Clinical trials: Randomised Controlled Trial
Acute Respiratory Infection, Asthma Exacerbations
Reusable Face Masks to Reduce Risk of Viral Respiratory Infections and Asthma Exacerbations
REMASK trial is a Trial within Cohort study (TwiCs), nested within the COVIDENCE UK longitudinal study. It has been designed to determine whether the offer of a free reusable, elastomeric face mask to adults with asthma and other…
- Trial name
- REMASK (NCT06885229)
- Testing
- FloMask - reuseable face mask
- Where
- United Kingdom
- Volunteers
- healthy volunteers welcome
- Sponsor
- Queen Mary University of London
Influenza
ADITEC FLU STUDY: Understanding the Genetic Basis for Immune Responses
Infants and young children do not respond as well as adults to the flu vaccines currently available in the UK. Fluad, is a different type of influenza vaccine that has been available in the European continent for the last decade…
- Trial name
- NCT01682369
- Testing
- TIV (Aggripal), ATIV (Fluad)
- Where
- United Kingdom
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Tobacco Prevention
Effectiveness of an Online Quiz in Promoting Tobacco-Related Knowledge, Attitudes, and Behaviours Among Primary Students
The goal of this modified pilot RCT is to evaluate the effects of the intervention (online platform) on tobacco-related knowledge, attitudes and intentions on smoking among local primary 5-6 school students.
- Trial name
- NCT06913166
- Testing
- Online quiz competition
- Where
- Hong Kong
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Dietary Deficiency
Fish Consumption and Dietary Diversity in Timor-Leste
A one-year, cluster-randomized, partially masked, controlled trial to test and compare the effects of fish aggregating devices and social and behaviour change communication on the frequency and volume of household fish…
- Trial name
- NCT04729829
- Testing
- Social and behaviour change communication, Fish aggregating device
- Where
- Timor-Leste
- Volunteers
- 720 people, healthy volunteers welcome
- Sponsor
- WorldFish
Child Malnutrition
Effects of Prebiotics on Metagenomic Diversity and Abundance in Young Children With Acute Malnutrition
Malnutrition is a major global public health issue, contributing to poor health and early morbidities in children under five, particularly in developing countries.
- Trial name
- P-MAM (NCT06155474)
- Testing
- Prebiotic galacto-oligosaccharide (GOS) Powder, Starch Only, RUTF + Starch
- Where
- Pakistan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of the Punjab
Iron Deficiency, Anaemia in Children
A Novel Nano-iron Supplement to Safely Combat Iron Deficiency and Anaemia in Young Children: a Doubleblind Randomised Controlled Trial
This study aims to determine whether IHAT is non-inferior to ferrous sulphate at correcting iron deficiency and anaemia, and if IHAT does not increase diarrhoea risk in young children living in rural and resource-poor areas of…
- Trial name
- IHAT-Gut (NCT02941081)
- Testing
- IHAT, Ferrous Sulphate
- Where
- The Gambia
- Volunteers
- 645 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Zirconia Crowns
Custom-made Zirconia Crowns Versus Prefabricated Zirconia Crowns in Young Permanent Molars
This study aims to compare the clinical performance of Prefabricated Zirconia Crowns (PZCs) with that of Custom-made Zirconia Crowns (CZCs) using enhanced clinical protocols.
- Trial name
- NCT07704151
- Testing
- Prefabricated Zirconia Crown, Custom-made Zirconia Crowns
- Where
- Jordan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
Tramadol for Labor Analgesia
Tramadol for Labor Analgesia: a Placebo Controlled Randomised Control Trial
Tramadol for labor analgesia: a low risk placebo controlled randomised control trial
- Trial name
- NCT02999594
- Testing
- Tramadol Hydrochloride, Distilled Water
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Maulana Azad Medical College
Acquired Brain Injury Including Stroke, Epilepsy
Cognitive Rehabilitation Using Neurofeedback With Brain-computer Interface
The goal of this clinical trial is to determine whether a Brain-Computer Interface Neurofeedback Training (BCI-NFT) programme can improve cognitive outcomes, and whether electroencephalography (EEG)-based measures can serve as…
- Trial name
- NCT07828496
- Testing
- Brain-computer interface with neurofeedback with 3D game sessions
- Where
- Singapore
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- KK Women's and Children's Hospital
Asthma
Self-management Intervention to Improve Adolescents' Asthma Control
Approximately 1.1 million children and young people in the United Kingdom (UK) are living with asthma, making it the most common chronic disease in children in the UK.
