Clinical trials: Reconstructive Surgical Procedure
Fixation of Double Barrel Vascularized Fibula
3D Titanium Miniplates Versus 3D Titanium Mesh Method of Fixation for Double Barrel Vascularized Fibular Graft
The double barrel fibula flap presents many advantages such as adequate, constant geometry, proper dimensions for implant placement, double periosteal and medullary blood supply allowing multiple osteotomies, correct contouring…
- Trial name
- NCT04704167
- Testing
- fixation of double barrel vascularised fibula
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Cairo University
Lymphatic Reconstruction
Objective Assessment of Outcomes Following Immediate Lymphatic Reconstruction / LYMPHA
Immediate lymphatic reconstruction (ILR) is a novel surgical approach performed at the time of initial lymph node dissection with the goal of preventing lymphedema.
- Trial name
- NCT06650592
- Testing
- All patients who were candidates for immediate lymphatic reconstruction (ILR)
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Reconstruction of Massive Bone Loss (Oncologic and Non-oncologic)
Prospective Evaluation of Adler Laboratory's Massive Prosthetic Implants in Oncological and Non-oncological Situations
Massive prostheses are the standard treatment for extensive bone loss, whether caused by cancer or other factors (complex fractures, multiple revisions, infections).
- Trial name
- IMPULSION (NCT07369778)
- Where
- France
- Volunteers
- 375 people
- Sponsor
- Nantes University Hospital
Right Ventricular Outflow Tract Absent, Congenital Heart Disease
New Designed ePTFE Valved Conduits for Surgical Reconstruction of Right-ventricular Outflow Tract
Valved conduits used for the reconstruction of right-ventricular outflow tract are applied in the surgical repair of complex congenital heart disease(CHD) such as pulmonary atresia(PA), truncus arteriosus, severe tetralogy of…
- Conditions
- Right Ventricular Outflow Tract Absent, Congenital Heart Disease, Pulmonary Valve Disorders
- Trial name
- NCT04152967
- Testing
- new-designed PTFE valved conduits, Bovine jugular vein valved conduits
- Where
- 3 sites in China
- Volunteers
- 200 people
- Sponsor
- Children's Hospital of Fudan University
Sellar Tumor, Endonasal Surgery
Efficacy and Safety Evaluation of Absorbable and Moldable Skull Base Support Plates in Extended Endoscopic Endonasal Transsphenoidal Surgery: A Prospective, Randomized, Controlled Study
Primary objective: To evaluate the effect of absorbable and moldable skull base support plates used in extended endoscopic endonasal transsphenoidal surgery on the incidence of cerebrospinal fluid (CSF) rhinorrhea within 1 month…
- Conditions
- Sellar Tumor, Endonasal Surgery, Csf Leakage
- Trial name
- EEEA-AMSBP (NCT07539792)
- Testing
- Absorbable and moldable skull base support plate
- Where
- 8 sites in China
- Volunteers
- 126 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Hand Injuries
Reconstruction of Hand Soft Tissue Defects
Evaluation of distally based posterior interosseous artery flap in reconstructing hand soft tissue defects that may result from trauma, extensive burns, tumor resection or congenital deformities.
- Trial name
- NCT05218252
- Testing
- Posterior interosseous artery flap
- Where
- Egypt
- Volunteers
- 15 people
- Sponsor
- Sohag University
Anterior Cruciate Ligament Reconstruction
Accelerated vs Non-Accelerated Rehabilitation After Anterior Cruciate Ligament Reconstruction: A Pilot Study
This study is comparing accelerated versus nonaccelerated rehabilitation following ACL reconstruction. Patients undergoing ACL reconstruction will be randomly allocated to one of the two rehabillitation pathways.
- Trial name
- AVON ACL (NCT03648944)
- Testing
- Accelerated Rehabillitation, Non-Accelerated Rehabillitation
- Where
- United Kingdom
- Volunteers
- 7 people
- Sponsor
- North Bristol NHS Trust
ACL Injury, ACL Reconstruction
Comparative Effectiveness of Blood Flow Restriction With or Without Total Motion Release in ACL Rehabilitation
The aim of this clinical trial is to compare the effectiveness of combined Blood Flow Restriction (BFR) and Total Motion Release (TMR) versus BFR alone in the restoration of muscular strength, balance and knee functionality in…
- Trial name
- BFR-TMR-ACL (NCT07589309)
- Testing
- Blood Flow Restriction, Total Motion Release
- Where
- Pakistan
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Green International University
Anterior Cruciate Ligament Tear
Bridge-Enhanced ACL Repair vs ACL Reconstruction
The goal of this trial is to compare the efficacy of the Bridge-Enhanced Anterior Cruciate Ligament Repair (BEAR™) technique with the current method of treatment for anterior cruciate ligament (ACL) injuries, ACL reconstruction.
- Trial name
- NCT02664545
- Testing
- BEAR Scaffold, Tendon Graft
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Miach Orthopaedics
Pilonidal Disease
Comparison Between Two Different Technique in Treatment of Chronic Pilonidal Disease
Comparison between limberg flap and Karydakis flap for treatment of pilonidal disease.
