Clinical trials: Refractive Disorders
Myopia
Assessing the Performance of Lotrafilcon A Lenses During a Three Month Period
The purpose of this trial is to assess the performance of an investigational contact lens over a three month period.
- Trial name
- NCT00933166
- Testing
- Lotrafilcon A contact lens
- Volunteers
- 169 people
- Sponsor
- CIBA VISION
Myopia
A Singapore Study to Assess How Neurovision Improve the Vision of Adults With Low to Moderate Myopia
To evaluate the efficacy of NeuroVision NVC vision correction technology to improve the vision of subjects with Low and Moderate Myopia in Asian eyes in Singapore
- Trial name
- NCT00348075
- Testing
- Neurovision
- Where
- Singapore
- Sponsor
- Singapore National Eye Centre
Myopia, Progressive
A Unified Index to Predict the Success Probability of Myopia Control
Orthokeratology lenses (OK-lens) and multifocal contact lenses (MFCL) are optical devices designed to slow down the progression of myopia. Both treatments a long-term commitment from doctors and patients.
- Trial name
- NCT05773118
- Testing
- orthokeratology lens, multifocal soft contact lens, Single vision spectacles
- Volunteers
- healthy volunteers welcome
- Sponsor
- Nova Southeastern University
Myopia
Controlling Myopia Progression With Soft Contact Lenses
This study is to investigate whether novel soft contact lens optical designs can slow myopia progression.
- Trial name
- NCT00762970
- Testing
- Test Lens 1, Test Lens 2, Control Lens
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Myopia, Convergence Insufficiency
The Health-Related Quality of Life of the Patients With Symptomatic Convergence Insufficiency
This trial is an observational cohort study. Patients aged 8-15 years with symptomatic convergence insufficiency and 150 patients with symptomatic convergence insufficiency who had not received visual training were selected from…
- Trial name
- NCT05948046
- Testing
- Visual training in hospital
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Tianjin Eye Hospital
Myopia
Controlling Myopia Progression With Soft Contact Lenses
This study is to investigate whether novel soft contact lens optical designs can slow myopia progression.
- Trial name
- NCT01787760
- Testing
- Test Soft Contact Lens B, Test Soft Contact Lens C, Active Comparator
- Where
- Hong Kong
- Volunteers
- 221 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Astigmatism, Myopia
Effect of a Myopia Control Lens on the Astigmatism in Children
The goal of this clinical trial is to investigate over a one-year period the effect of myopia control spectacle lenses on astigmatism in children aged 6 to 13 years with myopia and astigmatism.
- Trial name
- MAC (NCT07810725)
- Testing
- Lenslet-based myopia control spectacle lens
- Volunteers
- 15 people
- Sponsor
- Essilor International
Hyperopia and Myopia
Eye Imaging for the Study of Childhood Myopia
Myopia (nearsightedness) is increasing worldwide and is becoming a serious public health problem. Studies estimate that by 2050, if no action is taken, almost half of the world's population will be myopic.
- Trial name
- SELENA (NCT07335146)
- Testing
- Ophtalmic measurements to estimate geometrical distances, MRI, Ophtalmic measurements to measure wavefront aberrations
- Where
- France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Essilor International
Myopia
Study on the Measurement of Retinal Blood Flow in Children
In order to provide reference for clinical application, the normal values of retinal blood flow parameters in Chinese healthy children were measured by oct-angiography.
- Trial name
- NCT04689503
- Where
- China
- Volunteers
- 1,200 people
- Sponsor
- Wenzhou Medical University
Myopia
Study of Safety and Effectiveness of the Boston Orthokeratology Shaping Lens in the Arise Orthokeratology Lens
The objective of this orthokeratology study is to evaluate the safety and effectiveness of the Arise Orthokeratology Lens with non-spherical posterior peripheral curves
- Trial name
- NCT05984290
- Testing
- orthokeratology lens
- Where
- 6 sites in United States
- Volunteers
- 90 people
- Sponsor
- Bausch & Lomb Incorporated
Renal Insufficiency, Chronic
Montelukast for Treatment of Uremic Pruritus
In this study hemodialysis patients that underwent dialysis thrice weekly screen for uremic pruritus and 80 patients that at least have refractive pruritus that lead to sleep and daily activity disorders enroll in this study.
