Clinical trials: Radiation Exposure
Head Trauma
Infant Minor Head Trauma Clinical Decision Rule
The purpose of this study is to validate a clinical decision rule for the management of minor head trauma in infants aged less than two years, constructed with the intention of minimizing the rate of computed tomography scans…
- Trial name
- PELICAN (NCT03050970)
- Where
- France
- Volunteers
- 8,802 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Healthy
Positron Emission Tomography Imaging of Dopamine Receptors Using the Tracer [11C]NNC-112
This study will investigate the use of [11C]NNC-112 in positron emission tomography (PET) scanning. PET is a technique that uses radioactive isotopes called tracers to provide images of the brain.
- Trial name
- NCT00088517
- Testing
- [11C]NNC-112
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Coronary Artery Disease
Combined Supine/Prone Acquisitions in Stress-First/Stress-Only Myocardial Perfusion Imaging to Reduce Equivocal Results
Participants are being asked to participate in this research study because the participant's doctor has ordered a myocardial perfusion SPECT (Single-Photon Emission Computed Tomography) scan to look at the blood flow in the…
- Trial name
- SFSO-MPI (NCT02576886)
- Testing
- Gamma Camera, Prone Imaging
- Where
- Canada
- Volunteers
- 490 people, healthy volunteers welcome
- Sponsor
- Hamilton Health Sciences Corporation
Hearing Loss
Hearing Loss and Complaint in Patients With Head and Neck Cancer Treated With Radiotherapy
Hypothesis: Treatment for head and neck tumors often involve methods that affect the auditory system and cause hearing loss. Neck dissection negatively impacts the lymphatic drainage, chemotherapy uses ototoxic drugs…
- Trial name
- NCT01102621
- Where
- Brazil
- Volunteers
- 282 people, healthy volunteers welcome
- Sponsor
- Hospital A.C. Camargo
Bone Diseases
Use of a Radiopaque Localizer Grid and Methylene Blue Staining as an Aid to Reduce Radiation Exposure
Localization of small femur lesions for resection can be challenging and may be associated with the need for significant fluoroscopic imaging and tissue dissection.
- Trial name
- NCT02969005
- Testing
- surgical treatment
- Volunteers
- 40 people
- Sponsor
- Children's Hospital of Chongqing Medical University
Glioblastoma (GBM), DIPG
Prolonged Exposure to Doxorubicin in Patients With Glioblastoma Multiforme and Diffuse Intrinsic Pontine Glioma
The standard therapy of glioblastoma (GBM) consists of gross total resection followed by focal irradiation to the tumor bed with concomitant and adjuvant temozolomide (TMZ).
- Conditions
- Glioblastoma (GBM), DIPG, Brainstem Glioma, Pediatric, Diffuse Spinal Glioma
- Trial name
- NCT02758366
- Testing
- Doxorubicin
- Where
- Italy
- Volunteers
- 21 people
- Sponsor
- Meyer Children's Hospital IRCCS
Scoliosis, Spinal Curvatures
Using Radiation-free Ultrasound for Screening Scoliosis Among Female School Children in Hong Kong to Reduce Unnecessary X-ray Exposure
In the scoliosis screening program of the Student Health Service (SHS), Department of Health (DH), in Hong Kong, more than 50% of screened school children prescribed with x-ray examination basing on the screening protocol did not…
- Conditions
- Scoliosis, Spinal Curvatures, Spinal Diseases, Bone Diseases
- Trial name
- SScoE (NCT06828068)
- Testing
- Ultrasound (Scolioscan system), and EOS radiography system
- Where
- Hong Kong
- Volunteers
- 442 people
- Sponsor
- Chinese University of Hong Kong
Keratoconus
Evaluation of Topical Riboflavin Exposed to UVA Radiation and Implantation of Corneal Ring
The purpose of this study is to postpone the corneal transplantation in keratoconus and promote the stiffness of the cornea across the riboflavin-UVA corneal collagen crosslinking , and after, corneal ring surgery.
- Trial name
- NCT00832897
- Testing
- Corneal collagen crosslinking
- Where
- Brazil
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Cholangiopancreatography, Endoscopic Retrograde, Occupational Exposure
Radiation Exposure During Endoscopic Retrograde Cholangiopancreatography
Radiation now becomes a dreadful effect as its outcomes are tremendous to be expected. As a result, anesthetists become an inevitable target to the radiation exposure since they have to monitor patients closely during the…
- Conditions
- Cholangiopancreatography, Endoscopic Retrograde, Occupational Exposure, Radiation Injuries
- Trial name
- NCT02985164
- Testing
- PDSa, PDSb
- Volunteers
- 222 people
- Sponsor
- Siriraj Hospital
Enteral Feeding Intolerance
Optimal Feeding Tube Placement
A randomized controlled trial comparing current standard blind method to CORTRAK enteral access system (CEAS), an FDA approved electromagnetic device to place enteric tubes.
