Clinical trials: Randomized-controlled Trial
Chlamydia
Home-sampling in Partner Notification of Chlamydia
Though partner notification is mandatory to perform of Chlamydia trachomatis infected individuals in Sweden, there was a 10-15% annually increase of reported cases between 1997 and 2007 indicating that partner notification may…
- Trial name
- NCT01596946
- Testing
- Contact tracing mode test at clinic, Self-sampling at home - Sent Test Kit
- Where
- Sweden
- Volunteers
- 633 people, healthy volunteers welcome
- Sponsor
- Ostergotland County Council, Sweden
Type 1 Diabetes, Type 1 Diabetes Mellitus
Alleviating Carbohydrate Counting for Patients With Type 1 Diabetes Using a Novel Insulin-plus-pramlintide Artificial Pancreas
One of the main challenges in maintaining tight glucose control in a closed-loop system occurs at meal times. Amylin is a gluco-regulatory beta-cell hormone that is co-secreted with insulin in response to nutrient stimuli, and is…
- Conditions
- Type 1 Diabetes, Type 1 Diabetes Mellitus, Hyperglycemia, Postprandial
- Trial name
- NCT04163874
- Testing
- Fiasp, Pramlintide Acetate, Artificial Pancreas
- Where
- Canada
- Volunteers
- 36 people
- Sponsor
- McGill University
White Spot Lesion of Tooth, Orthodontic Treatment
S-PRG Filler for Preventing White Spot Lesions During Orthodontic Treatment
White spot lesions are early areas of enamel demineralization that may develop during orthodontic treatment with fixed braces. This study aims to evaluate the effectiveness of S-PRG Barrier Coat in preventing white spot lesions…
- Conditions
- White Spot Lesion of Tooth, Orthodontic Treatment, Enamel Demineralization, Fluoride Varnishes
- Trial name
- SPRG-WSL (NCT07839780)
- Testing
- S-PRG Barrier Coat, S-PRG Barrier Coat + 5% Sodium Fluoride Varnish, 5% sodium fluoride varnish
- Where
- Malaysia
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- National University of Malaysia
Adherence, Medication, HIV/AIDS
Short Adherence Intervention for Viral Re-suppression
In the era of test-and-treat, with anticipated high numbers of patients who will have unsuppressed viral load (VL) due to poor adherence, simple, short and standardized adherence interventions with documented efficacy will be…
- Trial name
- SAVIR (NCT03242980)
- Testing
- Structured adherence counseling
- Where
- 12 sites in Lesotho
- Volunteers
- 928 people
- Sponsor
- Swiss Tropical & Public Health Institute
Pneumonia, Vitamin D Deficiency
Kabul Vitamin D Supplementation Trial
Background: Pneumonia is the leading cause of childhood mortality, accounting for 19% of the 10.6 million deaths that occur each year1.
- Trial name
- NCT00548379
- Testing
- vitamin D
- Where
- 2 sites in Afghanistan
- Volunteers
- 3,048 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Struck by Soccer Ball
Is Kinesio Taping Better Than Placebo Taping for Improving Performance During Unilateral Vertical Jump and Hop Tests?
Introduction: Kinesio taping consists of the attachment of a thin elastic tape over specific muscles, the thickness of which is similar to that of the epidermis.
- Trial name
- NCT02560961
- Testing
- Kinesio Taping (Kinesio Tex Gold®; color: black)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Acute Respiratory Failure, Acute Hypoxemic Respiratory Failure
Comparing Closed-loop FiO2 Controller With Conventional Control of FiO2
During mechanical ventilation (MV) hypoxemic or hyperoxemic events should be carefully monitored and a quick response should be provided by the caregiver at the bedside.
- Conditions
- Acute Respiratory Failure, Acute Hypoxemic Respiratory Failure, Acute Hypoxemic and Hypercapnic Respiratory Failure
- Trial name
- NCT04568642
- Testing
- Activate FiO2 controller, Deactivate FiO2 controller
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Dr. Behcet Uz Children's Hospital
Orogastric Tube Insertion
Pain Perception Associated With Orogastric Tube Insertion in Preterm Infants
This study is a randomized controlled experimental study designed to examine the effect of white noise and swaddling methods in reducing the pain caused by orogastric tube insertion in preterm infants.
- Trial name
- NCT04678570
- Testing
- White Noise, Swaddling Method
- Where
- Turkey (Türkiye)
- Volunteers
- 132 people
- Sponsor
- Afyonkarahisar Health Sciences University
Community-acquired Pneumonia
The Effect of Huashibaidu Granule on Community-acquired Pneumonia in Children
The primary purpose of this study is to assess the efficacy and safety of Huashibaidu granule for the treatment of community-acquired pneumonia in children compared with placebo and to demonstrate the efficacy of Huashibaidu…
- Trial name
- NCT05711017
- Testing
- Huashibaidu granule
- Volunteers
- 100 people
- Sponsor
- Shanghai Children's Medical Center
Nursing Education, Nursing Process
GENERATİVE AI-SUPPORTED NURSİNG PROCESS EDUCATİON AND NURSİNG STUDENTS' LEARNİNG OUTCOMES
This randomized controlled trial evaluated the effect of generative artificial intelligence (AI)-supported education in teaching the nursing process on nursing students' learning outcomes.
