Clinical trials: Randomized-controlled Trial
Anxiety Disorder
Initial Evaluation of a Stepped Care Model for Treating Mild to Moderate Childhood Anxiety in Primary Care
Objectives: In the past ten years in Sweden, a new form of primary care units called first line mental health (FLMH) has been implemented to improve mental health services for children and adolescents.
- Trial name
- NCT05686512
- Testing
- Step-by-Step, Cool Kids
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Region Stockholm
Pulp Disease, Dental, Pulp Therapy in Primary Molars
Oxymetazoline Versus Sodium Hypochlorite as Hemostatic Agents in MTA Pulpotomy of Primary Molars
This study aims to evaluate clinical and radiographic success of oxymetazoline versus sodium hypochlorite as hemostatic agents in MTA pulpotomy of primary molars.
- Conditions
- Pulp Disease, Dental, Pulp Therapy in Primary Molars, Pulpitis - Reversible, Pulp Inflammation
- Trial name
- OXY - MTA (NCT07675330)
- Testing
- Oxymetazoline 0.05% nasal solution, Sodium Hypochlorite Solution
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Response Rates
Contacting Authors to Retrieve Individual Patient Data
The objective of this study is to examine the impact of incentivizing authors of RCTs that are eligible for a systematic review and meta-analysis, versus usual contact strategies to obtain original IPD
- Trial name
- NCT02569411
- Testing
- Financial Incentive
- Volunteers
- 129 people
- Sponsor
- Unity Health Toronto
Orthodontic Discomfort, Pain, Orofacial
Comparison of Patient-reported Pain After Initial Archwire Placement
Three different types of 'archwires' can be used in Orthodontic treatment, wire choice is decided by treating Orthodontist based on professional preference since research shows that all types are equally effective.
- Trial name
- Archwires (NCT03906422)
- Testing
- 3M Unitek 0.016 orthodontic archwire, Device: 0.016" Ormco 27oC NiTi orthodontic archwire, Device: 0.016" Ormco 35oC NiTi orthodontic archwire
- Where
- United States
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Social Anxiety Disorder, Separation Anxiety Disorder
Stepped Versus Stratified Care for Anxiety Disorders in Youth
The goal of this clinical trial is to compare stepped care to stratified care as overall healthcare models for children and adolescents aged 8-17 with anxiety disorders.
- Conditions
- Social Anxiety Disorder, Separation Anxiety Disorder, Specific Phobia, Panic Disorder
- Trial name
- NCT06942429
- Testing
- Internet-delivered cognitive-behavioral therapy, Personalized in-person cognitive-behavioral therapy
- Where
- Sweden
- Volunteers
- 556 people
- Sponsor
- Region Skane
Osteoarthritis
The Role of Intra-Operative Intracapsular Blocks in Post-Operative Pain Management Following Total Knee Arthroplasty
The purpose of this study is to use a new combination of anesthesia techniques in an attempt to minimize early pain after surgery and improve the patient's ability to participate more fully with physical therapy.
- Trial name
- NCT00620828
- Testing
- Ropivicaine 0.5%
- Where
- United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Duke University
Bracket Failure, Bracket Bonding
Comparison of Bond Failure Rate of Orthodontic Brackets Bonded With V-Prep and Resin-Modified Glass Ionomer Cement Versus Conventional Acid-Etch Composite Resin
Ethical approval will be obtained by the FUSH and informed consent will be obtained from individual patients/guardians in writing.
- Conditions
- Bracket Failure, Bracket Bonding, RMGIC, Conventional Bracket Bonding
- Trial name
- NCT07828431
- Testing
- V-Prep and Resin-Modified Glass Ionomer Cement, Conventional Acid-Etch Composite Resin
- Where
- Pakistan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Foundation University Islamabad
Asthma
Dose-Ranging Study of LQ036 Single-Domain Antibody Nebulization Solution in Poorly Controlled Asthma
What is the goal of this study? The goal of this clinical trial is to find out whether the study drug LQ036 (a nebulized solution taken by inhaling through a nebulizer) works to improve lung function and asthma control in people…
- Trial name
- NCT07589439
- Testing
- LQ036
- Where
- China
- Volunteers
- 216 people
- Sponsor
- Shanghai Novamab Biopharmaceuticals Co., Ltd.
Chronic Pain
Study to Evaluate the Efficacy of Dronabinol (Marinol) as Add-On Therapy for Patients on Opioids for Chronic Pain
The purpose of this research study is to determine if Marinol alleviates pain in patients with chronic pain who are currently taking opioids.
- Trial name
- NCT00153192
- Testing
- Marinol (dronabinol)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Brigham and Women's Hospital
Patient Safety, Fall
THE EFFECT OF STANDARD PATIENT AND WEB-BASED SIMULATION ON FALL KNOWLEDGE AND ATTITUDES AMONG NURSING STUDENTS
The most fundamental principle of any healthcare service is "First, do no harm." No one should be harmed in healthcare services.
