Clinical trials: Refractive Error
Myopia
To Evaluate The Performance Of Two Monthly Replacement Silicone Hydrogel Contact Lenses After 1-month Of Wear
To evaluate the performance of two monthly replacement silicone hydrogel contact lenses in habitual FRP CL wearers when worn for 1-month.
- Trial name
- NCT05333965
- Testing
- Lens A (lehfilcon A lens), Lens B (comfilcon A lens)
- Where
- Canada
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Myopia
S.T.O.P.® Technology Contact Lenses Versus Dual-focus Contact Lenses for Slowing Down Myopia Progression in Children
To compare the rate of myopia progression of contact lenses utilising S.T.O.P.® technology against MiSight® contact lenses.
- Trial name
- NCT05243836
- Testing
- S.T.O.P® F2, S.T.O.P® DT, MiSight®
- Where
- 7 sites in China, India and 1 more
- Volunteers
- 441 people
- Sponsor
- nthalmic Pty Ltd
Cataract
Total Corneal Astigmatism Prevalence in Cataract Patients
The purpose of this study is to report the prevalence data for total corneal astigmatism (TCA) in cataract surgery candidates.
- Trial name
- NCT06148857
- Testing
- IOLMaster 700
- Where
- China
- Volunteers
- 11,000 people
- Sponsor
- Peking University Third Hospital
Cataract With Pre-existing Regular Corneal Astigmatism
Influence of Implantation Technique on Rotational Stability of a Frosted-Haptic Toric Intraocular Lens: A Prospective Contralateral-Eye Study
This prospective, randomized contralateral-eye study evaluates whether the implantation technique influences the rotational stability and refractive outcomes of the TECNIS Eyhance™ Toric II intraocular lens (IOL) during cataract…
- Trial name
- NCT07768722
- Testing
- OVD-assisted Implantation, BSS-assisted hydroimplantation
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Ain Shams University
Ocular Surface Disease, Irregular Astigmatism
Evaluation of the Safety and Efficacy of Rigid Breathable Scleral Contact Lenses for the Correction of Ametropia
To evaluate the short-term efficacy and safety of scleral contact lens in the clinical treatment of patients with irregular astigmatism after corneal transplantation by analyzing ocular parameters and ocular surface conditions of…
- Conditions
- Ocular Surface Disease, Irregular Astigmatism, Contact Lens Complication, Corneal Astigmatism
- Trial name
- NCT06256770
- Where
- China
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- Tianjin Eye Hospital
Myopia
Retardation of Myopia in Orthokeratology
The primary aim of this study is to evaluate and compare the eyeball elongation in children wearing orthokeratology lenses and single-vision spectacles.
- Trial name
- ROMIO (NCT00962208)
- Testing
- orthokeratology lenses, single-vision spectacle lenses
- Where
- China
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Myopia
Evaluating the Efficacy and Safety of Contact Lens Lubricant in Rigid Gas Permeable Corneal Contact Lens Wearers
This trial aims to evaluate the safety and effectiveness of LACRIFRESH OCU-DRY 0.3% OSD, a contact lens lubricant produced by AVIZOR, S.A.
- Trial name
- NCT07091825
- Testing
- LACRIFRESH OCU-DRY 0.3% OSD, Rigid contact lens lubricant
- Where
- 3 sites in China
- Volunteers
- 152 people
- Sponsor
- Avizor SA
Myopia
Clinical Investigation of a Novel Spectacle Lens on Slowing Down Juvenile Myopia Progression
The goal of this exploratory clinical trial is to evaluate the efficacy and safety of a test spectacle lens (standard single vision lens (SVL) during first year, and standard myopia control lens (MCL) in second year), designed…
- Trial name
- NCT06850168
- Testing
- SVL, SVL with passive red-light emission, MCL
- Where
- Singapore
- Volunteers
- 35 people
- Sponsor
- Essilor International
Refractive Errors
Evaluation of the Agreement Between Automated Program-Operated Phoropter Subjective Refraction and Optometrist-Performed Subjective Refraction
This study aims to evaluate the performance of an automated subjective refraction system that operates a digital phoropter. By comparing its results with those obtained through conventional subjective refraction performed by an…
- Trial name
- NCT07891897
- Testing
- Automated Program-Controlled Subjective Refraction, Optometrist-Performed Subjective Refraction
- Volunteers
- 508 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Myopia
Clinical Evaluation of Two Daily Disposable Lenses in Neophytes
The purpose of this study is to evaluate the performance of two daily disposable contact lenses in a population of neophytes (new wearers).
