Clinical trials: Pulpitis
Irreversible Pulpitis, Deep Caries
TheraCal LC Coronal Pulpotomy and MTA Coronal Pulpotomy in Mature Permanent Molars
To evaluate and compare the clinical and radiographic success rate of TheraCal LC and MTA for coronal pulpotomy of mature permanent molar in 9-14 year children.
- Trial name
- NCT05733468
- Testing
- Theracal LC, MTA
- Where
- India
- Volunteers
- 72 people
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Pulpitis - Irreversible
Assessing Success of MTA and Pre-mixed Bioceramic in Mature Teeth With Irreversible Pulpitis With Full Pulpotomy.
Although many pulpotomy agents are commercially available, there is a dearth of clinical research comparing the efficacy of these agents in treating individuals with irreversible pulpitis.
- Trial name
- GCP (NCT05853185)
- Testing
- Pro Root MTA®, EBRRM®
- Where
- Pakistan
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Liaquat University of Medical & Health Sciences
Pulpitis - Irreversible
Efficacy of Combination of Biodentine and Simvastatin as a Pulp Capping Materials in Vital Pulpotomy of Primary Molars
Objective: This study was conducted to evaluate the efficacy of combination of biodentine with simvastatin as a pulpotomy agent for vital primary molars clinically and radiographically.
- Trial name
- NCT05582317
- Testing
- Biodentine, Simvastatin
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Suez Canal University
Pulpitis, Dental Pulp Diseases
Intentional Pulpotomy to Preserve Hopeless Molars
When proximal carious lesions of primary molars are located in close proximity to the cementum enamel junction (CEJ), marginal seal is challenging and extraction is recommended.
- Conditions
- Pulpitis, Dental Pulp Diseases, Tooth Diseases
- Trial name
- NCT04385693
- Testing
- Pulpotomy, Extraction and placement of space maintainer
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of Florida
Pulpitis
The Use of Platelet-Rich Fibrin in Partial Pulpotomy Procedure
The aim of this study is to evaluate the clinical and histological pulp responses when MTA and a combined of MTA/PRF is used as pulp-capping agents after partial pulpotomy.
- Trial name
- NCT04331964
- Testing
- partial pulpotomy
- Where
- Syria
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Damascus University
Dental Caries
Biodentine Pulpotomy vs Metapex Pulpectomy in Primary Molars: Clinical & Radiographic Comparison of Outcomes in Irreversible Pulpitis Cases
Irreversible pulpitis is defined as a clinical diagnostic based on subjective and objective findings suggesting that the vital inflamed pulp is incapable of healing in the American Association of Endodontists (AAE) Consensus…
- Trial name
- NCT06524921
- Testing
- dental pulpectomy using metapex, dental pulpotomy using biodentine
- Where
- Egypt
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Mohamed Ahmed Hamdi Abo El Yamin
Pulpitis Reversible, Pulp Exposure, Dental
Pomegranate Peel Extract for Primary Molar Pulpotomy
Pomegranate peel extract has demonstrated a range of potential uses in the biomedical industry in recent years because of its numerous benefits, which include anti-inflammatory, antibacterial, anti-apoptotic, antioxidant, and…
- Trial name
- NCT07108738
- Testing
- Pulpotomy, Radiation
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Tanta University
Pulpitis - Irreversible
Pulpotomy vs Root Canal Treatment for Teeth With Symptomatic Irreversible Pulpitis
This study is a randomised controlled trial for complete pulpotomy as an alternative to root canal treatment for teeth with clinical diagnosis of symptomatic irreversible pulpitis (i.e.
- Trial name
- NCT05964933
- Testing
- Complete Pulpotomy, Pulpectomy and Root Canal Treatment
- Where
- Singapore
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Pulpectomy, Primary Teeth Indicated for Pulp Therapy
Comparative Evaluation of Pediatric Rotary Files and Hand Files in Primary Molars
The goal of this clinical trial is to evaluate and compare the efficacy of Kedo-Nano Plus rotary files, Kedo-S Square rotary files, and manual K-files for biomechanical preparation during pulpectomy of primary mandibular molars…
- Conditions
- Pulpectomy, Primary Teeth Indicated for Pulp Therapy, Mandibular Molar Teeth With Symptomatic Irreversible Pulpitis
- Trial name
- NCT07702877
- Testing
- Pulpectomy, Kedo-S Square rotary file, Manual K files
- Where
- India
- Volunteers
- 60 people
- Sponsor
- Goa Dental College
Reversible Pulpitis, Dental Caries
Effect of Hemostatic Agents on TheraCal PT Pulpotomy Success in Primary Molars
Dental caries in primary teeth can sometimes lead to inflammation of the dental pulp, the soft tissue inside the tooth. When the pulp remains capable of healing, pulpotomy may be performed to preserve the tooth until its natural…
- Conditions
- Reversible Pulpitis, Dental Caries, Primary Molar Pulpotomy, Dental Pulp Exposure
- Trial name
- CEHA-TP RCT (NCT07876934)
- Testing
- 2.5% Sodium Hypochlorite applied to pulpal tissue/stumps for 3 minutes to achieve hemostasis prior to TheraCal PT placement during primary molar pulpotomy and 15% Ferric Sulfate (Astringedent™ 15.5%)
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Reem Mohamed Gaber
Reversible Pulpitis
TheraCal PT vs. Formocresol in Primary Molar Pulpotomies
This prospective, randomized, parallel-group clinical trial evaluated the 12-month clinical and radiographic success rates of TheraCal PT versus formocresol in primary molar vital pulpotomies among 50 children aged 5 to 8 years.
