Clinical trials: Refractive Error - Myopia
Myopia
Acuity 200™ (Fluoroxyfocon A) Orthokeratology Contact Lens for Overnight Wear
The objective of this clinical investigation is to collect scientifically valid safety and effectiveness data on the Acuity 200™ (fluoroxyfocon A) Orthokeratology Contact Lens for Overnight Wear.
- Trial name
- Acuity200OK (NCT06009458)
- Testing
- Acuity 200™ (fluoroxyfocon A) Orthokeratology Contact Lens for Overnight Wear
- Where
- 13 sites in United States, Australia and 1 more
- Volunteers
- 387 people
- Sponsor
- Acuity Polymers, Inc.
Refractive Errors, Hyperopia
School-based Myopia Prevention Trial for Children With Insufficient Hyperopic Reserve
This is a prospective, school-based randomized controlled trial designed to evaluate auricular acupressure for myopia prevention in non-myopic primary school students with insufficient hyperopic reserve.
- Conditions
- Refractive Errors, Hyperopia, Myopia
- Trial name
- SPARK (NCT07746804)
- Testing
- Auricular Acupressure, Eye Health Education
- Where
- China
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Myopia
Effectiveness of DIMS Spectacle as a Function of the Age
Purpose: To evaluate the effectiveness of Defocus Incorporated Multiple Segments (DIMS) in slowing myopia progression as a function of age in pediatric patients.
- Trial name
- NCT06556849
- Testing
- Defocus Incorporated Multiple Segments (DIMS)
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- Luca Buzzonetti
Refractive Errors, Myopia (Disorder)
Environmental Health and Myopia Prevention and Control
Myopia is one of the major causes of low visual acuity during childhood. It is generally more prevalent in urban areas than in rural areas.
- Trial name
- NCT04161326
- Where
- China
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Myopia
Eye Exercise, Transcutaneous Electrical Nerve Stimulation on Prevention of Myopia Progression
In Taiwan, the increasing prevalence of myopia shows a decline with age. Myopia has become a serious ocular problem in children because high myopia may lead to retinal damage, cataract and glaucoma.
- Trial name
- NCT04017234
- Testing
- frequency following response, eye exercise, and transcutaneous
- Where
- Taiwan
- Volunteers
- 27 people
- Sponsor
- China Medical University Hospital
Myopia
A Controlled Evaluation of Optical Defocus Parameters on Transient Changes in Axial Length Using Kubota Glass
This study will assess the optimal performance characteristics of optical defocus on transient changes in axial length with Kubota Glass, using a randomized, double-masked, 5-treatment, 5-period crossover design with…
- Trial name
- NCT07686289
- Testing
- KG1, KG2, KG3
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Kubota Vision Inc.
Myopia, Repeated Low-level Red Light
Real-world Registry Study of Red Light Treatment on Myopia Control: a Focus on Non-responders to Conventional Treatments
This real-world observational registry study aims to assess the effectiveness of Repeated Low-Level Red Light (RLRL) therapy in controlling myopia progression among children aged 8 to 16 who have not responded to conventional…
- Trial name
- NCT06569810
- Testing
- Repeated Low-Level Red Light (RLRL) therapy
- Volunteers
- 2,500 people
- Sponsor
- The Hong Kong Polytechnic University
Myopia
Trial of Myopia Prevention Using +3D Lenses
The purpose of this study is to assess whether a short-term imposed myopic defocus is effective in preventing the development and progression of juvenile-onset myopia in Chinese children.
- Trial name
- PLS (NCT00627874)
- Testing
- +3D Lenses
- Volunteers
- 1,200 people
- Sponsor
- Sun Yat-sen University
Juvenile Myopia, Myopia
CYPRESS Efficacy and Safety Study Extension
This is an open-label, controlled, multisite, two-arm parallel group clinical trial of 36-month duration to evaluate the continued safety and efficacy of SightGlass Vision Diffusion Optics Technology (DOT) Spectacles in reducing…
- Trial name
- CYPRESS (NCT04947735)
- Testing
- Novel spectacle lens design, Spectacle lenses
- Where
- 12 sites in United States, Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- SightGlass Vision, Inc.
Myopia
A Singapore Study to Assess How Neurovision Improve the Vision of Adults With Low to Moderate Myopia
To evaluate the efficacy of NeuroVision NVC vision correction technology to improve the vision of subjects with Low and Moderate Myopia in Asian eyes in Singapore
- Trial name
- NCT00348075
- Testing
- Neurovision
- Where
- Singapore
- Sponsor
- Singapore National Eye Centre
Corneal Disease, Pterygium
Corneal Epithelium Repair and Therapy Using Autologous Limbal Stem Cell Transplantation
Corneal disease is a leading cause of blindness in the world. A shortage of corneal donor tissue has prevented many patients from regaining vision.
