Clinical trials: Refractive Disorders
Dry Eye
The Effect Of Lifitegrast On Refractive Accuracy And Symptoms In Dry Eye Patients Undergoing Cataract Surgery
To determine if Xiidra® lifitegrast plays a role in the refractive accuracy when administered to patients preoperatively who are scheduled for cataract surgery and have a tear break up time (TBUT) ≤ 10 seconds and central corneal…
- Trial name
- NCT03866629
- Testing
- Lifitegrast
- Where
- United States
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- MDbackline, LLC
Refractive Errors
Clinical Validation Study Protocol for SmartEyes Smart Optometry Measurement Device (Medical Device Clinical Validation Study)
This study aims to evaluate the SmartEyes smart refraction measurement device in two phases under real outpatient optometry room visits at Wuhan Children's Hospital.
- Trial name
- CVSP-SOMD (NCT07803094)
- Testing
- SmartEyes smart refraction measuring device, Topcon KR800, Subjective refraction
- Volunteers
- 200 people
- Sponsor
- The Hong Kong Polytechnic University
Congenital Cataract, Pediatric Cataract
Five-Year Visual Function and Refractive Outcomes After Congenital Cataract Surgery
This prospective multicenter observational study aims to evaluate the 5-year visual function and refractive outcomes in children undergoing surgery for congenital cataract.
- Trial name
- NCT07070037
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Jin Yang
Accomodation, Biofeedback Training
Assessment of Accommodation Behavior in Children Under Myopia Control Treatment (Pilot Study)
This study will examine the accommodative behavior in children undergoing myopia control treatments. A subset of children showing reduced accommodation, known to occur in while wearing multifocal soft contact lenses (MFCL) from…
- Conditions
- Accomodation, Biofeedback Training, Myopia
- Trial name
- NCT04807361
- Testing
- Auditory biofeedback traing
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- State University of New York College of Optometry
Myopia, Progressive
Clinical Evaluation of MyoCare in Europe (CEME)
A 2-year prospective, multicenter, randomized controlled, and double-blind clinical trial is used to investigate the efficacy of a new design of ophthalmic lenses to slow the progression of myopia.
- Trial name
- CEME (NCT05919654)
- Testing
- MyoCare, ClearView
- Where
- Spain
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Universidad Complutense de Madrid
Myopia
Daily Disposable Comparison Study
The objective of the study is to compare the overall subjective preference between two Daily Disposable hydrogel lenses when refitted into a third hydrogel lens.
- Trial name
- NCT02094677
- Testing
- filcon II 3, etafilcon A, nelfilcon A
- Where
- Canada
- Volunteers
- 70 people
- Sponsor
- CooperVision, Inc.
Myopia, Progressive
To Evaluate the Efficacy and Safety of an Defocus Lens in Slowing the Progression of Myopia
To confirm the efficacy of DIMS lenses in controlling myopia progression, we planned a prospective, single-centre, randomised, double-blind, controlled, non-inferiority clinical study.
- Trial name
- NCT06405711
- Testing
- frame lens
- Where
- China
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- Tianjin Eye Hospital
Keratoconus, Ectasia
Safety and Effectiveness of Corneal Crosslinking (CXL): Keratoconus and Post-Refractive Ectasia
This prospective, randomized study is being conducted to evaluate the safety and effectiveness of corneal cross-linking (CXL) in patients with keratoconus or post-refractive ectasia (post-LASIK or PRK) utilizing two techniques…
- Trial name
- CXL (NCT03080077)
- Testing
- Ricrolin+, Epi-Off
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Myopia, Progressive, Atropine Allergy
Eye Drops Study for Myopia Control in Schoolchildren
The myopia prevalence in schoolchildren is high in Taiwan. The myopia progression is fast in children and often associated high myopia in later life.
- Trial name
- NCT03402100
- Testing
- eye drops
- Where
- Taiwan
- Volunteers
- 150 people
- Sponsor
- Chang Gung Memorial Hospital
Myopia
Effect of Low-level Red-light on Ultra-high Myopia
100 eyes of ultra-high myopia were treated with daily low-level red-light. The age of children ranged from 3 to 16.3 years. The follow-up duration was one year.
- Trial name
- NCT06738095
- Testing
- daily low-level red-light
- Where
- China
- Volunteers
- 57 people
- Sponsor
- Beijing Tongren Hospital
Ametropia
Contact Lens Wettability
The purpose of this study is to compare the wettability of contact lenses disinfected with three marketed contact lens care solutions.
