Clinical trials: Rectal Resection
Anastomotic Leakage in Colon Surgery
Predictive Value of Procalcitonin, CRP, Drain Fluid Culture, Il-6 and Tnf-α in Anastomotic Leakage
Evaluating predictive value of serum procalcitonin, C-Reactive Protein, drain IL-6 and TNF-alpha for anastomotic leakage in post-operative period.
- Trial name
- NCT02361918
- Testing
- Colon surgery
- Volunteers
- 50 people
- Sponsor
- Istanbul University
Slow Transit, Constipation
Resection Location of Rectum in Laparoscopic Surgery for Slow Transit Constipation
Study the recurrence rate of constipation after laparoscopic total colectomy with high resection or low resection of rectum
- Trial name
- NCT04525248
- Testing
- Laparoscopic total colectomy + low resection of rectum, Laparoscopic total colectomy + High resection of rectum
- Volunteers
- 78 people
- Sponsor
- Shanghai Minimally Invasive Surgery Center
Carcinoma
A Non Interventional Study With Oxaliplatin Onkovis (Oxaliplatin) Utilized for the Treatment of Cancer
The main purpose of this observational study with Oxaliplatin onkovis is to determine the number of treatment cycles and the quantity of Oxaliplatin onkovis needed for this purpose under the special circumstances of ambulant…
- Trial name
- NCT01942200
- Where
- 3 sites in Germany
- Volunteers
- 383 people
- Sponsor
- Onkovis GmbH
Surgery, Colorectal Neoplasm
Predictive Factors of Conversion in Laparoscopic Colorectal Cancer Resection
Background Laparoscopic resection is the treatment of choice for colorectal cancer. Rates of conversion to open surgery range between 7% and 30% and controversy exists as to the effect of this on oncologic outcomes.
- Conditions
- Surgery, Colorectal Neoplasm, Laparoscopy
- Trial name
- NCT04589975
- Testing
- laparoscopic surgery
- Volunteers
- 829 people
- Sponsor
- Clinica Universidad de Navarra, Universidad de Navarra
Low Rectal Cancer
Outcomes of TAMIS-Total Mesorectal Excision Versus Transanal Loco-regional Excision for T2 Low Rectal Cancer
Cases with stage T2 N0 low rectal cancer will undergo either Transanal minimally invasive total mesorectal excision or transanal minimally invasive locoregional resection.
- Trial name
- TAMIS (NCT02488577)
- Testing
- Transanal minimally invasive total mesorectal excision, transanal minimally invasive locoregional resection
- Volunteers
- 50 people
- Sponsor
- Osama Mohammad Ali ElDamshety
Intestinal Anastomotic Leak
Risk Factors for Anatomic Leakage in Advanced Ovarian Cancer Surgery
Cytoreductive surgery is currently the main treatment for advanced epithelial ovarian cancer (AEOC), and the complete disease removal (RT=0) or the achievement of an optimal residual disease (RT < 1 cm) remain the factors with…
- Trial name
- NCT04604964
- Testing
- Evaluation of anastomotic leakage occurrence
- Where
- Italy
- Volunteers
- 515 people
- Sponsor
- Catholic University of the Sacred Heart
Colorectal Cancer
A Study of Avastin (Bevacizumab) in Combination With XELOX in Patients With Metastatic Colorectal Cancer
This single arm study will assess the resection rate of liver metastasis, time to disease progression, and safety of neoadjuvant treatment with Avastin in combination with oxaliplatin and capecitabine (XELOX) in patients with…
- Trial name
- NCT00700570
- Testing
- bevacizumab [Avastin], capecitabine [Xeloda], oxaliplatin
- Where
- 6 sites in Taiwan
- Volunteers
- 45 people
- Sponsor
- Hoffmann-La Roche
Neoplasm of Rectum, Surgery--Complications
Validation of Low Anterior Resection Syndrome Score in Korean Version
In contemporary era of rectal cancer treatment, development of surgical technique and tool, adaptation of chemoradiation therapy, as well as multidisciplinary approach have led increased survival as well as rate of sphincter…
- Conditions
- Neoplasm of Rectum, Surgery--Complications, Surgery
- Trial name
- NCT03211715
- Testing
- questionnaire
- Volunteers
- 300 people
- Sponsor
- Saint Vincent's Hospital, Korea
Rectal Cancer
Intraoperative Angiography Using ICG in Rectal Cancer Patients to Prevent Anastamotic Leak After Laparoscopic Anterior Resection of the Rectum
The study enrols patients with operative rectal cancer qualified for laparoscopic anterior resection. Patients are given first dose of indocyanine green iv intraoperatively (ICG) before choosing the appropriate site of the…
- Trial name
- NCT05263336
- Testing
- Verdye Green
- Where
- Poland
- Volunteers
- 180 people
- Sponsor
- Jagiellonian University
Colorectal Cancer, Colorectal Adenocarcinoma
Analysis of Histopathological Factors Predictive of Lymph Node Involvement and Management Practices in pT1 Colorectal Cancers Treated by Primary Endoscopic Resection
Colorectal cancers (CRC) extending beyond the muscularis mucosae and invading the submucosa without extending beyond it are classified as pT1.