- Trial name
- NCT00987623
- Testing
- nelfilcon A contact lens, narafilcon A contact lens
- Where
- United States
- Volunteers
- 326 people
- Sponsor
- CIBA VISION
Myopia
1 Week Crossover Study Between Two Soft Contact Lenses
The objective of this investigation is to compare the visual clinical performance of two daily disposable soft contact lenses.
- Trial name
- NCT06611410
- Testing
- Test Lenses (stenfilcon A), Control Lenses (omafilcon A)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- CooperVision, Inc.
Myopia, Myopia, Progressive
Study to Evaluate the Efficacy of Alleance® (Atropine Sulfate 0.01%) as a Treatment to Delay Myopia and Axial Ocular Elongation in Children.
Phase III clinical study to evaluate the efficacy of Alleance® (atropine sulfate 0.01%) ophthalmic solution through the incidence of unexpected adverse events, changes in Best Corrected Visual Acuity (BCVA), changes in…
- Trial name
- NCT06389110
- Testing
- Alleance®
- Where
- Mexico
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Laboratorios Sophia S.A de C.V.
Myopia
Investigating the Safety and Effect of Overnight Orthokeratology and Its Influencing Factors
To investigate the Safety and Effect of Overnight Orthokeratology and Its Influencing Factors in China
- Trial name
- NCT04910451
- Testing
- No Intervention
- Where
- China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Myopia
To Evaluate the Efficacy and Safety of Aspherical Soft Contact Lens in Myopia Control
The objective of this study is to demonstrate that the Ticon Aspherical Daily Disposable Soft Contact Lens could retard myopia progress in youth
- Trial name
- NCT04238897
- Testing
- soft contact lens
- Volunteers
- 72 people
- Sponsor
- APP Vision Care Inc.
Myopia
Sustained Effect of Red-light Therapy for Myopia Control: A 2-Year Post-Trial Follow-up Study
To evaluate the long-term efficacy and safety of red-light therapy for myopia control over 2 years, and the potential rebound effect after treatment cessation.
- Trial name
- NCT06232161
- Testing
- Red-light therapy device, Spectacles
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Beijing Airdoc Technology Co., Ltd.
Myopia
Myopia Control Effect of DIMS Spectacle Lenses in Czech Children and Young Adults
The aim of this clinical study is to compare the efficacy of DIMS technology spectacle lenses with conventional single vision spectacle lenses at slowing the progression of myopia in the category of children and young adults…
- Trial name
- NCT05943912
- Testing
- Single Vision Spectacle Lens, Defocus Incorporated Multiple Segments (DIMS) Spectacle Lens
- Where
- Czechia
- Volunteers
- 80 people
- Sponsor
- Czech Technical University in Prague
Myopia
Efficacy of Topical Atropine Eye Drops for Control of Myopia Progression Among Children Attending Mansoura University Ophthalmic Center
This randomized controlled trial aims to evaluate the efficacy and safety of low-dose topical atropine sulphate (0.05%), a non-selective muscarinic antagonist, in slowing the progression of myopia and ocular axial elongation in…
- Trial name
- NCT07164092
- Testing
- Atropine 0.05% Eye drops
- Volunteers
- 45 people
- Sponsor
- Mansoura University
Myopia, Child Myopia Progression
Photolithography Microstructure Myopia Management Lenses in Preventing and Controlling Myopia in Children and Adolescents
Evaluate the effectiveness of different lithographic microstructured myopia management lenses in controlling the progression of myopia in children and adolescents, as well as the safety and comfort of wearing them.
- Trial name
- NCT07514039
- Testing
- Myopia management lens
- Where
- China
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Anisometropia, Hyperopia
Effect of Light-Blocking Lenses on Hyperopic Anisometropic Children
To evaluate the effectiveness of light-blocking lenses in promoting emmetropization and reducing anisometropia in children with hyperopic anisometropia, and to assess the impact of light-intercepting lenses on visual function in…
- Trial name
- NCT07142928
- Testing
- light-blocking lenses, single-vision lenses
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Myopia, Myopia Progression
Spectacle Lens Visual Acuity Assessments Study
This is a two-arm parallel group, non-dispensing study. Participants will be existing active CYPRESS Extension (CPRO-1802-002) subjects. Subjects will undergo additional visual performance assessments.
- Conditions
- Myopia, Myopia Progression, Juvenile Myopia
- Trial name
- CEDAR (NCT05650190)
- Testing
- Novel spectacle lens design, Spectacle lenses
- Where
- 6 sites in United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- SightGlass Vision, Inc.