Clinical trials: Refractive Error - Myopia
Myopia
The Effects of Low-dose Atropine and Orthokeratology in Pediatric Myopia Control
Both orthokeratology and atropine eye drops are effective methods for myopia control, but few studies have compared them all together simultaneously.
- Trial name
- AVO (NCT05478356)
- Testing
- low-dose atropine eye drops, orthokeratology
- Where
- 2 sites in China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Evidence Based Cataract Study Group
Hyperopia and Myopia
Eye Imaging for the Study of Childhood Myopia
Myopia (nearsightedness) is increasing worldwide and is becoming a serious public health problem. Studies estimate that by 2050, if no action is taken, almost half of the world's population will be myopic.
- Trial name
- SELENA (NCT07335146)
- Testing
- Ophtalmic measurements to estimate geometrical distances, MRI, Ophtalmic measurements to measure wavefront aberrations
- Where
- France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Essilor International
Myopia, Pre-myopia
A Pilot Evaluation of Refractive Error Progression in Pre-Myopic Children in Singapore With and Without Myopia Control Spectacles
This study aims to find out whether ZEISS MyoActive lenses can help prevent short-sightedness from developing in children. We aim to recruit at least 50 children in total for this study.
- Trial name
- NCT07779941
- Testing
- Zeiss MyoActive lenses, Single Vision Lenses
- Where
- Singapore
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Singapore National Eye Centre
Myopia
Comparative Clinical Evaluation of Daily Disposable Lenses in Symptomatic Lens Wearers
The purpose of this trial is to evaluate the extent to which symptoms improve in symptomatic contact lens wearers when fit with one of 5 different daily disposable contact lenses.
- Trial name
- NCT00953407
- Testing
- Nelfilcon A contact lens, Narafilcon A contact lens, Etafilcon A contact lens
- Volunteers
- 128 people
- Sponsor
- CIBA VISION
Cataract, High Myopia
Artificial Intelligence for Highly Myopic Cataract
This study aims to establish a multi-center artificial intelligence model for the accurate calculation of intraocular lens and its clinical application in highly myopic cataract, so as to improve the accuracy of the prediction of…
- Conditions
- Cataract, High Myopia, Myopia, Automatic Judgement
- Trial name
- AI-HMC (NCT06616506)
- Testing
- newly-invented AI model
- Where
- China
- Volunteers
- 500,000 people
- Sponsor
- Shanghai High Myopia Study Group
Myopia; Refractive Error
The Initiating Factors of Myopia Among Primary and Secondary School Students in Tianjin
There was a prospective cohort observational study. Forty hyperopic children, 40 myopic children and 120 emmetropia children were randomly selected from grade 1 to grade 3, and were followed up every six months for 3 years.
- Trial name
- NCT05637827
- Testing
- No intervention
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Tianjin Eye Hospital
Myopia
Effects of Contact Lens Wear on Children's Self-Perceptions
The purpose of the study is to determine whether contact lens wear will improve children's self-perceptions more than spectacle wear.
- Trial name
- ACHIEVE (NCT00522288)
- Testing
- Soft contact lenses, Spectacle
- Where
- 5 sites in United States
- Volunteers
- 484 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Myopia, Myopia; Refractive Error
Peripheral Relative Refractive Power of Orthokeratology Lenses
Orthokeratology (OK) has been demonstrated to be an effective intervention for slowing axial elongation in children with myopia.
- Trial name
- NCT07294404
- Testing
- orthokeratology
- Where
- China
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Tianjin Eye Hospital
Myopia
Comparing Myopia Control Spectacle Lenses for Visual Comfort, Adaptation, and Satisfaction in Myopic Children
The goal of this clinical trial is to demonstrate that the visual comfort, adaptation, and overall satisfaction associated with the use of the test spectacle lenses are not inferior to those of the control spectacle lenses in…
- Trial name
- EVASION (NCT07683481)
- Testing
- HADAL Spectacle Lenses, Stellest® Spectacle Lenses
- Volunteers
- 20 people
- Sponsor
- Essilor International
Myopia, Visual Diet
Longitudinal Measurements of Visual Diet in Children
Myopia is a leading cause of visual impairment worldwide, with prevalence rising rapidly among children. Growing evidence suggests that environmental and behavioral factors play a dominant role in ocular growth; however, current…
- Conditions
- Myopia, Visual Diet, Pupil, Viewing Distance
- Trial name
- VEET (NCT07642999)
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- State University of New York College of Optometry
Myopia
Myopia Control With the Multi-segment Lens
The purpose of this study is to determine if the Multiple-Segment (MS) spectacle lens can slow myopia progression in Hong Kong schoolchildren. MS lens is also called Defocus Incorporated Multiple Segments (DIMS) spectacle lens
- Trial name
- NCT02206217
- Testing
- Multiple-Segment spectacle lens
- Where
- 2 sites in China, Hong Kong
- Volunteers
- 183 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Myopia, Progressive
Slow Myopia Progression With Different Irradiance Light
It is a prospective clinical control study on red light control myopia with specail design spectacles for 75 children in 3 groups. Study Groups with two different powers of 0.6 mW and 1.2 mW at wavelength of 650nm.
