Clinical trials: Refractive Error
Myopia
Efficacy and Influencing Factors of Repeated Low-level Red-light in Myopia
To evaluate the long-term efficacy of repeated low-level red-light (RLRL) therapy in the prevention and control of myopia in children, and to analyze the key factors influencing its efficacy (such as individual differences and…
- Trial name
- RLRL (NCT07104513)
- Testing
- Red Light
- Where
- 2 sites in China
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Ruihua Wei
Myopia
Delaying the Onset of Nearsightedness Until Treatment Study
Participants eligible for the study will be randomized to one of three concentrations of atropine and followed for a month.
- Trial name
- DONUT (NCT06029530)
- Testing
- Atropine Ophthalmic
- Volunteers
- healthy volunteers welcome
- Sponsor
- Ohio State University
Myopia
Influence of Corneal Biomechanical Properties on Myopia Control
to analyze the changes in corneal biomechanics of myopic children with different treatment (low concentration atropine eye drops and orthokeratology) and explore the possible mechanism of myopia control
- Trial name
- NCT05090592
- Testing
- orthokeratology, 0.01 atropine
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Buddhist Tzu Chi General Hospital
Myopia, Astigmatism
An Outcomes Study Comparing the Intralase FS 60 to the Intralase iFS When Performing LASIK Surgery for Nearsightedness
The purpose of the study is to compare the results of LASIK surgery when using two versions of a femtosecond laser in patients with nearsightedness with and without astigmatism.
- Trial name
- NCT01365728
- Testing
- LASIK with the iFS femtosecond laser
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Stanford University
Refractive Errors
Comparison of Visual Acuity Performed in Office Versus In Residence
GoCheck has developed and deployed a home-based visual acuity test that may be used in-office or in residence. The test methodology utilizes modified ATS and ETDRS protocols with Sloan optotypes, crowding bars and sophisticated…
- Trial name
- VA IR vs IO (NCT05250986)
- Testing
- GoCheck Kids (iOS), GoCheck Kids (Windows), GoCheck at Home (iOS)
- Where
- 4 sites in United States, Israel
- Volunteers
- 325 people, healthy volunteers welcome
- Sponsor
- Gobiquity Mobile Health
Myopia
Cambridge Anti-Myopia Trial: Accommodation Training and Aberration Control in Myopia Development
We have identified focussing problems related to myopia getting worse. Our trial uses optical and orthoptic interventions that correct the focussing problems to see if this retards myopia progression.
- Trial name
- NCT00317551
- Testing
- Aberration controlled contact lens, Vision training
- Where
- United Kingdom
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Anglia Ruskin University
Hyperopic Astigmatism
Effect of WRAD Lens on Axial Growth and Refraction in Low-hyperopic Chinese Children
Myopia is one of the most common visual impairments worldwide.This not only poses long-term risks to individual health but also imposes significant medical and economic burdens on society.
- Trial name
- NCT07682974
- Testing
- With-the-Rule Astigmatic Defocus Lens, With-the-Rule Astigmatic Defocus Lens (Non-plano), Single Vision
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- He Eye Hospital
Myopia, High Myopia
The Monitoring and Intervention of Refractive Changes in Children and Teenagers in Tianjin
The study aimed to collect multi-factor information on school-age children with pre-clinical myopia, and to identify the initial factors and warning signs of myopia.
- Trial name
- NCT05691296
- Testing
- Home training, School training
- Where
- China
- Volunteers
- 4,000 people
- Sponsor
- Tianjin Eye Hospital
Retinopathy of Prematurity
Refractive Error and Biometry in Retinopathy of Prematurity
The investigators compared long-term refractive and biometric outcomes in children with retinopathy of prematurity who received two different anti-vascular endothelial growth factor agents.
- Trial name
- NCT03334513
- Testing
- Bevacizumab, Ranibizumab
- Volunteers
- 35 people
- Sponsor
- San Ni Chen
Myopia, Progressive
Clinical Study of Light Therapy to Control Myopia Progression in Children
Low-lever red light therapy (LLLT) has been used to control myopia progression in China for a few years besides amblyopia therapy for a few decades.
- Trial name
- NCT05761379
- Testing
- Photobiomodualtion Therapy, Single vision spectacles for correction myopia
- Where
- China
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Beijing Airdoc Technology Co., Ltd.