- Trial name
- NCT04241146
- Testing
- Enteric Tube, CORTRAK enteral access system
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Gene Mutation-Related Cancer, Esophageal Cancer
Genomic Study of Relapse Esophageal Cancer After Radiotherapy
Radiotherapy plays an important role in multidisciplinary treatment of esophageal cancer. However, about half patients received radiotherapy occurred relapse. Once relapse occurred, there is no better treatment strategy.
- Conditions
- Gene Mutation-Related Cancer, Esophageal Cancer, Radiation Exposure
- Trial name
- NCT04694391
- Testing
- whole exome sequence
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Fudan University
Intracranial Aneurysms
CARE: A Prospective Multicenter Case Study to Assess Radiation Exposure in Patients Treated With the Penumbra Coil 400
The primary objective of this study is to gather data on the radiation exposure in patients treated with the Penumbra Coil 400™ System (PC 400) or conventional coils per their respective indications for use.This is a multicenter…
- Trial name
- CARE (NCT02122133)
- Testing
- PC 400
- Where
- United States
- Volunteers
- 67 people
- Sponsor
- Penumbra Inc.
Radiation Injuries, Xerostomia
Structure and Functional Status of Parotid Glands Exposed to Therapeutic Irradiation
Therapeutic irradiation to the head and neck for cancer damages salivary glands present in the radiation field. Despite long recognition of radiation-induced salivary hypofunction, and the associated oral morbidities, the…
- Trial name
- NCT00001523
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Ionizing Radiation Exposure, Quality Improvement
CT DOSE Collaboratory
This is a pragmatic stepped-wedge cluster randomized controlled trial to explore variation in doses used for diagnostic CT by pooling radiation dose data across diverse healthcare delivery systems.
- Trial name
- NCT03000751
- Testing
- Simple Audit Report, Multi-Component Intervention, In-Person Meeting
- Volunteers
- 864,080 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Diabetes
Dexcom G6 for Total Pancreatectomy With Islet Autotransplantation (TPIAT) Patients
A single-center prospective trial on the effects of standard of care radiation exposure on the Dexcom G6 continuous glucose monitoring (CGM) device.
- Trial name
- NCT05607576
- Testing
- Uncovered CGM during radiologic procedures
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Deborah Elder
Non-hodgkin Lymphoma, Hodgkin Lymphoma
Chemoradiotherapy With Targeted Immunotherapy in Pediatric Lymphoma
The addition of targeted immunotherapy will be safe and well tolerated and facilitate the reduction of anthracycline exposure while preserving lymphoma disease control in children, adolescents and young adults (CAYA) with mature…
- Trial name
- RADICAL (NCT05253495)
- Testing
- DOC Group B, Pv-COMRAD 1 and 2 Group B, Pv-R-CYM 1 and 2 Group B
- Where
- 3 sites in United States
- Volunteers
- 80 people
- Sponsor
- New York Medical College
Computed Tomography, Carcinogenesis
CT Carcinogenic Risk in Patients With Appendicitis
The purpose of this study is to compare the incidence rate of leukemia between CT-exposed and CT-unexposed group in patients who underwent appendectomy in South Korea.
- Conditions
- Computed Tomography, Carcinogenesis, Radiation Exposure, Appendicitis
- Trial name
- NCT03776435
- Testing
- Abdomen CT
- Where
- South Korea
- Volunteers
- 1,000,000 people
- Sponsor
- Seoul National University Bundang Hospital
Radiation Exposure
Reference Dose Levels During Fluoroscopically Guided Procedures in Operating Rooms
This study is conducted by a working group of the French Society of Medical Physics (SFPM). Its main aim is to establish reference dose levels for the most common procedures performed in operating rooms using mobile X-ray…
- Trial name
- NCT03649451
- Where
- France
- Volunteers
- 8,840 people
- Sponsor
- Societe Francaise de Physique Medicale
Supraventricular Tachycardias
Radiation Exposure Reduction in Supraventricular Tachycardia Ablation
Radiofrequency catheter ablation (RFCA) is the mainstay of therapy for supraventricular tachyarrhythmias, providing cure in a high percentage of cases.
- Trial name
- NO-PARTY (NCT01132274)
- Testing
- Radiofrequency catheter ablation
- Where
- 6 sites in Italy
- Volunteers
- 210 people
- Sponsor
- Catholic University of the Sacred Heart
Altitude, Ultraviolet Rays
Ultraviolet Exposure, Antioxidant Use and Skin Erythema at Extreme High Altitude
With the increasing tourism and adventure travel into extreme environments comes the need to reassess the required protection against ultraviolet (UV) radiation and possible other oxidative stresses.
- Conditions
- Altitude, Ultraviolet Rays, Antioxidants, Oxidative Stress
- Trial name
- NCT00685438
- Where
- Nepal
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre