Clinical trials: Quadriceps
Anterior Cruciate Ligament Injuries
Operant Conditioning After ACL Reconstruction
The purpose of this study is to examine if the changes in corticospinal function that accompany ACL reconstruction can be improved through a form of mental coaching and encouragement, known as operant conditioning.
- Trial name
- NCT05519345
- Testing
- Operant Conditioning, Control
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of Michigan
Acute Injury of Anterior Cruciate Ligament
Comparative Study of Anterior Cruciate Ligament Reconstruction (Quadriceps Versus Hamstring Tendon)
The purpose of this randomized study is to compare clinical and functional outcomes of both surgery techniques for anterior cruciate ligament reconstruction (using quadriceps tendon versus hamstring tendon) after reconstruction…
- Trial name
- NCT02832791
- Testing
- QUADRICEPS TENDON, HAMSTRING TENDON
- Where
- Spain
- Volunteers
- 55 people
- Sponsor
- Universidad de Granada
Tear of Fibrocartilage of Joint
Neuromuscular Consequences of Knee Arthroscopy
To determine changes in quadriceps muscle function following the application of ice and compression to the knee.
- Trial name
- NCT01786772
- Testing
- Cryotherapy and compression, Cryotherapy
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Creighton University
Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture
Tendon-Bone Versus All-Soft-Tissue for ACL Reconstruction: A Patient-Blinded Randomized Clinical Trial
In primary pediatric Anterior cruciate ligament (ACL) reconstruction, the quadriceps tendon with either tendon and patellar bone or an all-tendon graft is commonly employed.
- Conditions
- Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture, Anterior Cruciate Ligament Tear
- Trial name
- NCT04039971
- Testing
- ACL Reconstruction
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Colorado, Denver
Chronic Obstructive Pulmonary Disease
Comparison of Repetitive Magnetic Stimulation and Exercise on Quadriceps Function in COPD
Background Chronic Obstructive Pulmonary Disease (COPD) patients develop leg weakness and a reduced walking capacity, due to reduced leg muscle oxygen-utilising capacity (OUC).
- Trial name
- NCT00737698
- Testing
- Exercise, Repetitive magnetic stimulation
- Where
- United Kingdom
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Amputation, Traumatic
Rectus Femoris Thickness Measurement in Unilateral Transtibial Amputated Prosthesis Users
Knee extension strengthening is one of the cornerstones of rehabilitation in prosthesis users with transtibial amputation. It is recommended in terms of increasing functional mobility, preventing the risk of fall and knee…
- Trial name
- NCT04262297
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Marmara University
Cystic Fibrosis
Sit-to-stand Test in Cystic Fibrosis Children and Adolescents
Cystic fibrosis (CF) is a chronic hereditary respiratory disease. Exercise testing is part of CF patients regular assessment. Cardio-Pulmonary Exercise Testing (CPET) is currently considered as the gold standard to assess…
- Trial name
- NCT03069625
- Testing
- Sit-to-stand test, 6-Minute Walk Test
- Where
- 3 sites in France
- Volunteers
- 36 people
- Sponsor
- Groupe Hospitalier du Havre
Anterior Cruciate Ligament Injury, Quadriceps Dysfunction
Exercise Loading Biology Post-Traumatic OsteoArthritis Study - a Pilot and Feasibility Study
FROM RISK FACTORS TO THE PREVENTION OF LONG-TERM CONSEQUENCES AFTER CRUCIATE LIGAMENT INJURY (ACL injury) - This is a research project where we seek new knowledge about why some people have a high risk and others a low risk of…
- Conditions
- Anterior Cruciate Ligament Injury, Quadriceps Dysfunction, Knee Joint Loading, Anterior Cruciate Ligament Reconstruction
- Trial name
- ExeLoadBioPTOA (NCT06892899)
- Where
- Norway
- Volunteers
- 40 people
- Sponsor
- May Arna Risberg
Neck of Femur Fracture
PENG Versus Femoral Nerve Block in Neck of Femur Fracture
Neck of femur (NOF) fracture is a common presentation to the emergency department, particularly in our older population. NOF fracture is associated with a high social and economic cost with significant effects on patients'…
- Trial name
- NCT05002725
- Testing
- Lidocain
- Where
- Ireland
- Volunteers
- 64 people
- Sponsor
- University College Cork
Autografts, Blood Flow Restriction Therapy
Blood Flow Restriction Following ACLR w/Quad Autograft
This project is intended to acquire objective measurements of implementing BFR rehabilitation in ACL reconstructions to show any changes upon completion of the BFR protocol.
- Conditions
- Autografts, Blood Flow Restriction Therapy, Rehabilitation Outcome, Quadriceps Muscle Strength
- Trial name
- BFR Quad Delay (NCT06636045)
- Testing
- Not applicable- observational study
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Kansas Medical Center
Emphysema
Analysing Peripheral Skeletal Muscle Function Before and After Endobronchial Valve Treatment
Rationale: Chronic obstructive pulmonary disease (COPD) is characterised by a high prevalence of peripheral muscle dysfunction, which can have significant clinical consequences, including decreased exercise capacity, reduced…
- Trial name
- ENDURANCE (NCT06025500)
- Testing
- 31P-Magnetic Resonance Spectroscopy (31P-MRS)
- Where
- Netherlands
- Volunteers
- 15 people
- Sponsor
- University Medical Center Groningen
Anterior Cruciate Ligament Rupture
Reconstruction of the ACL With QT Graft With Bone Plug vs BPTB
Background: Anterior cruciate ligament (ACL) injury is one of the most common orthopedic injuries worldwide. Currently, the use of the bone patellar tendon bone graft (BPTB) technique is considered the gold standard.
