Clinical trials: Randomized-controlled Trial
Diabetes Mellitus, Type 1
Assess the Impact of Insulclock on Glycemic Variability and Treatment Compliance in Uncontrolled DM1 Patients
Insulclock® is a small electronic device developed to facilitate the optimal administration of insulin. This device works as an add-on module of commercially available insulin pens and monitors the date, time and dose of…
- Trial name
- Segoclock2 (NCT04847778)
- Testing
- Use of Insulclock system, both Insulclock device and Insulclock 360 app., Use of Insulclock system, both Insulclock device and Insulclock app on masked mode.
- Where
- 4 sites in Spain
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Hospital General de Segovia
Psychosocial Intervention
Managing Challenging Behaviors-ADHD
The purpose of this study is to test whether short, time-limited parent education programs designed to help children diagnosed with ADHD and disruptive behaviors can be helpful to families that may not be able to participate in…
- Trial name
- MCB-ADHD (NCT05674968)
- Testing
- Managing Challenging Behaviors in ADHD; Psychosocial program
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
Infertility
Follicular Flushing in Patients With Suboptimal Responses
The aim of the present study is to determine the effect of follicular flushing on the ongoing pregnancy rate in patients who developed four or fewer follicles of 14mm following standard ovarian stimulation for IVF.
- Trial name
- NCT02277210
- Testing
- Flushing
- Where
- China
- Volunteers
- 4 people
- Sponsor
- The University of Hong Kong
Vaginitis
Saginil in vs. Placebo for Gynecologic Oncology Patients Affected by Vaginitis
We hypothesise that the use of Adelmidrol (Saginil in vaginal cannulas) can reduce the incidence and magnitude of vaginitis in patients affected by gynecologic malignancies.
- Trial name
- NCT01420510
- Testing
- Adelmidrol vaginal gel
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Università degli Studi dell'Insubria
COVID-19
Trial to Evaluate Efficacy and Safety of Nitazoxanide in the Treatment of Mild or Moderate COVID-19
Trial to Evaluate Efficacy and Safety of Nitazoxanide in the Treatment of Mild or Moderate COVID-19
- Trial name
- NCT04486313
- Testing
- Nitazoxanide, Vitamin Super B-Complex
- Where
- 2 sites in United States
- Volunteers
- 935 people
- Sponsor
- Romark Laboratories L.C.
Headaches
RCT Evaluating Intranasal Fentanyl in the Pain Management of Children With Headaches
Background : Headaches are a common presentation for children consulting to the Emergency Department (ED). However, only few studies have evaluated the rapid pain improvement provided by medications in the acute management of…
- Trial name
- NCT02638506
- Testing
- Fentanyl, Salinex
- Where
- Canada
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- St. Justine's Hospital
ADHD - Combined Type
A School-Based Intervention to Improve Social Functioning
Evaluating interventions for children/adolescents with Attention Deficit Hyperactivity Disorder (ADHD) is a field that offers many challenges.
- Trial name
- NCT03313349
- Testing
- Psychotherapy: 1. cognitive therapy 2.family intervention
- Where
- Denmark
- Volunteers
- 32 people
- Sponsor
- Behandlingsskolerne
Mouth, Edentulous, Complete Edentulism
Cost-effectiveness of the Single-implant Mandibular Overdenture Versus Mandibular Conventional Denture
This is a randomized clinical trial designed to assess the 1-year effectiveness of two treatment modalities for the mandibular edentulists: conventional complete dentures and single-implant mandibular overdenture.
- Trial name
- NCT03463174
- Testing
- Mandibular overdenture, Mandibular complete denture
- Where
- Brazil
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Goias
Infertility
Evaluation of a Mobile Preconception Lifestyle Programme in Couples Undergoing In Vitro Fertilisation
The aim of the PreLiFe RCT is to assess the effects of a new mobile preconception lifestyle programme (PreLiFE-programme) for couples undergoing IVF.
- Trial name
- PreLiFe-RCT (NCT03790449)
- Testing
- PreLiFe-programme, Attention Control Programme
- Where
- 5 sites in Belgium
- Volunteers
- 211 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Healthy Infants
Starter Infant Formula With Synbiotics
This randomized, double-blind, controlled intervention trial aims to evaluate the safety and efficacy of a starter infant formula supplemented with an HMO blend and a probiotic, and will provide evidence on the safety and…
- Trial name
- NCT06073652
- Testing
- Control 1st age starter infant formula, Experimental 1st age starter infant formula
- Where
- 3 sites in Philippines
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Abortion in First Trimester, Abortion Early
A Patient Decision Aid for Method of Early Abortion: a Randomized Control Trial
Introduction: There are two options for women seeking early pregnancy termination in Canada; either surgical or medication abortion.