- Trial name
- NCT00349063
- Testing
- soft contact lens, Soft contact lens multipurpose disinfection regimen
- Where
- Canada
- Volunteers
- 55 people
- Sponsor
- University of Waterloo
Full Spectrum
A Self-controlled Study of the Effect of Partial Spectral Absence of Visible Light on the Pupil
Previous studies have shown that the spectrum of light influences myopia. LED lights with a partially absent light spectrum increase the risk of myopia progression compared to LEDs with a full spectrum, potentially mediated by…
- Trial name
- NCT06501131
- Testing
- full-spectrum light exposure, specific spectrum absence light exposure
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Myopia
MiSight 1 Day Post-Approval Study for Effectiveness and Visual Symptoms
The purpose of this post-approval study is to confirm the effectiveness of the MiSight 1 Day lens in clinical practices within the US and to assess the stability of the myopia reduction over one-year post-treatment.
- Trial name
- NCT05285553
- Testing
- MiSight 1 Day, Proclear 1 day
- Where
- 30 sites in United States
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Presbyopia
A Clinical Trial to Evaluate the Safety and Effectiveness of the Raindrop Near Vision Inlay for Pseudophakic Subjects
The objective of this study is to evaluate the safety and effectiveness of the Raindrop Near Vision Inlay implanted in bilateral pseudophakes with presbyopia for improvement of near and intermediate vision.
- Trial name
- NCT03017612
- Testing
- Raindrop Near Vision Inlay
- Where
- 6 sites in United States
- Volunteers
- 13 people
- Sponsor
- ReVision Optics, Inc.
Myopia, Healthy
Proteomic Analysis on Myopic Children Using Orthokeratology Lenses With Good or Poor Myopic Control
The key objective of the study is to gain an understanding of the biochemical processes that contribute to orthokeratology lenses being more effective in specific individuals compared to others.
- Conditions
- Myopia, Healthy, Orthokeratology
- Trial name
- ProMOC (NCT06647472)
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- Vejle Hospital
Refractive Errors, Accomodation
Study in Pediatric Volunteers of a Handheld Device Versus a Standard Diagnostic Device in Ophthalmic Refraction
This study is exploratory and examines whether the refraction results obtained from a novel optical device yields results similar to the ophthalmic refraction measurements obtained from an autorefractor in children.
- Conditions
- Refractive Errors, Accomodation, Diagnostic Self Evaluation
- Trial name
- NCT04955379
- Testing
- EQ103
- Where
- Israel
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- EyeQue Corp.
Myopia, Refractive Errors
Effect of Repeated Low-Level Red-Light Therapy on Retinal Function and Structure
The purpose of this clinical trial is to evaluate the effect of repeated low-level red-light (RLRL) therapy on the retinal function and structure among myopic teenagers.
- Conditions
- Myopia, Refractive Errors, Eye Diseases, Retina; Change
- Trial name
- NCT05597397
- Testing
- RLRL
- Where
- China
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Myopia
Study of Safety and Effectiveness of the Boston Orthokeratology Shaping Lens in the Arise Orthokeratology Lens
The objective of this orthokeratology study is to evaluate the safety and effectiveness of the Arise Orthokeratology Lens with non-spherical posterior peripheral curves
- Trial name
- NCT05984290
- Testing
- orthokeratology lens
- Where
- 6 sites in United States
- Volunteers
- 90 people
- Sponsor
- Bausch & Lomb Incorporated
Myopia, Mental Health
A Study of the Impact of Digital Intervention on Parents/primary Caregivers' Myopia Prevention and Control Health Literacy on Preschoolers' Myopia and Physical and Mental Health
The study is a Randomized controlled trial based on digital interventions, involving pre-school children and their parents or major caregivers.
- Conditions
- Myopia, Mental Health, Obesity
- Trial name
- NCT06620250
- Testing
- Digital Prevention and control of myopia
- Volunteers
- 882 people, healthy volunteers welcome
- Sponsor
- Fangbiao Tao
Myopia
Pilot Study to Assess the Efficacy of Short Exposure to Defocus to Slow the Progression of Myopia in Children
The objective of this pilot study is to establish whether brief periods of high levels of acutely imposed myopic defocus can be used to slow the progression of myopia in children, as measured by changes in spherical equivalent…
- Trial name
- NCT00400140
- Testing
- Hyperopic lens
- Where
- Singapore
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Singapore National Eye Centre