- Conditions
- Nursing Education, Nursing Process, Learning Outcome, Generative Artificial Intelligence
- Trial name
- NCT07905040
- Testing
- Generative AI-Supported Nursing Process Education, Case Study-Based Nursing Process Education
- Where
- Turkey (Türkiye)
- Volunteers
- 173 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Molar Hypomineralization
Intraosseus Injection Using Extra-short Needle Combined With Infiltration in Pediatric Patients With Molar Incisor Hypomineralization
Background: Effective pain control is crucial in managing pediatric dental patients. Molar-incisor hypomineralization (MIH), marked by enamel defects and dentin hypersensitivity, often hinders effective local anesthesia.
- Trial name
- NCT07239050
- Testing
- intraosseus anesthesia, Conventional nerve block
- Where
- Egypt
- Volunteers
- 26 people
- Sponsor
- Alexandria University
Pediatric Cancer
Narrative-based Card Game in Improving Spiritual Well-being Among Chinese Childhood Cancer Patients
Cancer as a life-threatening disease can trigger children's unique spiritual needs. Unmet spiritual needs can cause low level of spiritual well-being, which is a central component for the overall quality of life (QoL) of cancer…
- Trial name
- NCT05639062
- Testing
- Narrative-based card game
- Where
- Hong Kong
- Volunteers
- 60 people
- Sponsor
- The Hong Kong Polytechnic University
Meningitis in Children
The Use of an Audio-visual Method in Counseling for Pediatric Lumbar Puncture Procedure
The goal of this clinical trial is to compare the use of usual verbal counseling supported by a video illustration comparing to the use of usual verbal counseling alone prior to obtaining spinal fluid ( Lumbar puncture - LP )…
- Trial name
- NCT07409220
- Testing
- Audio-visual tool/ Video
- Where
- Oman
- Volunteers
- 154 people
- Sponsor
- Oman Ministry of Health
Pancreatic Cancer
Research of the Application of Artificial Intelligence Model "PANDA"
The research objective of this project is to conduct a large-scale and prospective real-world validation of the Pancreatic Cancer Screening Model PANDA, which was developed based on deep learning and plain CT scans in previous…
- Trial name
- NCT06528223
- Testing
- biopsy or operation
- Where
- 2 sites in China
- Volunteers
- 200,000 people, healthy volunteers welcome
- Sponsor
- Zhejiang University
Diabetes Mellitus
Effectiveness of Phone Calls Intervention on Diabetic Patients After Ambulatory Discharge of a Tertiary Care Center
The study is a randomized clinical trial, controlled, open label that aimed to compare two groups after discharge of a tertiary care: type 2 diabetes patients followed exclusively by primary care (control group) and patients…
- Trial name
- NCT02768480
- Testing
- Primary Care, Phone Calls Support and Primary Care
- Where
- Brazil
- Volunteers
- 147 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Vitrectomy
Clinical Trial of Intravitreal Microplasmin in Infants and Children Scheduled for Vitrectomy
To evaluate the safety and preliminary efficacy of intravitreal microplasmin as an adjunct to conventional vitrectomy for the treatment of pediatric patients.
- Trial name
- MIC (NCT00986362)
- Testing
- Ocriplasmin
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- ThromboGenics
HIV/AIDS, Hypertension
Evaluating the Impact of a Community Health Worker Program in Neno, Malawi
This protocol concerns the implementation and evaluation of an intervention designed to realign the existing cadre of Community Health Workers (CHW) in Neno District, Malawi to better support the care needs of the clients they…
- Conditions
- HIV/AIDS, Hypertension, Asthma, Diabetes
- Trial name
- NCT03106727
- Testing
- Household model
- Where
- Malawi
- Volunteers
- 122,395 people, healthy volunteers welcome
- Sponsor
- Partners in Health
Autism Spectrum Disorder
A Placebo-controlled Trial of Folinic Acid in Children With ASD
Autism spectrum disorder (ASD) is a neurodevelopmental condition characterized by difficulties in social communication and the presence of restricted or repetitive behaviors.
- Trial name
- AFAT (NCT07642661)
- Testing
- Folinic Acid
- Where
- Israel
- Volunteers
- 150 people
- Sponsor
- Prof. Adi Aran
Anxiety and Depression
Guided Narrative Technique After Coronavirus Outbreak Influencing Positive and Negative Emotions and Cognition for Children--A Randomized Controlled Trial
At the beginning of 2020, the COVID-19 broke out in Wuhan, raging across the country quickly afterwards. As a sudden public health emergency, this epidemic caused some stress reactions (including emotional, cognitive, and…
- Trial name
- NCT06708442
- Testing
- School-based CBT intervention, Guided Narrative Technique (GNT) Writing, Guided Narrative Technique (GNT) drawing
- Where
- China
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Peking University
Pediatric Cataract, IOL Implantation
Myopia Progression Control Using Atropine 0.05% After Pediatric Cataract Surgery And Intraocular Lens Implantation Surgery
Myopic shift remains a debilitating and unpredictable adverse event following pediatric cataract surgery. While research exploring peripheral myopic defocus for post-cataract surgery myopia prevention shows promising results, the…
- Conditions
- Pediatric Cataract, IOL Implantation, Myopia Progression
- Trial name
- NCT07364370
- Testing
- Atropine Eye drops
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
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