Clinical trials: Pulmonary Function
Congenital Heart Disease
International Multicenter Outcomes of Transcatheter Pulmonary Flow Restrictors in Congenital and Acquired Heart Disease
The international multicenter registry aims to collect real-world data on clinical outcomes and evaluate the net clinical success of transcatheter microvascular plug (MVP)-based pulmonary flow restrictors (PFRs) in patients with…
- Trial name
- RESTRICT (NCT07791069)
- Testing
- Transcatheter pulmonary flow restriction
- Where
- 5 sites in France, Germany and 3 more
- Volunteers
- 150 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Cystic Fibrosis (CF)
Autogenic Drainage Versus Mechanical Percussion in Children With Cystic Fibrosis
The goal of this clinical trial is to compare the effects of autogenic drainage and mechanical percussion on lung function, dyspnea, and quality of life in children with cystic fibrosis.
- Trial name
- ADMP-CF (NCT07729787)
- Testing
- Autogenic Drainage, Mechanical Percussion
- Where
- Pakistan
- Volunteers
- 32 people
- Sponsor
- Riphah International University
Pulmonary Hypertension
Evaluation of the Strength of Handgrip in Patients With Pulmonary Artery Hypertension
Our study aims to investigate the changes in muscle strength and muscle mass in PAH patients compared to healthy individuals and determine its effects on prognosis.
- Trial name
- NCT05447390
- Testing
- Handgrip strength test
- Where
- Turkey (Türkiye)
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Gazi University
Healthy
Effect of Hatha Yoga on Pulmonary Function
The goal of this clinical trial is to to investigate the acute and chronic effects of a four-week hatha yoga (HY) exercise program with different durations (60 min and 30 min) on pulmonary function in sedentary young…
- Trial name
- NCT06468410
- Testing
- long duration Hatha Yoga, short duration Hatha Yoga, Control group
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Monira Aldhahi
Cystic Fibrosis
Using Remote Telemonitoring to Detect Early Decline in Lung Function & Streamline Clinics in Adults With Cystic Fibrosis
Lung Health research study (Development of a predictive model) - To determine whether the I-neb breathing parameters (flow data) can act as a surrogate marker for lung function (Forced Expiratory Volume in 1 second FEV1) hence…
- Trial name
- RIGHT-CF (NCT02399241)
- Testing
- Bluetooth enabled nebuliser device (I-neb)
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Congenital Heart Disease, Pulmonary Hypertension
MRI and Computational Simulation Cardiology Study
The purpose of this study is to (1) quantify cardiovascular anatomy and physiology using magnetic resonance imaging under both resting and exercise conditions in patients who have congenital heart disease and in age-matched…
- Trial name
- NCT03149341
- Testing
- Magnetic Resonance Imaging
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Stanford University
Lung Cancer
Tracking of Respiratory-Induced Tumor Motion Using Implanted Fiducials
Objectives: To determine the safety of fiducial implantation. To determine the extent/rate of migration of radio-opaque fiducials placed in lung tumors and adjacent normal tissue.
- Trial name
- NCT00500513
- Testing
- CT Scans, Implanted markers, Radiation Treatment (RT)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- M.D. Anderson Cancer Center
Asthma
Study In Airway Physiology In Children SERETIDE DISKUS ® Inhlaer and FLIXOTIDE® Inhaler Are Trademarks of GSK Group of Companies.
Comparison of two asthma treatments by lung function measures.
- Trial name
- NCT00169546
- Testing
- Salmeterol/fluticasone propionate, Fluticasone propionate
- Where
- 2 sites in New Zealand, United Kingdom
- Volunteers
- 64 people
- Sponsor
- GlaxoSmithKline
Leiomyomatosis
Official Record of Patients Diagnosed With Lymphangioleiomyomatosis (LAM)
Pulmonary lymphoangioleiomyomatosis (LAM) is a rare destructive lung disease typically affecting women of childbearing age. Currently, there is no effective therapy for the disease and the prognosis is poor.
- Trial name
- NCT00001869
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Chronic Thromboembolic Pulmonary Hypertension
Cardiac Self-Efficacy in Patients With Chronic Thromboembolic Pulmonary Hypertension
This study aims to analyze the effect of Pulmonary Endarterectomy (PEA) on patients' self-confidence in managing their chronic illness.
