Clinical trials: Randomized Controlled Trial (RCT)
Anxiety, Anxiety Disorders
The Impact of a School-Based, Trauma-Informed CBT Intervention for Young Women
The purpose of this study is: 1. To conduct a randomized controlled trial to evaluate the impact of Working on Womanhood (WOW), a school-based, trauma-informed counseling and clinical mentoring program for young women in Chicago…
- Conditions
- Anxiety, Anxiety Disorders, Behavioral Symptoms, Depression
- Trial name
- NCT03376633
- Testing
- Working on Womanhood (WOW)
- Where
- United States
- Volunteers
- 5,106 people
- Sponsor
- University of Chicago
VLBW - Very Low Birth Weight Infant
Feeding Study in VLBW Premature Infants
A multi-center, single-blind, randomized, controlled, parallel-designed, prospective trial to compare growth between preterm infants fed one of three study human milk fortifiers added to human milk
- Trial name
- NCT05744193
- Testing
- Exempt Infant Formula
- Where
- 6 sites in United States
- Volunteers
- 22 people
- Sponsor
- Mead Johnson Nutrition
Obesity, Hypertension
Postpartum Weight Retention
The Postpartum Weight Management Study is a true community-academic collaboration, bringing together Maternity Care Coalition (MCC) staff and the investigator, Dr.
- Conditions
- Obesity, Hypertension, Depression
- Trial name
- NCT02867631
- Testing
- 6 week challenge with 1 year of home visits: health texting, in home exercise supports, social support, healthy eating and feeding classes
- Where
- United States
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Cancer
Effectiveness of Ultrasound-Guided Versus Traditional IV Insertion by Oncology Nurses in Adult Population Recieving Systemic Anti-cancer Therapy
What is this study about? This study is comparing two different methods nurses use to place an intravenous (IV) drip, which is needed for many cancer treatments. Traditional method: The nurse finds a vein by touch and sight.
- Trial name
- EUPIC (NCT07208175)
- Testing
- Ultrasound-Guided Peripheral Intravenous Catheter Insertion, Traditional Peripheral Intravenous Catheter Insertion
- Where
- 2 sites in Ireland
- Volunteers
- 98 people
- Sponsor
- University of Galway
Dental Anxiety
Evaluation of Pain Perception and Heart Rate in Children Who Received Dental Anesthesia
The aim of this single-blind split-mouth study is to compare traditional syringe technique versus computer-controlled Wand® anesthetic System to evaluate pain perception, assessed with Visual Numerical Rating Scale, and heart…
- Trial name
- RCT (NCT03348800)
- Testing
- Dental anesthesia
- Where
- Italy
- Volunteers
- 76 people
- Sponsor
- Catholic University of the Sacred Heart
Pediatric Readiness
Pediatric Readiness Intervention in Manitoba
The goal of this clinical trial is to improve emergency care of children in Manitoba by increasing the weighted pediatric readiness scores (WPRS) of the general EDs through the implementation of provincially derived…
- Trial name
- NCT06257524
- Testing
- Education and training
- Where
- Canada
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Heat Cramps, Heat Rash
Testing Interventions to Mitigate the Health Impact of Heatwaves on Primary School Children in Climate-vulnerable Districts of Bangladesh.
The goal of this clinical trial is to assess the impact of implementing a combination of heat education and school-based physical infrastructure interventions in reducing heat related illnesses and improving educational outcomes…
- Conditions
- Heat Cramps, Heat Rash, Heat Exhaustion, Heat Stress
- Trial name
- NCT07877935
- Testing
- Solar reflective paint, Bamboo ceiling with polyethylene foam, Heat education toolkit
- Where
- 2 sites in Bangladesh
- Volunteers
- 2,875 people, healthy volunteers welcome
- Sponsor
- BRAC University
Psychotic Episode, Psychological Trauma
A Rater-blinded RCT to Compare Effectiveness of EMDR vs TAU in Patients With First Episode Psychosis and History of Psychological Trauma
The main objective of this project is to analyze whether EMDR therapy, as an adjuvant to usual treatment, is effective in reducing post-traumatic stress and psychotic/affective symptoms in patients with a FEP and comorbid…
- Trial name
- NCT03991377
- Testing
- Eye movement desensitization and reprocessing therapy, Treatment as usual
- Where
- Spain
- Volunteers
- 71 people
- Sponsor
- Parc de Salut Mar
Gastrointestinal Tolerance, Gastrointestinal Symptoms
Gastrointestinal Symptoms and Tolerance in Infants Fed Goat or Cow's Milk-based Infant Formula
This randomized controlled double-blind study will compare the effect of a commercially available goat milk formula to a cow's milk formula on gastrointestinal symptoms and tolerance, and infections in infants.
- Conditions
- Gastrointestinal Tolerance, Gastrointestinal Symptoms, Infections, Quality of Life
- Trial name
- MESK-2 (NCT07342972)
- Testing
- Goat milk-based infant formula, Cow's milk-based infant formula
- Where
- Saudi Arabia
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Ausnutria Hyproca B.V.
Balance; Distorted, Fall
Improving Balance Through Balance Exercise
Today most fracture prevention measures targets the bone and osteoporosis. However, only about 20% of individuals with fractures have osteoporosis and at least 90% of all fractures are caused by a fall.
