Clinical trials: Refractive Error
Astigmatism, Myopia
Evaluation of Two Daily Disposable Contact Lenses for Wearers With Astigmatism
The purpose of this trial is to compare the performance of two contact lenses for contact lens wearers with astigmatism.
- Trial name
- NCT01207466
- Testing
- Nelfilcon A investigational contact lens, Nelfilcon A commercial contact lens
- Volunteers
- 95 people
- Sponsor
- CIBA VISION
Myopia, Hyperopia
Daily Disposable Performance of 1•DAY ACUVUE® TruEye™ and 1•DAY ACUVUE® MOIST® With LACREON® TECHNOLOGY
This study is an observational registry of patients who have recently been prescribed 1•DAY ACUVUE® TruEye® or 1•DAY ACUVUE® MOIST® Brand Contact Lenses with LACREON® TECHNOLOGY.
- Trial name
- TEMPO (NCT01467557)
- Testing
- narafilcon B daily disposable soft contact lenses, etafilcon A daily disposable soft contact lenses
- Where
- 37 sites in United States
- Volunteers
- 1,171 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Myopia, Cornea
Euclid Phoenix Lens Design Trial 2
Lens wettability and subjective comfort of Euclid orthokeratology lenses with and without an enhanced coating will be compared in 50 children. Axial elongation will be monitored in pediatric patients who qualify and consent.
- Trial name
- NCT06392607
- Testing
- Euclid orthokeratology (standard coating), Euclid orthokeratology (enhanced coating)
- Where
- 5 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Euclid Systems Corporation
Myopia
Non-dispense Comfort Comparison of Two Silicone Hydrogel Lenses
The purpose of this study is to compare subjective responses to two contact lenses after 15 minutes of wear.
- Trial name
- NCT00808834
- Testing
- Lotrafilcon A contact lens, Senofilcon A contact lens
- Volunteers
- 196 people
- Sponsor
- CIBA VISION
Myopia
The Evaluation of Safety and Myopia Progression Control Using Novel Spectacle Lens
The goal of this clinical trial is to test Novel spectacle lenses in myopic children. The main question it aims to answer are: safety and efficacy of the lenses.
- Trial name
- NCT05886348
- Testing
- Model-A Novel spectacle lens, Model-B Novel spectacle lens, Single vision spectacle lens
- Where
- 5 sites in China
- Volunteers
- 249 people, healthy volunteers welcome
- Sponsor
- HOYA Lens Thailand LTD.
Myopia
Dehydration of Stenfilcon A Contact Lenses Versus Delefilcon A Contact Lenses
The study will explore in vivo lens dehydration rates across a 12hr wear period for the study lenses.
- Trial name
- NCT02366923
- Testing
- stenfilcon A, delefilcon A
- Where
- Canada
- Volunteers
- 28 people
- Sponsor
- CooperVision, Inc.
Myopia
the Efficacy of 0.01% Atropine for Near Work-induced Transient Myopia and Myopic Progression
Near work-induced transient myopia (NITM) is an important factor in permanent myopia (PM) development and progression. Atropine eye drop is beneficial in reducing initial NITM and slowing down myopic progression.Participants were…
- Trial name
- NCT06034366
- Testing
- 0.01% atropine, 0.9% sodium chloride
- Where
- 2 sites in China
- Volunteers
- 150 people
- Sponsor
- He Eye Hospital
Amblyopia, Anisometropic, Pediatric
Multimodal Therapy in Anisometropic Amblyopia
This study aims to evaluate whether a six-month app-based visual therapy program, called AmblyoPlay, can improve visual acuity, oculomotor skills, and balance in children with anisometropic amblyopia (a type of "lazy eye" caused…
- Conditions
- Amblyopia, Anisometropic, Pediatric, Postural Balance, Vision Therapy
- Trial name
- MUTA (NCT07093840)
- Testing
- AmblyoPlay Digital Visual Therapy, control group
- Where
- Turkey (Türkiye)
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Yusa Basoglu
Myopia
The Different Design of Orthokeratology
In this study, we intend to enroll orthokeratology subjects aged 8-18 years old with binocular myopia up to and including -4.00 D.
- Trial name
- NCT05956704
- Testing
- Orthokeratology with aspheric wide inversion zone design in the optical zone, Orthokeratology with traditional spherical design in the optical zone
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Tianjin Eye Hospital
Myopia, Outdoor Activity
Vision Care Intervention for Lower Grade School Children in Taiwan
The purpose of this study is making use of school policy- recess outside classroom (ROC7-11) for increasing the time spent outdoor during recess and encouraging children spent time outdoor up to 11 hours in each week to…
- Conditions
- Myopia, Outdoor Activity, Policy of Recess Outside Classroom
- Trial name
- NCT02082743
- Testing
- Outdoor activity in recess time
- Where
- Taiwan
- Volunteers
- 1,020 people
- Sponsor
- Chang Gung Memorial Hospital
Myopia
Subjective Evaluation of a Commercially Marketed Contact Lens Amongst a Subset of the Contact Lens Wearing Population
The purpose of this study is to compare the performance of commercially marketed contact lenses to habitual contact lenses in a selected segment of the contact lens wearing population.
