status, Treatment Outcome
- Trial name
- Schizophrenia (NCT06872424)
- Testing
- psychosocial skills-oriented group psychoeducation
- Volunteers
- 34 people
- Sponsor
- Gazi University
Psychotic Disorders, Autism Spectrum Disorder
EEG Microstates Across At-Risk Mental States
The goal of this observational study is to compare subjects with at-risk-mental-state, early psychosis, schizophrenia, depression, and autism spectrum disorders, with healthy controls (N = 21 x 6).
- Conditions
- Psychotic Disorders, Autism Spectrum Disorder, Major Depressive Disorder, Schizophrenia
- Trial name
- DEMETER (NCT06045897)
- Testing
- EEG 64 channels, Polysomnography 19 electrodes, Light hypnosis
- Where
- France
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier St Anne
Schizophrenia, Psychosis
Aripiprazole Treatment of Prodromal Patients
We hypothesize that symptoms will improve in patients who meet diagnostic criteria for the schizophrenia prodrome when they are prescribed aripiprazole.
- Trial name
- NCT00237874
- Testing
- Aripiprazole
- Where
- 2 sites in United States
- Volunteers
- 15 people
- Sponsor
- Yale University
Schizophrenia, Schizophreniform Disorder
Biomarkers in First Episode Schizophrenia
This study will identify and evaluate relevant biomarkers and structural brain imaging for understanding potential biological illness related mechanisms in medication-naïve subjects with early psychosis before and after…
- Conditions
- Schizophrenia, Schizophreniform Disorder, Schizoaffective Disorder, Depressed Type
- Trial name
- NCT02033382
- Where
- United States
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Schizophrenia, Schizoaffective Disorder
Academic-Community EPINET (AC-EPINET)
The investigators propose to examine the effects of CSC services delivered via TH (CSC-TH) versus the standard clinic-based CSC model (CSC-SD) on engagement and outcomes in a 12-month, randomized trial.
- Conditions
- Schizophrenia, Schizoaffective Disorder, Schizophreniform Disorders, Major Depression With Psychotic Features
- Trial name
- AC-EPINET (NCT04497857)
- Testing
- Coordinated Specialty Care (CSC)
- Where
- 6 sites in United States
- Volunteers
- 74 people
- Sponsor
- Indiana University
Schizophrenia, Bipolar Disorder
Integrated Care Including Assertive Community Treatment in Early Psychosis
Improvement of clinical long-term outcome through the implementation of early detection and intervention within a specialized network of integrated care (ACT and hometreatment) for adolescents and young adults with a first…
- Trial name
- ICEP (NCT02037581)
- Testing
- Early detection and Integrated Care, Standard Care
- Where
- Germany
- Volunteers
- 120 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Schizophrenia, Cognitive Impairment
From Brain Currents to Interpersonal Flow: Investigating the Social Processing Stream of Schizophrenia
The overall objective of this project is to identify the neural signature of the impaired ability to relate socially seen in individuals with schizophrenia.
- Conditions
- Schizophrenia, Cognitive Impairment, Social Competence
- Trial name
- ecoval (NCT03543553)
- Testing
- This is not an intervention study
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Depressive Disorder, Mental Disorder in Adolescence
A Clinical Study on the Effects of Inhalation of Volatile Oil of Cang-Ai Via the Nose on Patients With Depression
In this study, 60 depressed patients who meet the criteria will randomly be divided into a test group and a control group, with 30 patients in each group.
- Trial name
- NCT05251779
- Testing
- Volatile Oil of Cang-Ai, Bergamot essential oils
- Volunteers
- 60 people
- Sponsor
- Jieqiong Cui
Schizophrenia
The Safety and Effectiveness of Latuda® Post-marketing Surveillance in the Treatment of Chinese Schizophrenia Patients
It's a prospective, non-interventional, observational Post-marketing Surveillance..
- Trial name
- NCT04432688
- Testing
- Lurasidone HCl
- Where
- 7 sites in China
- Volunteers
- 3,192 people
- Sponsor
- Marubeni Pharmaceuticals (Suzhou) Co., Ltd.
Mental Disorders, Child, Mental Disorder in Adolescence
Equine Assisted Services in Children and Adolescents With Mental Illness
Due to an increasing amount of children and adolescents are suffering from mental illnesses i Sweden. Early preventive psychological interventions are important to avoid a long-time use of medicines.
- Conditions
- Mental Disorders, Child, Mental Disorder in Adolescence, Anxiety Disorders, Anxiety
- Trial name
- EASiCAM (NCT05670990)
- Testing
- Equine assisted therapy
- Where
- Sweden
- Sponsor
- Peter Nymberg
Schizophrenia, Bipolar Disorder
Longitudinal Effect of Electroconvulsive Therapy on Schizophrenia and Bipolar Disorder: a MRI Study
For more severe and treatment-resistant cases in schizophrenia and bipolar disorder, electroconvulsive therapy (ECT) is often very effective.
- Trial name
- NCT03651674
- Testing
- ECT treatment, Drug treatment
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Xidian University
Psychotic Disorders
Implementation of National Guidelines for Treatment of Psychoses
The study is a combined health services research study and a clinical patient outcomes sub-study. The aims of the study are to give new knowledge on (RQ1) current implementation in mental health services of four evidence based…
- Trial name
- NCT03271242
- Testing
- Systematic implementation support, No implementation support
- Volunteers
- 325 people
- Sponsor
- University Hospital, Akershus
Schizophrenia, Schizophreniform Disorder
DECIFER: Depression and Citalopram In First Episode Recovery
This study seeks to examine the effectiveness of citalopram added to treatment with any oral or injectable second-generation antipsychotic plus standardized psychoeducation in first episode schizophrenia patients.
- Trial name
- DECIFER (NCT01041274)
- Testing
- Citalopram, Psychoeducation, Cognitive Behavioral Therapy (CBT)
- Where
- United States
- Volunteers
- 95 people
- Sponsor
- NYU Langone Health
Diabetes, Hypertension
Pharmacy Interventions to Improve Chronic Disease Medication Refill
Compare the effectiveness of 3 strategies by pharmacists to decrease the time to refill of prescriptions for common chronic diseases (diabetes, hypertension, hyperlipidemia, heart failure, depression, psychoses).
- Conditions
- Diabetes, Hypertension, Hyperlipidemia, Heart Diseases
- Trial name
- NCT00469365
- Testing
- pharmacist contact with the patient via telephone, Pharmacist contact with the patient's physician via fax, Usual care
- Where
- United States
- Volunteers
- 3,048 people
- Sponsor
- Medical University of South Carolina