Clinical trials: Randomized-controlled Trial
Pediatric Preoperative Anxiety, Pediatric Coping
Preparing Children for Anesthesia With an Educational Pop-Up Book
The study evaluated an educational pop-up book about general anesthesia induction as an interactive, child-focused preoperative education resource for pediatric patients undergoing outpatient surgery.
- Trial name
- NCT04796077
- Testing
- Pop-Up Book
- Where
- United States
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Children's Healthcare of Atlanta
Atopic Dermatitis, Eczema
Cardamom and Topical Roseomonas in Atopic Dermatitis
Background: Atopic dermatitis (AD), also called eczema, is a chronic skin condition. AD can make skin dry and itchy, and sometimes it can lead to serious health problems, such as asthma, food allergies, eye infections, and sleep…
- Trial name
- NCT06096857
- Testing
- Roseomonas mucosa (RSM2015) and Cardamom seeds
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Apicomarginal Defects
Evaluate the Effect of Graft and Membrane on Healing of Apicomarginal Defects
This study will compare the effect of guided tissue regeneration using a mixture of autograft and PRF covered with a collagen membrane as compared to the membrane alone in the healing of apicomarginal defects.
- Trial name
- NCT04366700
- Testing
- Periapical surgery with autograft and collagen membrane, Periapical surgery with collagen membrane
- Where
- India
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Child Obesity, Cardiometabolic Health
Evaluating the Impact of a School-based Fruit and Vegetable Co-op on Cardiometabolic Child and Parents Health in a Persistent Poverty Area
The purpose of this study is to examine the effects of the (Brighter Bites (BB) intervention compared to a wait-list control group 9 months after the intervention on changes in primary child outcomes (HbA1c, and vegetable…
- Trial name
- NCT06570707
- Testing
- Brighter Bites
- Where
- United States
- Volunteers
- 720 people
- Sponsor
- The University of Texas Health Science Center, Houston
Distal Humerus Fracture
Elbow Hemiarthroplasty Versus Total Elbow Arthroplasty for Irreparable Distal Humeral Fractures
Distal humeral fractures can be difficult to treat, in particular when the joint surface is affected (intra-articular fractures).
- Trial name
- NCT03596736
- Testing
- Elbow Hemiarthroplasty, Total Elbow Arthroplasty
- Where
- 3 sites in Sweden
- Volunteers
- 42 people
- Sponsor
- Linkoeping University
Failed or Difficult Intubation
Hybrid Intubation Technique for Difficult Airway Children
To compare two hybrid techniques, flexible bronchoscopy-guided intubation with a video laryngoscope and flexible bronchoscopy-guided intubation with a laryngeal mask, that have recently shown promise as a way to increase…
- Trial name
- NCT06058221
- Testing
- simultaneous videolaryngoscopy, supraglottic airway
- Where
- South Korea
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Postoperative Pain
Effect of a Sciatic Block (SNB) Combined With a Continuous Femoral Block (CFNB) on Pain Scores After Knee Arthroplasty
The purpose of this study is to determine if the addition of a sciatic nerve block (SNB) to a continuous femoral nerve block (CFNB) improves post-operative analgesia after knee arthroplasty.
- Trial name
- NCT01337115
- Testing
- SNB plus CFNB, CFNB
- Where
- Portugal
- Volunteers
- 50 people
- Sponsor
- Centro Hospitalar do Porto
Healthy Infants
Efficacy of a New Infant Formula Composition on Gut Health in Infants
The aim of this study is to investigate potential health benefits of the experimental formula. The main objective is whether the experimental formula elevates the relative abundance of Bifidobacterium in stool samples after 10…
- Trial name
- NCT07242508
- Testing
- Infant Formula, Infant Formula with bioactive ingredients
- Where
- Bulgaria
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- FrieslandCampina
Cesarean Scar Defect
Double Vers Single in Cesarean Incision
To assess the effect of single versus double layer closure of caesarean scar on the residual myometrium on the short \& intermediate term.
- Trial name
- NCT05276518
- Testing
- Closure of cesarean section incision
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ain Shams Maternity Hospital
Type 1 Diabetes
Comparison of a Twice Daily Versus a Three Times Daily Insulin Regimen in Children With Type 1 Diabetes
The purpose of this study is to determine whether there is a difference in blood sugar control (as measured by hemoglobin A1c (HA1c)), in children given twice daily insulin injections incorporating a new long acting insulin…
- Trial name
- NCT00522210
- Testing
- Detemir, Novolin NPH or Humulin N
- Where
- Canada
- Volunteers
- 18 people
- Sponsor
- University of Calgary
Maternal Death, Neonatal Death
Evaluating the Effects of SMS Text Messaging Support System Among Frontline Health Workers in Ghana
Introduction Maternal and neonatal mortality continue to be to be prominent public health issues in sub Saharan Africa including Ghana, with slow progress made towards attainment of Millennium Development Goals (MDG) 4 \& 5.
