Clinical trials: Raman Spectroscopy
Carcinoma, Basal Cell, Intraoperative BCC Detection by Fast Raman Device
Intraoperative Detection of Residual BCC by Fast Raman
The main objective of this research is to develop a new scanning technology called the Fast Raman device, to accurately check the skin removed by the surgeon and detect any residual cancer cells; if found, additional skin can…
- Trial name
- NCT03482622
- Testing
- Fast Raman
- Volunteers
- 600 people
- Sponsor
- University of Nottingham
Raman Spectroscopy
Raman Scattering Spectroscopy to Measure Macular Pigment
This study will evaluate the ease and reliability of Raman scattering spectroscopy, a new technique to measure the amount of the pigment lutein in the retina, the light-sensitive tissue lining the back of the eye.
- Trial name
- NCT00060580
- Testing
- Raman scattering spectroscopy
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- National Eye Institute (NEI)
Cancer Diagnosis, Liver Cancer, Adult
Raman Spectroscopy-Based Deep Learning Model for Early Pan-Cancer Early Diagnosis
The goal of this observational study is to explore whether a Raman-based, deep learning-assisted approach can be used to develop an effective method for early pan-cancer screening.
- Conditions
- Cancer Diagnosis, Liver Cancer, Adult, Cancer Screening, Colorectal Cancer (CRC)
- Trial name
- NCT06822413
- Testing
- No Interventions
- Where
- 4 sites in China
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Breast Cancer Invasive
Intra-operative Detection of Positive Margins and Lymph Nodes in Breast Surgery
In this project, the investigators will develop novel optical coherence tomography (OCT)-Raman spectroscopy and autofluorescence (AF)-Raman spectroscopy systems based on a selective sampling approach optimised for high-resolution…
- Trial name
- NCT06977698
- Testing
- OCT-Raman, AF-Raman
- Where
- United Kingdom
- Volunteers
- 120 people
- Sponsor
- University of Nottingham
Crohn Disease, Pediatric Inflammatory Bowel Diseases
Microplastic Analysis in Pediatric Inflammatory Bowel Disease
The goal of this observational study is to measure and compare the presence of microplastics in children with inflammatory bowel disease (IBD) and children without IBD.
- Conditions
- Crohn Disease, Pediatric Inflammatory Bowel Diseases, Ulcerative Colitis (UC), Inflammatory Bowel Disease (IBD)
- Trial name
- MAP-IBD (NCT07141238)
- Testing
- Environmental microplastic exposure
- Where
- Poland
- Volunteers
- 40 people
- Sponsor
- Medical University of Gdansk
IgA Nephropathy (IgAN), Membranous Nephropathy
Raman Spectroscopy Diagnosis of Kidney Diseases
This research plan, from January 2021 to December 2024, aims to collect serum and morning urine from patients diagnosed with IgA nephropathy, idiopathic membranous nephropathy, diabetic nephropathy, and focal segmental…
- Conditions
- IgA Nephropathy (IgAN), Membranous Nephropathy, Diabetic Nephropathy, Focal Segmental Glomerulosclerosis (FSGS)
- Trial name
- NCT06760845
- Testing
- Imaging Time
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Zunsong Wang
Normal Vulval Skin, Lichen Sclerosus
Evaluation of the Role of Vibrational Spectroscopy in the Assessment of Vulval Disease
Can vibrational spectroscopy be used to accurately assess vulval skin conditions? Vulval skin disorders are common and the diagnosis of these conditions can be difficult.
- Conditions
- Normal Vulval Skin, Lichen Sclerosus, High Grade Dysplasia - Usual Type ('VIN 2-3'), High Grade Dysplasia - Differentiated Type ('VIN 2-3')
- Trial name
- Vulval VS (NCT02223975)
- Where
- United Kingdom
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Gloucestershire Hospitals NHS Foundation Trust
Child Nutrition, Fruit and Vegetable Intake
Pink and Dude Chef
The purpose of the study is to evaluate an afterschool program to teach nutrition through basic cooking skills. This after school extracurricular program increases the students' confidence, knowledge, and skills for cooking as…
- Conditions
- Child Nutrition, Fruit and Vegetable Intake, Healthy Food Choice, Healthy Food Preparation
- Trial name
- NCT01803997
- Testing
- Pink and Dude Chef Afterschool Cooking Program
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- USDA Grand Forks Human Nutrition Research Center
Osteoarthritis, Osteoporosis
Development of a Non-invasive Assessment of Human Bone Quality Using Spatially Offset Raman Spectroscopy
In this study spatially offset Raman spectroscopy (SORS), which allows the collection of Raman spectra through turbid media, is being applied to collect Raman spectra of bone.
- Conditions
- Osteoarthritis, Osteoporosis, Osteogenesis Imperfecta, Rickets / Osteomalacia
- Trial name
- NCT02814591
- Testing
- spatially offset Raman spectrometer (SORS)
- Volunteers
- 245 people, healthy volunteers welcome
- Sponsor
- University College, London
Diabetes Mellitus
Performance and Safety Evaluation of a Novel Non-invasive Glucose Monitoring Device and Evaluation of the Instructions for Use
The aim of the study is to demonstrate the safety and performance of a novel non-invasive glucose monitoring device, to collect data and reference measurements for establishment of calibration models and to evaluate the…
- Trial name
- NCT04033042
- Testing
- Prototype 0.5
- Where
- Germany
- Volunteers
- 10 people
- Sponsor
- RSP Systems A/S
Raman Spectroscopy, Children, Only
The Effect of a Nutrient Dense Food on the Skin CarotenoidLevels of School Age Children
Background: In a previous study, children who consumed a high-carotenoid juice over 8 weeks significantly increased skin carotenoid levels as compared to children who consumed a placebo juice.
- Trial name
- NCT03146715
- Testing
- Feeding trial
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Utah State University
Tissue Oxygenation
Tissue Oxygen Deprivation as Detected With Raman in Association With Umbilical Artery Catheters
Umbilical artery catheters (UACs) are associated with significant morbidity in preterm neonates however are necessary for the management of this high risk population.
- Trial name
- NCT04038203
- Testing
- Resonance Raman Spectroscopy (RPS)
- Where
- United States
- Sponsor
- University of Florida
Acute Lymphoblastic Leukemia
Raman Spectroscopy Compared to Flow Cytometry
The detection of MRD is associated with an increased risk of relapse and adverse prognosis in all patient groups diagnosed with acute lymphoblastic leukemia (ALL).
- Trial name
- NCT06291428
- Testing
- Raman spectroscopy
- Where
- Mexico
- Volunteers
- 50 people
- Sponsor
- Hospital Regional de Alta Especialidad del Bajio
Reproductive Issues, Subfertility
A Novel Integrative Non-invasive Embryo Selection Approach for IVF Based on MK-RS Analysis
During assisted reproductive technology treatment, embryo selection is an important process that may affect the clinical pregnancy rate.
- Conditions
- Reproductive Issues, Subfertility, IVF
- Trial name
- NCT05896709
- Testing
- MK-RS
- Where
- Hong Kong
- Volunteers
- 176 people
- Sponsor
- Chinese University of Hong Kong