Clinical trials: Reconstructive Surgical Procedure
Bone Defects
Treatment of Complex Ridge Defects With Custom Meshes
Brief introduction: After tooth extraction, alveolar defects may hinder implant placement. Digital imaging and CAD/CAM advances allow creation of patient-specific titanium meshes for effective bone augmentation.
- Trial name
- NCT07268456
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people
- Sponsor
- TC Erciyes University
Aortic Arch Hypoplasia or Atresia
Modified Perfusion for Neonatal Aortic Arch Reconstruction
Even though the lower part of the body does receive some blood supply during Cardiopulmonary Bypass(CPB) surgery, it may not be enough.
- Trial name
- NCT00490256
- Testing
- Modified Selective Cerebral Perfusion
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Emory University
Anterior Cruciate Ligament Injury, Knee Injury
Anterior Cruciate Ligament (ACL) Tunnel Widening Comparing All-inside and Interference Screw Fixation Technique
The purpose of this study is to evaluate the incidence and degree of bone tunnel widening between two groups who have undergone anterior cruciate ligament reconstructive surgery.
- Conditions
- Anterior Cruciate Ligament Injury, Knee Injury, ACL Injury
- Trial name
- NCT02052856
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University of British Columbia
Reconstructed Jaws, Free Fibula Flaps
Assessment of the Stability of Immediately Loaded All-on-four Dental Implants in FFF Used for Reconstruction of the Jaws
The use of free vascularized fibula flaps for bony reconstruction has proved its success as a substitution for the resected bone and in some instances, the surrounding soft tissues The aim of this case series study is to evaluate…
- Conditions
- Reconstructed Jaws, Free Fibula Flaps, All on Four Technique
- Trial name
- NCT03950284
- Testing
- immediate loading with all on four technique in FFF
- Where
- Egypt
- Volunteers
- 10 people
- Sponsor
- Cairo University
Microtia, Outcome Assessment
Safety and Efficacy of Connecting the Residual Ear to the Cartilage Scaffold in First- vs. Second-Stage Surgery
Eligible patients will be admitted from the outpatient clinic to complete the relevant examinations after admission（Preoperative routine examination and chest CT）.
- Conditions
- Microtia, Outcome Assessment, RCT, Surgery Related Complications Rate
- Trial name
- NCT06763991
- Testing
- Two-stage connection, One-stage connection
- Where
- China
- Volunteers
- 78 people
- Sponsor
- Sichuan Provincial People's Hospital
Breast Reconstruction With Silicone Implants
McGhan Medical Silicone-Filled Breast Implant Adjunct Study
This study will collect 5 year data about any possible health problems associated with breast implants. This data will be used to help see if the implants are both safe and effective.
- Trial name
- NCT00581984
- Where
- United States
- Volunteers
- 1,016 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Knee Injuries
Non- vs Partial Controlled Weightbearing After Multiple Knee Ligament Reconstruction
This is a prospective randomized controlled trial with the purpose to determine if patients undergoing isolated posterior cruciate ligament (PCL) reconstruction, or isolated medial collateral ligament (MCL) reconstruction, or…
- Trial name
- NCT05073276
- Testing
- Physical Therapy
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Twin Cities Orthopedics
Rehabilitation, ACL Reconstruction
Neuromuscular Intervention Targeted to Mechanisms of ACL Load in Female Athletes
The overall goal of this project is to reduce risk of second anterior cruciate ligament (ACL) injury in vulnerable populations (active athletes between 14 = 24 years old) through the identification of relative injury risk groups…
- Trial name
- NCT03190889
- Testing
- HOME, TNMT
- Where
- 4 sites in United States
- Volunteers
- 150 people
- Sponsor
- Mayo Clinic
Heart Diseases
Evaluation of Left Ventricular Volumes by Real-Time 3-Dimensional Echocardiography
Quantitative measurements of left ventricular volume and ejection fraction are useful in the management of patients with heart disease.
- Trial name
- NCT00001740
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Finger Injuries
Dorsal Finger Reconstruction
objective of this study is To compare reversed cross finger flap with reversed island homo-digital flap in distal dorsal finger defect reconstruction regarding reliability \& functional and aesthetic outcomes .
- Trial name
- NCT04961879
- Testing
- Reversed Cross Finger Flap, reversed island homo-digital flap
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Sohag University
Head Neck Neoplasms
Recipient Vessels for Free Tissue Flaps in Advanced Oncologic Defects of the Midface and Scalp
The goal of this clinical trial is to compare the postoperative outcomes based on superficial temporal versus cervical recipient vessels for midface and scalp advanced oncologic defects using free tissue flap for reconstruction.
