Clinical trials: Recurrence
Preterm Labor
Oral Progestogen Supplementation in the Prevention of Recurrent Uterine Contraction in Preterm Labor
The purpose of this study is to evaluate the effect of oral progesterone supplementation in preterm labor on the prevention of recurrent uterine contraction and prolonging pregnancy period, and its side effect.
- Trial name
- NCT02262481
- Testing
- dydrogesterone
- Where
- Thailand
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Clostridium Difficile
Fresh Versus Frozen Stool for Fecal Transplant in Children
The primary goal of this study will be to assess whether stool collected and frozen from anonymous screened unrelated donors can be as effective as stool freshly collected from recipient's parents when used in Fecal Microbial…
- Trial name
- NCT02423967
- Testing
- Transplant uses frozen anonymous stool, Transplant uses fresh familial stool
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Mayo Clinic
Acute Asthma
Emergency Department (ED)-Directed Interventions to Improve Asthma Outcomes
The purpose of this study is to determine if evidence-based guidance on follow-up care and self-management provided to PCPs and patients, respectively, reduces relapses within 90 days for acute asthma (primary outcome).
- Trial name
- NCT01079000
- Testing
- Opinion Leader letter, Involvement of a care manager, Usual care
- Where
- 2 sites in Canada
- Volunteers
- 367 people
- Sponsor
- University of Alberta
Recurrent Wilms Tumor and Other Childhood Kidney Tumors, Stage III Wilms Tumor
Studying Biomarkers in Urine Samples From Younger Patients With Wilms Tumor
This research study is looking at biomarkers in urine samples from patients with Wilms tumor. Studying samples of urine from patients with cancer in the laboratory may help doctors identify and learn more about biomarkers related…
- Trial name
- NCT01614808
- Testing
- laboratory biomarker analysis
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Children's Oncology Group
Acute Ischemic Stroke, Active Cancer
Acute Ischemic Stroke in Patients With Active Cancer
The goal of this multicenter prospective observational study, conducted at 24 hospitals in Japan, is to learn about recurrent ischemic stroke in people with active cancer who develop acute ischemic stroke.
- Trial name
- CAT-AIS (NCT07819526)
- Where
- Japan
- Volunteers
- 500 people
- Sponsor
- Osaka University
Head and Neck Cancer
Study of Blood and Tissue Samples From Patients With Larynx Cancer, Pharynx Cancer, or Oral Cavity Cancer
RATIONALE: Studying samples of blood and tumor tissue from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer.
- Trial name
- CARIO (NCT00963326)
- Testing
- laboratory biomarker analysis
- Where
- 9 sites in France
- Volunteers
- 30 people
- Sponsor
- Centre Oscar Lambret
Kidney Cancer
Monoclonal Antibody Therapy in Treating Patients With Metastatic Renal Cell Cancer
RATIONALE: Monoclonal antibodies can locate tumor cells and either kill them or deliver tumor-killing substances to them without harming normal cells.
- Trial name
- NCT00057889
- Testing
- ipilimumab
- Where
- United States
- Sponsor
- National Institutes of Health Clinical Center (CC)
Colorectal Cancer, Metastatic Cancer
Intravenous Compared With Intrahepatic Chemotherapy in Treating Patients With Colorectal Cancer Metastatic to the Liver
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells.
- Trial name
- NCT00002692
- Testing
- fluorouracil, isolated perfusion, leucovorin calcium
- Where
- United Kingdom
- Volunteers
- 312 people
- Sponsor
- Medical Research Council
Borrelia Recurrentis Infection
Study of the Clinical, Microbiological and Epidemiological Characteristics of Recurrent Imported Borreliosis Confirmed by the CNR Borrelia
Recurrent borreliosis (RB) is a bacterial infection transmitted by ticks or lice. These infections occur in both temperate and tropical regions, but are rare in Australia and Antarctica.
- Trial name
- BORRECUR (NCT07335965)
- Where
- France
- Volunteers
- 25 people
- Sponsor
- University Hospital, Strasbourg, France
Cervical Adenocarcinoma, Cervical Adenosquamous Carcinoma
Capecitabine in Treating Patients With Persistent or Recurrent Cervical Cancer
Phase II trial to study the effectiveness of capecitabine in treating patients who have persistent or recurrent cervical cancer.
- Conditions
- Cervical Adenocarcinoma, Cervical Adenosquamous Carcinoma, Recurrent Cervical Carcinoma
- Trial name
- NCT00039442
- Testing
- Capecitabine, Laboratory Biomarker Analysis
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Gynecologic Oncology Group
Unspecified Childhood Solid Tumor, Protocol Specific
Thalidomide and Cyclophosphamide in Treating Children With Recurrent or Refractory Childhood Cancers
RATIONALE: Thalidomide may kill tumor cells by stopping the growth of new blood vessels to the tumor. Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.
