Clinical trials: Refractive Error - Myopia
Myopia
Phase 1 Study of SHJ002 Sterile Ophthalmic Solution in Pediatric Subjects
This is a single-center, open-label, first-in-human dose-escalation study of SHJ002 Ophthalmic Solution in children. (Part 1) Three (3) subjects will receive each concentration of SHJ002 for 3 days in an escalation design in one…
- Trial name
- NCT04928144
- Testing
- SHJ - Low concentration, SHJ - Mid concentration, SHJ - High concentration
- Where
- Taiwan
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Sunhawk Vision Biotech, Inc.
Myopia
Controlling Myopia Progression With Soft Contact Lenses (Contact Lens Control)
This study is to investigate whether novel soft contact lens optical designs can slow myopia progression
- Trial name
- NCT01829191
- Testing
- Soft Contact Test Lens A, Soft Contact Test Lens C
- Where
- United States
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Myopia, Myopia, Progressive
Effect of Virtual Reality-Based Visual Training for Myopia Control in Children
To assess the efficacy and safety of virtual reality-based visual training (VRVT) in myopia control among children.
- Trial name
- NCT06250920
- Testing
- Virtual reality visual training
- Where
- China
- Volunteers
- 65 people
- Sponsor
- Shanghai 10th People's Hospital
Myopia
A Dispensing Clinical Trial of a Study Test Silicone Hydrogel Lens Against Control Lens Over 1 Week
This is a 1-week dispensing, double-masked, randomized, bilateral study comparing the test lens against the control lens.
- Trial name
- NCT02500368
- Testing
- silicone hydrogel lens (test), enfilcon A lens (control)
- Where
- Canada
- Volunteers
- 41 people
- Sponsor
- CooperVision, Inc.
Pediatric Cataract, IOL Implantation
Myopia Progression Control Using Atropine 0.05% After Pediatric Cataract Surgery And Intraocular Lens Implantation Surgery
Myopic shift remains a debilitating and unpredictable adverse event following pediatric cataract surgery. While research exploring peripheral myopic defocus for post-cataract surgery myopia prevention shows promising results, the…
- Conditions
- Pediatric Cataract, IOL Implantation, Myopia Progression
- Trial name
- NCT07364370
- Testing
- Atropine Eye drops
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Myopia
Evaluate the Efficacy and Safety of CTO0308 in Pediatric Patients With Myopia
This study was to evaluate the superiority of the myopia progression control effect in the treatment group compared with the control group, evaluated by the change in spherical equivalent (SE) after 12 months of administration of…
- Trial name
- NCT07790640
- Testing
- CTO0308
- Where
- South Korea
- Volunteers
- 351 people
- Sponsor
- Taejoon Pharmaceutical Co., Ltd.
Myopia, Mental Health
Intervention for Preventing Myopia and Multimorbidity in Children
This study aims to develop and evaluate a scalable, hybrid intervention model for the co-prevention of myopia, obesity, and mental health issues among children.
- Conditions
- Myopia, Mental Health, Cardiovascular Health Status
- Trial name
- NCT07294222
- Testing
- Standard School Health Education, Multi-component Health Promotion Package
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Fangbiao Tao
Myopia, Refractive Errors
Prevalence and Environmental Factors for Myopia Among Chinese School-aged Children and Adolescent in Tianjin
The high prevalence of myopia has become a global public health problem. The study amied to investigate the prevalence and progression of myopia associated with social environmental factors in Tianjin, a Chinese megacity in north…
- Trial name
- NCT05336799
- Where
- China
- Volunteers
- 500,000 people, healthy volunteers welcome
- Sponsor
- Tianjin Eye Hospital
Myopia
A Singapore Study to Assess How Neurovision Improve the Vision of Adults With Low to Moderate Myopia
To evaluate the efficacy of NeuroVision NVC vision correction technology to improve the vision of subjects with Low and Moderate Myopia in Asian eyes in Singapore
- Trial name
- NCT00348075
- Testing
- Neurovision
- Where
- Singapore
- Sponsor
- Singapore National Eye Centre
Refractive Errors
Correcting Myopia Among Secondary School Children to Increase Academic High School Attendance Rates in Rural Communities
Chinese children are some of the most short-sighted in the world, but only one in five children in poor areas who needs glasses has them.
