Clinical trials: Puerperal Disorders
HIV/AIDS
A Peer-Led Intervention to Improve Postpartum Retention in HIV Care
The purpose of this study is to test the efficacy of a theory-driven peer intervention for pregnant and postpartum women living HIV.
- Trial name
- NCT04168008
- Testing
- WISH Adherence, WISH Parenting
- Where
- 7 sites in United States
- Volunteers
- 151 people
- Sponsor
- University of Pennsylvania
Post-Traumatic Stress Disorder in Adolescence, PTSD - Post Traumatic Stress Disorder
Empowering Perinatal Adolescents Through Writing
This is a feasibility and acceptability study of Written Exposure Therapy (WET) for PTSD in pregnant and postpartum adolescents and youth with PTSD.
- Conditions
- Post-Traumatic Stress Disorder in Adolescence, PTSD - Post Traumatic Stress Disorder, PTSD and Trauma-related Symptoms, Pregnancy and PTSD
- Trial name
- EMPWR (NCT06771817)
- Testing
- Written Exposure Therapy
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- University of Texas Southwestern Medical Center
Postpartum Depression
Postpartum Depression and Cesarean Section
The purpose of this retrospective study is to determine if there is an increase in postpartum depression (PPD) among women who undergo an emergency cesarean section as opposed to a planned cesarean section.
- Trial name
- NCT00370903
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Oklahoma State University Center for Health Sciences
Postpartum Depression
Social Media, Teen Moms and PPD
Approximately 400,000 live births occur to adolescents in the United States annually. Of the 50% of adolescent mothers who experience depressive symptoms, less than 25% comply with referrals for depression evaluation and…
- Trial name
- NCT01967394
- Testing
- Use of internet based social marketing intervention, No use of social media
- Where
- 8 sites in United States
- Volunteers
- 287 people
- Sponsor
- University of Louisville
Postpartum Disorder
Effect of KT Taping on Waist-to-hip Ratio, Abdominal Strength and Body Image Concerns in Postpartum Females.
This study is aimed at determining the effect of kinesio taping on waist to hip ratio, abdominal muscle strength and body image concerns in postpartum females.
- Trial name
- NCT05010837
- Testing
- Kinesio taping with abdominal exercises, Abdominal exercises
- Where
- Pakistan
- Volunteers
- 24 people
- Sponsor
- Riphah International University
Postpartum Depression, Quality of Life
Whether Probiotics Use in Neonate and Infant Improve Their Mother's Life Quality
Postpartum depression and poor quality of life during postpartum were an vital issue in recent years. Infant's health condition was thought to be a possible reasons related mother's postpartum quality of life, and functional…
- Conditions
- Postpartum Depression, Quality of Life, Functional Gastrointestinal Disorders, Probiotics
- Trial name
- NCT04741971
- Testing
- Probiotics group, Non-probiotics group
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Buddhist Tzu Chi General Hospital
Anemia, Ferritin
Effect of Timing of Umbilical Cord Clamping on Haematological and Clinical Outcomes of Infants
In developing countries up to 50% of children become anemic by 12 months of age(1. Iron deficiency anemia is a major risk factor for neonatal and infantile mortality and morbidity in Pakistan.
- Conditions
- Anemia, Ferritin, Complications, Hemorrhage
- Trial name
- NCT01081977
- Testing
- Early Cord Clamping, Delayed Cord Clamping
- Where
- Pakistan
- Volunteers
- 340 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
COVID19, Coronavirus Infection
Northeast COVID-19 and Pregnancy Study Group
A prospective and retrospective cohort study. The objective will to determine the frequency of COVID-19 in pregnant and postpartum women hospitalized with flu syndrome, to evaluate clinical and laboratory predictors of COVID-19…
- Conditions
- COVID19, Coronavirus Infection, Pregnancy Disease, Severe Acute Respiratory Syndrome
- Trial name
- NCOVIP (NCT04462367)
- Where
- Brazil
- Volunteers
- 180 people
- Sponsor
- Instituto Materno Infantil Prof. Fernando Figueira
Simulation Training, Nursing
The EFFECT of SIMULATION-BASED TRAINING on POSTPARTUM HAEMORRHAGE MANAGEMENT SKILLS
This study was planned to determine the effect of simulation-based training using two different reality levels-visually enhanced mental simulation (VEMS) and hybrid simulation-on postpartum haemorrhage (PPH) management skills in…
- Conditions
- Simulation Training, Nursing, Postpartum Hemorrhage
- Trial name
- (SBT) (NCT06872879)
- Testing
- VEMS Simulation, Hybrit Simulation
- Volunteers
- 64 people
- Sponsor
- Bandırma Onyedi Eylül University
Intrauterine Devices
Study on Medical Records of Women Using an Intrauterine Device (IUD) to Analyze the Risks That the IUD Will be Expelled or Perforates the Womb in Relation to Breastfeeding, the Point in Time When the IUD Was Inserted After Childbirth and in Relation to Different Types of IUDs
Study to analyze electronic medical records of women using an intrauterine device (IUD). The study was required by the FDA for the marketed IUD Mirena (US Post-marketing requirement; short name of study: APEX IUD).
- Trial name
- APEX IUD (NCT03754556)
- Testing
- Intrauterine device
- Where
- 4 sites in United States
- Volunteers
- 326,658 people, healthy volunteers welcome
- Sponsor
- Bayer
Preeclampsia Postpartum, Adverse Pregnancy Outcomes
A Community Health Worker Intervention to Address Adverse Pregnancy Outcomes
United States maternal mortality and preterm birth rates are among the highest among high-income countries due in part to a combination of racial, regional and socioeconomic disparities in access to care and overall health.