- Trial name
- PND (NCT01268969)
- Testing
- KARYDAKIS GROUP, Lamberg flap technique
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Mansoura University
Sensory Restoration of the Reconstructed Finger Pulps, Cold Intolerance of the Reconstructed Finger
Nerve Transfer for Finger Sensory Reconstruction With Dorsal Branch of the Digital Nerve
A proper digital nerve (PDN) defect causes partial or complete sensory loss of the finger pulp, which results in functional disability.The dorsal branch of the PDN can be transferred for reconstruction of such nerve defects.In…
- Conditions
- Sensory Restoration of the Reconstructed Finger Pulps, Cold Intolerance of the Reconstructed Finger, Pain of the Reconstructed Finger
- Trial name
- NCT01559337
- Testing
- Nerve transfer
- Where
- China
- Volunteers
- 17 people
- Sponsor
- The Second Hospital of Tangshan
ACL Reconstruction
Methylprednisolone Addition to Multimodal Pain Regimens After Anterior Cruciate Ligament Reconstruction
Patients who are being seen for ACL tears will be approached in the UAB Orthopedic Clinic. Included patients will be those aged 14-65 undergoing ACL Reconstruction.
- Trial name
- NCT07605923
- Testing
- Methyl Prednisolone (MP), Standard Post-Operative Pain Control, Surgeon's Standard ACL Postoperative Regimen
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- University of Alabama at Birmingham
Cruciate Ligament Rupture
Stability of the Knee Joint After Anterior Cruciate Ligament and Anterolateral Ligament Reconstruction
The objective of this randomised cohort study was to evaluate the knee rotational stability after the single-bundle ACL reconstruction (SB) with addition of the ALL reconstruction and to compare it with the double-bundle ACL…
- Trial name
- NCT02993679
- Testing
- reconstruction of the ACL and anterolateral ligament
- Volunteers
- 60 people
- Sponsor
- Hospital Znojmo
Patellar Dislocation, Recurrent, Patellar Dislocation
JUPITER 4.0 - Risk Factors for Failure of Isolated Medial Patellofemoral Ligament Reconstruction
The goal of this observational study is to learn about the outcomes of medial patellofemoral ligament (MPFL) reconstruction for the treatment of recurrent patellar instability.
- Conditions
- Patellar Dislocation, Recurrent, Patellar Dislocation, Patellar Instability, Patellofemoral Dislocation
- Trial name
- NCT06883396
- Testing
- Medial Patellofemoral Ligament (MPFL) Reconstruction
- Where
- 16 sites in United States
- Volunteers
- 850 people
- Sponsor
- Hospital for Special Surgery, New York
Narcotic Consumption, Pain
Motorized Continuous Cold Therapy Versus Standard Post-op Icing Protocol for Two Foot and Ankle Procedures
This study will compares differences in pain level, narcotic consumption, wound healing, patient satisfaction in patients randomized to the Iceman® cold pack therapy system (djOrtho, Inc) versus those who use ice.
- Conditions
- Narcotic Consumption, Pain, Wound Healing, Patient Satisfaction
- Trial name
- NCT00950183
- Testing
- Iceman® Cold Therapy unit (djOrtho), Ice
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- OrthoCarolina Research Institute, Inc.
Appendicitis
CT Dose Simulation Study for Appendicitis
The study will explore CT radiation dose as low as reasonably achievable in diagnosing acute appendicitis, by using of dose simulation technique and iterative reconstruction.
- Trial name
- NCT02556983
- Testing
- CT
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Seoul National University Bundang Hospital
Healthy, Tomography
Effect of Respiratory Motion on Positron Emission Tomography Imaging
This study will determine how breathing motions may affect positron emission tomography (PET) scans. It has been discovered that the quality of PET scans varies according to which part of the breathing cycle patients hold their…
- Conditions
- Healthy, Tomography, Emission Computed
- Trial name
- NCT00088361
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
ACL Injury, Knee Injuries
Association Between 4-Month Isokinetic Testing Measures and Second Knee Injuries After Primary Anterior Cruciate Ligament Reconstruction
Anterior cruciate ligament (ACL) is a frequent and disabling injury in athletes. Most of the time, ACL reconstruction (ACLR) is consider for regaining function and returning to preinjury sports while reducing the risk of…
- Conditions
- ACL Injury, Knee Injuries, Muscle Weakness
- Trial name
- PREDICT-ACLv2 (NCT05897970)
- Testing
- Return-to-sport (RTS) follow-up
- Where
- France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Caen
Anterior Cruciate Ligament
Evaluation of Outpatient Surgery in the Anterior Cruciate Ligament Reconstructions With Hamstring Hospital
Care in ambulatory surgery (CA) is growing in France, despite lagging behind other countries in North or US Europe. Arthroscopic knee surgery is a minimally invasive surgery eligible for CA.
- Trial name
- DIDTGENOU (NCT02895607)
- Testing
- Ambulatory care among eligible patients
- Where
- France
- Volunteers
- 9 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Inguinal Hernia
Desarda Repair for Inguinal Hernia in Adolescent Males
This retrospective single-centre case series evaluates the feasibility and clinical outcomes of selective open Desarda repair for inguinal hernia in adolescent males treated in a paediatric surgical department.
- Trial name
- NCT07870902
- Testing
- Open Desarda inguinal hernia repair
- Where
- Poland
- Volunteers
- 12 people
- Sponsor
- Medical University of Silesia