- Trial name
- PROMOT1 (NCT06339346)
- Where
- France
- Volunteers
- 400 people
- Sponsor
- University Hospital, Brest
Colorectal Cancer
Minimally Invasive Simultaneous Colorectal and Liver Surgery
Up to 25% of newly diagnosed patients with colorectal cancer (CRC) have liver metastases (LM). Simultaneous colorectal and hepatic resection has been proven to be a safe and effective approach in dealing with metastatic…
- Trial name
- NCT03551470
- Testing
- Robotic one-stage colorectal and liver resection
- Where
- Italy
- Volunteers
- 22 people
- Sponsor
- Azienda Ospedaliera San Giovanni Battista
Hemorrhoid Pain, Hemorrhoids
Topical Analgesia Post-Haemorrhoidectomy
Symptomatic haemorrhoids, or piles, have significant effects on quality of life. The treatment for advanced disease is surgical excision (haemorrhoidectomy) which is extremely effective.
- Trial name
- NCT04276298
- Testing
- Metronidazole cream, Metronidazole and Diltiazem cream, Metronidazole and Lidocaine cream
- Where
- New Zealand
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- University of Auckland, New Zealand
Complications of Surgical Procedures, Surgical Site Infection
Quick Skin Sealant in Closure of Surgical Wound After Laparoscopic Surgery
The purpose of this study is to evaluate the short-term effect of sealant-assisted skin closure in prevention of surgical site infection after laparoscopic surgery.
- Conditions
- Complications of Surgical Procedures, Surgical Site Infection, Gastric Cancer, Colorectal Cancer
- Trial name
- NCT02426762
- Testing
- Laparoscopic surgery, Skin sealant
- Where
- China
- Volunteers
- 100 people
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Rectal Cancer
Comparison of Low and High Ligation in the Rectal Cancer
The purpose of this study is to evaluate the defecatory function when nerve fibers around the inferior mesenteric artery(IMA) and left colic artery(LCA) are preserved(so called low ligation ) or not(high ligation) in the…
- Trial name
- NCT00701012
- Testing
- preservation of nerve fibers around IMA, resection of nerve fibers around IMA
- Where
- Japan
- Volunteers
- 100 people
- Sponsor
- Wakayama Medical University
Rectal Cancer, Rectal Adenocarcinoma
Factors Predicting Recurrence in Rectal Cancer After Surgery
Colorectal cancer is one of the most frequently diagnosed cancers and a major cause of cancer deaths worldwide. Recurrence after curative surgery is one of the major factors affecting the long-term survival and its frequency is…
- Trial name
- NCT03899870
- Testing
- Rectal resection, Neoadjuvant therapy, Adjuvant therapy
- Volunteers
- 188 people
- Sponsor
- ammar houssem
Quality of Life, Fecal Incontinence
J-Pouch vs Side-to-End Anastomosis After Hand-Assisted Laparoscopic Low Anterior Resection for Rectal Cancer
Current study aims to analyze the outcomes of j-pouch and side-to-end anastomosis in rectal cancer patients treated with laparoscopic hand-assisted low anterior resection
- Conditions
- Quality of Life, Fecal Incontinence, Postoperative Complications
- Trial name
- NCT02627729
- Testing
- Linear cutter-Circular stapler, Circular stapler
- Volunteers
- 74 people
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Rectal Neoplasms
Defunctioning Cannula Ileostomy After Lower Anterior Resection of Rectal Cancer
Most surgeons suggest the use of fecal diverting to address the high morbidity and mortality associated with anastomotic leakage (AL) in patients with high risk factors on AL who are undergoing anterior resections.
- Trial name
- NCT01980238
- Testing
- cannula ileostomy, loop ileostomy, LAR
- Where
- China
- Volunteers
- 300 people
- Sponsor
- First Affiliated Hospital of Zhejiang University
Rectal Neoplasms, Low Anterior Resection
Use of One Kind of Controllable Tube Ileostomy in the Low Rectal Cancer
Most surgeons suggest the use of fecal diverting to address the high morbidity and mortality associated with anastomotic leakage (AL) in patients with high risk factors on AL who are undergoing low anterior resections(LAR).
- Trial name
- CTI (NCT02012023)
- Testing
- Low anterior resection, tube ileostomy, loop ileostomy
- Where
- China
- Volunteers
- 80 people
- Sponsor
- First Affiliated Hospital of Zhejiang University
Colorectal Neoplasms, Gastric Neoplasms
Obtaining Solid Tumor Tissue From People Having Biopsy or Surgery for Certain Types of Cancer
Background: Recent advances in cancer research have led to new therapies to treat the disease. It is important to continue these advances and discover new ones. To do that, researchers need tissue samples from solid tumors.
- Conditions
- Colorectal Neoplasms, Gastric Neoplasms, Cholangiocarcinoma, Bile Duct Cancer
- Trial name
- NCT01915225
- Where
- United States
- Volunteers
- 1,800 people
- Sponsor
- National Cancer Institute (NCI)
Rectal Cancer
Introduction and Influence of Total Mesorectal Excision (TME) in the Treatment of Rectal Cancer
Total mesorectal excision (TME) is a rather new operation technique in the treatment of rectal cancer. It is known to reduce the rate of local recurrences. However, the influence on long-term survival is unclear.
- Trial name
- NCT00910143
- Testing
- conventional rectal surgery, total mesorectal excision
- Where
- Switzerland
- Volunteers
- 194 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern