Clinical trials: Pulp Necrosis
Pulpitis - Irreversible, Pulp Necroses
Lesion Sterilization Tissue Repair and Conventional Pulpectomy in Primary Molars
The aim of this study was to compare the clinical and radiographic success of conventional root canal treatment and lesion sterilisation tissue repair methods in deciduous molars with necrotic or irreversible pulpitis.
- Conditions
- Pulpitis - Irreversible, Pulp Necroses, Root Canal Infection
- Trial name
- NCT06811636
- Testing
- Lesion sterilization and tissue repair, Conventional pulpectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Çanakkale Onsekiz Mart University
Necrotic Pulp, Regenerative Endodontic Procedures
Periapical Bleeding Versus PRF Techniques in Regenerative Endodontic Therapy: A Randomized Controlled Trial
This study investigates a biological approach that allows infected and necrotic teeth to heal themselves instead of being treated with traditional root canal therapy.
- Conditions
- Necrotic Pulp, Regenerative Endodontic Procedures, Mature Teeth, Apical Periodontitis
- Trial name
- NCT06886438
- Testing
- RVS, L-PRF, i-PRF
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Saglik Bilimleri Universitesi
Primary Teeth, Pulp Necroses
Treatment of Infected Pulp in Primary Teeth With a Mixture of Calcium Hydroxide and Gingerols
This study was conducted to evaluate Calcium Hydroxide mixed with Gingerols versus Metapex in treatment of primary teeth with infected necrotic pulp
- Conditions
- Primary Teeth, Pulp Necroses, Infected Pulp, Root Canal Treatment
- Trial name
- NCT05181813
- Testing
- Ginge-Cal, Metapex
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Necrotic Pulp
Pulp Revascularization Versus MTA Apexification
This study compared the efficiency of pulp revascularization and MTA apexification in the treatment of patients with necrotic immature anterior teeth.
- Trial name
- RCT (NCT03083015)
- Testing
- revascularization, Apexification
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Enas Ebrahim Sayed
Pulp Necrosis, Apexification
Evaluation the Effect of Using of Apical Matrix With Apexification Procedure on Apical Healing of Necrotic Immature Teeth
This study was conducted to evaluate the effect of the use of apical matrix, with Mineral Trioxide Aggregate (MTA) or calcium hydroxide Ca(OH)2 Apexification on apical healing and calcific barrier formation of immature teeth with…
- Trial name
- NCT03849222
- Testing
- Apexification, MTA, Ca(OH)2
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Regenerative Endodontics in Traumatized Immature Teeth
Regenerative Treatment of Traumatized Immature Permanent Incisors With Pulp Necrosis
Endodontic management of traumatized immature permanent teeth with pulp necrosis is both a clinical challenge for the dental practitioners and a public health care problem.
- Trial name
- NCT04000854
- Testing
- Calcium hydroxide (Calacept)
- Where
- Sweden
- Volunteers
- 180 people
- Sponsor
- Karolinska Institutet
Pulp Disease, Dental, Pulp Mummification
Lasers as an Alternative to Formocresol and Sodium Hypochlorite Medicaments in Pulpotomy Techniques
The goal of this clinical trial is to evaluate the dental lasers as an alternative of chemical medicaments used in the pulpotomy procedures.
- Trial name
- NCT06002646
- Testing
- Formocresol, Sodium Hypochlorite Solution, Diode laser
- Where
- Iraq
- Volunteers
- 60 people
- Sponsor
- University of Sulaimani
Dental Pulp Necrosis, Disorder of Tooth Development
A Clinical Study to Compare Two Revascularization Protocols to Treat Non-vital Teeth With Incomplete Root Formation
Both methods tested in this study disinfect the non-vital root canals and induce blood clot formation inside the root canal. One method places calcium hydroxide inside the root canal after disinfection and the blood clot is…
- Trial name
- NCT01827098
- Testing
- Endodontic Regeneration
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- University of Michigan
Dental Pulp Necrosis
Assessment of a New Apexification Method for Patients Presenting a Non Vital Immature Tooth
Pulp necrosis is one of the main complication of dental trauma. When it happens on an immature tooth, pulp necrosis implies a lack of root maturation and apical closure.
- Trial name
- APEXMTA (NCT00472173)
- Testing
- Mineral Trioxide Aggregate, Calcium hydroxide
- Where
- France
- Volunteers
- 34 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Dental Pulp Necrosis, Periapical Abscess
Efficiency of Triple Antibiotic Paste, Ciprofloxacin/Propolis, Ciprofloxacin/Metronidazole, Propolis/Metronidazole Combinations on Revascularization Process of Immature Necrotic Maxillary Incisors of Patients 8-18 Years Old.
This Study Was Made to Evaluate the Antibacterial Effect of Different Antibacterial Combinations on Revascularization Process in Permanent Anterior Immature Teeth.