- Trial name
- NCT05749120
- Testing
- Recipient vessel selected for microanastomosis
- Where
- Brazil
- Volunteers
- 32 people
- Sponsor
- Instituto Nacional de Cancer, Brazil
Ear Cartilage, Platelets
Use of Platelet-enriched Plasma During Auricular Reconstruction
In this study investigators are trying to determine the benefits of using platelet enriched plasma during the second stage of auricular reconstruction. The intervention will be blinded to the surgeon and the surgical team.
- Conditions
- Ear Cartilage, Platelets, Microtia-Anotia
- Trial name
- NCT03215979
- Testing
- Platelet enriched plasma administration
- Where
- Mexico
- Volunteers
- 36 people
- Sponsor
- Hospital General Dr. Manuel Gea González
Anterior Cruciate Ligament Reconstruction
Prospective Evaluation of Silk Fibroin Incision Dressings in ACL Reconstruction
The purpose of this study is to compare the incidence of early postoperative skin complications including allergic contact dermatitis, blistering, and erythema between silk fibroin incision dressings and cyanoacrylate closure in…
- Trial name
- NCT07217613
- Testing
- silk fibroin-based incision dressing, cyanoacrylate-based closure system
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- NYU Langone Health
Atrophic Anterior Maxillary Ridges
Horizontal Ridge Reconstruction of Atrophic Anterior Maxillary Ridges Using Customized Xenograft Bone Shell With 1 :1 Mixture of Autogenous and Xenograft Bone Particulate
Using customized Xenograft bone shell with mixture of autogenous and xenograft particulate in modified cortical shell technique. by 3D printed model from The CT scans segmentation by special software
- Trial name
- NCT04075942
- Testing
- Atrophic Anterior Maxillary Ridges
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Manal Ahmed Hassan Ahmed
Anterior Cruciate Ligament Rupture
Improving Maximal Strength in the Initial Postoperative Phase After Anterior Cruciate Ligament Reconstruction Surgery: Randomized Controlled Trial of an App-Based Serious Gaming Approac
The investigators designed a prospective randomized trial to evaluate whether an app based active muscle training program (GenuSport) can improve the postoperative strength by starting rehabilitation immediately after primary…
- Trial name
- NCT04224376
- Testing
- App based Serious Gaming with the Genu Sport knee trainer
- Volunteers
- 26 people
- Sponsor
- Hannover Medical School
Lip Injury
The Reliability and Versatility of Facial Artery Perforator-Based Nasolabial Flaps in The Reconstruction of Lip Defects
Nasolabial flaps have limited mobility and may need two stages, mostly for intraoral defects .The facial artery perforator-based flap is the first true perforator flap in the face.
- Trial name
- NCT04974918
- Testing
- Facial Artery Perforator-Based Nasolabial Flaps in The Reconstruction of large Lip defects post traumatic or post tumor resection.
- Volunteers
- 20 people
- Sponsor
- Sohag University
Spinal Cord Injuries (SCI)
Epidural Electrical Stimulation in Spinal Cord Injury
The goal of this clinical trial is to evaluate the safety and effectiveness of Epidural Electrical Stimulation (EES) in motor and sensory function Reconstruction in chronic spinal cord injury (SCI) patients classified as ASIA…
- Trial name
- NCT07105878
- Testing
- Epidural Electrical Stimulation, Standard Rehabilitation Therapy, positron emission tomography-computed tomography (PET-CT)
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
ACL Tear
CT Evaluation of ACL Anatomical Reconstruction
Our research is to evaluate the position and length of femoral tunnel, and to examine whether knee stability and clinical functional outcomes are better while using two-portal or three-portal technique .
- Trial name
- NCT06575543
- Testing
- CT
- Where
- Egypt
- Volunteers
- 72 people
- Sponsor
- Assiut University
Congenital Cataracts
Effects of Visual Reconstruction on Brain Function and Structure in Children With Congenital Cataract
Children have considerable plasticity of the visual system during the formation and maturation of various visual functions at different ages. Congenital cataracts are the leading cause of treatable blindness in children.
- Trial name
- NCT05527925
- Testing
- MRI
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
ACL Reconstruction, Cognitive Function
Test of Return to Sport After ACL Reconstruction and Cognitive Task.
After reconstruction of the anterior cruciate ligament, the aim for the vast majority of sportspeople is to return to the field.
- Conditions
- ACL Reconstruction, Cognitive Function, Single Leg Hop Firm Surface, Testing Effect of Intervention
- Trial name
- AQQSHTATC (NCT06768957)
- Testing
- Single leg hop for distance, Single leg hop for distance plus cognitive task
- Where
- 4 sites in France
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Simon VALOT