Clinical trials: Ptosis, Eyelid
Amblyopia, Refractive Errors
Vision Screening for the Detection of Amblyopia
INTRODUCTION. Amblyopia is defined as the loss of visual acuity (VA) in one or both eyes, without any obvious structural or pathological anomalies.
- Conditions
- Amblyopia, Refractive Errors, Anisometropia, Strabismus
- Trial name
- NCT01430247
- Testing
- Amblyopia screening
- Where
- Croatia
- Volunteers
- 7,000 people
- Sponsor
- Mladen Busic
Mild Ptosis, Moderate Ptosis
A Newly Modified Technique for Levator Muscle Tucking in Blepharoptosis Surgery: An Egyptian Tertiary Center Study
Mild to moderate blepharoptosis with good levator function is usually corrected by levator muscle resection or advancement with their modifications with high success rate.
- Trial name
- Lidtucking (NCT04883853)
- Testing
- Mild _moderate Ptosis tucking
- Where
- Egypt
- Volunteers
- 180 people
- Sponsor
- Ain Shams University
Ptosis, Eyelid
Efficacy of Aurosling in Frontalis Sling Suspension Surgery
To Study the Efficacy of Aurosling as a suspension material in Frontalis suspension surgery in ptosis
- Trial name
- NCT00753831
- Testing
- Aurosling
- Where
- India
- Volunteers
- 16 people
- Sponsor
- Aurolab
Upper Eyelid Dynamics
Upper Eyelid Dynamics in Pediatric Blepharoptosis Using High Speed Videography
Evaluation of the Upper Eyelid Dynamics in Simple Congenital Blepharoptosis before and after Levator Muscle Resection Using High speed Photography
- Trial name
- NCT06976645
- Testing
- Levator muscle resection
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Minia University
Blepharoptosis
Surgical Management of Blepharoptosis
Comparison of the results of levator resection operation with the use of fixed sutures technique in which the levator muscle is approached through skin incision and the muscle shortened and sutured directly to the tarsus then the…
- Trial name
- NCT03149367
- Testing
- levator muscle resection with fixed sutures technique, Levator muscle resection with adjustable sutures technique
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Assiut University
Eyelid Ptoses, Ectropion Eyelids
Objective Evaluation of the Effect of Oculoplastic Operations Using the Vectra M 3D Imaging System
An objective assessment of that part of the spectrum of ophthalmic eyelid surgeries that focuses on correcting the position of entropy (e.g.
- Conditions
- Eyelid Ptoses, Ectropion Eyelids, Entropion;Eye
- Trial name
- NCT06040671
- Testing
- Vectra M3 imaging
- Where
- Czechia
- Volunteers
- 80 people
- Sponsor
- University Hospital Ostrava
Blepharoptosis, Lagophthalmos
Magnetic Correction of Eye Lid Paralysis
Objective 1: Determine the safety and feasibility of externally mounted magnets for extended management of chronic eyelid movement disorders by measuring visual acuity and corneal and skin integrity and comfort over 8 weeks of…
- Conditions
- Blepharoptosis, Lagophthalmos, Facial Paralysis
- Trial name
- NCT02988856
- Testing
- Magnetic lid system
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Kevin Houston
Blepharoptosis
Management of Severe Congenital Blepharoptosis
Frontalis sling surgery was carried out using Ptose-up under general anaesthesia for patients with severe congenital ptosis.
- Trial name
- NCT04214379
- Testing
- Ptosis surgery
- Where
- Egypt
- Volunteers
- 15 people
- Sponsor
- Minia University
Strabismus, Esotropia
Bupivacaine Injection of Eye Muscles to Treat Strabismus
This study seeks to determine if bupivacaine injection of eye muscles can make them stronger and stiffer, and thereby correct the position of eyes that are turned in or mis-aligned, a condition generally termed strabismus.
- Conditions
- Strabismus, Esotropia, Exotropia, Graves Disease
- Trial name
- NCT01616108
- Testing
- Bupivacaine
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Smith-Kettlewell Eye Research Institute
Ptosis
A Prospective Cohort Study on Visual Function and Psychological Conditions Before and After Surgery for Congenital Ptosis
The goal of this observational study is to learn about the 6-month effects of Levator Resection combined with Fascial Sheath Suspension surgery in patients who undergo this procedure to treat congenital ptosis.
