Clinical trials: Refractive Error
Refractive Errors
Academic Performance and Refractive Error
Refractive errors constitute the leading cause of visual disability worldwide and that myopia progresses dramatically when students reach school age.
- Trial name
- NCT04338880
- Where
- China
- Volunteers
- 10,000 people
- Sponsor
- Sun Yat-sen University
Myopia
Myopia Progression Trial With Novel Myopia Control Design Spectacle Lenses
This is a mono-center, randomized, double-masked, cross-over study to evaluate rate of myopia progression with novel designed myopia control lens (test) compared to SVL (control).
- Trial name
- NCT04048148
- Testing
- Novel designed myopia control spectacle lenses
- Where
- Vietnam
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Brien Holden Vision Institute
Myopia
Spectacle Films Utilising S.T.O.P.® Technology for Slowing Down Myopia Progression in Children
There are two parts to this trial. First, to compare the rate of myopia progression of spectacle films using Spatio Temporal Optic Phase (S.T.O.P.®) technology that provide a dynamic optical cue against single vision spectacle…
- Trial name
- NCT06137560
- Testing
- Single vision spectacle lens, Single vision spectacle lens + S.T.O.P.® Kit 1, Single vision spectacle lens + S.T.O.P.® Kit 2
- Where
- 5 sites in China, India
- Volunteers
- 210 people
- Sponsor
- nthalmic Pty Ltd
Myopia
Myopia Control Using Soft Bifocal Lenses
The purpose of this study is to evaluate whether bifocal soft contact lenses (CLs) with low addition and nasally decentered optical zone are effective in controlling myopic progression in children.
- Trial name
- NCT02643758
- Testing
- Bifocal soft contact lenses
- Where
- Hong Kong
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Refractive Errors
The Effect of Gabapentin (Neurentin) and Pregabalin (Lyrica) in Pain Reduction After Photorefractive Keratectomy
The studied patients will be given randomly one of three following drugs1:Gabapentin2: Pregabalin or placebo for 3 days after Photorefractive keratectomy surgery.
- Trial name
- PRK (NCT01122004)
- Testing
- Pregabalin
- Where
- Iran
- Sponsor
- Shahid Beheshti University of Medical Sciences
Myopia
Characterization of the Central and Peripheral Wavefront Aberration Profile in Pediatric Myopic Subjects
This is a 3-visit, single site, observational clinical study to evaluate the characterization of the central and peripheral wavefront aberration profiles in pediatric myopic subjects.
- Trial name
- NCT06075576
- Testing
- Intervention
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Myopia
A Lifestyle Investigation With Spectacles and Daily Disposable Contact Lenses in Young Patients
The purpose of this study was to evaluate the relative benefits of daily disposable contact lenses versus spectacles in young adults.
- Trial name
- NCT01445652
- Testing
- nelfilcon A contact lens, Spectacles
- Where
- United Kingdom
- Volunteers
- 113 people
- Sponsor
- CIBA VISION
Myopia, Myopia; Refractive Error
Efficacy and Visual Quality of Orthokeratology Lenses With Different Designs
Orthokeratology (ortho-k) lens is very effective in slowing down axial elongation in myopic children by 30% to 63% when compared to children wearing single-vision spectacles or contact lenses.
- Trial name
- NCT06825585
- Testing
- Orthokeratology with 5.0mm back optical zone diameter, Orthokeratology with a 6.2 mm back optical zone diameter
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Xiaoyan Yang
Amblyopia, Refractive Errors
Vision Screening for the Detection of Amblyopia
INTRODUCTION. Amblyopia is defined as the loss of visual acuity (VA) in one or both eyes, without any obvious structural or pathological anomalies.
- Conditions
- Amblyopia, Refractive Errors, Anisometropia, Strabismus
- Trial name
- NCT01430247
- Testing
- Amblyopia screening
- Where
- Croatia
- Volunteers
- 7,000 people
- Sponsor
- Mladen Busic
Myopia
Comparison of Verofilcon A Daily Disposable Lenses to Somofilcon A Daily Disposable Lenses
The objective of the study is to evaluate and compare the performance of verofilcon A to somofilcon A when worn on a daily disposable modality over a period of approximately one week each.