- Trial name
- MAIS (NCT03536416)
- Testing
- My Asthma in School
- Where
- United Kingdom
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Queen Mary University of London
Dental Caries
European Study on Three Different Approaches to Managing Class 2 Cavities in Primary Teeth
The purpose of this randomized clinical trial is to compare the clinical effectiveness of three treatments involving different caries management strategies (conventional restorations, Hall technique, and Non-Restorative Caries…
- Trial name
- NCT01797458
- Testing
- Hall Technique, Non-Restorative Caries Treatment, Conventional Restoration
- Where
- 3 sites in Germany, Lithuania and 1 more
- Volunteers
- 169 people, healthy volunteers welcome
- Sponsor
- University Medicine Greifswald
Scoliosis
A Postural Study Comparing Sitting on the Floor Versus Sitting in a Chair While Playing Video Games.
To determine if sitting in a chair or sitting on the floor lends itself to better posture while playing video games.
- Trial name
- NCT01163955
- Testing
- Time to fatigue
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Glinn and Giordano Physical Therapy
Preterm Birth, Pregnancy Trimester, Second
Progesterone for Prevention of Preterm Birth in Women With Short Cervix: Randomized Controlled Trial
The aim of our study is to evaluate the effect of use of prophylactic vaginal progesterone on the incidence of severe preterm delivery, defined as delivery before 33+6 weeks in women with a short cervical length of 15mm.
- Trial name
- NCT00422526
- Testing
- Micronised progesterone (Utrogestan)
- Where
- 8 sites in Brazil, Chile and 2 more
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- King's College Hospital NHS Trust
Peer Review, Publishing, Completeness of Reporting
Evaluating the Impact of Assessing During Peer Review the CONSORT Checklist Submitted by Authors
Randomised trials are considered the gold standard in medical research. The CONSORT (Consolidated Standards of Reporting Trials) Statement aims to improve the quality of reporting of randomised trials.
- Trial name
- NCT03751878
- Testing
- Evaluation of reporting inconsistencies, Standard Peer Review.
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Universitat Politècnica de Catalunya
Regurgitation, Gastric
Evaluation of the Tolerance and Safety of a New Partly Fermented Anti-regurgitation Infant Formula
A randomised, controlled, double-blind trial to evaluate the tolerance and safety of a new partly fermented anti-regurgitation infant formula containing prebiotics and locust bean gum in infants with regurgitation.
- Trial name
- Leopard (NCT03371615)
- Testing
- Anti-regurgitation infant formula
- Where
- 2 sites in Poland
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- Nutricia Research
Malaria
The Combined Use of Indoor Residual Spraying (IRS) and Long-lasting Insecticidal Nets (LLINs) for Malaria Prevention
The study is a cluster randomised trial to compare the effectiveness of indoor residual spraying (IRS) combined with the use of long lasting insecticidal nets (LLINs) with the effectiveness of LLINs alone for preventing malaria…
- Trial name
- NCT01697852
- Testing
- Indoor residual spraying with bendiocarb, LLIN by universal coverage campaign
- Where
- Tanzania
- Volunteers
- 22,300 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Adult
Communicating Evidence From Systematic Reviews to the Public
The purpose of this randomised controlled trial is to compare a new standardised summary format for presentation of synthesised evidence from systematic reviews for the public (a new plain language summary format) to the current…
- Trial name
- PLSRCT (NCT01939925)
- Testing
- New plain language summary format, Current plain language summary format
- Where
- 5 sites in Argentina, Canada and 3 more
- Volunteers
- 193 people, healthy volunteers welcome
- Sponsor
- Norwegian Knowledge Centre for the Health Services
Language Development
Reading Together: How to Promote Children's Language Development Using Family-based Shared Book Reading
The aim of this project is to determine how shared reading promotes child language development, and to use this knowledge to make it an effective language-boosting tool for children from all social and economic backgrounds.
- Trial name
- NCT02625584
- Testing
- Reading Together - Pausing for Reading, Reading Together - Dialogic Reading, Reading Together - Shared Reading Control
- Where
- United Kingdom
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Caroline Rowland
Dengue, Vector Borne Diseases
Sustainable Reduction of Dengue in Colombia: Vector Breeding Site Intervention With an Insecticidal Coating
Effective control of Aedes aegypti mosquitoes in breeding sites with high reproductive rates could have a major impact on reducing arbovirosis in endemic communities.
- Conditions
- Dengue, Vector Borne Diseases, Arbovirus Infections, Zika
- Trial name
- NCT06268691
- Testing
- Insecticide Coating INESFLY
- Where
- 2 sites in Colombia, Germany
- Volunteers
- 35,000 people, healthy volunteers welcome
- Sponsor
- Rocio Cardenas Sanchez
Eating Behaviour of Discretionary Foods
Understanding the Impact of Physical Activity Calorie Equivalent (PACE) Labelling in Secondary Schools
The aim is to undertake a cluster randomised controlled trial to assess the effectiveness of PACE food labelling in reducing young people's purchasing of discretionary foods in secondary school canteens.
- Trial name
- NCT05623618
- Testing
- PACE labelling
- Where
- United Kingdom
- Volunteers
- 8,000 people, healthy volunteers welcome
- Sponsor
- Loughborough University