Clinical trials: Refractive Error
Myopia
650nm Low-level Red-light for Myopia Control and Prevention in Children
A multicenter randomized controlled trial, evaluating the efficacy and safety of 650nm low-level red-light irradiation for myopia control and prevention in children.
- Trial name
- NCT05786586
- Testing
- 650 nm low-level red-light
- Where
- China
- Volunteers
- 572 people
- Sponsor
- Beijing Tongren Hospital
Myopia Progression, Axial Length, Eye
Low Dose Atropine Eye Drops in Myopic Egyptian Children
Previous Studies reported that low concentration atropine eye drops may be effective in increasing the choroidal blood flow and thickness and this slows myopia progression.
- Conditions
- Myopia Progression, Axial Length, Eye, Sclera Thickness
- Trial name
- LAMP (NCT06265454)
- Testing
- low dose atropine eye drops
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Ain Shams University
Myopia, Progressive, Atropine Allergy
Eye Drops Study for Myopia Control in Schoolchildren
The myopia prevalence in schoolchildren is high in Taiwan. The myopia progression is fast in children and often associated high myopia in later life.
- Trial name
- NCT03402100
- Testing
- eye drops
- Where
- Taiwan
- Volunteers
- 150 people
- Sponsor
- Chang Gung Memorial Hospital
Amblyopia, Strabismus
Screening for 3-D Visual Disorders in Preschool Children
Visual screening is necessary among pre-school children as they found themselves in a critical period of visual developement. To date, there are no national vision screening program that has been implemented nationwide.
- Conditions
- Amblyopia, Strabismus, Anisometropia
- Trial name
- VISION (NCT05204069)
- Testing
- Instillation of cyclopentolate
- Where
- France
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Myopia
Delaying the Onset of Nearsightedness Until Treatment Study
Participants eligible for the study will be randomized to one of three concentrations of atropine and followed for a month.
- Trial name
- DONUT (NCT06029530)
- Testing
- Atropine Ophthalmic
- Volunteers
- healthy volunteers welcome
- Sponsor
- Ohio State University
Myopia, Hyperopia
Corneal Asphericity Adjustment (Q Adjustment) in Myopic and Hyperopic Patients Undergoing Refractive Correction With Excimer Laser
To study the postoperative results in myopic and hyperopic eyes treated with two different laser ablation algorithms (STD and F-CAT), both FDA approved.
- Trial name
- NCT01296867
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Democritus University of Thrace
Myopia
Comparing Myopia Control Spectacle Lenses for Visual Comfort, Adaptation, and Satisfaction in Myopic Children
The goal of this clinical trial is to demonstrate that the visual comfort, adaptation, and overall satisfaction associated with the use of the test spectacle lenses are not inferior to those of the control spectacle lenses in…
- Trial name
- EVASION (NCT07683481)
- Testing
- HADAL Spectacle Lenses, Stellest® Spectacle Lenses
- Volunteers
- 20 people
- Sponsor
- Essilor International
Myopia
Short-term Clinical Performance of Multifocal Soft Contact Lens
The study is aimed to observe the short-term clinical performance of MiSight™ multifocal soft contact lens compared with Proclear™ 1day, including objective examination, subjective acceptability of wearers, and doctors'…
- Trial name
- NCT05273606
- Testing
- MiSight mutifocal soft contact lens, Proclear 1 Day soft contact lens
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Myopia
Shamir Aspheric Ophthalmic Lenses (MyLens) for Myopic Control Clinical Trial
The aim of this clinical trial is to compare the rate of myopic progression in children wearing aspheric (MyLens) and spherical/ toric ophthalmic lenses.
- Trial name
- NCT02700139
- Testing
- Aspheric lens
- Where
- Hong Kong
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Myopia
Phase 1 Study of SHJ002 Sterile Ophthalmic Solution in Pediatric Subjects
This is a single-center, open-label, first-in-human dose-escalation study of SHJ002 Ophthalmic Solution in children. (Part 1) Three (3) subjects will receive each concentration of SHJ002 for 3 days in an escalation design in one…
- Trial name
- NCT04928144
- Testing
- SHJ - Low concentration, SHJ - Mid concentration, SHJ - High concentration
- Where
- Taiwan
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Sunhawk Vision Biotech, Inc.
Myopia
MyopiaX Treatment for the Reduction of Myopia Progression in Children and Adolescents: Safety and Efficacy Investigation
The purpose of this trial is to investigate the safety and efficacy of MyopiaX - a digital treatment intended to slow the progression of myopia in children and adolescents.