- Trial name
- NCT00003754
- Testing
- cyclophosphamide, thalidomide
- Where
- United States
- Sponsor
- Memorial Sloan Kettering Cancer Center
Osteosarcoma, Osteosarcoma in Children
SARC038: Phase 2 Study of Regorafenib and Nivolumab in Osteosarcoma
A phase 2 study of regorafenib in combination with nivolumab in patients with refractory or recurrent osteosarcoma.
- Conditions
- Osteosarcoma, Osteosarcoma in Children, Osteosarcoma Recurrent, Osteosarcoma Metastatic
- Trial name
- NCT04803877
- Testing
- Regorafenib 40 MG, Regorafenib 20MG, Nivolumab
- Where
- 8 sites in United States
- Volunteers
- 48 people
- Sponsor
- Sarcoma Alliance for Research through Collaboration
Anaplastic Large Cell Lymphoma, Vinorelbine
Vinorelbine for Recurrent ALCL-2017
The purpose of this study is to assess the efficiency and safety of vinorelbine in the treatment of relapsed / advanced ALCL in children and adolescents.
- Trial name
- NCT03443128
- Testing
- Vinorelbine
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Children's Cancer Group, China
Breast Cancer
Diet and Exercise or Normal Care in Overweight or Obese Women Who Have Undergone Treatment for Stage I, Stage II, or Stage III Breast Cancer
RATIONALE: Studying diet and exercise interventions in overweight and obese patients with breast cancer may help doctors learn more about how to help patients lose weight and change their body composition.
- Trial name
- NCT00689975
- Testing
- behavioral dietary intervention, exercise intervention, counseling intervention
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- Sheffield Hallam University
Recurrent Acute Otitis Media, Acute Otitis Media
Efficacy of the EarPopper Device in Children With Recurrent Otitis Media
This is a randomized controlled clinical trial evaluating the efficacy of the EarPopper device (EP) in the reduction of episodes of acute otitis media (AOM) in children with recurrent otitis media.
- Trial name
- NCT03534219
- Testing
- EarPopper
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Northwell Health
Recurrent Renal Cell Cancer, Stage IV Renal Cell Cancer
SU5416 in Treating Patients With Metastatic Kidney Cancer That Has Not Responded to Previous Treatment
Phase II trial to study the effectiveness of SU5416 in treating patients who have metastatic kidney cancer that has not responded to previous therapy with interleukin-2.
- Trial name
- NCT00009919
- Testing
- semaxanib
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- National Cancer Institute (NCI)
Chronic Otitis Infections in pédiatric Patients
Efficacy of KNT® (KINETUBE) in Recurrent Chronic Otitis Media in Children
Otitis media are the consequence of bacterial infection. They are characterized by middle ear inflammations with a collection of fluid behind the eardrum.
- Trial name
- KINETUBE (NCT02038400)
- Testing
- KINETUBE medical Device, insertion of tympanic ventilation tubes (tympanostomy)
- Where
- France
- Volunteers
- 140 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Hemophilia, Chronic Synovitis
Intra-Articular Bevacizumab for Preventing Recurrent Hemarthrosis in Hemophilia With Chronic Synovitis
Hemophilia is an inherited bleeding disorder characterized by deficiency of clotting factors, leading to increased bleeding tendencies.
- Trial name
- NCT07187661
- Testing
- Intra-articular Bevacizumab
- Where
- 2 sites in Pakistan
- Volunteers
- 18 people
- Sponsor
- Khyber Medical University Peshawar
Recurrent World Health Organization (WHO) Grade II Glioma, Low-grade Glioma
Trametinib and Everolimus for Treatment of Pediatric and Young Adult Patients With Recurrent Gliomas (PNOC021)
This phase I trial studies the side effects and best dose of trametinib and everolimus in treating pediatric and young adult patients with gliomas that have come back (recurrent).
- Conditions
- Recurrent World Health Organization (WHO) Grade II Glioma, Low-grade Glioma, High-Grade Glioma (HGG)
- Trial name
- NCT04485559
- Testing
- Everolimus, Trametinib
- Where
- 17 sites in United States
- Volunteers
- 50 people
- Sponsor
- University of California, San Francisco
Lumbar Pain Syndrome
Evaluation and Timing in an ERAS-like Structured Rehabilitation Program After Lumbar Spine Surgery
The goal of this clinical trial is to investigate the safety of early inpatient rehabilitation after lumbar spine surgery. Participants are assigned to therapy groups C (low) - A (high) intensity and receive standardized…
- Trial name
- NCT05937997
- Testing
- high intensity physiotherapy, moderate intensity physiotherapy, low intensity physiotherapy
- Where
- Germany
- Volunteers
- 245 people
- Sponsor
- Median