Clinical trials: Refractive Disorders
Myopia
Increased Prevalence of Myopia in a Ophthalmologic Hospital in Goiânia - Goiás
The purpose of this study was to evaluate the increased prevalence of myopia among patients in different periods in an ophthalmologic hospital in Goiania.
- Trial name
- NCT02647411
- Volunteers
- 16,971 people
- Sponsor
- Instituto de Olhos de Goiania
Myopia, Progressive
To Evaluate the Efficacy and Safety of an Defocus Lens in Slowing the Progression of Myopia
To confirm the efficacy of DIMS lenses in controlling myopia progression, we planned a prospective, single-centre, randomised, double-blind, controlled, non-inferiority clinical study.
- Trial name
- NCT06405711
- Testing
- frame lens
- Where
- China
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- Tianjin Eye Hospital
Child, Motor Activity
CHAMPS Eye Study - Myopia and Retinal Vascular Geometry in Relation to Physical Activity
An increasingly physical inactive lifestyle in the Western World has led to a higher number of lifestyle -related diseases. The consequences are now already present in childhood with an increased prevalence of overweight…
- Conditions
- Child, Motor Activity, Myopia
- Trial name
- NCT02346006
- Testing
- More physical activity.
- Volunteers
- 307 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Astigmatism, Myopia
Short-term Study of Two Soft Contact Lenses in Wearers With Low Astigmatism
The primary objective of the study is to evaluate and compare the performance of two soft contact lens.
- Conditions
- Astigmatism, Myopia, Hyperopia
- Trial name
- NCT06873048
- Testing
- Control Contact Lens (stenfilcon A Sphere), Test Contact Lens (stenfilcon A Toric)
- Where
- Canada
- Volunteers
- 32 people
- Sponsor
- CooperVision International Limited (CVIL)
Myopia
Part-time Versus Full-time Spectacles for Myopia Control (ParMA Study)
The purpose is to assess the effect of part-time compared to full-time spectacle use in juvenile myopia control.
- Trial name
- NCT04854447
- Testing
- Single-Vision Spectacles
- Where
- Greece
- Volunteers
- 30 people
- Sponsor
- Aristotle University Of Thessaloniki
Myopia
Effects of Low-Level Red Light and Distant-Image Screen for Myopia Control in Children
This study aims to assess the efficacy and safety of daily exposure to 650-nm low-level red light (RL) and distant-image therapy (DIT) for myopia treatment.
- Trial name
- NCT06683287
- Testing
- red light and distant image screen, red light, distant image screen
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Beijing Tongren Hospital
Refractive Error
Clinical Investigation of Refraction Techniques
Prospective, multi-center, non-interventional, randomized, comparative clinical study to identify an optimal refractive technique that provides maximum plus refractive endpoint for best corrected distance visual acuity (BCDVA).
- Trial name
- NCT05461586
- Testing
- Refractive Technique (MR #1), Refractive Technique (MR #2)
- Where
- Australia
- Volunteers
- 35 people
- Sponsor
- Johnson & Johnson Surgical Vision, Inc.
Myopia
Myopia Progression After Ceasing Myopia Control Contact Lens Wear
This is a continuation study for subjects who were previously fit with test or control lenses; all will stop wearing their study lenses assigned in the previous study and will start to wear an FDA-approved marketed spherical soft…
- Trial name
- NCT01829230
- Testing
- 1 Day Acuvue Moist
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Myopia
Red Light Childhood Myopia Proof-of-concept
In this project the research team will begin to find out whether shining a red LED light at the eyes can slow down the worsening of short-sightedness in children.
- Trial name
- NCT06771258
- Testing
- Red Light (PDT)
- Where
- United Kingdom
- Volunteers
- 24 people
- Sponsor
- University College, London
Myopia, Myopic Astigmatism
A Clinical Trial Assessing the Safety and Effectiveness of Orthokeratology Lenses in Patients With Myopia and Myopic Astigmatism
This is a prospective, multi-centre, single-arm clinical trial to evaluate the effectiveness and safety of MCOK-01 lenses in patients with myopia and myopic astigmatism who need dioptric correction.
- Trial name
- SEMOA (NCT07047924)
- Testing
- MCOK-01
- Where
- 4 sites in Australia
- Volunteers
- 220 people
- Sponsor
- Menicon Co., Ltd.