- Conditions
- Abortion in First Trimester, Abortion Early, Decision Aid, Clinical Decision-making
- Trial name
- NCT05182008
- Testing
- Decision aid, Usual care
- Where
- Canada
- Volunteers
- 365 people, healthy volunteers welcome
- Sponsor
- Nova Scotia Health Authority
Necrotic Pulp
Efficacy of Guedes-Pinto Paste and CTZ Paste in the Non-instrumental Endodontic Treatment of Primary Teeth
The maintenance of the deciduous tooth until its physiological exfoliation occurs is one of the main objectives of pediatric dentistry.
- Trial name
- NCT04587089
- Testing
- Irrigation, Filling with Guedes-Pinto Paste, Filling with CTZ Paste
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Healthy
Effects of InFat™ Product on Stool Biochemistry and Stool Characteristics in Formula-fed Term Chinese Infants
The purpose of this study is to demonstrate the efficacy of infant formula having proportion of palmitate in the sn-2 position comparable to human milk in Chinese term infants.
- Trial name
- NCT00480948
- Testing
- Infant formula feeding (InFat™), Control
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Enzymotec
Meningococcal Meningitis
A Clinical Trial of ACYW135 Group Meningococcal Polysaccharide Conjugate Vaccine (CRM197 Vector) in 7 to 17 Year Olds
This is a randomized, blinded, peer-controlled study. There will be 2 treatment groups, screened subjects were given study numbers in the order of enrollment and randomly assigned to the test and control groups in a 1:1 ratio.
- Trial name
- NCT06700148
- Testing
- MCV4, MPSV4
- Where
- 2 sites in China
- Volunteers
- 840 people, healthy volunteers welcome
- Sponsor
- CanSino Biologics Inc.
Hereditary Angioedema
A Phase III, Crossover Trial Evaluating the Efficacy and Safety of KVD900 (Sebetralstat) for On-Demand Treatment of Angioedema Attacks in Adolescent and Adult Patients With Hereditary Angioedema (HAE)
This study is a randomized, double-blind, placebo-controlled, phase III, three-way crossover clinical trial evaluating the efficacy and safety of KVD900, in the treatment of hereditary angioedema attacks in adolescent and adult…
- Trial name
- NCT05259917
- Testing
- KVD900 600 mg, KVD900 300 mg
- Where
- 66 sites in United States, Australia and 19 more
- Volunteers
- 136 people
- Sponsor
- KalVista Pharmaceuticals, Ltd.
Influenza Human
Face Masks for Preventing Influenza Transmission
This work aims to measure the effectiveness of face mask worn by a patient with flu to avoid transmission to other persons in the household.
- Trial name
- GRIPMASK (NCT00774774)
- Testing
- control, Face mask
- Where
- France
- Volunteers
- 372 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Pediatric Hematology, Pediatric Oncology
Effect of Hand Puppet and Squeeze Toys on IV Placement in Pediatric Oncology Patients
This randomized controlled trial investigates hand puppet and squeeze toy techniques to reduce fear, emotional distress, and procedure time, and improve IV catheter placement success in 90 pediatric hematology-oncology patients…
- Trial name
- NCT07493018
- Testing
- Performing a Hand Puppet to Music, Hand Squeezing Soft Toy (Squishy)
- Volunteers
- 90 people
- Sponsor
- Akdeniz University
Asthma, Adolescent Behavior
The Effectiveness of Peer-education Programs for Adolescents Diagnosed With Asthma
The research was planned in a randomized controlled trial to evaluate the effect of technology-based education provided by peers and adults to children diagnosed with asthma in the 14-17 age group.
- Conditions
- Asthma, Adolescent Behavior, Self Efficacy, Peer Support and Chronic Disease
- Trial name
- NCT06392490
- Testing
- Technology Based Asthma Program
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Bartın Unıversity
Malignant Neoplasm of Bronchus or Lung, Unspecified
Cost-consequence Analysis of Parenchymal Stapling Device Versus Hand-sewing for Pulmonary Lobectomy in Lung Disease
The purpose of this study is to compare the efficacy and cost difference of using a parenchymal stapling device versus hand sewing for a pulmonary lobectomy in patients with lung disease (mass or others).
- Trial name
- NCT01575314
- Testing
- stapling device
- Where
- Thailand
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Chiang Mai University
Pulpitis - Irreversible
Clinical and Radiographic Evaluation of Pulpotomy Using Neoputty MTA Versus Pulpectomy Using Metapex in Vital Primary Molars Diagnosed With Symptomatic Irreversible Pulpitis in Children Aged 4 to 9 Years.
itle: Evaluation of Pulpotomy using Neoputty MTA vs. Pulpectomy using Metapex in Children (4-9 years). Objective: Compare clinical and radiographic success of pulpotomy vs.
- Trial name
- NCT06929247
- Testing
- Pulpotomy using Neoputty Mineral Trioxide Aggregate, single visit pulpectomy using metapex
- Volunteers
- 70 people
- Sponsor
- Mohamed Nashaat Mohamed
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