- Trial name
- NCT06189573
- Testing
- Anterior cruciate ligament Reconstruction with autologous quadriceps tendon graft, Anterior cruciate ligament Reconstruction with autologous bone patellar tendon bone graft
- Where
- Mexico
- Volunteers
- 80 people
- Sponsor
- Instituto Nacional de Rehabilitacion
COPD - Chronic Obstructive Pulmonary Disease, Muscle Atrophy
Progressive Resistance Training of the Extensor Muscle of the Thigh in COPD-patients Hospitalized With an Exacerbation
We want to test the hypothesis, that resistance training by the use of weigth cuffs on the angle can prevent loss or improve the strength of the quadriceps muscle in COPD patients admitted to hospital due to an exacerbation.
- Trial name
- NCT01812460
- Testing
- Intervention-training-group
- Where
- Denmark
- Sponsor
- Frederikssunds Hospital, Denmark
Osteoarthritis, Knee, Anterior Cruciate Ligament Injuries
Vibration and Post-traumatic Osteoarthritis Risk Following ACL Injury
The goal of this randomized clinical trial is to evaluate the effects of vibration on factors related to the risks of post-traumatic knee osteoarthritis and secondary anterior cruciate ligament (ACL) injury in individuals who…
- Conditions
- Osteoarthritis, Knee, Anterior Cruciate Ligament Injuries, Post-traumatic Osteoarthritis, Quadriceps Muscle Atrophy
- Trial name
- NCT04875052
- Testing
- Experimental: Whole Body Vibration, Experimental: Local Muscle Vibration, Standard ACL Rehabilitation
- Where
- 2 sites in United States
- Volunteers
- 114 people
- Sponsor
- University of North Carolina, Chapel Hill
Muscle Fatigue
Characterization of Hamstring and Quadriceps Neuromuscular Fatigue After Consecutive Soccer Trainings in Soccer Players
This is a monocentric study assessing hamstring and quadriceps neuromuscular fatigue after 3 consecutive soccer trainings. The purpose of this study was: 1.
- Trial name
- QIF2 (NCT07861269)
- Testing
- a simulated soccer training
- Volunteers
- 20 people
- Sponsor
- University Hospital, Strasbourg, France
Post ACL Reconstruction
Rate of Force Development vs Isometric Strength of Quadriceps
Peak isometric strength of quadriceps (QI) has been used to help determine an athletes ability to safely return back to sport following an anterior cruciate ligament (ACL) reconstruction surgery.
- Trial name
- NCT04005274
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Kaiser Permanente
Hereditary Inclusion Body Myopathy, GNE Myopathy
GNE-Myopathy Disease Monitoring Program (GNEM-DMP): A Registry and Prospective Observational Natural History Study to Assess GNE Myopathy or Hereditary Inclusion Body Myopathy (HIBM)
HIBM is a severe progressive myopathy that typically presents in early adulthood as weakness in the distal muscles of the lower extremities and progresses proximally, leading to a loss of muscle strength and function, and…
- Conditions
- Hereditary Inclusion Body Myopathy, GNE Myopathy, Nonaka Disease, Quadriceps Sparing Myopathy (QSM)
- Trial name
- NCT01784679
- Where
- 5 sites in United States, Bulgaria and 3 more
- Volunteers
- 319 people
- Sponsor
- Ultragenyx Pharmaceutical Inc
ACL Tear
Quadriceps Strengthening ACL Reconstruction
The purpose of this study is to characterize quadriceps function and squat biomechanics during the early strengthening phase in adolescent patients undergoing a standardized combined neuromuscular electrical stimulation (NMES)…
- Trial name
- ACL (NCT07015541)
- Testing
- NMES and BFR, Standard physical therapy
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Stanford University
ACL Injury
BFR Therapy for Post-Op Rehab of ACL Reconstruction With Quadriceps Tendon Autograft
The overall objective of the proposed research is to conduct a prospective, randomized controlled trial to investigate whether the addition of BFR therapy to standard post-operative rehabilitation regimen significantly improves…
- Trial name
- NCT04519801
- Testing
- Blood Flow Restriction (BFR) therapy, Standard REHAB
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Brooke Army Medical Center
Anterior Cruciate Ligament Injuries, Knee Injuries
Graft Type and Outcomes After ACL Reconstruction in Female Athletes
This prospective multicenter cohort study aims to compare clinical and functional outcomes between hamstring tendon and quadriceps tendon autografts in anterior cruciate ligament (ACL) reconstruction in female athletes.
- Trial name
- LCA-WOMEN (NCT07722104)
- Testing
- Hamstring tendon autograft ACL reconstruction, Quadriceps tendon autograft ACL reconstruction
- Where
- Spain
- Volunteers
- 82 people
- Sponsor
- Universidad Católica San Antonio de Murcia