Clinical trials: Randomized-controlled Trial
Interstitial Lung Disease (ILD), Lung Biopsy
Robotic-Assisted Versus Conventional Bronchoscopy for Cryobiopsy in the Diagnosis of Interstitial Lung Disease
Interstitial lung disease (ILD) often requires histopathological confirmation when high-resolution computed tomography (HRCT) findings are inconclusive.
- Trial name
- RAB-ILD-RCT (NCT07500818)
- Testing
- Robotic-Assisted Bronchoscopy With Cone-Beam CT Guidance, Conventional Bronchoscopy With Fluoroscopy Guidance
- Where
- 2 sites in Switzerland
- Volunteers
- 30 people
- Sponsor
- University of Zurich
Academic Acheivement, Physical Activity
Effects of Physical Activity on Math - an RCT
Background Increased physical activity can improve cognition and academic skills. However due to economic concerns and increasing focus on standardized testing, PA in schools often receives little attention and physical education…
- Trial name
- NCT02488460
- Testing
- Physically active math lessons
- Volunteers
- 545 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Inflammatory Bowel Disease (IBD)
Impact of Transition Programs on Readiness and Quality of Life in IBD
This study is a randomized controlled trial comparing two transition models for adolescents with inflammatory bowel disease (IBD) moving from pediatric to adult care.
- Trial name
- NCT06946810
- Testing
- Combined visits-based transition, Letter-based transition
- Where
- Italy
- Volunteers
- 41 people
- Sponsor
- University of Padova
Caries,Dental, Remineralization
Remineralization Efficacy of Gum Arabic Varnish.
The aim of this study is to evaluate the remineralizing capacity of Gum Arabic varnish and its implementation into clinical practice.
- Conditions
- Caries,Dental, Remineralization, White Spot Lesion
- Trial name
- NCT04422860
- Testing
- Gum Arabic varnish, Proflourid Varnish,VOCO, MI Varnish,GC Japan Inc.
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Cairo University
Type 1 Diabetes Mellitus (T1DM), Motivational Interviewing
Motivational Interviewing and WhatsApp-Based Monitoring for Metabolic Control and Self-Efficacy in Adolescents With T1DM
This clinical study aims to determine the effects of motivational interviewing and social media-based patient monitoring on metabolic control and self-efficacy in adolescents with Type 1 diabetes.
- Conditions
- Type 1 Diabetes Mellitus (T1DM), Motivational Interviewing, Metabolic Control
- Trial name
- NCT06635460
- Testing
- Motivational interviewing, Social media-based patient monitoring
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people
- Sponsor
- Istanbul Medeniyet University
Zygomatic Fractures
Evaluation of Navigation Assisted Reconstruction of Posttraumatic Zygomatic Deformity
Treatment of late deformities following fractures of the orbitozygomaticomaxillary complex can be considered a formidable challenge, even to the skilled surgeon.
- Trial name
- NCT01487018
- Testing
- Navigation Surgery, Traditional Surgery
- Where
- China
- Volunteers
- 103 people
- Sponsor
- Peking University
Apnea of Prematurity, Respiratory Insufficiency
Doxapram Therapy in Preterm Infants (DOXA Trial)
Preterm infants often suffer from apnea of prematurity (AOP; a cessation of breathing) due to immaturity of the respiratory system.
- Trial name
- NCT04430790
- Testing
- Doxapram
- Where
- 24 sites in Belgium, Canada and 1 more
- Volunteers
- 396 people
- Sponsor
- Erasmus Medical Center
Medical Education, Clinical Reasoning
cRCT of AI Agent in Clinital Resoning Training
Traditional medical education has long emphasized one-way transmission of theoretical knowledge, which presents limitations in the systematic cultivation of clinical reasoning skills among medical students.
- Conditions
- Medical Education, Clinical Reasoning, AI Agent
- Trial name
- NCT07624682
- Testing
- AI agent, Study materials
- Where
- China
- Volunteers
- 88 people
- Sponsor
- Peking Union Medical College Hospital
Platelet-Rich Fibrin, Acceleration
The Effect of Multiple Injections of (PRF) on The Rate of Canine Retraction
this clinical trial aims to prove that multiple injections will produce a steady rate of acceleration of orthodontic tooth movement.
- Conditions
- Platelet-Rich Fibrin, Acceleration, Orthodontics
- Trial name
- NCT05766618
- Testing
- Injectable platelet rich fibrin (i-PRF): in acceleration of orthodontic tooth movement
- Where
- Egypt
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Cairo University
Obstructed Labor
Use of Preoperative Sodium Bicarbonate Among Women With Obstructed Labor
The goal of this clinical trial is to determine a universal safe and effective dose of sodium bicarbonate for use among women with Obstructed labour to treat acidosis.
- Trial name
- SoBicOL-II (NCT06579690)
- Testing
- 8.4% sodium bicarbonate solution, 0.9% Normal Saline
- Where
- Uganda
- Volunteers
- 472 people
- Sponsor
- Busitema University
Pain, Distress
Music to Reduce Pain and Anxiety in the Pediatric Emergency Department
Many medical procedures aimed at helping children can cause them pain and distress. If children experience certain levels of pain or distress, it can have long lasting negative effects.