- Trial name
- CTEPH3 (NCT07272798)
- Where
- Syria
- Volunteers
- 10 people
- Sponsor
- Damascus University
Congenital Diaphragmatic Hernia
Microbiome and Volatile Organic Compounds in Patients With CDH
Despite improved prenatal diagnostics and therapeutic possibilities, congenital diaphragmatic hernia (CDH) represents a cross-disciplinary challenge.
- Trial name
- CDHVOCS (NCT03787160)
- Testing
- initial VOC, initial fecal microbiome, initial pulmonary microbiome
- Where
- Austria
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Mental Health Wellness 1, Pandemic
Collaborative Outcomes Study on Health and Functioning During Infection Times During COVID-19 Pandemic
Observational, cross-sectional, multi-center, multi-wave survey, assessing characteristics and predictors of physical and mental health as well as health behaviors during COVID-19 pandemic, targeting the general population…
- Trial name
- COH-FIT (NCT04383470)
- Where
- Greece
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- University of Padova
Cystic Fibrosis
Comparison Between RTX (Biphasic Cuirass Ventilator) and Physiotherapy in Cystic Fibrosis Patients
The purpose of this study is to compare the effectiveness of different mucous clearance techniques in cystic fibrosis patients
- Trial name
- RTX (NCT00908505)
- Testing
- physiotherapy
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- Hadassah Medical Organization
Bronchiolitis
Follow up of Ventilatory Function in Infant After Bronchiolitis During the First Year of Life
A significant proportion of asthma is diagnosed during childhood. Bronchiolitis is the most common lower respiratory tract illness (LRI) in early life and the present work is a prospective study undertaken to highlight the…
- Trial name
- NCT00676351
- Testing
- body plethysmography
- Where
- France
- Volunteers
- 29 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Cystic Fibrosis
Time to Perform Lung Function Test in Cystic Fibrosis
Time to perform lung function test after chest physiotherapy in cystic fibrosis. The investigators study FEV1(forced expiratory volume in one second) and FVC (forced vital capacity).
- Trial name
- NCT01737801
- Testing
- Lung function test
- Where
- Sweden
- Volunteers
- 24 people
- Sponsor
- Karolinska University Hospital
Liver Function Tests Abnormalities
Liver Function Test Abnormalities in COVID-19
With the increasing number of COVID-19 infected patients, several studies reported that the liver is the most frequently affected organ after lung damage.
- Trial name
- COVID-19 (NCT04763395)
- Testing
- No intervention
- Where
- Egypt
- Volunteers
- 118 people
- Sponsor
- Sohag University
Respiratory-Gated Imaging Techniques
Functional Respiratory Imaging After Neostigmine or Sugammadex
The use of neuromuscular blocking agents (NMBAs) is still associated with postoperative pulmonary complications. The investigators rely on acceleromyography (AMG) of a peripheral nerve/muscle to assess the patients' breathing…
- Trial name
- FRINeoS (NCT02284412)
- Testing
- Neostigmine, Sugammadex, Water for injection
- Where
- Belgium
- Volunteers
- 13 people
- Sponsor
- Onze Lieve Vrouw Hospital
COPD
Impact of Walking Behind the COPD Patient on 6MWD
The six-minute walk test (6MWT) is a well established field exercise test to assess the functional exercise capacity in chronic obstructive pulmonary disease (COPD).
- Trial name
- NCT04033783
- Testing
- 6MWT - accompanied, 6MWT - not accompanied
- Where
- 2 sites in Switzerland
- Volunteers
- 49 people
- Sponsor
- University of Zurich
Cognitive Impairment, Covid19
The MentalPlus® for Assessment and Rehabilitation of Cognitive Function After Remission of the Symptoms of COVID-19
This study evaluates and rehabilitates the cognitive functions of attention, memory, visual perception, language, and executive by the mentalPlus® digital game of COVID-19 surviving patients after remission of symptoms.
- Conditions
- Cognitive Impairment, Covid19, Cognitive Dysfunction, Depression, Anxiety
- Trial name
- MP-COVID (NCT04632719)
- Testing
- The use of the MentalPlus® digital game for assessment and rehabilitation of cognitive function after remission of the symptoms of COVID-19
- Where
- 2 sites in Brazil
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Cystic Fibrosis
Increased Vitamin D Reduces Pulmonary Exacerbations in CF
The investigators study is designed to test the hypothesis that correction of vitamin D in CF patients can increase their lung function and decrease the number of their pulmonary exacerbations.
- Trial name
- NCT02043717
- Testing
- Vitamin D
- Where
- Israel
- Volunteers
- 90 people
- Sponsor
- Hadassah Medical Organization