Clinical trials: Pulmonary Function
Cystic Fibrosis
Treatment of Dysglycemia Using Sitagliptin in Adolescents With Cystic Fibrosis
This pilot study will be conducted in adolescents with cystic fibrosis (CF) without diabetes but with abnormal glucose tolerance, and will assess the effects of sitagliptin on glucose regulation.
- Trial name
- NCT01721382
- Testing
- Sitagliptin
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Nemours Children's Clinic
Bronchiolitis Obliterans Syndrome
Novel Pulmonary Function Measures for Diagnosis of Bronchiolitis Obliterans Syndrome Following Hematopoietic Stem-Cell Transplantation in Children
In this study, we will study 129Xe-MRI and LCI as tools for diagnosis of BOS in pediatric patients who have received Hematopoietic Stem Cell Transplantation (HSCT) and have been identified as eligible for this study.
- Trial name
- NCT04391335
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- The Hospital for Sick Children
Asthma, Asthma Exacerbations
Vitamin D In the Prevention of Viral-induced Asthma in Preschoolers
In this 7-month randomized controlled trial, children aged 1 to less than 6 years, with recurrent asthma attacks triggered mostly by colds, will receive a high dose of vitamin D or a placebo every 3.5 months during their usual…
- Conditions
- Asthma, Asthma Exacerbations, Preschool Child, Vitamin D
- Trial name
- DIVA (NCT03365687)
- Testing
- Vitamin D
- Where
- 9 sites in Canada
- Volunteers
- 323 people
- Sponsor
- Professor Francine Ducharme
Adolescent Idiopathic Scoliosis, Scoliosis Idiopathic
Effects of Vertebral Derotation on Pulmonary Functions
This study was conducted to determine the physiological and mechanical effects of physical training post surgical correction of adolescent scoliosis using vertebral derotation.
- Trial name
- NCT05805995
- Testing
- vertebral derotation
- Where
- 2 sites in Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
COPD (Chronic Obstructive Pulmonary Disease), COPD
Dupilumab in Type 2-Inflamed COPD Across the Full Spectrum of Airflow Limitation: An Italian Multicentre Retrospective Cohort Study
This multicentre retrospective cohort study describes lung function and patient-reported outcomes in adults with chronic obstructive pulmonary disease (COPD) and type 2 inflammation who received add-on dupilumab in routine…
- Conditions
- COPD (Chronic Obstructive Pulmonary Disease), COPD, Eosinophilia
- Trial name
- DUPICENTRO (NCT07788092)
- Testing
- Dupilumab
- Where
- 6 sites in Italy
- Volunteers
- 40 people
- Sponsor
- Azienda Ospedaliera di Perugia
Diabetes Mellitus, Kidney, CPB
Kidney Function in Diabetics During CPB (Cardio Pulmonary Bypass)
Filtration of urine in the kidney requires sufficient oxygen supply. The filtration of urine is greater in patents with diabetes.
- Trial name
- DM-ECC (NCT03405532)
- Testing
- DM-ECC
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Sahlgrenska University Hospital
Cystic Fibrosis
Do Physiotherapy Techniques Improve Posture During Admission for a Chest Infection in Adults With Cystic Fibrosis?
Hypothesis: The addition of a series of musculoskeletal techniques to normal optimal care for the treatment of a respiratory exacerbation in inpatient adults with cystic fibrosis, will lead to further improvements in pain…
- Trial name
- NCT00806884
- Testing
- Physiotherapy Musculoskeletal Treatment, Control group measurements
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- Royal Brompton & Harefield NHS Foundation Trust
Asthma in Children, Telerehabilitation
COVID-19 Pandemic Asthma Child Telerehabilitation Yoga
In our study, yoga asana and pranayama practices, which will be applied by video call from computer or phone, will be advantageous in terms of time, transportation and access to asthmatic children whose anxiety and anxiety levels…
- Conditions
- Asthma in Children, Telerehabilitation, Yoga
- Trial name
- NCT05684926
- Testing
- Telerehabilitation yoga
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Bartın Unıversity
Forward Head Posture, Muscle Tone
Relationship Between Head Posture Muscles, Pulmonary Capacity and Functional Capacity: a Myotonometric Assessment
Forward head posture (FHP) is known to have a large influence on respiratory function by weakening the respiratory muscles. This cross-sectional study is designed to examine the relationship between the tonus, stiffness, and…
- Conditions
- Forward Head Posture, Muscle Tone, Muscle Stiffnes, Muscle Elasticty
- Trial name
- NCT04253821
- Testing
- muscle tonus, stiffness and elasticity,six-minute walk test, Pulmonary function tests, The neck disability index
- Where
- Turkey (Türkiye)
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Cagtay Maden
Neuromuscular Block, Residual
Diaphragm Function After Reversal of Rocuronium-induced Neuromuscular Blockade With Sugammadex or Neostigmine in Children
This study is to evaluate the recovery of diaphragm function and atelectasis after reversal of neuromuscular blockade with Neostigmine and Sugammadex using lung ultrasound and diaphragm ultrasound for children aged 2 to 7 who are…
- Trial name
- NCT05724550
- Testing
- Sugammadex, Neostigmine
- Where
- South Korea
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Muscular Dystrophy
Effect of Aquatic Therapy on Pulmonary Functions in Patients With Muscular Dystrophy
This study aimed to assess the efficacy of aquatic therapy on pulmonary functions in patients with muscular dystrophy.