- Trial name
- MyopiaX-1 (NCT04967287)
- Testing
- MyopiaX, Myopia control spectacles
- Where
- 10 sites in Germany, Netherlands and 3 more
- Volunteers
- 124 people
- Sponsor
- Dopavision GmbH
Myopia
Influence of Corneal Biomechanical Properties on Myopia Control
to analyze the changes in corneal biomechanics of myopic children with different treatment (low concentration atropine eye drops and orthokeratology) and explore the possible mechanism of myopia control
- Trial name
- NCT05090592
- Testing
- orthokeratology, 0.01 atropine
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Buddhist Tzu Chi General Hospital
Myopia; Refractive Error
The Initiating Factors of Myopia Among Primary and Secondary School Students in Tianjin
There was a prospective cohort observational study. Forty hyperopic children, 40 myopic children and 120 emmetropia children were randomly selected from grade 1 to grade 3, and were followed up every six months for 3 years.
- Trial name
- NCT05637827
- Testing
- No intervention
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Tianjin Eye Hospital
Myopia
Wavelength Intervention for Nearsighted Kids
The goal of this clinical trial is to learn if daily brief periods of specialized soft contact lens wear work to slow the progression of nearsightedness in children.
- Trial name
- WINK (NCT06598423)
- Testing
- Specialized soft contact lens 1, Specialized soft contact lens 2
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Myopia
Correction of Myopia Evaluation Trial 2
The purpose of the study is to determine if progressive addition lenses (PALs) versus single vision lenses (SVLs) slow the progression of low myopia in children with poor accommodative responses (i.e., large accommodative lags)…
- Trial name
- COMET2 (NCT00320593)
- Testing
- Progressive Addition Lenses (PALs), Single Vision Lenses (SVLs)
- Where
- 8 sites in United States
- Volunteers
- 118 people
- Sponsor
- Jaeb Center for Health Research
Ametropia
Evaluation of Disinfecting Solutions and Protein Remover With a Silicone Hydrogel Lens
The purpose of this study is to determine if reduced lens deposits and increased comfort can be achieved by using Multipurpose disinfecting solutions (MPDS) in a no-rub format but in conjunction with an intensive cleaner, rather…
- Trial name
- NCT00754338
- Testing
- Alcon Opti-Free® RepleniSH® with Supraclens®, Alcon Opti-Free® RepleniSH®, B&L ReNu MultiPlus™
- Where
- Canada
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- University of Waterloo
Refractive Errors, Hyperopia
School-based Myopia Prevention Trial for Children With Insufficient Hyperopic Reserve
This is a prospective, school-based randomized controlled trial designed to evaluate auricular acupressure for myopia prevention in non-myopic primary school students with insufficient hyperopic reserve.
- Conditions
- Refractive Errors, Hyperopia, Myopia
- Trial name
- SPARK (NCT07746804)
- Testing
- Auricular Acupressure, Eye Health Education
- Where
- China
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Myopia
Comparing Relative Peripheral Refraction on Myopia Progression
The investigators will test our hypothesis that parameters on peripheral defocus can regulate eye growth: For instance, the relative peripheral refraction measured by Multispectral Refraction Topography (MRT) would be significant…
- Trial name
- CMPMRT (NCT06758843)
- Testing
- measure the axial length, visual acuity, and refraction at follow-up of 6- and 12-month
- Where
- China
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- Fuzhou Southeast Institute of Visual Ophthalmology
Refractive Errors, Esotropia
Changes in Refractive Error in Patients With Both Partially Refractive Esotropia and Amblyopia
To investigate changes in refractive errors and evaluate clinical outcomes of strabismus surgery in patients with both amblyopia and partially refractive esotropia (PAET).Amblyopic patients with PAET were enrolled.
- Conditions
- Refractive Errors, Esotropia, Amblyopia Strabismic
- Trial name
- NCT04429659
- Where
- Turkey (Türkiye)
- Volunteers
- 58 people
- Sponsor
- Sakarya University
Bilateral Refractive Amblyopia
Bilateral Refractive Amblyopia Treatment Study
The purpose of this study will be to: Determine the amount of visual acuity improvement with treatment of presumed bilateral refractive amblyopia Determine the time course of visual acuity improvement with treatment
- Trial name
- ATS7 (NCT00305955)
- Testing
- Spectacles
- Where
- United States
- Volunteers
- 113 people
- Sponsor
- Jaeb Center for Health Research