- Trial name
- NCT02559388
- Testing
- Montelukast
- Volunteers
- 73 people
- Sponsor
- Shiraz University of Medical Sciences
Myopia
Effect of Orthokeratology Versus Spectacles on Myopia Progression in Chinese Children: A Crossover Trial
Orthokeratology is becoming popular for the treatment of myopia children. Many studies have shown that orthokeratology is effective in temporarily reducing refractive error, and is also helpful for controlling myopia progression.
- Trial name
- NCT02186184
- Testing
- Orthokeratology, Spectacle
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Beijing Tongren Hospital
Refraction Error, Myopia
Age and Refraction in Predicting Myopia Progression in COVID-19
To determine the longitudinal changes of age and refraction in predicting myopia progression with risk under the coronavirus disease 2019 (COVID-19) pandemic in a 3-year follow-up of a Chinese cohort.
- Trial name
- NCT05305274
- Testing
- screening
- Where
- China
- Volunteers
- 34,400 people, healthy volunteers welcome
- Sponsor
- Tianjin Eye Hospital
Myopia
Efficacy of Myopia-control Lenses in a Population of Young Adults : the OPTIMA Study
The goal of this clinical trial is to learn if myopia-control eyeglass lenses (Essilor® Stellest® 2.0) can slow down the progression of short-sightedness (myopia) in young adults, compared with standard single-vision lenses.
- Trial name
- OPTIMA (NCT07804043)
- Testing
- Essilor® Stellest® 2.0 myopia-slowing lenses, Standard lenses
- Where
- France
- Volunteers
- 134 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Juvenile Myopia
Control of Myopia Using Novel Spectacle Lens Designs
Randomized, controlled, multisite, subject-and observer-masked, 3-arm parallel group clinical trial of 36-month duration to evaluate the safety and efficacy of a novel spectacle lens design in reducing the progression of juvenile…
- Trial name
- CYPRESS (NCT03623074)
- Testing
- Novel spectacle lens design, Spectacle lenses
- Where
- 14 sites in United States, Canada
- Volunteers
- 266 people, healthy volunteers welcome
- Sponsor
- SightGlass Vision, Inc.
Myopia
Lens Wear Schedules and End-of-Day Comfort
The purpose of this study was to assess the impact of lens-free (recovery) intervals of varying lengths on end-of-day comfort and tear film changes with daily contact lens wear.
- Trial name
- INVERMERE (NCT01433549)
- Testing
- Lotrafilcon B, Senofilcon A
- Where
- Canada
- Volunteers
- 44 people
- Sponsor
- CIBA VISION
Prematurity
Evaluation of Refractive Status and Ophthalmological Problems of Prematurity
Children born with very low birth weight and extremely low birth weight are at increased risk of various ophthalmic challenges such as retinopathy of prematurity (ROP), refractive error, strabismus, cerebral visual impairment…
- Trial name
- NCT01045616
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- National Taiwan University Hospital
Ametropia
Evaluation of the Performance of Non-molded Soft Contact Lenses
To evaluate the performance of the study soft lens for vision, comfort, physiology and lens surface properties.
- Trial name
- NCT00371787
- Testing
- Soft contact lens
- Where
- Canada
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Waterloo
Myopia
Red Light Intervention on Myopic Progression
To explore the effectiveness of using repeated low-level red-light therapy to slow myopia progression.
- Trial name
- NCT05203432
- Testing
- Red Light Intervention, Atropine
- Where
- China
- Volunteers
- 104 people
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Precocious Puberty, Early Puberty
Effect of Exogenous Growth Hormone on Ocular Findings
Body size and eye function play an essential role in adapting to the environment and human survival. Growth hormone is commonly recognized by its effect on the height of individuals; Although from an evolutionary perspective, the…
- Conditions
- Precocious Puberty, Early Puberty, Refraction Error
- Trial name
- NCT05338411
- Where
- 2 sites in Iran
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Isfahan University of Medical Sciences