Clinical trials: Reconstructive Surgical Procedure
LET, ACL Reconstruction
Long-term Follow up of the Stability 1 Trial
From 2014-2017, across 7 Canadian and 2 European sites, we randomized 618 patients at high-risk of re-injury, to anterior cruciate ligament reconstruction (ACLR) with or without a lateral extraarticular tenodesis (LET) and…
- Conditions
- LET, ACL Reconstruction, Osteoarthritis (OA) of the Knee
- Trial name
- STABILITY LTF (NCT06885372)
- Testing
- Lateral Extra-Articular Tenodesis (LET), ACL Reconstruction
- Where
- 8 sites in Canada, United Kingdom
- Volunteers
- 510 people
- Sponsor
- Western University, Canada
Patients Undergoing Microvascular Surgery
Use of Bemiparine as a Prophylactic Antithrombotic Agent, in Patients Undergoing Microsurgery for Head and Neck Reconstruction
A comparative study to reveal if the use of Bemiparine (Hibor) versus Enoxaparin (Clexane) as an antithrombotic agent, shows an advantage on the rate of thrombotic and haemorrhagic events in microsurgicals free flaps during head…
- Trial name
- NCT02808273
- Testing
- Bemiparine
- Where
- Spain
- Volunteers
- 78 people
- Sponsor
- Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal
Complex Digital Injuries
Reconstruction of a Neurocutaneous Defect of the Proximal Phalanx With a Heterodigital Arterialized Nerve Pedicle Flap
Complex digital injuries involving soft tissue loss and digital nerve defect pose challenging problems for hand surgeons. This study uses the heterodigital arterialized nerve pedicle flap including the dorsal branch of the…
- Trial name
- NCT01837407
- Testing
- Composite Flap
- Where
- China
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- The Second Hospital of Tangshan
Anterior Cruciate Ligament Reconstruction
Safety of OMS103HP in Patients Undergoing Anterior Cruciate Ligament (ACL) Reconstruction
OMS103HP is being developed for improvement in knee function following ACL reconstruction. Secondary benefits being evaluated include reduced postoperative pain, improvement in knee motion and earlier return to work.
- Trial name
- NCT00245271
- Testing
- OMS103HP, Vehicle
- Where
- 10 sites in United States
- Volunteers
- 480 people
- Sponsor
- Omeros Corporation
Clavicle Fracture
Reconstruction Plate Compared With Flexible Intramedullary Nailing for Midshaft Clavicular Fractures
The purpose of this study is to compare the clinical and radiographic results of patients with midshaft clavicular fractures treated with plates or intramedullary flexible nails fixation.
- Trial name
- NCT01410032
- Testing
- Plate fixation, ESIN
- Where
- Brazil
- Volunteers
- 59 people
- Sponsor
- University of Sao Paulo
Pain, Postoperative, Opioid Use
Impact of Counseling and Education on Opioid Consumption After ACL Reconstruction
Research question: Does an opioid limiting pain management counseling and education program result in decreased opioid consumption and improved pain control compared to traditional pain management programs after anterior cruciate…
- Trial name
- CARE (NCT04885231)
- Testing
- Perioperative Pain Management Education and Counseling
- Where
- United States
- Volunteers
- 121 people
- Sponsor
- University of Maryland, Baltimore
Ulcerative Colitis, Primary Sclerosing Cholangitis
Surgical Reconstruction in Ulcerative Colitis With Primary Sclerosing Cholangitis
Primary sclerosing cholangitis (PSC) occurs in approximately 10 % of patients with ulcerative colitis (UC), but the outcome of reconstructive surgery is not clear.
- Conditions
- Ulcerative Colitis, Primary Sclerosing Cholangitis, Pouchitis, Complications
- Trial name
- NCT01798953
- Where
- Sweden
- Volunteers
- 175 people
- Sponsor
- Sahlgrenska University Hospital
Alveolar Ridge Abnormality
Evaluation of Platelet Rich Fibrin / Biphasic Calcium Phosphate Effect Versus Autogenous Bone Graft on Reconstruction of Alveolar Cleft
P- Maxillary alveolar cleft defects I- Platelet-rich fibrin (PRF) combined with biphasic calcium phosphate (BCP) C- Autogenous bone graft O- Outcome measure : bone height, bone volume, hospital stay, operation duration T- 6…
- Trial name
- NCT03302429
- Testing
- PRF/ BCP, Autogenous bone graft
- Where
- Egypt
- Volunteers
- 18 people
- Sponsor
- Cairo University
Alveolar Cleft Grafting
Alveolar Cleft Reconstruction Using Bone Marrow Aspirate Concentrate and Allograft vs Iliac Cancellous Bone.
radiographic and clinical assessment of alveolar cleft grafting using Allograft mixed with BMAC compared to the standard protocol of anterior iliac crest cancellous bone grafting
- Trial name
- BMAC (NCT06356870)
- Testing
- BMAC MIXED WITH ALLOGRAFT, Cancellous bone from anterior iliac crest
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Cairo University
Anterior Cruciate Ligament Reconstruction, Regional Anesthesia, Saphenous Nerve Block
Comparing Subsartorial Saphenous Nerve Blocks With and Without Dexamethasone for Anterior Cruciate Ligament Reconstruction
For patients undergoing Anterior Cruciate Ligament reconstruction surgery, the postoperative period can be a painful experience without adequate pain management.