- Trial name
- NCT04574934
- Testing
- aquatic therapy
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- South Valley University
Durability of Implanted Intravascular Stents, Hemodynamic Effect of Implanted Intravascular Stents
Intravascular Stents Fracture Effects
The goal of the study is to evaluate long term durability and hemodynamic effect of implanted stents in the aortic arch and in pulmonary artery branches.
- Trial name
- NCT01382381
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Obesity, Asthma
Obesity-asthma Endophenotype and Diaphragm Mobility in Adolescence
Obesity and asthma share changes that may begin in the fetal development phase. The endophenotype obesity-asthma presents as main characteristic a pattern of inflammatory response different from the habitual Th2 profile of…
- Trial name
- NCT03029936
- Where
- Brazil
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Pernambuco
Asthma, Lung Function Decreased
Dietary Intake in Adults From the GA2LEN Folow-up Survey
The Nutrition Study of the GA2LEN Follow-Survey was designed to investigate the association between usual dietary intake and allergic and respiratory outcomes in adults across Europe.
- Conditions
- Asthma, Lung Function Decreased, Food Allergy, Allergic Sensitisation
- Trial name
- NCT03251157
- Testing
- Dietary intake of various nutrients, foods and biocompounds
- Where
- United States
- Volunteers
- 3,500 people
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Respiratory Compliance, Functional Residual Capacity
Rescue Antenatal Steroids and Pulmonary Function Tests in Preterm Infants
One course of steroids given to a mother before a premature delivery helps the lungs of the premature infant and decreases breathing problems.
- Conditions
- Respiratory Compliance, Functional Residual Capacity, Pulmonary Function Testing
- Trial name
- NCT00669383
- Testing
- betamethasone
- Where
- United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Fontan Palliation, Congenital Heart Disease
Cardio Pulmonary Exercise Testing in Patients Post the Fontan Palliation in Comparison With Patients With Repaired Congenital Heart Disease and Healthy Volunteers.
prospective cardio respiratory evaluation for patients post the Fontan palliation for single ventricle, compared to subjects post successful cardiac repaired surgery compared to healthy volunteers in order to evaluate the…
- Trial name
- NCT02659462
- Testing
- Cardio Pulmonary Exercise Testing
- Where
- Israel
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Bronchopulmonary Dysplasia, Very Low Birth Weight
Preterm Infant Inhaled Albuterol Dosing
The purpose of this study is to help determine the best dose of inhaled albuterol sulfate in premature babies at risk of developing bronchopulmonary dysplasia (BPD).
- Trial name
- NCT02447250
- Testing
- Varied albuterol dose response
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Oregon Health and Science University
Cystic Fibrosis, CFTR Gene Dysfunction
CFTR Related Pancreatitis Study
The main causes of acute recurrent pancreatitis (ARP) or chronic pancreatitis (CP) in children are defects in genes that have been associated to pancreatitis.
- Trial name
- NCT04274413
- Testing
- Beta Adrenergic Sweat Test
- Sponsor
- The Hospital for Sick Children
Adolescent Idiopathic Scoliosis
The Effect of the Core Stabilization Training on Respiratory Parameters , Functional Capacity and Balance in Scoliosis
The vertebral column is a structure that transfers the weight of the head and torso to the lower extremity, provides trunk movements and protects the spinal cord.A three dimensional deformity involving lateral flexion of the…
- Trial name
- NCT03823053
- Testing
- Home Based Traditional Scoliosis Exercise, Home Based Core Stabilization Training
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Bezmialem Vakif University
Pregnancy Related, Tobacco Smoking
Effects of Prenatal Tobacco Smoke Exposure on Lung Function and Respiratory Epithelium Functionality in Newborns
Despite public campaigns to prevent cigarette smoking, it's about 20% of women who keep on smoking during pregnancy, exposing their fetus to prenatal tobacco adverse effects.
- Conditions
- Pregnancy Related, Tobacco Smoking, Lung Smokers, Newborn
- Trial name
- NCT03047967
- Testing
- lung function tests, Nasal brushing
- Where
- France
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France