Myopia
Effectiveness of DIMS Spectacle as a Function of the Age
Purpose: To evaluate the effectiveness of Defocus Incorporated Multiple Segments (DIMS) in slowing myopia progression as a function of age in pediatric patients.
- Trial name
- NCT06556849
- Testing
- Defocus Incorporated Multiple Segments (DIMS)
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- Luca Buzzonetti
Refractive Error, Dry Eye
Determination of Cell Population in Solution-Induced Corneal Staining (SICS) and Symptomatic Versus Asymptomatic Lens Wearers
The purpose of the study is to investigate the corneal epithelial cell response associated with lens wear that results in solution-induced corneal staining (Phase1) and to determine the cell appearance in symptomatic and…
- Trial name
- ABBOTSFORD (NCT01629706)
- Testing
- Balafilcon A contact lens, Habitual contact lenses, Renu multi-purpose solution
- Volunteers
- 92 people
- Sponsor
- CIBA VISION
Dry Eye Disease
Assess the Effects of Spectacles or Orthokeratology on Dry Eye Parameters in Children and Adolescents.
Orthokeratology(OK) is currently one of the effective methods for treating myopia, reshaping the corneal epithelium to change refractive power.
- Trial name
- NCT06023108
- Testing
- Orthokeratology, Spectacles
- Where
- China
- Volunteers
- 300 people
- Sponsor
- He Eye Hospital
Myopia, Myopia; Refractive Error
Efficacy and Visual Quality of Orthokeratology Lenses With Different Designs
Orthokeratology (ortho-k) lens is very effective in slowing down axial elongation in myopic children by 30% to 63% when compared to children wearing single-vision spectacles or contact lenses.
- Trial name
- NCT06825585
- Testing
- Orthokeratology with 5.0mm back optical zone diameter, Orthokeratology with a 6.2 mm back optical zone diameter
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Xiaoyan Yang
Myopia
The Use of Atropine 0.01% in the Prevention and Control of Myopia (ATOM3)
Study of low dose atropine in preventing the onset and progression of myopia in high risk children with pre-myopia or low-myopia.
- Trial name
- NCT03140358
- Testing
- Atropine sulfate 0.01%
- Where
- Singapore
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Singapore National Eye Centre
Myopia, Progressive, Atropine Allergy
Eye Drops Study for Myopia Control in Schoolchildren
The myopia prevalence in schoolchildren is high in Taiwan. The myopia progression is fast in children and often associated high myopia in later life.
- Trial name
- NCT03402100
- Testing
- eye drops
- Where
- Taiwan
- Volunteers
- 150 people
- Sponsor
- Chang Gung Memorial Hospital
Multimorbidity, Comorbidity
A Study on the Effectiveness of Comprehensive Intervention Based on Specialized Physical Education Courses in the Prevention of Comorbidity Among Junior Middle School Students
Junior high school students are in a critical period of physical and mental development, currently facing two major health challenges: first, persistently high rates of myopia with a noticeable trend toward younger onset; second…
- Conditions
- Multimorbidity, Comorbidity, Common Diseases in Children and Adolescents, Myopia
- Trial name
- NCT07237698
- Testing
- The intervention group participated in specialized physical education courses.
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Xiaoyan Wu
Myopia, Myopia; Refractive Error
Peripheral Relative Refractive Power of Orthokeratology Lenses
Orthokeratology (OK) has been demonstrated to be an effective intervention for slowing axial elongation in children with myopia.
- Trial name
- NCT07294404
- Testing
- orthokeratology
- Where
- China
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Tianjin Eye Hospital
Refractive Errors, Myopia (Disorder)
Environmental Health and Myopia Prevention and Control
Myopia is one of the major causes of low visual acuity during childhood. It is generally more prevalent in urban areas than in rural areas.
- Trial name
- NCT04161326
- Where
- China
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Myopia
Efficacy of Chinese Ocular Exercise on Visual Acuity and Ocular Accommodation in Myopic Teenager
To assess whether Chinese ocular exercise is effective in altering distant and near visual acuity, ocular accommodation and visual symptoms in myopic teenager, and thus might have the possibility of slowing myopia progression in…
- Trial name
- NCT01756287
- Testing
- Chinese ocular exercise
- Where
- China
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Beijing Tongren Hospital