- Trial name
- NCT05881655
- Testing
- Airdoc Red Lighting Device, Special Spectacles to Control Myopia
- Where
- China
- Volunteers
- 75 people
- Sponsor
- Beijing Airdoc Technology Co., Ltd.
Myopia
Refitting Frequent Replacement Lens Wearers Into Clariti 1 Day And 1-Day Acuvue Moist Daily Disposable Spherical Lenses
The objective of the study is to evaluate and compare the performance of somofilcon A to etafilcon A when worn on a daily disposable wear modality over a period of approximately one week.
- Trial name
- NCT04195893
- Testing
- somofilcon A, etafilcon A
- Where
- Canada
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Myopia
Validation of the Utility of Myopia Intelligent Diagnostic System
The screening of myopia via artificial intelligence represents an challenge in computational medicine. Here, the investigators use "deep learning" to create an automatic diagnostic system for myopia screening using ocular…
- Trial name
- NCT04014725
- Testing
- Myopia Intelligent Diagnostic System
- Volunteers
- 50 people
- Sponsor
- Sun Yat-sen University
Myopia
The Effect of +3.00ADD on Myopia Progression in Chinese Children
The purpose of this study is to evaluate the effect of +3.00ADD vs single vision spectacle on the progression of myopia in children.
- Trial name
- NCT03242226
- Testing
- two spectacles, single vision spectacles
- Where
- China
- Volunteers
- 440 people
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Myopia, Progressive
Myopia Preventing With Distance-image Screen
This study is for testing the efficacy and safety of distance-image screens for preventing myopia in children for 12 month. Each subjects would be asked to paired test the ocular parameters between before and after 12-month…
- Trial name
- DIS (NCT06088225)
- Testing
- distance-image screen
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Beijing Airdoc Technology Co., Ltd.
Myopia
A Clinical Study to Evaluate the Remote Monitoring of Myopia Patients With the EyeQue Insight
The objective of this study is to determine whether the remote monitoring of myopia patients with the EyeQue Insight (visual acuity test) can replace regularly scheduled follow-up visits.
- Trial name
- NCT04693260
- Testing
- Visual Acuity with a Hand-held Device Supported by Mobile App.
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- EyeQue Corp.
Myopia
Brimonidine Eye Drops in the Prevention of Myopia Progression
Study to determine the efficacy of alpha-2 adrenergic drugs (brimonidine) in the prevention of myopia progression. Given that the drugs used so far have limited efficacy and side effects (loss of near vision, photophobia), it may…
- Trial name
- NCT06996236
- Testing
- Treatment with brimonidine eye drops 0.025%
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal
Myopia
To Evaluate the Effectiveness of New Specially Designed Fitlens Soft Lens.
Myopia is a common disorder, affecting approximately one-third of the US population and over 90% of the population in some East Asian countries.
- Trial name
- NCT05433792
- Testing
- Myolens CN (Central-Near) soft contact lens, MiSight® soft contact lens
- Where
- Israel
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Fitlens Ltd.
Myopia
Control of Myopia in Young Children Using H.O.P.E. Lenses Combined With 0.02% Atropine Eye Drops
A multicenter, prospective, intervention study on the control of myopia in young children using high-order phase element array microstructure lenses (H.O.P.E.) in combination with low-concentration atropine eye drops (0.02%)
- Trial name
- NCT07846787
- Testing
- High-order Phase Element Array Microstructure Design Lens (H.O.P.E.), 0.02% Atropine Sulfate Eye Drops
- Where
- China
- Volunteers
- 264 people
- Sponsor
- Ruihua Wei