Myopia, Myopia, Progressive
Multicenter RCT: LED Red Light Dose-Response in Myopia Progression Control
The goal of this clinical trial is to verify the effectiveness and safety of non-laser LED red light combined with defocus lens therapy for controlling myopia progression and evaluate the impact of different intervention…
- Trial name
- NCT07330180
- Testing
- Yingtong Vision Rehabilitation Instrument, Hoya DIMS multi-point myopia defocus lens
- Where
- 7 sites in China
- Volunteers
- 364 people, healthy volunteers welcome
- Sponsor
- Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Refractive Errors, Myopia (Disorder)
Environmental Health and Myopia Prevention and Control
Myopia is one of the major causes of low visual acuity during childhood. It is generally more prevalent in urban areas than in rural areas.
- Trial name
- NCT04161326
- Where
- China
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Myopia
Control of Myopia in Young Children Using H.O.P.E. Lenses Combined With 0.02% Atropine Eye Drops
A multicenter, prospective, intervention study on the control of myopia in young children using high-order phase element array microstructure lenses (H.O.P.E.) in combination with low-concentration atropine eye drops (0.02%)
- Trial name
- NCT07846787
- Testing
- High-order Phase Element Array Microstructure Design Lens (H.O.P.E.), 0.02% Atropine Sulfate Eye Drops
- Where
- China
- Volunteers
- 264 people
- Sponsor
- Ruihua Wei
Myopia
The Evaluation of Safety and Myopia Progression Control Using Novel Spectacle Lens
The goal of this clinical trial is to test Novel spectacle lenses in myopic children. The main question it aims to answer are: safety and efficacy of the lenses.
- Trial name
- NCT05886348
- Testing
- Model-A Novel spectacle lens, Model-B Novel spectacle lens, Single vision spectacle lens
- Where
- 5 sites in China
- Volunteers
- 249 people, healthy volunteers welcome
- Sponsor
- HOYA Lens Thailand LTD.
Myopia
The Effect of Sun-like Spectrum With Different Spectrum Composition on Retinal Blood Flow
In 2020, the overall myopia rate among children and adolescents was 52.7% in China. The COVID-19 pandemic has increased students' time of indoor eye-using, and it showed that the light exposure intensity of myopic students is…
- Trial name
- NCT05594719
- Testing
- Shorter-wavelength dominant light, Light similar to the solar spectrum proportion, Longer-wavelength dominant light
- Where
- 2 sites in China
- Volunteers
- 75 people
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Astigmatism
Neural Mechanisms Underlying Astigmatism
This study is to compare the contrast sensitivity function and neural response to gratings before and after the orientation discrimination task in the astigmatism or amblyopia patients.
- Trial name
- NCT03735602
- Testing
- perceptual training
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Myopia
Effects on Ocular Parameters of Myopic Eyes After Orthokeratology in Myopic Children
Effects on Ocular Parameters of Myopic Eyes After Orthokeratology in Myopic Children
- Trial name
- NCT03516357
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Myopia, Myopia Progression
Comparing Myopia Control Spectacle Lenses and Standard Single Vision Spectacle Lenses in Children With Myopia
The purpose of this clinical trial is to compare a new myopia control spectacle lens with a standard single vision spectacle lens in slowing the progression of myopia (nearsightedness) in healthy children aged 6 to under 11…
- Trial name
- PEARL (NCT07839091)
- Testing
- Investigational Myopia Control Spectacle Lens, Single Vision Spectacle Lens
- Where
- Singapore
- Volunteers
- 20 people
- Sponsor
- Essilor International
Myopia
Binocular Peripheral Myopic Defocus Using a Clinical Prototype Device
Kubota Vision Inc. has developed a spectacle-like prototype device which is designed to be used as a light-based therapy to reduce myopia progression.
- Trial name
- NCT05425108
- Testing
- Binocular CP1
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Kubota Vision Inc.
Myopia
Ambient Light Levels in the Kindergarten and Schools and the Relation to Refractive Development
Myopia, the most common human eye disorder, is a phenomenon characterized by an unconstrained elongation of the eye globe There are number of theories concerning the environmental effect on the emmetropization process, most are…
- Trial name
- NCT02854891
- Testing
- autorefractometer, A-scan ultrasound
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Hillel Yaffe Medical Center