- Trial name
- NCT04305912
- Testing
- somofilcon A, verofilcon A
- Where
- Canada
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Cataract With Pre-existing Regular Corneal Astigmatism
Influence of Implantation Technique on Rotational Stability of a Frosted-Haptic Toric Intraocular Lens: A Prospective Contralateral-Eye Study
This prospective, randomized contralateral-eye study evaluates whether the implantation technique influences the rotational stability and refractive outcomes of the TECNIS Eyhance™ Toric II intraocular lens (IOL) during cataract…
- Trial name
- NCT07768722
- Testing
- OVD-assisted Implantation, BSS-assisted hydroimplantation
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Ain Shams University
Myopia (Disorder), Astigmatism
Optical Quality of the Cornea in Orthokeratology
Analyzing Optical Quality After the Use of Overnight Orthokeratology (Ortho-K)
- Trial name
- COPCORTO (NCT06775509)
- Testing
- Ortho-K
- Where
- Spain
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Institut Investigacio Sanitaria Pere Virgili
Myopia
The Use of Atropine 0.01% in the Prevention and Control of Myopia (ATOM3)
Study of low dose atropine in preventing the onset and progression of myopia in high risk children with pre-myopia or low-myopia.
- Trial name
- NCT03140358
- Testing
- Atropine sulfate 0.01%
- Where
- Singapore
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Singapore National Eye Centre
Myopia
A Contralateral Dispensing Clinical Trial of Study Test Silicone Hydrogel Lens Against Enfilcon A Silicone Hydrogel Lens
This will be a 1-month dispensing, double-masked, randomized, contralateral study comparing the test lens against the control lens. The assignment of lenses to eyes (i.e.
- Trial name
- NCT02537717
- Testing
- Sapphire Lens, enfilcon A
- Where
- Canada
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Myopia
To Evaluate the Effectiveness of New Specially Designed Fitlens Soft Lens.
Myopia is a common disorder, affecting approximately one-third of the US population and over 90% of the population in some East Asian countries.
- Trial name
- NCT05433792
- Testing
- Myolens CN (Central-Near) soft contact lens, MiSight® soft contact lens
- Where
- Israel
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Fitlens Ltd.
Myopia
A Singapore Pilot Study to Assess Neurovision in Treatment of Low Myopia
To assess how well and safe is Neurovision technology in improving the vision of people with low myopia in Singapore
- Trial name
- NCT00348127
- Testing
- Neurovision
- Where
- Singapore
- Sponsor
- Singapore National Eye Centre
Visual Developmental Disorders
Tertiary Care for Visual Developmental Disorders in Pre-school Children
Visual development disorders are major public health problems among children especially in China. How to find an effective and economic way to manage the larger number of children in China remains exploring.
- Trial name
- NCT03251456
- Testing
- Tertiary care, Usual Care
- Where
- China
- Volunteers
- 1,114 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Myopia
Baseline Relative Peripheral Refraction in Myopia Control
Myopia has become a world concern and its prevalence has increased in recent decades. Myopic defocus has been applied for slowing down the axial elongation and myopia progression, which is mainly based on the theory of…
- Trial name
- NCT06161311
- Testing
- DIMS lenses
- Where
- Hong Kong
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Nearsightedness, Farsightedness
Advanced Surface Ablation (ASA) vs Laser-Assisted In Situ Keratomileusis (LASIK)
The purpose of this combined retrospective and prospective chart review analysis is to investigate the safety, efficacy, and predictability obtained via Laser-Assisted In Situ Keratomileusis (LASIK) and Advanced Surface Ablation…
- Conditions
- Nearsightedness, Farsightedness, Astigmatism
- Trial name
- NCT00778570
- Where
- Canada
- Volunteers
- 4,000 people
- Sponsor
- Ottawa Hospital Research Institute
Partially Accommodative Esotropia
Medial Rectus Fenestration vs Recession for PAET
This prospective comparative study aims to compare medial rectus (MR) muscle fenestration and recession in patients with partially accommodative esotropia (PAET).
- Trial name
- NCT06298929
- Testing
- medial rectus fenestration, medial rectus recession
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Mansoura University