- Trial name
- NCT07534436
- Where
- China
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Dermatochalasis, Blepharoptosis
Vibration-Assisted Anaesthesia
Aim of study is to investigate whether a small, non-invasive vibrating device applied to the forehead during local anaesthetic administration reduces the pain of the injection.
- Trial name
- NCT00793988
- Testing
- Vibration-assisted anaesthesia, Switched-off vibrating device
- Where
- Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Ptosis, Eyelid
Comparison of Different Surgical Treatments for Severe Ptosis Correction
Main research purposes of this research is to compare the therapeutic effect and safety of the superior levator muscle shortening combined with the tarsus resection and the traditional frontal muscle flap in the correction of…
- Trial name
- NCT03916107
- Testing
- Levator muscle and tarsus resection, Frontalis flap
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Thymidine Kinase 2 (TK2)
A RETROspective Study of Patients With TK2d
This is a medical chart review study to collect information for patients who have been taking pyrimidine nucleosides for treatment of TK2 deficiency.
- Trial name
- RETRO (NCT03701568)
- Testing
- dC/dT
- Where
- 8 sites in United States, Israel and 1 more
- Volunteers
- 38 people
- Sponsor
- Zogenix MDS, Inc.
Blepharoptosis
Study of Safety of RVL-1201 in Treatment of Blepharoptosis
Phase 3 study to evaluate the extended safety of RVL-1201 compared to placebo for treatment of blepharoptosis. Eligible subjects will be randomized to one of 2 treatment arms.
- Trial name
- NCT03536949
- Testing
- RVL-1201, Vehicle ophthalmic solution
- Where
- 35 sites in United States
- Volunteers
- 234 people
- Sponsor
- RVL Pharmaceuticals, Inc.
Blepharoptosis, Ptosis, Eyelid
Clinical Trial Comparing Two Non-Surgical Treatments for Severe Blepharoptosis
This clinical trial will evaluate two non-surgical devices designed to improve eye lid opening for patients with severe Blepharoptosis (incomplete opening of the eyelids).
- Conditions
- Blepharoptosis, Ptosis, Eyelid, Myasthenia Gravis, Stroke
- Trial name
- NCT04678115
- Testing
- Magnetic Levator Prosthesis (MLP), Kinesiotape Frontalis Sling (KTFS)
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Massachusetts Eye and Ear Infirmary
Blepharoptosis
Eyelid Position Interdependence in Involutional Ptosis Patients Submitted to 10% Phenylephrine
The primary aim of this study is to quantify eyelid position changes in tested and opposite eyes in ptosis patients submitted to 1, 2 or 4 drops of 10% phenylephrine in one eye.
- Trial name
- NCT00864656
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- University of Sao Paulo
Blepharoptosis
Study of Safety and Efficacy of RVL-1201 in the Treatment of Blepharoptosis
Phase 3 study to evaluate the safety and efficacy of treatment with RVL-1201 compared to placebo for treatment of blepharoptosis. Eligible subjects will be randomized to one of 2 treatment arms.
- Trial name
- NCT03565887
- Testing
- RVL-1201, Vehicle ophthalmic solution
- Where
- 36 sites in United States
- Volunteers
- 164 people
- Sponsor
- RVL Pharmaceuticals, Inc.
Blepharoptosis
Custom Print Megnetic Levator Prosthesis Pilot Comparison
Study the device feasibility of non-surgical treatment for blepharoptosis (inability to open the eyelid) consisting of a biocompatible magnetic element adhered to the upper eyelid and a second magnet above the eye on a custom…
- Trial name
- NCT04807855
- Testing
- The cMLP device
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Skelmet Inc
Congenital Ptosis
Levator Resection with3 Point Fixation Versus 2 Point Fixation Tucking for Congenital Ptosis
to evaluate the surgical effect of levator aponeurosis resection Versus two point fixation levator aponeurosis Tucking for Congenital Ptosis
- Trial name
- NCT03240107
- Testing
- levator resection, levator tucking
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Heba Hamdy Ibrahim Mohammed
Blepharoptosis, Ptosis, Eyelid
Clinical Trial to Improve the Magnetic Levator Prosthesis
Blepharoptosis (incomplete opening of the eyelids) occurs because of a disruption in the normal agonist-antagonist neuro-muscular complex balance. An external device could restore eyelid movement.
- Conditions
- Blepharoptosis, Ptosis, Eyelid, Myasthenia Gravis, Stroke
- Trial name
- NCT03818204
- Testing
- Magnetic Levator Prosthesis (MLP)
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Massachusetts Eye and Ear Infirmary