Clinical trials: Pulmonary Function Testing
Cystic Fibrosis
Backpack Carrying in Children With Cystic Fibrosis
Cystic Fibrosis is a hereditary, chronic respiratory illness. Cystic Fibrosis leads to a progressive decline in lung function. School-aged children with cystic fibrosis experience backpack carrying everyday.
- Trial name
- NCT02700282
- Testing
- Backpack Carrying
- Where
- France
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Groupe Hospitalier du Havre
Asthma
Effect of an add-on Treatment With Ivy Leaves Dry Extract on Lung Function in Bronchial Asthma
The trial aims to record possible effects of a supplementary treatment with ivy leaves dry extract on different lung function parameter, on bronchial hyperreactivity, on individual markers of asthmatic inflammation and on the…
- Trial name
- HeHe (NCT01692041)
- Testing
- ivy leaves dry extract
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Technische Universität Dresden
Asthma, Pulmonary Function
Vitamin C to Decrease Effects of Smoking in Pregnancy on Infant Lung Function (VCSIP) Longer Term Follow Up
The overall aims of this protocol are to determine whether prenatal supplementation with vitamin C to pregnant smokers can improve pulmonary function at 10 years of age in their offspring.
- Conditions
- Asthma, Pulmonary Function, Wheezing, In Utero Nicotine
- Trial name
- VCSIP (NCT06106646)
- Testing
- No active intervention in this protocol (previously randomized to Vitamin C)
- Where
- 2 sites in United States
- Volunteers
- 225 people
- Sponsor
- Oregon Health and Science University
Bronchopulmonary Dysplasia
Respiratory Oscillometry for the Prediction of Bronchopulmonary Dysplasia
The goal of this observational study is to learn about the correlation between respiratory system reactance, as assessed by respiratory oscillometry, and respiratory outcomes in preterm infants born before 32 weeks of gestation.
- Trial name
- REACT (NCT05986032)
- Testing
- Respiratory Oscillometry
- Where
- 6 sites in Austria, Italy and 3 more
- Volunteers
- 150 people
- Sponsor
- Fondazione IRCCS San Gerardo dei Tintori
Funnel Chest
Functional Capacity of Exercise and Lung Function in Patients Submitted Early Rehabilitation
The aim of this study was to compare the functional capacity of exercise by six-minute walk test and lung function by spirometry, before and after Nuss procedure in subjects who have undergone the early rehabiliation program with…
- Trial name
- NCT02441452
- Testing
- Early rehabilitation
- Volunteers
- 40 people
- Sponsor
- Instituto do Coracao
Pulmonary Langerhans Cell Histiocytosis
Evaluation of Outcome of Adult Pulmonary Langerhans Cell Histiocytosis Based on Lung HRCT and Lung Function
this is a multicenter retrospective study on patients with pulmonary LCH who were sequentially evaluated by concomitant lung HRCT and lung function testing.
- Trial name
- HLP (NCT01651507)
- Where
- France
- Volunteers
- 49 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Congenital Heart Disease, Cardiopulmonary Bypass
Influence of Lung Volume Optimization Maneuver on Cardiac Output and Lung Compliance in Ventilated Children With Congenital Heart Disease Undergoing Surgical Repair
The aim of this randomized interventional multi-center clinical trial is to determine whether a standardized lung volume optimization maneuver (LVOM), including PEEP titration, improves outcomes in children undergoing…
- Conditions
- Congenital Heart Disease, Cardiopulmonary Bypass, Mechanical Ventilation, Peep Titration in Lung Protective Ventilation
- Trial name
- ILOCO-CHD (NCT07486167)
- Testing
- End-expiratory lung volume optimization maneuver with PEEP titration, Standard Care (in control arm)
- Where
- Germany
- Volunteers
- 80 people
- Sponsor
- Charite University, Berlin, Germany
Cystic Fibrosis
Study of Ibuprofen to Preserve Lung Function in Patients With Cystic Fibrosis
OBJECTIVES: I. Determine the effect of different doses of ibuprofen on neutrophil (polymorphonuclear leukocyte; PMN) delivery to a mucosal surface (the oral mucosa) in patients with cystic fibrosis and healthy controls. II.
- Trial name
- NCT00004440
- Testing
- ibuprofen
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- FDA Office of Orphan Products Development
Adolescent Idiopathic Scoliosis
Thoracotomy Effects on Pulmonary Function Test and Chest Expansion
The purpose of the present study was to investigate the effect that corrective surgery for scoliosis would have on pulmonary function as well as the circumference of the chest.