- Conditions
- Maternal Death, Neonatal Death, Postpartum Haemorrhage, Pre-eclampsia
- Trial name
- Accelerate (NCT02468310)
- Testing
- Maternal and neonatal emergency protocols
- Where
- Ghana
- Volunteers
- 65,831 people, healthy volunteers welcome
- Sponsor
- Hannah Brown Amoakoh
Dengue
Impact of Project Wolbachia - Singapore on Dengue Incidence
The study is a cluster-randomised controlled trial set in Singapore, to assess if the deployment of male Wolbachia-infected Aedes aegypti mosquitoes can reduce dengue incidence in intervention clusters.
- Trial name
- NCT05505682
- Testing
- Biological (Male Wolbachia-infected Aedes aegypti)
- Where
- Singapore
- Volunteers
- 724,428 people
- Sponsor
- National Environment Agency, Singapore
Myopia, Ear Acupressure Pellets
Effects of Auricular Point Pressing With Pellets in Children With Insufficient Hyperopia Reserve
This project aims to address the trend of early onset and high myopia among children in China by focusing on insufficient hyperopia reserve, a key early warning indicator for myopia.
- Conditions
- Myopia, Ear Acupressure Pellets, Hyperopia Reserve, Low-concentration Atropine Eye Drops
- Trial name
- NCT07475585
- Testing
- Ear acupoint pressure pellet intervention group, Atropine intervention group, Joint intervention Group
- Volunteers
- 380 people, healthy volunteers welcome
- Sponsor
- Fangbiao Tao
Strength Training Effects, HFrEF - Heart Failure With Reduced Ejection Fraction
Eccentric Muscle Training in Cardiac Rehabilitation
The goal of this interventional study is to assess the training effects in a training schedule in which eccentric overload training and eccentric cycle training are used.
- Trial name
- NCT07636343
- Testing
- eccentric bike training, eccentric overload training, aerobic treadmill training
- Where
- Belgium
- Volunteers
- 3 people
- Sponsor
- University Hospital, Antwerp
Cold-water Immersion, Protein-carbohydrates Supplementation
Effects on CK, RPE, VAS Scale and Physical Performance of Three Recovery Methods in Elite Basketball Players
The aim of this study was to compare the effects of cold water intermittent ion (CWI), carbohydrate and protein supplementation (SUPPL), and active recovery (ACT) on creatine kinase (CK), perceptual and performance markers of…
- Conditions
- Cold-water Immersion, Protein-carbohydrates Supplementation, Active Recovery, Placebo
- Trial name
- NCT05805540
- Testing
- Cold-water immersion, Protein-carbohydrates supplementation, Active recovery
- Where
- Spain
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Cadiz
Periapical Lesion
Effect of Piezoelectric Device on Intraoperative Hemorrhage Control and Quality of Life
Most osteotomies and apicoectomies in periapical surgeries are performed by surgical carbide or diamond burs. But greater pressure is applied during cutting which causes more thermal and mechanical damage to the bone.
- Trial name
- NCT06240182
- Testing
- conventional surgery, piezoelectric device
- Where
- India
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Acute Pancreatitis
The Effect of Dietary Fat Content on the Recurrence of Pancreatitis
This trial aims to test the effects of two different diets on the recurrence of acute pancreatitis, and acute pancreatitis associated mortality.
- Trial name
- EFFORT (NCT04761523)
- Testing
- Dietary intervention: reduced fat diet, Dietary intervention: standard healthy diet
- Where
- Hungary
- Volunteers
- 384 people
- Sponsor
- University of Pecs
Class III Skeletal Malocclusion
Comparative 3D Assessment of Class III Malocclusion Treatments
This clinical trial compares three different treatment methods used to correct jaw problems in children with Class III malocclusion (a condition where the lower jaw is positioned forward relative to the upper jaw).
- Trial name
- CLASSIII-3D (NCT07179354)
- Testing
- Rapid Maxillary Expansion with Face Mask (RME/FM), Mini Maxillary Protractor (MMP), Modified Splint with Elastics and Chin Cup (Modified SEC III)
- Where
- Turkey (Türkiye)
- Volunteers
- 55 people
- Sponsor
- TC Erciyes University
Facial Pain, Headache
Effects of Photobiomodulation With Superpulsed Laser and Dual Wavelengths in Children and Adolescents
This randomized clinical trial evaluates the effects of photobiomodulation with a superpulsed diode laser (810 + 980 nm) on orofacial pain and tension-type headache in children and adolescents.
- Trial name
- NCT07031505
- Testing
- Active Photobiomodulation
- Volunteers
- 60 people
- Sponsor
- University of Nove de Julho
Gingival Recession
Effect of Orthodontic Treatment on the Stability of Pre-Orthodontic Recession Coverage
This study attempts to assess the effect of orthodontic treatment on the stability of pre-orthodontic recession coverage by connective tissue graft- a randomized controlled clinical trial and thus facilitate better evidence based…
- Trial name
- NCT03886051
- Testing
- Connective Tissue Graft before Orthodontic treatment, Orthodontic treatment only
- Where
- India
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
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