Clinical trials: Refractive Disorders
Myopia
Examination of Myopia Progression and Soft Bifocal Contact Lens Myopia Control
This project intends to provide important, previously unmet answers regarding biological associations with myopia (nearsightedness) progression in order to improve the ability to predict patients who are most likely to benefit…
- Trial name
- BLINK2 (NCT04080128)
- Testing
- Contact lenses
- Where
- 2 sites in United States
- Volunteers
- 248 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Macula Hole, Retinal Detachment
Amniotic Membrane for Recurrent Macular Hole
Macular hole surgery were tried by different surgeons using many techniques with different successes but still there were many recurrences.
- Conditions
- Macula Hole, Retinal Detachment, Myopic Macular Degeneration
- Trial name
- NCT03528122
- Testing
- Recurrent opened macular hole
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Minia University
Myopia
Control of Myopia in Young Children Using H.O.P.E. Lenses Combined With 0.02% Atropine Eye Drops
A multicenter, prospective, intervention study on the control of myopia in young children using high-order phase element array microstructure lenses (H.O.P.E.) in combination with low-concentration atropine eye drops (0.02%)
- Trial name
- NCT07846787
- Testing
- High-order Phase Element Array Microstructure Design Lens (H.O.P.E.), 0.02% Atropine Sulfate Eye Drops
- Where
- China
- Volunteers
- 264 people
- Sponsor
- Ruihua Wei
Myopia
Family Myopia Study
This study will try to identify the gene or genes responsible for myopia (nearsightedness) and to examine the relationship between myopia and near work.
- Trial name
- NCT00341549
- Where
- United States
- Volunteers
- 7,477 people
- Sponsor
- National Human Genome Research Institute (NHGRI)
Myopia
A Clinical Trial to Evaluate the Efficacy and Safety of Defocusing Lenses in Delaying Myopia Progression
The objective of this clinical trial was to evaluate the efficacy and safety of defocusing lenses for delaying myopia progression in children and adolescents.
- Trial name
- NCT06411717
- Testing
- Microstructure lens A, Microstructure lens B, Control group
- Where
- China
- Volunteers
- 156 people
- Sponsor
- Suzhou Care-Real Medical Technology Co., Ltd.
Myopia
Short-term Clinical Performance of Multifocal Soft Contact Lens
The study is aimed to observe the short-term clinical performance of MiSight™ multifocal soft contact lens compared with Proclear™ 1day, including objective examination, subjective acceptability of wearers, and doctors'…
- Trial name
- NCT05273606
- Testing
- MiSight mutifocal soft contact lens, Proclear 1 Day soft contact lens
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Myopia, Children
Atropine 0.01% Eyedrops for Evolutive Myopia Treatment in Children
Prevalence of myopia and its complications has been increasing over the past decades, especially among children and adolescents.
- Trial name
- NCT04252989
- Testing
- data collection
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Myopia
The Collaborative Longitudinal Evaluation of Ethnicity and Refractive Error (CLEERE) Study
To compare and contrast normal eye growth, ocular component development, and refractive error development in Hispanic, African-American, and Asian schoolchildren with what happens in Caucasian children from the Orinda…
- Trial name
- NCT00000169
- Where
- 3 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Eye Institute (NEI)
Cataract, Refractive Errors
Comparison of Intraocular Lens Power Calculation Methods After Corneal Laser Refractive Surgery in Axial and Refractive Ammertropia
The study aims at determining the best biometry calculation formula to be used in IOL calculation of cataract patients how previously underwent laser refractive correction surgery
- Trial name
- NCT01979172
- Where
- Egypt
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- The National Eye Hospital, Cairo, Egypt
Myopia
Comparison of Verofilcon A Daily Disposable Lenses to Somofilcon A Daily Disposable Lenses
The objective of the study is to evaluate and compare the performance of verofilcon A to somofilcon A when worn on a daily disposable modality over a period of approximately one week each.