- Trial name
- NCT05803837
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University
Ciliary Motility Disorders, Primary Ciliary Dyskinesia
Genotype/Phenotype Correlation With Focus on Lung Function in Primary Ciliary Dyskinesia (PCD)
Primary Ciliary Dyskinesia (PCD) is a rare genetic disorder characterized by dysfunction of motile cilia associated with recurrent infections of the airways, laterality defects (Situs inversus totalis in about 50% of cases) and…
- Trial name
- LuFu_PCD (NCT04717115)
- Testing
- Genetic diagnosis
- Where
- Germany
- Volunteers
- 1,500 people
- Sponsor
- University Hospital Muenster
Growth Hormone Deficiency
Observational Longitudinal Study in Children Affected by Idiopathic Growth Hormone Deficiency (GHD)
The aim of this study is to assess the developmental patterns of lung function in children affected by growth hormone deficiency after one year of GH therapy.The assessment by specific questionnaires of quality of life and of…
- Trial name
- GHD (NCT02507245)
- Testing
- Growth Hormone-Releasing Hormone
- Volunteers
- 48 people
- Sponsor
- Stefania La Grutta, MD
Asthma in Children
Effect of a Daily Text Reminder on Asthma Medication Use, Symptom Control, and Lung Function in Children
The goal of this clinical trial is to learn if a daily text reminder ("AdhasText") can help children with asthma use their inhalers regularly, control their symptoms, and improve their lung function.
- Trial name
- NCT07053839
- Testing
- Daily Text Reminder
- Where
- Peru
- Volunteers
- 64 people
- Sponsor
- ROXANA AZNARAN TORRES
Primary Ciliary Dyskinesia
Glycine and Magnesium+Thiamine for the Treatment of Primary Ciliary Dyskinesia
Patients with primary ciliary dyskinesia (PCD) have trouble with clearing their bronchi from mucus, which in the long-term may produce severe damage to the lungs.
- Trial name
- NCT06959251
- Testing
- Glycine, Magnesium+thiamine
- Where
- Mexico
- Volunteers
- 60 people
- Sponsor
- Instituto Nacional de Enfermedades Respiratorias
Cystic Fibrosis Related Diabetes, Pancreatic Insufficiency
Pilot and Feasibility Study for the Treatment of Pre-diabetes in Patients With Cystic Fibrosis
The purpose of this study is to provide the necessary data and experience to design a larger, full scale clinical trial to determine if a certain medicine (repaglinide), which increases the amount of insulin secreted by the…
- Trial name
- NCT00763412
- Testing
- repaglinide
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Arbelaez, Ana Maria
Asthma
The Effect of Single Dose Paracetamol on the Lower Airways of Asthmatic and Healthy Children
Asthma is a common inflammatory airway disease. Several researches have demonstrated a possible connection between asthma and exposure to paracetamol.
- Trial name
- NCT01073748
- Testing
- paracetamol
- Where
- Israel
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Respiratory Muscles, Respiration, Artificial
Visualization of Inspiratory Effort and Respiratory Mechanics to Promote Lung- and Diaphragm Protective Ventilation
This is a multicentre prospective cohort trial in adult and pediatric ICU patients. The investigators will measure the effect of a patient's inspiratory effort during mechanical ventilation on the lungs and diaphragm.
- Conditions
- Respiratory Muscles, Respiration, Artificial, Respiratory Function Tests
- Trial name
- VIREM (NCT05459116)
- Testing
- Placement of nasogastric balloon
- Where
- 3 sites in Belgium, Canada
- Volunteers
- 150 people
- Sponsor
- University Hospital, Antwerp
Pulmonary Function Testing
Validation of the STS Device for Pulmonary Function Test in Pediatric Population
This prospective, single-arm, self-controlled validation study aims to evaluate the accuracy and safety of the Spirometry Test System (STS) handheld device in measuring pulmonary parameters in pediatric subjects aged 7-17 years.
- Trial name
- NCT07430709
- Testing
- Spirometry Test System (STS)
- Volunteers
- 160 people
- Sponsor
- Technopulm
Infant, Premature, Diseases, Infant, Newborn, Diseases
Pulmonary Function Using Non-invasive Forced Oscillometry
The purpose of this observational study is to measure pulmonary function in term and preterm infants with and without pulmonary disease including respiratory distress syndrome, bronchopulmonary dysplasia, transient tachypnea of…
- Conditions
- Infant, Premature, Diseases, Infant, Newborn, Diseases, Bronchopulmonary Dysplasia, Respiratory Distress Syndrome, Newborn
- Trial name
- PUFFOR (NCT03346343)
- Testing
- Non-invasive forced airway oscillometry
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Asthma in Children, Asthma
Telemonitoring of Lung Function by Spirometry
Asthma is the most common respiratory disorder in children that causes breathing problems. The patients may have respiratory symptoms such as cough, wheeze, or short of breath.
- Trial name
- NCT04447664
- Testing
- Inclouded telespirometry system
- Where
- Hungary
- Volunteers
- 52 people
- Sponsor
- Szeged University
Wheezing
Nebulized Beclomethasone Dipropionate Improves Respiratory Lung Function in Preschool Children With Recurrent Wheezing
This is a single-centre, open label study, aiming to evaluate the efficacy of beclomethasone dipropionate applied for 12 weeks with a dose of 400 µg twice a day (total dose 800 µg nebulized), on airway resistance and reactances…
- Trial name
- NCT02381158
- Testing
- Nebulized beclomethasone dipropionate
- Volunteers
- 12 people
- Sponsor
- Istituto per la Ricerca e l'Innovazione Biomedica