Clinical trials: Pulmonary Nodules
Pulmonary Nodule, Solitary, Pulmonary Nodule, Multiple
Dynamic Evolution of Pulmonary Nodules and Influence Factors of Its Clinical Decision-making
The researchers are aimed to investigate the dynamic evolution of indeterminate pulmonary nodules by a long-term follow-up of patients with different characteristics.
- Trial name
- DEPICT (NCT04857333)
- Testing
- CT scan, Antibiotics, Surgical Resection
- Where
- China
- Volunteers
- 1,800 people, healthy volunteers welcome
- Sponsor
- GuiBin Qiao
Pulmonary Nodules, Solitary, Pulmonary Nodules, Multiple
AI Assisted Detection of Chest X-Rays
This study has been added as a sub study to the Simulation Training for Emergency Department Imaging 2 study (ClinicalTrials.gov ID NCT05427838).
- Conditions
- Pulmonary Nodules, Solitary, Pulmonary Nodules, Multiple, Pulmonary Consolidation, Pneumothorax
- Trial name
- AID-CXR (NCT06075836)
- Testing
- Cases reading, Ground truthing
- Where
- United Kingdom
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Oxford University Hospitals NHS Trust
Cancer, Metastasis to Lung
Validation of Low Dose CT for Diagnosis of Lung Nodules
The investigators have developed an extremely low dose computed tomography (CT) protocol that on preliminary testing has an effective dose in the range of two chest radiographs.
- Trial name
- NCT03681873
- Testing
- Extremely Low Dose CT
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Benign and Malignant Solitary Pulmonary Nodules
(PET) Imaging in the Management of Patients With Solitary Pulmonary Nodules
All patients with a new, untreated solitary pulmonary nodule (SPN) between 7 mm and 3 cm in diameter identified by chest x-ray, will be approached to undergo positron emission tomography (PET) and computerized tomography (CT).
- Trial name
- NCT00032331
- Testing
- PET Imaging, CT scan
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Pulmonary Nodule, Cohort Study
Respiratory Disease Cohort Studies of Chinese Medicine for Pulmonary Nodule
This study is a prospective multicenter cohort study that primarily evaluates the impact of traditional Chinese medicine treatment on pulmonary nodules
- Conditions
- Pulmonary Nodule, Cohort Study, Traditional Chinese Medicine
- Trial name
- NCT06673121
- Testing
- Traditional Chinese Medicine
- Where
- China
- Volunteers
- 5,000 people
- Sponsor
- Third Affiliated Hospital of Henan University of Traditional Chinese Medicine
Lung Nodules, Pneumothorax Iatrogenic Postprocedural
Pneumothorax Safety of Pleural-Depth-Trimmed Hookwires for Lung Nodule Localization
The goal of this observational study is to learn about the pneumothorax risk associated with the Pleural-Depth-Trimmed Hookwire (PDTH) technique in patients undergoing Preoperative CT-Guided Lung Nodule Localization (POCTGL).
- Conditions
- Lung Nodules, Pneumothorax Iatrogenic Postprocedural, Propensity Score Matching
- Trial name
- NCT07300072
- Testing
- Preoperative CT-Guided Lung Nodule Localization with Pleural-Depth-Trimmed Hookwire (PDTH) Technique, Preoperative CTGuided Lung Nodule Localization with Patent Blue Vital Dye (PBVD) Localization Technique
- Where
- Taiwan
- Volunteers
- 1,072 people
- Sponsor
- Chung Shan Medical University
Lung Tumors
Computed Tomography (CT) in Head and Neck Patients
This study is conducting a comparison of chest x-ray (CXR) and minimum dose thoracic CT (MnDCT) in the detection of lung nodules (metastases) in patients with head and neck carcinoma.
- Trial name
- NCT00188656
- Testing
- CT thorax
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- University Health Network, Toronto
Lung Nodule
Single-lumen Endotracheal Intubation in ENB-guided Localization and Resection of Pulmonary Nodules
The goal of this clinical study is to evaluate the practicality, safety, and feasibility of a 'one-stop' single-lumen (SL) endotracheal intubation strategy for patients undergoing wedge resection of early-stage lung nodules with…
- Trial name
- NCT07288255
- Testing
- Single lumen, single-lumen to double-lumen
- Where
- China
- Volunteers
- 375 people
- Sponsor
- Ruijin Hospital
Tumor of Lung, Pulmonary Nodule
Prospective Study of Serum Marker LncRNA RP5-977B1 in Pulmonary Nodules
Based on previous studies, this project intends to use prospective studies to select patients identified by imaging as pulmonary nodules to explore the potential of RP5-977B1 in differentiating benign and malignant pulmonary…
- Trial name
- NCT06531850
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Affiliated Cancer Hospital & Institute of Guangzhou Medical University
Cryptococcosis, Lung Adenocarcinoma
Derivation and Validation of a Scoring System to Distinguish Cryptococcosis and Adenocarcinoma in Pulmonary Nodules
Pulmonary cryptococcosis often manifests as isolated or multiple nodules, easily mimicking lung cancer clinically and radiologically, which ascribes the poor sensitivity of Cryptococcus culture and rarely positive of Cryptococcal…
- Trial name
- NCT04554875
- Testing
- A scoring system
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Shanghai Pulmonary Hospital, Shanghai, China
Lung Cancer (Diagnosis), Nodule, Solitary Pulmonary
Non-Invasive Malignancy Classifiers Using Blood-Biomarkers for Lung Nodule Evaluation
The goal of the NIMBLE study is to evaluate blood-based biomarkers for lung cancer risk prediction in patients referred with a lung nodule.
- Trial name
- NIMBLE (NCT07623473)
- Testing
- Blood tests
- Where
- Denmark
- Volunteers
- 1,800 people, healthy volunteers welcome
- Sponsor
- Herlev and Gentofte Hospital
Neoplastic Disease, Solid Tumor
Indocyanine Green (ICG) Guided Tumor Resection
This is a study to assess the ability of Indocyanine Green (ICG) to identify neoplastic disease. For many pediatric solid tumors, complete resection of the primary site and/or metastatic deposits is critical for achieving a cure.
- Trial name
- NCT04084067
- Testing
- Indocyanine Green
- Where
- United States
- Volunteers
- 215 people
- Sponsor
- St. Jude Children's Research Hospital
Solitary Pulmonary Nodule, Lung Cancer
Bronchoscopic Approach to the Peripheral Lung Nodule - An Alternative Approach
Patients presenting with solitary or multiple lung nodules often require tissue confirmation in order to guide further management and determine if the lesion is benign or malignant.
- Trial name
- NCT00925210
- Testing
- Sequential pEBUS - ENB
- Where
- 2 sites in Canada
- Volunteers
- 60 people
- Sponsor
- University of Calgary