Clinical trials: Refractive Error
Myopia
Using Contact Lenses and Spectacle Lenses as Myopia Interventions.
Effect of alternating contact lenses and spectacles for myopia control.
- Trial name
- NCT07845721
- Testing
- Test Spectacle Lens & Contact Lens, Control Spectacle Lens & Contact Lens
- Where
- 2 sites in Canada, United Kingdom
- Volunteers
- 58 people
- Sponsor
- CooperVision International Limited (CVIL)
Amblyopia, Refractive Errors
Vision Screening for the Detection of Amblyopia
INTRODUCTION. Amblyopia is defined as the loss of visual acuity (VA) in one or both eyes, without any obvious structural or pathological anomalies.
- Conditions
- Amblyopia, Refractive Errors, Anisometropia, Strabismus
- Trial name
- NCT01430247
- Testing
- Amblyopia screening
- Where
- Croatia
- Volunteers
- 7,000 people
- Sponsor
- Mladen Busic
Myopia
Visual Performance of Center Distance Daily Disposable Multifocal Lenses
The purpose of this study is to compare visual performance (high and low contrast acuity, reading acuity, contrast sensitivity, stereoacuity, accommodative response, eye hand coordination, far near vision, and dynamic vision)…
- Trial name
- ViPCD3 (NCT06475053)
- Testing
- NaturalVue Enhanced Multifocal 1 Day contact lens, MiSight 1 Day contact lens
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Visioneering Technologies, Inc
Near Vision, Refractive Error Correction
Clinical Outcomes of the Use of a Femtosecond Laser Treatment in a Patient With Implanted Monofocal IOLs
This study aims to assess the safety and efficacy of evaluating near vision or refractive error in eyes implanted with a mono focal intraocular lens (IOL) using a low-energy femtosecond laser.
- Trial name
- NCT07447622
- Testing
- Device
- Where
- Czechia
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Perfect Lens, LLC
Nearsightedness, Farsightedness
Advanced Surface Ablation (ASA) vs Laser-Assisted In Situ Keratomileusis (LASIK)
The purpose of this combined retrospective and prospective chart review analysis is to investigate the safety, efficacy, and predictability obtained via Laser-Assisted In Situ Keratomileusis (LASIK) and Advanced Surface Ablation…
- Conditions
- Nearsightedness, Farsightedness, Astigmatism
- Trial name
- NCT00778570
- Where
- Canada
- Volunteers
- 4,000 people
- Sponsor
- Ottawa Hospital Research Institute
Refractive Errors
Post-market Clinical Follow-up Study of Alcon PRECISION1™ Spherical and PRECISION1™ for Astigmatism Soft Contact Lenses
The purpose of this study is to assess long term performance and safety of verofilcon A soft contact lenses in a real-world setting in a population of 7 years or older having at least 1 year of verofilcon A (sphere or toric)…
- Trial name
- NCT06462456
- Testing
- Verofilcon A spherical soft contact lenses, Verofilcon A toric soft contact lenses
- Where
- 12 sites in United States
- Volunteers
- 140 people
- Sponsor
- Alcon Research
Myopia
A Comparison of AIR OPTIX® COLORS Versus FRESHLOOK® COLORBLENDS
The purpose of this study was to evaluate the overall comfort of AIR OPTIX® COLORS compared to FRESHLOOK® COLORBLENDS in habitual wearers of the FRESHLOOK® COLORBLENDS .
- Trial name
- NCT01635933
- Testing
- Lotrafilcon B contact lens with color, Phemfilcon A contact lens with color
- Volunteers
- 370 people
- Sponsor
- Alcon Research
Myopia
Tolerability of a Novel Spectacle Design With Reduced Peripheral Contrast
Prospective, randomized, subject-masked 3-arm clinical study to assess the pediatric acceptability across three iterations of a novel spectacle lens design.
- Trial name
- WALNUT (NCT03761758)
- Testing
- Spectacle lenses
- Where
- Canada
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- SightGlass Vision, Inc.
Myopia
An Evaluation of the Effectiveness of Dual Focus Soft Contact Lenses in Slowing Mypoia Progression
The purpose of this study is to determine whether a new type of soft contact lens with a unique optical design (dual focus) is effective at slowing the progression of myopia (near-sightedness) in children.
- Trial name
- NCT01729208
- Testing
- Dual Focus Soft Contact Lens, Single Vision Soft Contact Lens
- Where
- 4 sites in Canada, Portugal and 2 more
- Volunteers
- 144 people
- Sponsor
- CooperVision, Inc.