- Trial name
- SWISH (NCT04077086)
- Testing
- Spectacles
- Where
- 3 sites in China, United Kingdom
- Volunteers
- 10,000 people
- Sponsor
- Queen's University, Belfast
Progressive Myopia
MAD Trial: Myopia Atropine Dose
The goal of this interventional study is to compare the efficacy of Atropine 0.05% to Atropine 0.5% treatment against progression of axial length in European children with progressive myopia, and to evaluate the safety…
- Trial name
- MAD (NCT05667454)
- Testing
- Atropine Ophthalmic 0.05%, Atropine Ophthalmic 0.5%
- Where
- 20 sites in Netherlands
- Volunteers
- 550 people
- Sponsor
- Erasmus Medical Center
Emmetropization, Myopia
Focus-out Glasses on Emmetropization in Chinese Children
The purpose of this study is to characterize the effects of peripheral focous-out glasses on emmetropization in non-myopic Chinese Children Aged 6-8 Years.This is a prospective, parallel-controlled randomized trial.
- Conditions
- Emmetropization, Myopia, Hyperopia
- Trial name
- NCT05689567
- Testing
- DEFOG glasses(peripheral focus-out glasses)
- Where
- China
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Fudan University
Myopia
WEAR (Wearability and Evaluation of Adjustable Refraction) III
Two-month randomized trial comparing three groups.
- Trial name
- WEARIII (NCT02529540)
- Testing
- Adjustable glasses, Custom standard glasses, Ready-made glasses
- Volunteers
- 324 people
- Sponsor
- Sun Yat-sen University
no Obvious Abnormalities, Diabetic Retinopathy (DR)
Retinal Clinical Assessment With AI-derived Quantitative Information
This randomized controlled trial evaluates whether providing clinicians with AI-derived quantitative retinal information improves the quality and efficiency of retinal clinical assessment.
- Conditions
- no Obvious Abnormalities, Diabetic Retinopathy (DR), AMD, Cup-to-disc Ratio Bigger Than 0.5
- Trial name
- NCT07291960
- Testing
- AI-derived retinal quantitative information-assisted reporting
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Beijing Tongren Hospital
Myopia
Effect of Plum-blossom Needle vs. Tropicamide Eye Drops on Juvenile Myopia
The purpose of this study is to determine whether plum-blossom needle is effective in the treatment of juvenile myopia and compare the efficacy with Tropicamide Eye Drops.
- Trial name
- NCT03097198
- Testing
- Plum-blossom Needle, Tropicamide Eye Drops
- Where
- China
- Volunteers
- 98 people
- Sponsor
- Wenzhou Medical University
Presbyopia
Safety and Efficacy of an Intrastromal Transform™ Corneal Allograft (TCA) for Presbyopia Correction
The objective of this clinical study is to evaluate the safety and effectiveness of intrastromal implantation of the Allotex TransForm corneal allograft (TCA) for improving near vision in presbyopic subjects.
- Trial name
- NCT03671135
- Testing
- TCA Intrastromal Inlay
- Where
- 4 sites in Belgium, Ireland and 1 more
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Allotex, Inc.
Myopia
A Clinical Trial to Evaluate the Efficacy and Safety of Defocusing Lenses in Delaying Myopia Progression
The objective of this clinical trial was to evaluate the efficacy and safety of defocusing lenses for delaying myopia progression in children and adolescents.
- Trial name
- NCT06411717
- Testing
- Microstructure lens A, Microstructure lens B, Control group
- Where
- China
- Volunteers
- 156 people
- Sponsor
- Suzhou Care-Real Medical Technology Co., Ltd.
Juvenile Myopia
Control of Myopia Using Novel Spectacle Lens Designs
Randomized, controlled, multisite, subject-and observer-masked, 3-arm parallel group clinical trial of 36-month duration to evaluate the safety and efficacy of a novel spectacle lens design in reducing the progression of juvenile…
- Trial name
- CYPRESS (NCT03623074)
- Testing
- Novel spectacle lens design, Spectacle lenses
- Where
- 14 sites in United States, Canada
- Volunteers
- 266 people, healthy volunteers welcome
- Sponsor
- SightGlass Vision, Inc.
Myopia
Prevention of Myopia of Prematurity by Calcium Supplementation
The purpose of this study is to determine if supplementation of calcium by the enteral route (gut feeding) to extremely low birth weight infants will lead to less myopia (nearsightedness) at 6-12 months postnatal age.
- Trial name
- NCT00892476
- Testing
- Calcium Supplementation, Standard of Care
- Volunteers
- 99 people
- Sponsor
- University of Alabama at Birmingham
Myopia
Clinical Comparison of Two Daily Disposable Lenses Among Daily Disposable Lens Wearers
The primary objective of this trial is to evaluate the subjective performance of two different daily disposable contact lenses in a population of daily disposable lens wearers.
- Trial name
- NCT01134211
- Testing
- nelfilcon A, filcon II 3
- Where
- Germany
- Volunteers
- 316 people
- Sponsor
- CIBA VISION