- Trial name
- NCT04305912
- Testing
- somofilcon A, verofilcon A
- Where
- Canada
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Myopia
Orthokeratology and 0.01% Atropine Sequential Treatment for Myopia Control
The purpose of this multicenter randomized clinical trial is to evaluate the myopia control effect of orthokeratology and 0.01% atropine sequential treatment in children and adolescents, as compared to continuous treatment with…
- Trial name
- NCT06667037
- Testing
- Ortho-k lenses, 0.01% Atropine
- Where
- China
- Volunteers
- 112 people
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Myopia
Myopia Control Efficacy of Second-generation DIMS Spectacle Lenses on Fast Progressing Myopes - Auxiliary Group
The purpose of this study is to examine the efficacy and performance of the Defocus Incorporated Multiple Segments (DIMS) and a variant of DIMS (D2) spectacle lenses on controlling myopia progression in fast progressing myopic…
- Trial name
- NCT05888805
- Testing
- DIMS spectacle lens
- Where
- Hong Kong
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Myopia, Orthokeratology
The Relationship of Relative Corneal Refractive Power Shift and Axial Length in Adolescents With Orthokeratology Lens
Orthokeratology lens is an effective method for myopia control. This study analyzed the relationship between the relative corneal refractive power shift and change of axial length in adolescents with orthokeratology lens.
- Trial name
- NCT05348369
- Where
- China
- Volunteers
- 364 people
- Sponsor
- Tianjin Eye Hospital
Myopia
Evaluation of the Performance of AIR OPTIX® COLORS
The purpose of this study was to assess the ocular response to and performance of the cosmetically printed silicone hydrogel contact lens AIR OPTIX® COLORS compared to FRESHLOOK® COLORBLENDS.
- Trial name
- NCT01338402
- Testing
- Lotrafilcon B contact lens, Lotrafilcon B contact lens with color, Phemfilcon A contact lens with color
- Where
- Canada
- Volunteers
- 47 people
- Sponsor
- CIBA VISION
Myopia, Progressive
Crossover RCT of TAMER Lenses in Myopia Control
This study is a prospective, randomized, crossover clinical trial with a planned proposed enrollment of 120 Chinese male and female subjects aged 6-12 years without systemic or ocular diseases to follow up their cycloplegic…
- Trial name
- NCT06329986
- Testing
- TAMER Lens Spectacle, SV lenses
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Myopia, Hyperopia
Evaluation of Effectiveness of Correcting Refractive Error With Ready-made Spectacles
This research project will compare two methods of correcting refractive error (long or short-sightedness) with spectacle lenses.
- Conditions
- Myopia, Hyperopia, Astigmatism
- Trial name
- RECS (NCT00657670)
- Testing
- Ready-made spectacles, Spectacles
- Where
- 2 sites in China, India
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Myopia Progression, Axial Length, Eye
Low Dose Atropine Eye Drops in Myopic Egyptian Children
Previous Studies reported that low concentration atropine eye drops may be effective in increasing the choroidal blood flow and thickness and this slows myopia progression.
- Conditions
- Myopia Progression, Axial Length, Eye, Sclera Thickness
- Trial name
- LAMP (NCT06265454)
- Testing
- low dose atropine eye drops
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Ain Shams University
Scoliosis Idiopathic, Myopia
Zhejiang Adolescent Spine and Vision Health Cohort: A Longitudinal Database Analysis
The aim of study: 1. To investigate the prevalence of scoliosis, other spinal deformities, myopia, and visual impairments in adolescents (aged 6-18) in Zhejiang Province.
- Conditions
- Scoliosis Idiopathic, Myopia, Vision Disorders
- Trial name
- NCT06992622
- Where
- China
- Volunteers
- 73,000 people
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Myopia
Investigation of the Regulation of Retinal and Choroidal Blood Vessels in Various AL Based on WF SS-OCTA Detection With Changes in Body Position
This prospective observational study aims to understand the effects of different subaxial body positions on choroidal and retinal blood vessel density.
- Trial name
- NCT06587776
- Volunteers
- 60 people
- Sponsor
- Science and Technology Department of Sichuan Province
Hyperopia, Long Sight
Zimbabwe Eyecare And Learning(ZEAL):Formative Research on Hyperopia and Educational Outcomes in Primary School Children
The purpose of this study is to determine whether uncorrected or corrected long-sightedness (hyperopia) has an impact on reading skills, in Grade 2 or Grade 4 school-aged children from Mashonaland Central province of Zimbabwe…
- Trial name
- ZEAL (NCT05538182)
- Testing
- Spectacles
- Where
- Zimbabwe
- Volunteers
- 1,883 people, healthy volunteers welcome
- Sponsor
- Queen's University, Belfast