- Trial name
- NCT03227666
- Testing
- Exercise
- Where
- Sweden
- Volunteers
- 52 people
- Sponsor
- Region Västerbotten
Flaccid Paresis, Spastic Paresis
Comparing Digitally and Traditionally Made Ankle Foot Orthoses
The research is being done to compare two methods of creating AFOs: 1. The traditional method, which involves manually creating a mold from a plaster cast of the client's limb. This is time-consuming and labor-intensive; and 2.
- Conditions
- Flaccid Paresis, Spastic Paresis, Cerebral Palsy, Stroke
- Trial name
- NCT06828653
- Testing
- Part A First Wear Period: Traditional AFO(s), Part A First Wear Period: Digital AFO(s), Part A Second Wear Period: Traditional AFO(s)
- Where
- 2 sites in Canada
- Volunteers
- 50 people
- Sponsor
- Holland Bloorview Kids Rehabilitation Hospital
Prostate Cancer
ADT Exercise Trial and Economic Analysis
Prostate Cancer (PC) affects 1 in 7 men. Nearly half of those diagnosed with PC will receive androgen deprivation therapy (ADT) as part of their treatment. ADT is good at managing PC but has many side effects.
- Trial name
- ADTExRCT (NCT02834416)
- Testing
- Supervised Group Exercise, Home Based Exercise
- Where
- 4 sites in Canada
- Volunteers
- 38 people
- Sponsor
- University Health Network, Toronto
Anxiety Disorders
Stepped vs Stratified Care for Pediatric Anxiety Disorders
The purpose of this trial is to evaluate the feasibility, acceptability, and safety of two care pathways (including internet-delivered cognitive behavioral therapy [CBT] and/or in-person CBT) for children and adolescents with…
- Trial name
- PMAX (NCT06016907)
- Testing
- Internet-delivered cognitive behavioral therapy (ICBT), In-person cognitive behavioral therapy (CBT)
- Where
- Sweden
- Volunteers
- 51 people
- Sponsor
- Region Skane
Bladder and Bowel Disorder, Pediatric
Diaphragmatic Breathing as an Adjunctive Therapy in the Management of Children With Bladder and Bowel Disorders
Urination is a result of a complex neuro-muscular coordination which involves the action and arrangement of different parts of nervous systems as well as the muscular structure of the lower part of the urinary system.
- Trial name
- NCT02597764
- Testing
- Diaphragmatic Breathing, Standard Urotherapy
- Where
- Canada
- Volunteers
- 23 people
- Sponsor
- University of British Columbia
Dental Caries in Children
Evaluation of New Different Herbal Mouthwashes Against Caries Forming Bacteria, RCT
The goal of this randomized controlled trial is to compare three different types of mouthwash, Moringa, Star anis, and Indian Costus 90 children participated in this study divided into 3 groups according to the type of mouthwash…
- Trial name
- NCT05623605
- Testing
- Moringa mouthwash, star anise mouthwash, Indian costus mouth wash
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Nahda University
Appropriateness of Prescribing in Older Patients
RCT Assessing the Impact of Online Training on Doctors' Prescribing for Older Patients
This study will assess, by means of a randomized controlled trial, the impact of an online educational tool, on doctors' knowledge and confidence with regards to prescribing for older patients.
- Trial name
- NCT02405975
- Testing
- SCRIPT
- Where
- Ireland
- Volunteers
- 100 people
- Sponsor
- University College Cork
Premenstrual Syndrome
Follow-up Assessment of a Trial of Open-label Placebos for Women With Premenstrual Syndrome
With the proposed study, the investigators aim to evaluate the long-term efficacy of the open-label placebo (OLP) intervention in premenstrual syndrome (PMS) and to contribute to a broader understanding of how OLPs work.
- Trial name
- NCT06206460
- Testing
- Online Assessment
- Where
- Switzerland
- Volunteers
- 66 people
- Sponsor
- University Hospital, Basel, Switzerland
HIV Infections
RCT of Russian IDU Peer Network HIV Prevention Intervention - 1
The purpose of this study is to conduct a randomized controlled trial to assess the efficacy of a peer-educator intervention focused on injection drug users and their drug and sexual networks.
- Trial name
- NCT00218673
- Testing
- Peer mentor intervention
- Where
- Russia
- Volunteers
- 400 people
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Infertility, Female, Reproductive Techniques, Assisted
SISTER: Sibling Oocyte Insemination With Frozen Sperm From Third Party Donors: Evaluation of Reproductive Techniques
The goal of this clinical trial is to learn whether two different methods of helping eggs and sperm join-intracytoplasmic sperm injection (ICSI) and conventional in vitro fertilization (IVF)-lead to better embryo development when…
- Conditions
- Infertility, Female, Reproductive Techniques, Assisted, Fertilization in Vitro
- Trial name
- SISTER (NCT07175571)
- Testing
- Intracytoplasmic Sperm Injection (ICSI), Conventional Insemination (IVF)
- Where
- United States
- Volunteers
- 95 people
- Sponsor
- Shady Grove Fertility Reproductive Science Center
Language Development Disorders
Improving STEM Outcomes for Young Children With Language Learning Disabilities Via Telehealth
In this study the investigators focus on a subset of at-risk students who find the language of science to be a barrier to the learning of science. These are the nearly 3 million children in the U.S.
- Trial name
- NCT04775199
- Testing
- Language Intervention
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Karla McGregor