Clinical trials: Recurrent Pancreatitis
Pancreatic Exocrine Insufficiency
The Development of a Metabolomic Test to Diagnose and Quantify Pancreatic Exocrine Insufficiency (The DETECTION Study)
DETECTION. The development of a metabolomic test to diagnose and quantify pancreatic exocrine insufficiency.
- Trial name
- DETECTION (NCT05980221)
- Testing
- Metabolomics, 13C MTGT
- Where
- United Kingdom
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University Hospital Birmingham NHS Foundation Trust
Chronic Pancreatitis
Feasibility Study of a Mobile Health App for Symptom Monitoring in People With Chronic Pancreatitis
Patients with chronic pancreatitis suffer from constant debilitating symptoms. They have complex needs and require specialist, multi-disciplinary care.
- Trial name
- SmartCP (NCT05899335)
- Testing
- SmartCP (mobile phone app)
- Where
- Ireland
- Volunteers
- 30 people
- Sponsor
- University of Dublin, Trinity College
Healthy Volunteers
MRCP: A Reliable, Non Invasive Method for Staging Chronic Pancreatitis in Pediatrics
The goal of this research study is to learn more about the pancreas. The investigators want to use Magnetic Resonance Cholangiopancreatography (MRCP) to learn more about the size of a normal pancreas.
- Trial name
- NCT02869893
- Testing
- Secretin
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Chronic Pancreatitis, Genetic Mutation
An Observational Study on the Natural Course of Chronic Pancreatitis
To explore the impact on genetic and environmental factors for clinical manifestation, and the progression of chronic pancreatitis, including development of pancreatic insufficiency and other complications.
- Conditions
- Chronic Pancreatitis, Genetic Mutation, Smoking, Tobacco, Drinking, Alcohol
- Trial name
- NCT04574297
- Testing
- smoking and alcohol assumption, genetic sequencing
- Volunteers
- 798 people
- Sponsor
- Changhai Hospital
Inflammatory Bowel Disease, Ulcerative Colitis
Efficacy of Energy Therapy in the Management of Chronic Pain Medical Condition in Children and Adolescents.
Paediatric and adolescent patients with chronic pain associated with their medical condition will be invited to participate in this study.
- Conditions
- Inflammatory Bowel Disease, Ulcerative Colitis, Crohn Disease, Chronic Pancreatitis
- Trial name
- ET&CP (NCT05394272)
- Testing
- Energy Therapy - Pranic Healing
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- King's College Hospital NHS Trust
Chronic Pancreatitis, Idiopathic Chronic Pancreatitis
Classification and Comparison of Early-onset and Late-onset Idiopathic Chronic Pancreatitis
Classification of early-onset idiopathic chronic pancreatitis (EOICP) and late-onset idiopathic chronic pancreatitis (LOICP) was proposed based on bimodal distribution of age at onset of idiopathic chronic pancreatitis (ICP).
- Trial name
- NCT03953937
- Where
- China
- Volunteers
- 1,633 people
- Sponsor
- Changhai Hospital
Biliary Stricture, Chronic Pancreatitis
Endoscopic Treatment of Biliary Stricture Caused by Chronic Pancreatitis
Benign biliary strictures can be endoscopically treated with plastic or self-expandable metal stents (SEMS). The purpose of the prospective randomized study is to compare the safety and feasibility of covered SEMS with multiple…
- Trial name
- NCT01085747
- Where
- Finland
- Volunteers
- 60 people
- Sponsor
- Helsinki University Central Hospital
Acute Pancreatitis Due to Gallstones, Acute Pancreatitis
PrEveNtion of Biliary Events After Acute Pancreatitis in NonSUrgicaL PAtients: PENINSULA Trial
Acute pancreatitis (AP) is a common condition and its main etiology is biliary. Cholecystectomy is the standard preventive treatment for recurrence of AP after admission.
- Trial name
- PENINSULA (NCT06409741)
- Testing
- Biliary sphincterotomy
- Where
- 5 sites in Spain
- Volunteers
- 126 people
- Sponsor
- Hospital General Universitario de Alicante
Chronic Pancreatitis
Ivacaftor Impact in an Adolescent Without a Cystic Fibrosis-Associated CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) Mutation for Chronic Pancreatitis: Single-Patient Study Tracking Flare Frequency and Health Data Compared to Historical Records.
The goal of this observational study is to learn about the long-term effects of Ivacaftor in an adolescent without a cystic fibrosis-associated CFTR mutation who is taking Ivacaftor to treat chronic pancreatitis.
- Trial name
- IMPACT (NCT07022327)
- Testing
- Ivacaftor 150 MG (milligrams)
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Mission: Cure
Chronic Pancreatitis, Acute Pancreatitis
Relationship of CP and AP
The present study aimed to determine the prevalence of AP attacks before the diagnosis of CP and further identified the potential associated factors for AP episodes.