- Conditions
- Corneal Disease, Pterygium, Myopia, Hyperopia
- Trial name
- NCT02148016
- Testing
- LSCs and amniotic membrane (Modified Technique), Amniotic membrane only (Traditional Technique), PRK, LSCs, and amniotic membrane (Modified Technique)
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Sun Yat-sen University
Refractive Errors
Seeing to Learn in Sierra Leone
The main objective of the Sierra Leone Sees to Learn (SL2) trial is to assess the educational impact of providing free eyeglasses to students aged 9-20 years with uncorrected refractive error in Sierra Leone.
- Trial name
- SLII (NCT06065631)
- Testing
- Eyeglasses, Prescription slip
- Where
- Sierra Leone
- Volunteers
- 1,821 people
- Sponsor
- University of Minnesota
Myopia
Myopia Prevalence in Canadian School Children - a Pilot Study
The goal of this study is to determine the prevalence of nearsightedness in Canadian school children living in the Waterloo Region.
- Trial name
- Falcon (NCT01942057)
- Where
- Canada
- Volunteers
- 173 people, healthy volunteers welcome
- Sponsor
- University of Waterloo
Myopia
Phase 1 Study of SHJ002 Sterile Ophthalmic Solution in Pediatric Subjects
This is a single-center, open-label, first-in-human dose-escalation study of SHJ002 Ophthalmic Solution in children. (Part 1) Three (3) subjects will receive each concentration of SHJ002 for 3 days in an escalation design in one…
- Trial name
- NCT04928144
- Testing
- SHJ - Low concentration, SHJ - Mid concentration, SHJ - High concentration
- Where
- Taiwan
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Sunhawk Vision Biotech, Inc.
Myopia
Effect of Low-level Red-light on Ultra-high Myopia
100 eyes of ultra-high myopia were treated with daily low-level red-light. The age of children ranged from 3 to 16.3 years. The follow-up duration was one year.
- Trial name
- NCT06738095
- Testing
- daily low-level red-light
- Where
- China
- Volunteers
- 57 people
- Sponsor
- Beijing Tongren Hospital
Myopia
The Beijing Childhood Eye Study
Axial myopia has emerged as the leading cause of irreversible vision loss in East Asia, driven by its progression to sight-threatening complications including myopic macular degeneration, retinal detachment, open-angle glaucoma…
- Trial name
- BCES (NCT06931444)
- Where
- China
- Volunteers
- 3,760 people, healthy volunteers welcome
- Sponsor
- Beijing Tongren Hospital
Myopia
Evaluate the Safety and Efficacy of Two Types of Circular Column Modulated Lenses for Delaying the Progression of Myopia
Clinical trial to evaluate the safety and effectiveness of two kinds of ring band cylindrical lens in delaying the progression of myopia
- Trial name
- NCT05288335
- Testing
- Circular cylindrical mirror modulated frame glasses (compact), Circular cylindrical mirror modulated frame glasses (strong defocus), single vision frame glasses
- Where
- China
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Tianjin Eye Hospital
Myopia, Progressive
Double Helix Design Defocus Lens Spectacle (RACE) for Myopia Control
This study uses 1.585 double helix defocus lens PC lenses with a unique optical design that includes a globally coherent visible area and complementary left and right helices that can form clear images.
- Trial name
- NCT05894382
- Testing
- Double Helix Design Defocus Lens Spectacle (RACE), single-vision spetacle lens
- Where
- China
- Volunteers
- 236 people
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Myopia, Progressive
A Study of SHJ002 Sterile Ophthalmic Solution for Myopia Control
The objective of this study is to explore the safety and efficacy of SHJ002 Sterile Ophthalmic Solution relative to atropine in myopia control SHJ002 is an antisense oligonucleotide to neutralize a specific microRNA.
- Trial name
- NCT06579287
- Testing
- SHJ002, Atropine
- Where
- 9 sites in United States, Taiwan
- Volunteers
- 140 people
- Sponsor
- Sunhawk Vision Biotech, Inc.
Myopia
A Comparative Analysis of Myopia Prevalence Among Madarsa Students vs. Non-Madarsa Students in Sukkur
Myopia (nearsightedness) has become a major global health concern, particularly among students, due to factors such as prolonged screen time, close-up work, and limited outdoor activities.
- Trial name
- NCT06913972
- Where
- Pakistan
- Volunteers
- 364 people
- Sponsor
- Superior University