- Trial name
- AW2H (NCT06353256)
- Testing
- usual postpartum care, usual postpartum care + community health worker intervention
- Where
- 2 sites in United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Postpartum Hemorrhage
Tampostat for Management of Postpartum Hemorrhage
The purpose of the study is to evaluate the safety, feasibility and applicability of a new device 'Tampostat' in the management of primary postpartum hemorrhage and compare the efficacy of 'Tampostat' in terms of arresting…
- Trial name
- NCT02416089
- Testing
- Tampostat, Condom catheter tamponade
- Where
- Bangladesh
- Volunteers
- 344 people
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Malnutrition in Pregnancy, Preterm Birth
Improving Cognition and Gestational Duration With Targeted Nutrition
The goal of this clinical trial is to test (1) a novel maternal ready-to-use supplementary food and (2) a novel cognitive behavioral therapy intervention in undernourished Sierra Leonean women.
- Conditions
- Malnutrition in Pregnancy, Preterm Birth, Child Development, Postpartum Depression
- Trial name
- COGENT (NCT05949190)
- Testing
- M-RUSF+ (Maternal Ready-to-Use Supplementary Food + DHA/EPA/choline), M-RUSF (Maternal Ready-to-Use Supplementary Food), Azithromycin
- Where
- 10 sites in Sierra Leone
- Volunteers
- 1,660 people
- Sponsor
- Washington University School of Medicine
Maternal Death, Neonatal Death
Evaluating the Effects of SMS Text Messaging Support System Among Frontline Health Workers in Ghana
Introduction Maternal and neonatal mortality continue to be to be prominent public health issues in sub Saharan Africa including Ghana, with slow progress made towards attainment of Millennium Development Goals (MDG) 4 \& 5.
- Conditions
- Maternal Death, Neonatal Death, Postpartum Haemorrhage, Pre-eclampsia
- Trial name
- Accelerate (NCT02468310)
- Testing
- Maternal and neonatal emergency protocols
- Where
- Ghana
- Volunteers
- 65,831 people, healthy volunteers welcome
- Sponsor
- Hannah Brown Amoakoh
Postpartum Haemorrhage
Treatment of Postpartum Haemorrhage (PPH) Using Misoprostol in Home Births
A double-blind individual randomized controlled study of misoprostol vs. placebo for treatment in homebirths in the Chitral district, in the Khyber Pakhtunkhwa province in Pakistan.
- Trial name
- NCT01485562
- Testing
- Misoprostol
- Where
- Pakistan
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Depression, Anxiety, Antenatal Depression
Integration of Stepped Care for Perinatal Mood and Anxiety Disorders Among Women Attending MCH Clinics
Perinatal mood and anxiety disorders (PMAD), defined as depression and anxiety during pregnancy or up to 1 year postpartum, account for substantial morbidity and mortality among birthing people globally especially in low- and…
- Conditions
- Depression, Anxiety, Antenatal Depression, Postnatal Depression
- Trial name
- IPMH (NCT06456307)
- Testing
- Integrated Perinatal Mental health program (systematic screening for PMAD, PM+ and tele-psychiatry)
- Where
- 2 sites in Kenya
- Volunteers
- 2,970 people, healthy volunteers welcome
- Sponsor
- Kenyatta National Hospital
Postpartum Hemorrhage
Effect of Magnesium Sulphate Pre-exposure on Oxytocin-induced Contractility in Desensitized Human Myometrium - an in Vitro Study
Postpartum hemorrhage (PPH) is the loss of more than 500ml of blood within 24 hours after delivery. It is a major cause of maternal morbidity and mortality across the globe.
- Trial name
- NCT02647268
- Testing
- Oxytocin, Magnesium Sulphate
- Where
- Canada
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Postpartum Hemorrhage, Maternal Morbidity
Secondary Postpartum Hemorrhage
Postpartum hemorrhage (PPH) remains one of the leading causes of maternal mortality and morbidity worldwide, including in France, where it accounts for approximately 20% of maternal mortality.
- Conditions
- Postpartum Hemorrhage, Maternal Morbidity, Retained Placenta, Postpartum Endometritis
- Trial name
- SPPH (NCT03840889)
- Testing
- Data collection
- Where
- 10 sites in France
- Volunteers
- 80 people
- Sponsor
- University Hospital, Clermont-Ferrand
Microbial Colonization
Comparing Impacts of Donor Human Milk to Formula Supplementation on the Gut Microbiome of Full-term Infants
The goal of this pilot randomized controlled trial (RCT) is to examine donor human milk (DHM) as a clinical intervention targeted at achieving beneficial microbiome signatures in full-term infants who are exposed to intrapartum…
- Trial name
- PPDHM (NCT05815433)
- Testing
- Donor Human Milk - Nutritional Replacement
- Where
- Canada
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Perinatal Depression, Postpartum Depression
Integrating Text Messages Into the Mothers and Babies Course
This project is aimed at enhancing the effectiveness and scalability of the Mothers and Babies 1-on-1 Course (MB) among home visiting programs.
- Trial name
- NCT03420755
- Testing
- Mothers and Babies 1-on-1, Mothers and Babies Plus Text
- Where
- United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Northwestern University