Clinical trials: Reading Disorder
Rare Diseases, Genetic Predisposition
Mitochondrial Diseases - Long-read Genome and Transcriptome Sequencing in Cases Unresolved After Short-read Genomics
The MiDiSeq project will enroll 20 unresolved index patients with suspected mitochondrial disease prioritized for genomic analysis.
- Trial name
- NCT03962452
- Testing
- Next Generation Sequencing (NGS)
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- University Hospital Tuebingen
Visual Acuity, Refractive Errors
Pre-symptomatic Screening of Visual Acuity in Pre-school Students
The present research process is a prospective, non-interventional clinical study that will be conducted -under the auspices of the Democritus University of Thrace (DUTH)- in the pre-school students of the city of Alexandroupolis…
- Conditions
- Visual Acuity, Refractive Errors, Low Vision, Vision Disorders
- Trial name
- NCT05835193
- Testing
- Diagnostic Test: Distance Visual Acuity Examination
- Where
- Greece
- Volunteers
- 1,098 people, healthy volunteers welcome
- Sponsor
- Democritus University of Thrace
Developmental Reading Disorder, Dyslexia
Developmental Dyslexia and Functional Maturation of Auditory Cortex
Developmental dyslexia is a frequent learning disability. The aim of this study is to compare auditory evoked cortical responses to syllables and tones in developmental dyslexia and controls (paired with age, gender).
- Trial name
- DYS-AUT (NCT00245804)
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Tours
Dyspnea
Artificial Intelligence to Improve Physicians' Interpretation of Chest X-Rays in Breathless Patients
Identifying the cause of breathlessness in acute patients in the emergency department is critical and challenging. The chest X-ray is central but challenging to read for non-radiologist physicians.
- Trial name
- XRAI (NCT05117320)
- Testing
- AI support
- Where
- Denmark
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Bispebjerg Hospital
Metastatic Bone Tumor
Automated Detection of Metastatic Bone Disease on Bone Scintigraphy Scans
Bone scintigraphy scans are two dimensional medical images that are used heavily in nuclear medicine. The scans detect changes in bone metabolism with high sensitivity, yet it lacks the specificity to underlying causes.
- Trial name
- NCT05110430
- Testing
- Deep learning based detection of metastatic bone disease on bone scintigraphy scans.
- Where
- Netherlands
- Volunteers
- 2,365 people
- Sponsor
- Maastricht University
Dyslexia
Sensory Integration Therapy in Children With Dyslexia
The aim of this study is to examine the sensory and functional effects of sensory integration therapy in children with dyslexia according to the Model of Human Occupation (MOHO).
- Trial name
- Dyslexia (NCT04740853)
- Testing
- Sensory Integration Therapy+Special Education
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people
- Sponsor
- Biruni University
Preoperative Anxiety
Augmented Reality Applied Book Reading in the Preoperative Period
Non-pharmacological methods such as multimedia applications and visual and auditory technological tools are used to create a more enjoyable experience by reducing children's fear and anxiety and distracting them in the…
- Trial name
- NCT06399016
- Testing
- augmented reality book, book
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Manisa Celal Bayar University
Developmental Dyslexia, Developmental Language Disorder
Dynamic Assessment of the Risk for Language and Reading Disorders in Monolingual and Multilingual Children
The project represents the completion of a part of the recently concluded European project MultiMind, in which a computer platform called MuLiMi was developed and validated.
- Trial name
- NCT06937255
- Testing
- computerized Dynamic Assessment
- Where
- Italy
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea
Neurofibromatosis Type 1
Vision, Attention and Reading in Neurofibromatosis Type 1 (NF1) Children
The present project will therefore focus upon those processes related to visual attention and perceptual abilities and on their potential to explain reading behavior and reading problems in NF1.
- Trial name
- NCT03518710
- Testing
- Neuropsychological evaluation, Evaluation of the reading assistance technique
- Where
- France
- Volunteers
- 15 people
- Sponsor
- University Hospital, Toulouse
Reading Disability
Executive Function in Early Childhood
Despite the fact that a substantial number of school age children struggle with both reading and math acquisition, the brain mechanisms of the overlapping aspects of reading and math skills, thought in part to be linked via…
- Trial name
- NCT03713125
- Testing
- Reading Tutoring
- Where
- United States
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Dyslexia
Maturation of Auditory Processing in Children With Dyslexia Compared to Average-reading Children
The hypothesis of central auditory processing disorders has been advanced to explain the anomalies of the grapheme/phoneme combination in some dyslexia.