- Trial name
- NCT01007916
- Testing
- Lotrafilcon B contact lens, Habitual contact lens
- Volunteers
- 50 people
- Sponsor
- CIBA VISION
Myopia, Myopia; Refractive Error
Efficacy and Visual Quality of Orthokeratology Lenses With Different Designs
Orthokeratology (ortho-k) lens is very effective in slowing down axial elongation in myopic children by 30% to 63% when compared to children wearing single-vision spectacles or contact lenses.
- Trial name
- NCT06825585
- Testing
- Orthokeratology with 5.0mm back optical zone diameter, Orthokeratology with a 6.2 mm back optical zone diameter
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Xiaoyan Yang
Myopia, Progressive, Children, Only
Eleven Years of Menicon Z Night Contact Lens Wear in Reducing Myopia Progression in Children
To compare axial length growth of white European myopic children wearing Menicon Z Night orthokeratology contact lenses to a control group of distance, single-vision glasses and contact lenses over an 11-year period.
- Trial name
- MCOS11 (NCT04806711)
- Testing
- Menicon Z Night, Control
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Menicon Co., Ltd.
Myopia, Esophoria
Bifocal Soft Contact Lenses and Their Effect on Myopia Progression in Children and Adolescents.
The purpose of this study is to determine whether bifocal soft contact lenses are effective in controlling the progression of myopia in children and adolescents that exhibit a tendency to excessively cross their eyes while…
- Conditions
- Myopia, Esophoria, Fixation Disparity
- Trial name
- NCT00214487
- Testing
- Bifocal Contact Lenses
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Aller, Thomas A., OD
Myopia, Myopia Progression
Children's Viewing Behavior
The aim of this study is to investigate the area of the spectacle lens in which a subject is viewing through regardless of task being performed.
- Conditions
- Myopia, Myopia Progression, Juvenile Myopia
- Trial name
- NCT07229365
- Testing
- Novel spectacle lens design, Spectacle lens designs
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- SightGlass Vision, Inc.
Amblyopia
Morning Versus Evening Patching in Childhood Amblyopia
To determine whether the time of day at which daily occlusion therapy is administered-morning, with 2 hours of patching completed within 07:00-10:00, versus evening, with 2 hours completed within 17:00-20:00-affects visual-acuity…
- Trial name
- NCT07294599
- Testing
- eye-patching
- Where
- 2 sites in Jordan
- Volunteers
- 84 people
- Sponsor
- Yarmouk University
Myopia
Pharmacological and Non-pharmacological Treatment Effects on Children With Different Predicted Myopia Progression Rate
The goal of this clinical trial is to compare pharmacological and non-pharmacological treatment effects on the children with different predicted myopia progression rate measured by modified multifocal electroretinogram.
- Trial name
- NCT06282848
- Testing
- Atropine 0.05%, DIMS lens
- Where
- Hong Kong
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Loss of Visual Contrast Sensitivity, Near Vision
Visual Performance Following Implantation of Presbyopia Correcting IOLs
The purpose of the current study was to compare the visual performance after bilateral implantation of the Panoptix IOL , or the AT LISA IOL or Tecnis Symfony IOL .
- Conditions
- Loss of Visual Contrast Sensitivity, Near Vision, Visual Impairment
- Trial name
- NCT04907955
- Testing
- phacoemulsification with implantation of presbyopia correcting IOL
- Where
- Kuwait
- Volunteers
- 50 people
- Sponsor
- Dar Al Shifa Hospital
Myopia
the Effect of Low-Concentration Atropine Combined With Auricular Acupoint Stimulation in Myopia Control
To compare the effect of myopia control between patients treated with low-concentration atropine eye drops combined with auricular acupoint stimulation and those treated with atropine alone.
- Trial name
- NCT02055378
- Testing
- Atropine, auricular acupoint stimulation
- Where
- Taiwan
- Volunteers
- 73 people
- Sponsor
- Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation
Myopia, Myopic Macular Degeneration
Development and Validation of a Deep Learning-based Myopia and Myopic Maculopathy Detection and Prediction System
Myopia has become a global public health issue. Myopia affects the psychological health of children and adolescents and poses a financial burden.
- Trial name
- NCT05835115
- Testing
- A deep learning-based myopia and myopic maculopathy detection and prediction system
- Where
- China
- Volunteers
- 30,526 people
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center