- Conditions
- Patient Safety, Fall, Simulation Edication
- Trial name
- NCT07391111
- Testing
- Standardized patient, web-based simulation
- Where
- Turkey (Türkiye)
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- ESRA ERTUĞRUL
Pregnancy
The Effect of Journaling on Prenatal Attachment in Pregnant Women
Summary Scientific Merit: Pregnancy is one of the periods in which a woman experiences the most intense physical and psychological changes.
- Trial name
- NCT07798076
- Testing
- journaling during pregnancy, routine care
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Resuscitation
Newborn Ventilation in the Delivery Room: Could it be Improved With a T-piece Resuscitator?
A multicenter cross-over cluster randomized controlled trial protocol study in newborn infants ≥ 26 weeks gestational age requiring assisted ventilation (positive pressure ventilation [PPV]) for resuscitation in the delivery room…
- Trial name
- NCT00443118
- Testing
- T-piece resuscitator Neopuff TM, Self Inflating Bag with PEEP, Self Inflating Bag without PEEP
- Where
- 11 sites in United States, Argentina and 3 more
- Volunteers
- 1,032 people
- Sponsor
- Edgardo Szyld
Anxiety, Digital Eye Strain
Reducing Eye Strain and Anxiety Using a Digital Intervention During Online Learning Class Recess Among Children at Home: A Randomized Controlled Trial
The primary aim of the current study is to conduct a cluster-randomized control trial to evaluate the effectiveness of a novel digital intervention in reducing anxiety and digital eye strain compared to usual care among Chinese…
- Trial name
- RESILIENT (NCT04309097)
- Testing
- Digital intervention, Information-only intervention
- Where
- China
- Volunteers
- 954 people
- Sponsor
- Sun Yat-sen University
Medical Education, Simulation
Does Teaching Before or After Simulation Improve Learning?
The goal of the randomized educational intervention study is to test whether simulation preceding didactic teaching leads to improved knowledge and performance retention compared to a didactic lecture proceeding simulation for…
- Trial name
- NCT06092320
- Testing
- Simulation on Pediatric Status Epilepticus, Didactic Lecture on Pediatric Status Epilepticus
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University of British Columbia
Spastic Diplegia, Cerebral Palsy
Effect of Core Stability Training on Segmental Trunk Control and Quality of Life in Children with Cerebral Palsy
Spastic diplegia is a common shape of cerebral palsy that significantly affects trunk control and quality of life in children. Core stability training (CST) has been utilized as a potential intervention to improve the trunk…
- Trial name
- NCT06822296
- Testing
- Physical Therapy, Designed rehabilitation program
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Tourette Syndrome in Adolescence
Is Medicinal Cannabis an Effective Treatment for Tourette Syndrome in Adolescents? a Pilot Study
This is a single site, pilot double-blind, randomized, placebo-controlled, cross-over study of 10 participants comparing medicinal cannabis (THC:CBD 10:15 oil) with placebo in reducing tics in adolescents aged 12 - 18 years with…
- Trial name
- NCT05184478
- Testing
- Medicinal cannabis (MC): THC 10mg/mL : CBD 15mg/mL, manufactured by Cann Group Ltd.
- Where
- Australia
- Volunteers
- 10 people
- Sponsor
- Murdoch Childrens Research Institute
Induction of Labor Affected Fetus / Newborn
Dexamethasone and Induction of Delivery
This study aims to evaluate the effect of intravenous injection of a single dose of dexamethasone in shortening the duration interval between initiation of labor induction and delivery of the fetus in primigravida full-term…
- Trial name
- NCT03658590
- Testing
- Dexamethasone, Distilled Water
- Where
- Egypt
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- samar sayed el sayed
Pediatric Crohn's Disease
Efficacy and Safety of Top-down Therapy in Pediatric Crohn's Disease
Crohn's disease (CD) is an incurable debilitating disorder affecting an increasing number of children. The etiology remains elusive, but a genetically determined aberrant immune response against microbiota appears to be…
- Trial name
- NCT01752790
- Testing
- Top-down, Step-up
- Where
- Italy
- Sponsor
- University of Roma La Sapienza
ACL Injury
Influence of Combined Double-Bundle ACL Reconstruction With Lateral Retinacular Release to Prevent Patellofemoral Malalignment in Isolated ACL Rupture
Anterior knee pain which might be due to patellofemoral malalignment is an inevitable post operative complication after an ACL reconstruction (ACLR).
- Trial name
- NCT06004297
- Testing
- ACL reconstruction
- Where
- Indonesia
- Volunteers
- 100 people
- Sponsor
- Universitas Indonesia
Health Literacy, Anesthesia
Effect of Educational Intervention on Children's Anxiety
The aim of this randomized controlled trial is to evaluate the effectiveness of an educational health game intervention for children undergoing anesthesia from the perspective of children's anxiety.
- Conditions
- Health Literacy, Anesthesia, Anxiety, Fear
- Trial name
- MINA (NCT06600113)
- Testing
- Education and teaching of coping strategies
- Where
- Iceland
- Volunteers
- 150 people
- Sponsor
- University of Iceland
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