- Trial name
- NCT01586806
- Testing
- Bupivacaine Only, Bupivacaine with 1 mg of Dexamethasone, Bupivacaine with 4 mg of Dexamethasone
- Where
- United States
- Volunteers
- 195 people
- Sponsor
- Hospital for Special Surgery, New York
Brachial Plexus Injury
Enhancing Functional Hand Recovery Through Nerve Reconstruction in Total Brachial Plexus Birth Injury
Interpreting the published outcomes of hand function in total BPBI is confounded by a lack of clear documentation regarding detailed surgical findings and management strategies.
- Trial name
- NCT06313658
- Testing
- Total brachial plexus exploration and reconstruction
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Assiut University
Anesthesia; Reaction
Adductor Canal Block Versus Femoral Nerve Block for Analgesia After Anterior Cruciate Ligament Reconstruction Arthroscopically
This study aims to compare continuous femoral nerve block with adductor canal block after anterior cruciate ligament reconstruction arthroscopically，especially in the effect on quadriceps strength; and to evaluate which regional…
- Trial name
- NCT02355093
- Testing
- adductor canal block (ACB), Femoral nerve block (FNB), ropivacaine
- Volunteers
- 40 people
- Sponsor
- Shanghai Jiao Tong University Affiliated Sixth People's Hospital
Mandible Fracture, Mandibular Reconstruction
Stryker's Surgeon iD Mandible Reconstruction Plates: A Retrospective Post Market Follow Up
A retrospective post market follow up to confirm safety and performance of Stryker's Surgeon iD Plates (SMRP) medical device. The study is performed to confirm the product's performance and safety by systematically collecting…
- Trial name
- SMRP (NCT07221916)
- Testing
- Mandibular Reconstruction
- Where
- 2 sites in United States, Germany
- Volunteers
- 70 people
- Sponsor
- Stryker Craniomaxillofacial
Musculoskeletal System
The Efficacy of Rehabilitation Exercise on the Non-operative Limb Following Anterior Cruciate Ligament Reconstruction
The purpose of this study is to evaluate the efficacy of a cross-education rehabilitation intervention following anterior cruciate ligament reconstruction on ameliorating the acute losses to function and performance.
- Trial name
- EFCOR (NCT02722876)
- Testing
- Contralateral Rehabilitation
- Where
- United Kingdom
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Robert Jones and Agnes Hunt Orthopaedic and District NHS Trust
Finger Tip Amputations
The Use of Composite Bone and Nail Bed Graft Combined With Cutaneous Flaps for Reconstruction of Finger Tip Amputations
Fingertip injuries are among the most common hand injuries regardless of age, as the fingertip is a prominent and frequently used part of the hand.
- Trial name
- NCT05961891
- Testing
- The Use of Composite Bone and Nail Bed Graft Combined With Cutaneous Flaps for Reconstruction of Finger Tip Amputations
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Sohag University
Breast Cancer
Lateral Thigh Perforator (LTP) Flap for Autologous Breast Reconstruction
The lateral thigh perforator (LTP) flap was previously introduced as an alternative flap for autologous breast reconstruction when the abdomen is not suitable as a donor site.
- Trial name
- NCT03106233
- Testing
- LTP flap
- Where
- Netherlands
- Volunteers
- 86 people
- Sponsor
- Maastricht University Medical Center
ACL Reconstruction, ACL Surgery
Post Operative Use of Neuromuscular Electrical Stimulation (NMES) Device for ACLR Patients
This study is being conducted to learn about how neuromuscular electrical stimulation (NMES) in addition to standard of care aids in the recovery of muscle strength in patients undergoing ACLR procedure.
- Conditions
- ACL Reconstruction, ACL Surgery, ACL Injury, Electrotherapy
- Trial name
- NCT07171346
- Testing
- Zynex NexWave Electrotherapy Device
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Kansas Medical Center
Aortic Valve Disease
Aortic Valve Leaflets Reconstruction (Ozaki Procedure) in Aortic Valve Diseases
Prospective Cohort Study aims at elaborating the outcomes of the Tricuspid Reconstruction of Aortic valve leaflets using autologous pericardium (Ozaki procedure) in the adult and paediatric patients.
- Trial name
- NCT04816851
- Testing
- OZAKI technique
- Where
- Egypt
- Volunteers
- 1 people
- Sponsor
- Assiut University
Alveolar Cleft
Metformin and Alveolar Cleft
Completed medical history will take for all patients. All patients' guardians were informed about the procedure, the possible postoperative complications, and requested to sign an informed consent that was translated into Arabic…
- Trial name
- NCT07536620
- Testing
- metformin group
- Volunteers
- 36 people
- Sponsor
- Fayoum University
Quadriceps Atrophy, ACL Reconstruction
Does Blood Flow Restriction Training Improve Quadriceps Function After Arthroscopic Knee Surgery?
The purpose of this study is to evaluate the effectiveness of physical therapy (PT) plus BFR training compared to PT alone (without BFR training) after ACL reconstruction in patients who require extended limited weight bearing…
- Trial name
- NCT03096366
- Testing
- Blood flow restriction, Physical therapy
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- The University of Texas Health Science Center, Houston