- Trial name
- ASTRAUCOLE (NCT02345876)
- Testing
- no intervention
- Where
- 3 sites in France
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Dyslexia, Adolescent
Usefulness of an Assistive Technology Training Program for Adolscents With Dyslexia
Specific Written Language Disorders (SWLD) are severe and lasting impairments in the development of written language that affect approximately 10% of the school-age population.Concerned patients don't have any intellectual…
- Trial name
- FormONC (NCT05636813)
- Testing
- Training
- Where
- France
- Volunteers
- 12 people
- Sponsor
- University Hospital, Caen
Speech Articulation Disorder, Developmental Articulation Disorder
Randomized Clinical Trial of Phonological Interventions
Recent research reveals genetic and symptomatic overlap among children with speech sound disorders (i.e., those who (misarticulate more sounds than would be expected for their age) and children with dyslexia (i.e., those who…
- Conditions
- Speech Articulation Disorder, Developmental Articulation Disorder, Phonological Impairment, Dyslexia
- Trial name
- ECRIP (NCT00818428)
- Testing
- Speech Production Intervention, Speech Perception Intervention, Articulation Parent Group
- Where
- 2 sites in Canada
- Volunteers
- 96 people
- Sponsor
- McGill University
Language Disorder, Healthy
Language Stimuli Screening in Children
This study will determine baseline language skills in children 4 to 8 years old. The data will be used to design studies using functional magnetic resonance imaging (fMRI) to identify what areas of the brain in children are…
- Trial name
- NCT00016796
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
ADHD, Reading/Writing Disorder
Omega-3/Omega-6 Fatty Acids for Attention-Deficit/Hyperactivity Disorder (ADHD): A Trial in Children and Adolescents
Objective: To assess whether supplementation with Omega 3/6 fatty acids (eye q®) was effective in the treatment of ADHD and its diagnostic subtypes and comorbid conditions, in children and adolescents.
- Trial name
- NCT01219309
- Testing
- Omega 3/6 fatty acids
- Volunteers
- 82 people
- Sponsor
- Göteborg University
Dyslexia, Developmental
Poly-unsaturated Fatty Acids and Developmental Dyslexia
Poly-unsaturated fatty acids (PUFAs) represent a component of lipids that covers a relevant role in human diet and biological functions such as provision of energy, functionality of cell membranes and tissue metabolism.
- Trial name
- NCT04287530
- Testing
- Poly-unsaturated fatty acids supplementation, Neuropsychological intervention
- Where
- 2 sites in Italy
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea
Dyslexia, Gait Disorders, Neurologic
Dynamic Gait Index in Children With Dyslexia
The aim of the present study is to investigate reliability in dyslexic children and compare it with healthy peers.
- Trial name
- NCT04235465
- Testing
- Dynamic Gait Index
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Marmara University
Dyslexia
Dyslexia, Motor Control and Proprioception
The investigators hypothesize that children with dyslexia present proprioceptive disorders and the purpose of the present study is to better understand relationships between motor control, proprioception and academic learnings.
- Trial name
- NCT03364010
- Testing
- Evaluation of proprioception, Evaluation of motor learning, Evaluation of written language
- Where
- France
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Learning Disorders, Dyslexia
Efficacy of a Two-Year Intensive Reading Intervention for Middle School English Learners With Reading Difficulties
This study investigates the efficacy of a reading comprehension intervention for English learners in Grades 6 and 7 with reading difficulties.
- Trial name
- TCLD (NCT03695068)
- Testing
- RISE Intervention
- Where
- 2 sites in United States
- Volunteers
- 840 people
- Sponsor
- University of Houston
Reading Disability
University of Washington Reading & Dyslexia Research Program
Subjects are recruited for a pre-kindergarten education program focusing on early literacy skills. Primary outcomes are improvement in letter knowledge and changes in brain response to text.
- Trial name
- NCT03945097
- Testing
- preK
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- University of Washington