Clinical trials: Randomized-controlled Trial
Hypertension, Renal Transplant
Allopurinol for Renal Transplant Associated Hypertension in Children
To test the hypothesis that lowering serum uric acid will ameliorate hypertension in children after renal transplantation.
- Trial name
- NCT00288171
- Testing
- Allopurinol
- Where
- United States
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Vitiligo, Halo Nevus
Nevus Removal vs. Conservative Treatment in Halo Nevus With Vitiligo: A Randomized Study
This clinical trial aims to compare the efficacy and safety of central nevus removal versus conservative treatment in patients with halo nevus accompanied by non-segmental vitiligo.
- Trial name
- NCT07307534
- Testing
- Central Nevus Excision, The Standardized Medication Regimen
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Xijing Hospital
Prematurity, Respiratory Disease
Caffeine as an Adjuvant Therapy for Late Preterm Infants With Respiratory Distress
Use of caffeine citrate in late-preterm infants with respiratory distress is questionable. Oliphant and colleagues found in a recently published study that caffeine therapy use in late-preterm infants at a loading dose of 20 and…
- Conditions
- Prematurity, Respiratory Disease, Ventilator Lung; Newborn
- Trial name
- CAT/LPT (NCT06026163)
- Testing
- Caffeine citrate
- Where
- 2 sites in Saudi Arabia
- Volunteers
- 134 people
- Sponsor
- Ministry of Health, Saudi Arabia
Prostate Cancer
Clinical Utility Study for MyProstateScore+
This is a national-level research study of urologists. The purpose of this study is to assess the clinical evaluation and management (drug, procedures, counseling and other) of a subset of common patient care indications.
- Trial name
- NCT05525806
- Testing
- Education Materials for MyProstateScore
- Where
- United States
- Volunteers
- 234 people
- Sponsor
- Qure Healthcare, LLC
Stunting in Under-2 Children
Evaluating Bundling of Nutrition-specific Interventions
Background: 1. Burden: The prevalence of stunting among the under-five children in Bangladesh was >55% in 1997, which reduced to 41.9% in 2011.
- Trial name
- NCT02768181
- Testing
- Nutrition-specific Behaviour change communication (BCC), Nutrient supplement to pregnant women (PNS), Nutrienr supplement to children 6m to 2 years
- Where
- Bangladesh
- Volunteers
- 2,880 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Molluscum Contagiosum
A Trial of a Botanical Drug Containing East Indian Sandalwood Oil (EISO) for the Treatment of Molluscum Contagiosum
This trial will examine the safety, tolerability and efficacy of one strength of East Indian sandalwood oil (EISO) in a cream base compared to a placebo for treatment of molluscum contagiosum in pediatric subjects.
- Trial name
- NCT02024581
- Testing
- 10% East Indian sandalwood oil cream
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- ViroXis Corporation
Surgical Glove, Total Knee Arthroplasty
Comparison of Surgical Glove Contamination During Total Knee Arthroplasty Procedure : a Randomized Controlled Trial
Total knee arthroplasty post-op surgical site infection rate about 0.5- 5% Pre-operative , perioperative and post-operative prevention are importance for reduce surgical site infection The prevention of surgical-site infections…
- Conditions
- Surgical Glove, Total Knee Arthroplasty, Contamination Rate
- Trial name
- NCT04308798
- Testing
- Surgical glove changing
- Where
- Thailand
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Khon Kaen University
Acute Chest Syndrome, Sickle Cell Disease
Nitric Oxide Therapy for Acute Chest Syndrome in Sickle Cell Disease Children
Acute chest syndrome is a severe sickle cell disease complication in children requiring blood transfusion therapy to prevent acute respiratory failure and death.
- Trial name
- INNOSTAPED (NCT01089439)
- Testing
- Nitric oxide by inhalation INOMAX
- Where
- France
- Volunteers
- 21 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Malnutrition
Nutrition Supplementation in Hospitalized Patients
Patients with severe malnutrition risk are 7.4 times more likely to die in hospital than well-nourished patients, and carry a 30-day readmission rate of >46%.
- Trial name
- NutriSuP (NCT02632630)
- Testing
- Amino Acids w/Electrolytes in Dextrose, Ensure product, Crystalloid solutions
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Prevention of Dental Caries
Comparative Analysis of Interventions for Prevention of Dental Caries in School Children
A study aims to assess the most effective preventive interventions to address the widespread issue of dental caries, affecting an estimated 2 billion people in permanent teeth and over 500 million children in primary teeth…
- Trial name
- NCT06602765
- Testing
- Tooth brushing, tooth paste containing 1450ppm fluoride
- Where
- Pakistan
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Bahria University
Malocclusion
Micro-osteoperforations and Tooth Movement
The purpose of this study is determine the effect the Microosteoperforation (MOPs) using the miniscrew on the rate tooth movement.