Myopia
Efficacy and Influencing Factors of Repeated Low-level Red-light in Myopia
To evaluate the long-term efficacy of repeated low-level red-light (RLRL) therapy in the prevention and control of myopia in children, and to analyze the key factors influencing its efficacy (such as individual differences and…
- Trial name
- RLRL (NCT07104513)
- Testing
- Red Light
- Where
- 2 sites in China
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Ruihua Wei
Myopia, Progressive, Children, Only
Long-term Efficacy of Orthokeratology Contact Lens Wear in Controlling the Progression of Childhood Myopia
To assess the long-term efficacy of the Menicon Z Night orthokeratology contact lens in controlling the progression of childhood myopia
- Trial name
- MCOS7 (NCT04806698)
- Testing
- Menicon Z Night, Control
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Menicon Co., Ltd.
Myopia, Myopia Progression
The P.A.U.S.E.® Spectacle Study
The goal of this clinical trial is to learn if spectacle lenses using Phase Alteration Utilising Sub Elements (P.A.U.S.E.®) technology works to slow down the rate of myopia progression in myopic children.
- Trial name
- NCT06577948
- Testing
- Single vision spectacle lens, P.A.U.S.E. spectacle lens 1, P.A.U.S.E. spectacle lens 2
- Where
- Vietnam
- Volunteers
- 205 people
- Sponsor
- nthalmic Pty Ltd
Myopia, Hyperopia
Bilateral Dispensing Study of Fanfilcon A Toric Versus Enfilcon A Toric Lenses
Bilateral dispensing clinical trial of fanfilcon A toric lens verses enfilcon A toric lens over two weeks.
- Conditions
- Myopia, Hyperopia, Astigmatism
- Trial name
- NCT02423109
- Testing
- fanfilcon A, enfilcon A
- Where
- 2 sites in United States, Canada
- Volunteers
- 44 people
- Sponsor
- CooperVision, Inc.
Myopia, Progressive
Near Horizontal Heterophoria in Chinese Children
This study aimed to assess the association of refraction and axial length with near-horizontal heterophoria in a large population-based study of school-aged Chinese children.
- Trial name
- NCT05007626
- Testing
- axial length and refractive error
- Where
- China
- Volunteers
- 15,081 people, healthy volunteers welcome
- Sponsor
- Tianjin Eye Hospital
Myopia
Examination of Myopia Progression and Soft Bifocal Contact Lens Myopia Control
This project intends to provide important, previously unmet answers regarding biological associations with myopia (nearsightedness) progression in order to improve the ability to predict patients who are most likely to benefit…
- Trial name
- BLINK2 (NCT04080128)
- Testing
- Contact lenses
- Where
- 2 sites in United States
- Volunteers
- 248 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Macula Hole, Retinal Detachment
Amniotic Membrane for Recurrent Macular Hole
Macular hole surgery were tried by different surgeons using many techniques with different successes but still there were many recurrences.
- Conditions
- Macula Hole, Retinal Detachment, Myopic Macular Degeneration
- Trial name
- NCT03528122
- Testing
- Recurrent opened macular hole
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Minia University
Myopia
Control of Myopia in Young Children Using H.O.P.E. Lenses Combined With 0.02% Atropine Eye Drops
A multicenter, prospective, intervention study on the control of myopia in young children using high-order phase element array microstructure lenses (H.O.P.E.) in combination with low-concentration atropine eye drops (0.02%)
- Trial name
- NCT07846787
- Testing
- High-order Phase Element Array Microstructure Design Lens (H.O.P.E.), 0.02% Atropine Sulfate Eye Drops
- Where
- China
- Volunteers
- 264 people
- Sponsor
- Ruihua Wei
Myopia
Family Myopia Study
This study will try to identify the gene or genes responsible for myopia (nearsightedness) and to examine the relationship between myopia and near work.
- Trial name
- NCT00341549
- Where
- United States
- Volunteers
- 7,477 people
- Sponsor
- National Human Genome Research Institute (NHGRI)
Myopia
A Clinical Trial to Evaluate the Efficacy and Safety of Defocusing Lenses in Delaying Myopia Progression
The objective of this clinical trial was to evaluate the efficacy and safety of defocusing lenses for delaying myopia progression in children and adolescents.
- Trial name
- NCT06411717
- Testing
- Microstructure lens A, Microstructure lens B, Control group
- Where
- China
- Volunteers
- 156 people
- Sponsor
- Suzhou Care-Real Medical Technology Co., Ltd.
Myopia
Short-term Clinical Performance of Multifocal Soft Contact Lens
The study is aimed to observe the short-term clinical performance of MiSight™ multifocal soft contact lens compared with Proclear™ 1day, including objective examination, subjective acceptability of wearers, and doctors'…
- Trial name
- NCT05273606
- Testing
- MiSight mutifocal soft contact lens, Proclear 1 Day soft contact lens
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University