- Conditions
- Dental Pulp Necrosis, Periapical Abscess, Root Canal Infection
- Trial name
- NCT03533231
- Testing
- Canal Disinfection Triple Antibiotic Paste (TAP), Ciprofloxacin + Propolis Paste, Ciprofloxacin + Metronidazole Paste
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Tariq Yehia
Pulp Necroses
Assessment of Post-operative Pain After Different Instrumentation Techniques in Pulpectomy Treatment of Primary Molars
The goal of this clinical trial is to compare the post operative pain after using three different instrumentation techniques in pulpectomy treatment of pediatric participant.
- Trial name
- NCT06256250
- Testing
- pulpectomy treatment will be done using the adaptive xp endo shaper., pulpectomy treatment will be done using FANTA AF baby files., pulpectomy treatment will be done using hand k files.
- Where
- Egypt
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Pulp Necrosis, Periapical Lesion
Success Rate of Single Versus Two Visit Regenerative Treatment Protocol in Non Vital Mature Anterior Teeth
This study evaluates success rate of non vital mature anterior teeth with periapical lesion treated by regenerative endodontic protocol in single visit versus two visit technique.
- Conditions
- Pulp Necrosis, Periapical Lesion, Anterior Teeth
- Trial name
- NCT03717337
- Testing
- Single visit pulp regeneration, Two visit pulp regeneration
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Periapical Periodontitis
Periapical Healing After One or Two-visits to Endodontic Treatment in Adolescents Patients
The main objective of this study is the prevention and repair of apical periodontitis in lower molars with pulp necrosis after the execution of endodontic treatment in one or two visits in adolescent patients.
- Trial name
- PHAP (NCT01312194)
- Testing
- Root canal therapy in one visit, Root Canal Therapy in two-vist
- Where
- Brazil
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio de Janeiro
Necrotic Pulp
Concentrated Growth Factor Versus Platelet Rich Fibrin in Revitalization of Necrotic Young Permanent Incisors
Regenerative endodontic procedures (REPs) are the most recent proposal to manage immature permanent teeth with necrotic pulps. So in this study, the investigator will evaluate the clinical and radiographical revitalization…
- Trial name
- NCT05522270
- Testing
- revitalization by concentrated growth factor
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ahmad Elheeny
Necrotic Pulp
Bacterial Reduction of Rotary Versus Manual Filing System Using Different Irrigants in Primary Molars
This study will evaluate and compare the microbial efficacy of rotary and manual filing system using Neem extract, NaOCL and saline .
- Trial name
- NCT06418386
- Testing
- manual saline IA, manual neem IB, manual sodium hypochlorite IC
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Pulp Necrosis
Tissue Characterization in Teeth Treated With a Regeneration Protocol
The purpose of the investigators study is to characterize the composition of the hard and soft tissues present in root canals of teeth previously diagnosed with necrotic pulps and incomplete root formation and treated with a…
- Trial name
- NCT00881907
- Testing
- Triple Antibiotic Paste
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Pulp Disease, Dental, Pulp Necrosis
Chloramphenicol, Tetracycline, Zinc Oxide and Eugenol Paste (CTZ Paste) for Emergency Dental Treatment in Public Health Settings: A Randomized Trial
The treatment of pulpal diseases in primary teeth represents a significant challenge in public health, particularly in emergency dental care settings, where factors such as limited clinical time, low child cooperation, and…
- Conditions
- Pulp Disease, Dental, Pulp Necrosis, Pulp Therapy in Primary Molars, Primary Teeth
- Trial name
- CTZ- emergency (NCT07542639)
- Testing
- CTZ Paste, ZOE Pulpectomy
- Volunteers
- 110 people
- Sponsor
- University of Sao Paulo
Dental Pulp Necrosis, Permanent Incisor Avulsed by Trauma
Revitalization of Immature Permanent Teeth With Necrotic Pulps Using SHED Cells
Revitalization of Young Immature Permanent Teeth With Necrotic Pulps Using Autologous Stem Cells from Human Exfoliated Deciduous Teeth
- Trial name
- NCT01814436
- Testing
- scaffold-free SHED-derived pellet
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Air Force Military Medical University, China
Pulp Necrosis
Photo-Activated Disinfection Versus Triple-Antibiotic Paste for Management of Necrotic Young Permanent Anterior Teeth
This study aims to compare regenerative endodontics for necrotic young permanent anterior teeth using oral photo-activated disinfection versus triple antibiotic paste in terms of: 1.
- Trial name
- NCT03763110
- Testing
- Photo Activated Disinfection, antibiotic paste
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pulp Necrosis
Effectiveness of Regenerative Endodontics Therapy for Single-rooted Mature Permanent Tooth With Pulp Necrosis
This study is to evaluate the effectiveness of regenerative endodontics therapy in single-rooted permanent teeth with pulp necrosis，and compare the clinical efficacy of platelet rich fibrin (PRF) and blood clot (BC) as scaffolds.
- Trial name
- NCT04313010
- Testing
- PRF, BC
- Where
- 3 sites in China
- Volunteers
- 346 people
- Sponsor
- Southern Medical University, China