- Trial name
- NCT00761033
- Testing
- music
- Where
- Canada
- Volunteers
- 42 people
- Sponsor
- University of Alberta
Nutrition Disorder, Child
Randomized One-Center Controlled Trial on a Comprehensive Nutritional Intervention for Children With Cerebral Palsy and ASD
The study is a prospective, single-center, randomized controlled trial that will be conducted at the Medical University of Varna.
- Trial name
- Nutrilect (NCT06065904)
- Testing
- Nutrilect
- Volunteers
- 200 people
- Sponsor
- Silviya Pavlova Nikolova, PhD
Dyspnea, Unexplained Chronic Dyspnea
Establishing Clinical Utility for a New Diagnostic Test for Patients With Shortness of Breath
This study will collect high-quality data on how practicing specialist physicians, specifically cardiologists and pulmonologists, across the U.S.
- Trial name
- NCT04693793
- Testing
- Education Materials and Janssen Test
- Where
- United States
- Volunteers
- 219 people, healthy volunteers welcome
- Sponsor
- Qure Healthcare, LLC
Adolescent - Emotional Problem, Suicide and Self-harm
DBT-Based Parenting Intervention for Parents of Youth at Risk for Suicide
The purpose of the present study is to conduct a pilot randomized clinical trial (RCT) of an 8-10 session DBT-based parenting intervention (DBT PI) plus standard Dialectical Behavior Therapy delivered in the context of an…
- Conditions
- Adolescent - Emotional Problem, Suicide and Self-harm, Parenting
- Trial name
- NCT04132284
- Testing
- DBT-Based Parenting Intervention, Treatment as Usual
- Where
- United States
- Volunteers
- 91 people
- Sponsor
- Stanford University
Mood Disorders, Prodromal Symptoms
MBCT and CBT for Youth at High Risk for Mood and Psychotic Disorders: a Randomized Controlled Trial
The present study is a randomized controlled trial comparing the efficacy and acceptability of CBT and MBCT group-based interventions adapted for young people at elevated risk for mood or psychotic disorder onset or relapse.
- Conditions
- Mood Disorders, Prodromal Symptoms, Bipolar Disorder, Parents
- Trial name
- NCT05070052
- Testing
- cognitive behavioral therapy, mindfulness-based cognitive therapy
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- University of California, Los Angeles
Childbirth
THE EFFECT OF 360° VIDEO-ASSISTED TRAINING ON VERTICAL BIRTH POSITIONS IN PRIMIPAROUS WOMEN ON FEAR OF CHILDBIRTH, SELF-EFFICACY IN CHILDBIRTH, SATISFACTION WITH CHILDBIRTH, AND PERINEAL TRAUMA: A RANDOMIZED CONTROLLED TRIAL
This randomized controlled trial aims to evaluate the effects of 360-degree video-supported upright birth position education on fear of childbirth, childbirth self-efficacy, birth satisfaction, and perineal trauma among…
- Trial name
- NCT07820904
- Testing
- 360° Video-Supported Upright Birth Positions Education
- Where
- Turkey (Türkiye)
- Volunteers
- 92 people
- Sponsor
- Bitlis Eren University
Diarrhea Toddler
The Impact of Pre-emptive Home Delivery of ORS + Zinc on Treatment for Child Diarrhea
The aim of this clustered randomized controlled trial is to evaluate whether free and pre-emptive distribution of Oral Rehydration Salts (ORS) and Zinc at home increases the use of ORS to treat diarrhea cases among children under…
- Trial name
- NCT06444633
- Testing
- Community Sensitization + Household visit + Information + Free pre-emptive distribution of ORS+Zinc
- Where
- Nigeria
- Volunteers
- 102,650 people, healthy volunteers welcome
- Sponsor
- RAND
Antibiotic Associated Diarrhea, Upper Respiratory Tract Infection
Effectiveness of Saccharomyces Boulardii in Prevention of Antibiotic Associated Diarrhea
Antibiotic-associated diarrhea (AAD) is a common adverse effect in pediatric patients receiving broad-spectrum antibiotics such as co-amoxiclav for upper respiratory tract infections (URTI).
- Trial name
- NCT07785206
- Testing
- Co-amoxiclav, Saccharomyces boulardii
- Where
- Pakistan
- Volunteers
- 88 people
- Sponsor
- University of Child Health Sciences and Children's Hospital, Lahore
Food Insecurity
Impact of Healthy Food Subsidies on Diet Quality and Food Security
The British Columbia Farmers' Market Nutrition Coupon Program (FMNCP) provides lower-income households with coupons to purchase healthy foods at farmers' markets.
- Trial name
- NCT06992947
- Testing
- Healthy food subsidy: $27/household/week, Healthy food subsidy: $54/household/week, Healthy food subsidy: $81/household/week
- Where
- Canada
- Volunteers
- 538 people
- Sponsor
- University of Calgary
Stress, Psychological, Social Isolation
Stay Healthy In Nature Everyday: Family Nature Outings in a Low Income Population
The SHINE study is a randomized controlled study of the effect of a park-based family support group on multiple outcomes (including stress and physical activity) in a low income population.
- Conditions
- Stress, Psychological, Social Isolation, Physical Activity
- Trial name
- SHINE (NCT02623855)
- Testing
- Family outings, Park prescription, Pedometry
- Where
- United States
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- UCSF Benioff Children's Hospital Oakland
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