- Trial name
- NCT07864181
- Testing
- Dual cured resin modified
- Where
- Syria
- Volunteers
- 50 people
- Sponsor
- Hama University
Reversible Pulpitis
Direct Pulp Capping With MTA and Calcium Hydroxide.
Aim of the study was to evaluate and compare clinical and radiographic success with MTA and calcium hydroxide as direct pulp capping materials in cariously exposed mandibular molars.
- Trial name
- NCT03284697
- Testing
- Direct Pulp Capping with Ca(OH)2, Direct Pulp Capping With MTA
- Volunteers
- 64 people
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Pulpitis in Permanent Teeth, Dental Caries Extending to Pulp
Pulp Inflammatory Markers and Outcome of Pulpotomy
This is a prospective clinical study that aims to investigate the level of inflammatory mediators in the inflamed dental pulp and its potential relationship to the outcome of full pulpotomy in mature permanent teeth with carious…
- Trial name
- pulpitis (NCT06960603)
- Testing
- Full pulpotomy
- Where
- Jordan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
Pulpitis - Irreversible
Effect of Cryotherapy on Postoperative Pain in Vital Pulp Treatment of Molar Teeth
The goal of this clinical trial was to evaluate the effect of cryotherapy with salin solution on the intensity of postoperative pain after total pulpotomy procedures in molar teeth with symptomatic irreversible pulpitis.
- Trial name
- NCT06644703
- Testing
- Cryotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- Cukurova University
Pulpitis - Irreversible, Tooth Decay
Efficacy of PRF and MTA as Compared to Calcium Hydroxide for Pulpotomy in Human Irreversibly Inflamed Permanent Teeth
Of all the various pulpotomy medicaments that have been studied till to date, three agents have been selected for this study to compare their efficacy.
- Trial name
- NCT05266859
- Testing
- Calcium hydroxide, MTA, PRF
- Where
- Pakistan
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Liaquat College of Medicine and Dentistry
Pain, Postoperative, Irreversible Pulpitis
Comparison of Nitrofurantoin and Calcium Hydroxide as Intracanal Medicaments in Alleviating Post-operative Pain
Intracanal medicaments have been frequently used in patients with endodontic and periradicular infection for the elimination of microorganisms.
- Trial name
- NCT04900571
- Testing
- Nitrofurantoin 100 MG
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Altamash Institute of Dental Medicine
Symptomatic Reversible Pulpitis (Disorder)
The Effect of Different Treatment Methods on the Apical Closure and Treatment Success in Permanent First Molars
The purpose of this thesis study is to evaluate the clinical and radiographic success of direct capping and pulpotomy applications using ProRoot MTA (mineral trioxide aggregate) in lower permanent first molars with reversible…
- Trial name
- NCT06575062
- Testing
- Direct Pulp Capping with ProRoot MTA, Pulpotomy with ProRoot MTA
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Pulpitis - Irreversible
Pulpotomy vs Root Canal Treatment for Teeth With Symptomatic Irreversible Pulpitis
high-quality evidence is needed to add to current knowledge and also assess the long-term outcomes for full/complete pulpotomy after carious pulpal exposure in patients with signs and symptoms indicative of irreversible pulpitis
- Trial name
- NCT05726357
- Testing
- vital pulp therapy
- Where
- Egypt
- Volunteers
- 380 people, healthy volunteers welcome
- Sponsor
- British University In Egypt
Pulpitis - Irreversible, Ozone
Zinc Oxide Ozonated Olive Oil in LSTR
This study will be carried out to evaluate and compare the clinical and radiographic effect of zinc oxide-ozonated olive oil (ZnO-OO) versus Modified Triple Antibiotic Paste (MTAP) as a Lesion Sterilization and Tissue Repair…
- Conditions
- Pulpitis - Irreversible, Ozone, Pulp Disease, Dental, Primary Teeth
- Trial name
- Zn-OO/MTAP (NCT06854744)
- Testing
- lesion sterlization and tissue repair, Zinc Oxide Ozonated Oil, Modified Triple Antibiotic Paste
- Where
- 2 sites in Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Tanta University
Irreversible Pulpitis
Epigallocatechin Gallate (EGCG) as a Flushing Agent During Full Pulpotomy in Mature Permanent Molars With Irreversible Pulpitis
This study evaluates the effect of two flushing agents (epigallocatechin gallate (EGCG) and sodium hypochlorite (NaOCl)) during full pulpotomy using two different calcium silicate-based materials (MTA and premixed bioceramic…
- Trial name
- NCT05811403
- Testing
- Epigallocatechin gallate (EGCG), Sodium hypochlorite (NaOCl), Mineral trioxide aggregate (MTA)
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- Cairo University