- Trial name
- NCT02473471
- Testing
- Micro-osteoperforation
- Where
- Jordan
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
Physical Exercise
A Randomized Controlled Trial Using Stage-matched Intervention Based on the Transtheoretical Model of Change to Enhance Engaging in Regular Physical Exercise Among High School Female Students.
A randomized controlled trial that uses a Stage-matched intervention based on the Transtheoretical Model of Change to enhance engaging in regular physical exercise among high school female students.
- Trial name
- NCT05938634
- Testing
- Stage-matched interventions
- Where
- Iraq
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Procedural Pain, Procedural Anxiety
Effects of Rain Stick and Musical Egg on Pain, Fear and Anxiety
This research will be conducted in a pre-test-post-test parallel group randomized controlled experimental study model to determine the effects of rain stick and musical egg applied during blood collection on pain, fear and…
- Conditions
- Procedural Pain, Procedural Anxiety, Fear Needles
- Trial name
- NCT06983093
- Testing
- Rain Stick, Musical Egg
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Hakkari Universitesi
High-risk Pregnancy, Hospitalization
LLM-Generated Medical Summaries During Hospitalization to Improve Patient Activation in High-Risk Pregnancies
The goal of this clinical trial is to learn if AI-generated medical summaries help hospitalized pregnant participants better understand and actively participate in their own care.
- Conditions
- High-risk Pregnancy, Hospitalization, Patient Activation, Artificial Intelligence (AI)
- Trial name
- NCT07823517
- Testing
- LLM-Generated Medical Summaries
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Sheba Medical Center
Depresssion
Playback Theatre Program for Adolescents and Youth
The research aims to investigate the effectiveness of playback theatre program on improving mental health for adolescents and youth. This study adopts a multicentre randomized control trial two arms research design.
- Trial name
- Playback (NCT07548463)
- Testing
- Playback theatre program, Waitlist control group
- Where
- Hong Kong
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- City University of Hong Kong
Typical Development, Risk of Dysgraphia
Graphomotor Intervention Program for Handwriting Difficulties Prevention in Preschool Age
12-30% of children present handwriting difficulties, which has negative repercussions on their school career. For this reason, it is fundamental to bet on their prevention.
- Conditions
- Typical Development, Risk of Dysgraphia, Dysgraphia
- Trial name
- NCT03699787
- Testing
- Graphomotor intervention program
- Where
- Portugal
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- University of Évora
Anxiety, Pain
Virtual Reality Pediatric Orthopaedic Outpatient Procedures
The main objective of the study is to evaluate the use of Virtual Reality (VR) in managing pain and anxiety levels during common pediatric orthopaedic outpatient procedures which include: cast application, cast removal, hardware…
- Trial name
- VPRO (NCT03784352)
- Testing
- Virtual Reality
- Where
- Canada
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- British Columbia Children's Hospital
Effect of Drugs, Progression
Famitinib Plus Camrelizumab & Famitinib Alone & Famitinib Plus Ifosfamide in Advanced Osteosarcoma
Results of previous study showed high objective response but short-term activity of anti-angiogenesis tyrosine kinase inhibitors in advanced osteosarcoma.
- Conditions
- Effect of Drugs, Progression, Pediatric Cancer
- Trial name
- NCT04044378
- Testing
- Famitinib, Ifosfamide, Camrelizumab
- Where
- China
- Sponsor
- Peking University People's Hospital
Pain
Pharmacology and Non-pharmacology Approaches in Reducing Children's Pain and Fear During Painful Procedures
This study Will contribute in the knowledge of pediatric nurses during painful procedures such venipuncture
- Trial name
- NCT06326125
- Testing
- TICK-B, TKTX-Cream, TICK-B and TKTX-C
- Where
- Iraq
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Alveolar Bone Loss, Tooth Extraction Status Nos
Assessment of Labial Plate Thickness After Immediate Implant Placement Using Two Different Xenografts in the Esthetic Zone
This randomized clinical trial aims to evaluate labial bone plate changes following immediate implant placement in Type II extraction sockets using two different xenograft materials and de-epithelialized free gingival graft in…
- Conditions
- Alveolar Bone Loss, Tooth Extraction Status Nos, Immediate Implant Placement
- Trial name
- NCT07449806
- Testing
- Immediate Implant Placement with Medpark S1 xenograft, Immediate Implant Placement with bio-Oss xenograft
- Where
- Egypt
- Volunteers
- 26 people
- Sponsor
- Basma Gamal Mohamed Ahmed
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