- Trial name
- NCT04670705
- Testing
- patients' characteristics
- Volunteers
- 1,022 people
- Sponsor
- Changhai Hospital
Chronic Pancreatitis, Pancreatic Exocrine Insufficiency
Establishment and Clinical Application of Pancreatic Endocrine and Exocrine Function Tests
The goal of this observational study is to improve the epidemiological data of pancreatic exocrine insufficiency in China, determine the FE-1 cut-off value for the classification of PEI, and explore the characteristic differences…
- Conditions
- Chronic Pancreatitis, Pancreatic Exocrine Insufficiency, Diabetes Mellitus, Community Populations
- Trial name
- NCT06006312
- Testing
- fecal elastase-1 test, 72-hour fecal fat quantification, blood sample test
- Where
- China
- Volunteers
- 2,400 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Pancreatitis
EUROPAC-2 - Pain Treatment of Hereditary and Idiopathic Pancreatitis
This is a multi-centre randomised phase III, double blind, placebo controlled, parallel group, outpatient study in patients diagnosed with hereditary pancreatitis and idiopathic chronic pancreatitis.
- Trial name
- NCT00142233
- Testing
- ANTOX (vers.)1.2, Magnesium
- Volunteers
- 295 people
- Sponsor
- University Medicine Greifswald
Chronic Pancreatitis, Risk Factors
Risk Factors for Post-ESWL and Post-ERCP Pancreatitis
The study aimed to identify risk factors for post-ERCP pancreatitis(PEP) after ESWL, and the relationship between the occurrence of post-ESWL pancreatitis and PEP.
- Conditions
- Chronic Pancreatitis, Risk Factors, ERCP, ESWL
- Trial name
- NCT04619511
- Volunteers
- 714 people
- Sponsor
- Changhai Hospital
Pancreatitis, Chronic, Pancreatitis, Acute
Pediatric Longitudinal Cohort Study of Chronic Pancreatitis
The investigators will enroll a total of 628 patients under 18 years of age with ARP or CP. Included in the total are the 357patients in the INSPPIRE 1 database who are planned to be reenrolled under this protocol over the next 4…
- Trial name
- INSPPIRE 2 (NCT03672422)
- Testing
- Blood sample, Patient questionnaires, Saliva sample
- Where
- 22 sites in United States, Australia and 2 more
- Volunteers
- 623 people
- Sponsor
- Aliye Uc
Chronic Pancreatitis, Exocrine Pancreas Carcinoma
Biospecimen Collection to Identify Gene Mutations for High Risk Pancreatic Cancer in Pediatric Patients, INSPPIRE 2 Study
This clinical trial collects blood, saliva, urine, or stool samples to help identify possible genetic mutations that may increase a person's chance at developing pancreatic cancer.
- Conditions
- Chronic Pancreatitis, Exocrine Pancreas Carcinoma, Recurrent Acute Pancreatitis
- Trial name
- NCT06651580
- Testing
- Biospecimen Collection, Quality-of-Life Assessment, Questionnaire Administration
- Where
- 26 sites in United States, Australia and 2 more
- Volunteers
- 1,600 people
- Sponsor
- M.D. Anderson Cancer Center
Chronic Pancreatitis, Complication
The Natural History of Chronic Pancreatitis
Chronic pancreatitis (CP) is a disease characterized by inflammation and their replacement by fibrotic tissue. The destruction of pancreatic function and structure are the main complications.
- Conditions
- Chronic Pancreatitis, Complication, Risk Factors
- Trial name
- NCT03324698
- Where
- China
- Volunteers
- 4,000 people
- Sponsor
- Changhai Hospital
Chronic Pancreatitis
Endoscopic Versus Surgical Treatment of Chronic Pancreatitis
Chronic pancreatitis is a progressive inflammatory disease of the pancreas characterized by destruction of pancreatic parenchyma and subsequent fibrosis.
- Trial name
- NCT01520675
- Testing
- surgery, Endoscopic therapy
- Where
- India
- Volunteers
- 50 people
- Sponsor
- All India Institute of Medical Sciences
Chronic Pancreatitis, Genetic Mutation
Genetic Factors and CP Pregnancy Outcomes
To explore the impact of chronic pancreatitis (CP) susceptibility genes on pregnancy outcomes.
- Conditions
- Chronic Pancreatitis, Genetic Mutation, Pregnancy Related
- Trial name
- NCT06055595
- Testing
- genetic sequencing
- Where
- China
- Volunteers
- 160 people
- Sponsor
- Changhai Hospital
Chronic Pancreatitis, Inflammatory Bowel Diseases
Genomic Resources for Enhancing Available Therapies (GREAT1.0) Study
This is a prospective, descriptive, observational research study designed to observe and document the clinical practice by domain experts, and how the knowledge of new findings that are published in the medical literature affect…
- Conditions
- Chronic Pancreatitis, Inflammatory Bowel Diseases, Hepatitis, NASH - Nonalcoholic Steatohepatitis
- Trial name
- GREAT1 (NCT04306939)
- Testing
- venipuncture, Questionnaires, Additional Sample Collections
- Where
- United States
- Volunteers
- 120,000 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Chronic Pancreatitis, Pancreatic Neoplasm
Prediction Model of Pancreatic Neoplasms in CP Patients With Focal Pancreatic Lesions
This study aims to develop XGBoost machine learning model to predict pancreatic neoplasms in CP patients with focal pancreatic lesions.
- Conditions
- Chronic Pancreatitis, Pancreatic Neoplasm, Machine Learning
- Trial name
- NCT07045181
- Testing
- XGBoost machine learning
- Where
- China
- Volunteers
- 113 people
- Sponsor
- Changhai Hospital